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Even though there are no pathognomonic morphologic features that can rule out or confirm direct damage by SARS-CoV-2, the latest literature suggests that there may be some association. SARS-CoV-2 infection represents a poor prognostic factor, regardless of pulmonary involvement. We report a challenging case with complex renal biopsy findings suggestive of collapsing glomerulopathy and focal proliferative IgA-dominant glomerulonephritis in a patient affected by active hepatitis C virus (HCV), SARS-CoV-2 infection and personal history of cocaine abuse.<\/jats:p>","DOI":"10.1007\/s40620-022-01351-8","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T07:03:01Z","timestamp":1654498981000},"page":"225-228","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Double glomerulopathies or two-faced janus? 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