{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:04:28Z","timestamp":1781841868561,"version":"3.54.5"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T00:00:00Z","timestamp":1573776000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T00:00:00Z","timestamp":1573776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Societ\u00e0 Italiana di Nutrizione Artificiale e Metabolismo-SINPE"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Nephrol"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1007\/s40620-019-00659-2","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T06:03:02Z","timestamp":1573797782000},"page":"109-117","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Validation by CT scan of quadriceps muscle thickness measurement by ultrasound in acute kidney injury"],"prefix":"10.1093","volume":"33","author":[{"given":"Alice","family":"Sabatino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Regolisti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"di Mario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ciuni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anselmo","family":"Palumbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Peyronel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Maggiore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6532-7675","authenticated-orcid":false,"given":"Enrico","family":"Fiaccadori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,11,15]]},"reference":[{"issue":"15","key":"659_CR1","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1001\/jama.2013.278481","volume":"310","author":"ZA Puthucheary","year":"2013","unstructured":"Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, Hopkinson NS, Phadke R, Dew T, Sidhu PS, Velloso C, Seymour J, Agley CC, Selby A, Limb M, Edwards LM, Smith K, Rowlerson A, Rennie MJ, Moxham J, Harridge SD, Hart N, Montgomery HE (2013) Acute skeletal muscle wasting in critical illness. JAMA 310(15):1591\u20131600. https:\/\/doi.org\/10.1001\/jama.2013.278481","journal-title":"JAMA"},{"issue":"6","key":"659_CR2","doi-asserted-by":"publisher","first-page":"406","DOI":"10.5455\/aim.2014.22.406-410","volume":"22","author":"K Koukourikos","year":"2014","unstructured":"Koukourikos K, Tsaloglidou A, Kourkouta L (2014) Muscle atrophy in intensive care unit patients. Acta Inform Med 22(6):406\u2013410. https:\/\/doi.org\/10.5455\/aim.2014.22.406-410","journal-title":"Acta Inform Med"},{"issue":"1","key":"659_CR3","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.clnu.2018.08.037","volume":"38","author":"P Singer","year":"2019","unstructured":"Singer P, Blaser AR, Berger MM, Alhazzani W, Calder PC, Casaer MP, Hiesmayr M, Mayer K, Montejo JC, Pichard C, Preiser JC, van Zanten ARH, Oczkowski S, Szczeklik W, Bischoff SC (2019) ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr 38(1):48\u201379. https:\/\/doi.org\/10.1016\/j.clnu.2018.08.037","journal-title":"Clin Nutr"},{"issue":"23","key":"659_CR4","doi-asserted-by":"publisher","first-page":"4641","DOI":"10.1113\/jphysiol.2010.197632","volume":"588","author":"Z Puthucheary","year":"2010","unstructured":"Puthucheary Z, Montgomery H, Moxham J, Harridge S, Hart N (2010) Structure to function: muscle failure in critically ill patients. J Physiol 588(23):4641\u20134648. https:\/\/doi.org\/10.1113\/jphysiol.2010.197632","journal-title":"J Physiol"},{"issue":"3","key":"659_CR5","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1164\/rccm.200712-1829OC","volume":"178","author":"A Na","year":"2008","unstructured":"Na A, O\u2019Brien JM Jr, Hoffmann SP, Phillips G, Garland A, Finley JC, Almoosa K, Hejal R, Wolf KM, Lemeshow S, Connors AF Jr, Marsh CB (2008) Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med 178(3):261\u2013268. https:\/\/doi.org\/10.1164\/rccm.200712-1829OC","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"659_CR6","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1097\/MCO.0b013e328350767e","volume":"15","author":"M Hiesmayr","year":"2012","unstructured":"Hiesmayr M (2012) Nutrition risk assessment in the ICU. Curr Opin Clin Nutr Metab Care 15(2):174\u2013180. https:\/\/doi.org\/10.1097\/MCO.0b013e328350767e","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"659_CR7","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1186\/s13054-015-0937-2","volume":"19","author":"L Wieske","year":"2015","unstructured":"Wieske L, Dettling-Ihnenfeldt DS, Verhamme C, Nollet F, van Schaik IN, Schultz MJ, Horn J, van der Schaaf M (2015) Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study. Crit Care 19:196. https:\/\/doi.org\/10.1186\/s13054-015-0937-2","journal-title":"Crit Care"},{"issue":"1","key":"659_CR8","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/cc13729","volume":"18","author":"ZA Puthucheary","year":"2014","unstructured":"Puthucheary ZA, Hart N (2014) Skeletal muscle mass and mortality\u2014but what about functional outcome? Crit Care 18(1):110. https:\/\/doi.org\/10.1186\/cc13729","journal-title":"Crit Care"},{"issue":"2","key":"659_CR9","doi-asserted-by":"publisher","first-page":"R12","DOI":"10.1186\/cc13189","volume":"18","author":"PJ Weijs","year":"2014","unstructured":"Weijs PJ, Looijaard WG, Dekker IM, Stapel SN, Girbes AR, Oudemans-van Straaten HM, Beishuizen A (2014) Low skeletal muscle area is a risk factor for mortality in mechanically ventilated critically ill patients. Crit Care 18(2):R12. https:\/\/doi.org\/10.1186\/cc13189","journal-title":"Crit Care"},{"issue":"2","key":"659_CR10","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1097\/MCO.0b013e32835c20b0","volume":"16","author":"E Fiaccadori","year":"2013","unstructured":"Fiaccadori E, Regolisti G, Maggiore U (2013) Specialized nutritional support interventions in critically ill patients on renal replacement therapy. Curr Opin Clin Nutr Metab Care 16(2):217\u2013224. https:\/\/doi.org\/10.1097\/MCO.0b013e32835c20b0","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"4","key":"659_CR11","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s40620-017-0454-2","volume":"31","author":"L Sykes","year":"2018","unstructured":"Sykes L, Nipah R, Kalra P, Green D (2018) A narrative review of the impact of interventions in acute kidney injury. J Nephrol 31(4):523\u2013535. https:\/\/doi.org\/10.1007\/s40620-017-0454-2","journal-title":"J Nephrol"},{"issue":"3","key":"659_CR12","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s40620-017-0452-4","volume":"31","author":"F Fani","year":"2018","unstructured":"Fani F, Regolisti G, Delsante M, Cantaluppi V, Castellano G, Gesualdo L, Villa G, Fiaccadori E (2018) Recent advances in the pathogenetic mechanisms of sepsis-associated acute kidney injury. J Nephrol 31(3):351\u2013359. https:\/\/doi.org\/10.1007\/s40620-017-0452-4","journal-title":"J Nephrol"},{"issue":"2","key":"659_CR13","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1002\/jcsm.12268","volume":"9","author":"F Buckinx","year":"2018","unstructured":"Buckinx F, Landi F, Cesari M, Fielding RA, Visser M, Engelke K, Maggi S, Dennison E, Al-Daghri NM, Allepaerts S, Bauer J, Bautmans I, Brandi ML, Bruyere O, Cederholm T, Cerreta F, Cherubini A, Cooper C, Cruz-Jentoft A, McCloskey E, Dawson-Hughes B, Kaufman JM, Laslop A, Petermans J, Reginster JY, Rizzoli R, Robinson S, Rolland Y, Rueda R, Vellas B, Kanis JA (2018) Pitfalls in the measurement of muscle mass: a need for a reference standard. J Cachexia Sarcopenia Muscle 9(2):269\u2013278. https:\/\/doi.org\/10.1002\/jcsm.12268","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"4","key":"659_CR14","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1097\/CCM.0000000000000821","volume":"43","author":"B Connolly","year":"2015","unstructured":"Connolly B, MacBean V, Crowley C, Lunt A, Moxham J, Rafferty GF, Hart N (2015) Ultrasound for the assessment of peripheral skeletal muscle architecture in critical illness: a systematic review. Crit Care Med 43(4):897\u2013905. https:\/\/doi.org\/10.1097\/CCM.0000000000000821","journal-title":"Crit Care Med"},{"issue":"6","key":"659_CR15","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1016\/j.clnu.2016.09.029","volume":"36","author":"A Sabatino","year":"2017","unstructured":"Sabatino A, Regolisti G, Bozzoli L, Fani F, Antoniotti R, Maggiore U, Fiaccadori E (2017) Reliability of bedside ultrasound for measurement of quadriceps muscle thickness in critically ill patients with acute kidney injury. Clin Nutr 36(6):1710\u20131715. https:\/\/doi.org\/10.1016\/j.clnu.2016.09.029","journal-title":"Clin Nutr"},{"issue":"3","key":"659_CR16","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1016\/j.clnu.2018.05.004","volume":"38","author":"A Sabatino","year":"2019","unstructured":"Sabatino A, Regolisti G, Delsante M, Di Motta T, Cantarelli C, Pioli S, Grassi G, Batini V, Gregorini M, Fiaccadori E (2019) Noninvasive evaluation of muscle mass by ultrasonography of quadriceps femoris muscle in end-stage renal disease patients on hemodialysis. Clin Nutr 38(3):1232\u20131239. https:\/\/doi.org\/10.1016\/j.clnu.2018.05.004","journal-title":"Clin Nutr"},{"key":"659_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/kisup.2012.1","volume":"2","author":"Kidney Disease: Improvig Global Outcomes","year":"2012","unstructured":"Kidney Disease: Improvig Global Outcomes (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2:1\u2013138","journal-title":"Kidney Int Suppl"},{"key":"659_CR18","doi-asserted-by":"publisher","first-page":"h5527","DOI":"10.1136\/bmj.h5527","volume":"351","author":"PM Bossuyt","year":"2015","unstructured":"Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig L, Lijmer JG, Moher D, Rennie D, de Vet HC, Kressel HY, Rifai N, Golub RM, Altman DG, Hooft L, Korevaar DA, Cohen JF, STARD Group (2015) STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ 351:h5527. https:\/\/doi.org\/10.1136\/bmj.h5527","journal-title":"BMJ"},{"issue":"7","key":"659_CR19","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1177\/0148607113501327","volume":"38","author":"M Tillquist","year":"2014","unstructured":"Tillquist M, Kutsogiannis DJ, Wischmeyer PE, Kummerlen C, Leung R, Stollery D, Karvellas CJ, Preiser JC, Bird N, Kozar R, Heyland DK (2014) Bedside ultrasound is a practical and reliable measurement tool for assessing quadriceps muscle layer thickness. JPEN J Parenter Enteral Nutr 38(7):886\u2013890. https:\/\/doi.org\/10.1177\/0148607113501327","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"8476","key":"659_CR20","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","volume":"1","author":"JM Bland","year":"1986","unstructured":"Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet (London, England) 1(8476):307\u2013310","journal-title":"Lancet (London, England)"},{"issue":"6","key":"659_CR21","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1177\/0962280216666667","volume":"27","author":"P Taffe","year":"2018","unstructured":"Taffe P (2018) Effective plots to assess bias and precision in method comparison studies. Stat Methods Med Res 27(6):1650\u20131660. https:\/\/doi.org\/10.1177\/0962280216666667","journal-title":"Stat Methods Med Res"},{"issue":"1","key":"659_CR22","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1177\/1536867X1701700111","volume":"17","author":"P Taff\u00e9","year":"2017","unstructured":"Taff\u00e9 P, Peng M, Stagg V, Williamson T (2017) biasplot: a package to effective plots to assess bias and precision in method comparison studies. Stata J 17(1):208\u2013221","journal-title":"Stata J"},{"issue":"4","key":"659_CR23","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1080\/10543400701329422","volume":"17","author":"JM Bland","year":"2007","unstructured":"Bland JM, Altman DG (2007) Agreement between methods of measurement with multiple observations per individual. J Biopharm Stat 17(4):571\u2013582. https:\/\/doi.org\/10.1080\/10543400701329422","journal-title":"J Biopharm Stat"},{"key":"659_CR24","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1471-2342-12-7","volume":"12","author":"T Thomaes","year":"2012","unstructured":"Thomaes T, Thomis M, Onkelinx S, Coudyzer W, Cornelissen V, Vanhees L (2012) Reliability and validity of the ultrasound technique to measure the rectus femoris muscle diameter in older CAD-patients. BMC Med Imaging 12:7. https:\/\/doi.org\/10.1186\/1471-2342-12-7","journal-title":"BMC Med Imaging"},{"issue":"5","key":"659_CR25","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1136\/thx.2008.103986","volume":"64","author":"JM Seymour","year":"2009","unstructured":"Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, Rafferty G, Polkey MI, Moxham J (2009) Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD. Thorax 64(5):418\u2013423. https:\/\/doi.org\/10.1136\/thx.2008.103986","journal-title":"Thorax"},{"key":"659_CR26","doi-asserted-by":"publisher","first-page":"e392","DOI":"10.6061\/clinics\/2018\/e392","volume":"73","author":"VA Souza","year":"2018","unstructured":"Souza VA, Oliveira D, Cupolilo EN, Miranda CS, Colugnati FAB, Mansur HN, Fernandes N, Bastos MG (2018) Rectus femoris muscle mass evaluation by ultrasound: facilitating sarcopenia diagnosis in pre-dialysis chronic kidney disease stages. Clinics (Sao Paulo, Brazil) 73:e392. https:\/\/doi.org\/10.6061\/clinics\/2018\/e392","journal-title":"Clinics (Sao Paulo, Brazil)"},{"issue":"1","key":"659_CR27","first-page":"103","volume":"16","author":"MG Bemben","year":"2002","unstructured":"Bemben MG (2002) Use of diagnostic ultrasound for assessing muscle size. J Strength Cond Res 16(1):103\u2013108","journal-title":"J Strength Cond Res"},{"issue":"1","key":"659_CR28","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s00421-003-0961-9","volume":"91","author":"ND Reeves","year":"2004","unstructured":"Reeves ND, Maganaris CN, Narici MV (2004) Ultrasonographic assessment of human skeletal muscle size. Eur J Appl Physiol 91(1):116\u2013118. https:\/\/doi.org\/10.1007\/s00421-003-0961-9","journal-title":"Eur J Appl Physiol"},{"issue":"7","key":"659_CR29","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1016\/j.ultrasmedbio.2009.01.004","volume":"35","author":"P Arbeille","year":"2009","unstructured":"Arbeille P, Kerbeci P, Capri A, Dannaud C, Trappe SW, Trappe TA (2009) Quantification of muscle volume by echography: comparison with MRI data on subjects in long-term bed rest. Ultrasound Med Biol 35(7):1092\u20131097. https:\/\/doi.org\/10.1016\/j.ultrasmedbio.2009.01.004","journal-title":"Ultrasound Med Biol"},{"key":"659_CR30","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1186\/1465-9921-13-119","volume":"13","author":"MK Menon","year":"2012","unstructured":"Menon MK, Houchen L, Harrison S, Singh SJ, Morgan MD, Steiner MC (2012) Ultrasound assessment of lower limb muscle mass in response to resistance training in COPD. Respir Res 13:119. https:\/\/doi.org\/10.1186\/1465-9921-13-119","journal-title":"Respir Res"},{"issue":"5","key":"659_CR31","doi-asserted-by":"publisher","first-page":"1151.e9-1151.e1","DOI":"10.1016\/j.jcrc.2015.05.024","volume":"30","author":"Selina M. Parry","year":"2015","unstructured":"Parry SM, El-Ansary D, Cartwright MS, Sarwal A, Berney S, Koopman R, Annoni R, Puthucheary Z, Gordon IR, Morris PE, Denehy L (2015) Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function. J Crit Care 30 (5):1151 e1159\u20131114. https:\/\/doi.org\/10.1016\/j.jcrc.2015.05.024","journal-title":"Journal of Critical Care"},{"issue":"3","key":"659_CR32","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1007\/s00134-015-3668-6","volume":"41","author":"J Segers","year":"2015","unstructured":"Segers J, Hermans G, Charususin N, Fivez T, Vanhorebeek I, Van den Berghe G, Gosselink R (2015) Assessment of quadriceps muscle mass with ultrasound in critically ill patients: intra- and inter-observer agreement and sensitivity. Intensive Care Med 41(3):562\u2013563. https:\/\/doi.org\/10.1007\/s00134-015-3668-6","journal-title":"Intensive Care Med"},{"issue":"6","key":"659_CR33","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1097\/SLA.0000000000001546","volume":"264","author":"N Mueller","year":"2016","unstructured":"Mueller N, Murthy S, Tainter CR, Lee J, Riddell K, Fintelmann FJ, Grabitz SD, Timm FP, Levi B, Kurth T, Eikermann M (2016) Can sarcopenia quantified by ultrasound of the rectus femoris muscle predict adverse outcome of surgical intensive care unit patients as well as frailty? A prospective, observational cohort study. Ann Surg 264(6):1116\u20131124. https:\/\/doi.org\/10.1097\/SLA.0000000000001546","journal-title":"Ann Surg"},{"key":"659_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.11.021","author":"F Landi","year":"2018","unstructured":"Landi F, Camprubi-Robles M, Bear DE, Cederholm T, Malafarina V, Welch AA, Cruz-Jentoft AJ (2018) Muscle loss: the new malnutrition challenge in clinical practice. Clin Nutr. https:\/\/doi.org\/10.1016\/j.clnu.2018.11.021","journal-title":"Clin Nutr"},{"issue":"7","key":"659_CR35","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1164\/rccm.201503-0535OC","volume":"192","author":"NJ Greening","year":"2015","unstructured":"Greening NJ, Harvey-Dunstan TC, Chaplin EJ, Vincent EE, Morgan MD, Singh SJ, Steiner MC (2015) Bedside assessment of quadriceps muscle by ultrasound after admission for acute exacerbations of chronic respiratory disease. Am J Respir Crit Care Med 192(7):810\u2013816. https:\/\/doi.org\/10.1164\/rccm.201503-0535OC","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Journal of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40620-019-00659-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40620-019-00659-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40620-019-00659-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:56:43Z","timestamp":1777564603000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/joneph\/article\/33\/1\/109\/8328591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,15]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["659"],"URL":"https:\/\/doi.org\/10.1007\/s40620-019-00659-2","relation":{},"ISSN":["1121-8428","1724-6059"],"issn-type":[{"value":"1121-8428","type":"print"},{"value":"1724-6059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,15]]},"assertion":[{"value":"3 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All persons who meet authorship criteria are listed as authors, and all authors certify that they have participated sufficiently in the work to take public responsibility for the content, including participation in the concept, design, analysis, writing, or revision of the manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of authorship"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the regional research committee AVEN (authorization 9713 of March 14, 2017), and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}