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Biofeedback systems have proven to reduce the occurrence of such events, but no conclusive findings can lead\u00a0to wider adoption of these systems. We conducted this systematic review and meta-analysis of randomized clinical trials to establish whether the use of blood volume tracking systems compared to conventional hemodialysis (C-HD) reduces the occurrence of intradialytic hypotension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The PRISMA guidelines were used to carry out this systematic review. Randomized clinical trials that evaluated the incidence of intradialytic hypotension during C-HD and blood volume tracking-HD were searched in the current literature. PROSPERO registration number: CRD42023426328.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety-seven randomized clinical trials were retrieved. Nine studies, including 347 participants and 13,274 HD treatments were considered eligible for this systematic review. The results showed that the use of biofeedback systems reduces the risk of intradialytic hypotension (log odds ratio\u2009=\u20090.63,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03) in hypotension-prone patients (log odds ratio\u2009=\u20090.54,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). When analysis was limited to fluid overloaded or hypertensive patients, it did not show the same effect (log odds ratio\u2009=\u20090.79,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.38). No correlation was found in systolic blood pressure drop during dialysis and in post-dialysis blood pressure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of blood volume tracking systems may be effective in reducing the incidence of intradialytic hypotension and allowing for easier attainment of the patients\u2019 ideal\u00a0dry body weight. New studies to examine the long-term effects of the use of blood volume tracking systems on real hard endpoints are needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s40620-023-01844-0","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T08:02:30Z","timestamp":1711440150000},"page":"897-909","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of blood volume biofeedback hemodialysis and conventional hemodialysis on cardiovascular stability and blood pressure control in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2737-5748","authenticated-orcid":false,"given":"Emanuele","family":"Mambelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Grandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9925-8957","authenticated-orcid":false,"given":"Antonio","family":"Santoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,26]]},"reference":[{"issue":"1 Suppl 1","key":"1844_CR1","doi-asserted-by":"publisher","first-page":"A6","DOI":"10.1053\/j.ajkd.2009.10.009","volume":"55","author":"AJ Collins","year":"2010","unstructured":"Collins AJ, Foley RN, Herzog C et al (2010) Excerpts from the US renal data system 2009 annual data report. 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Fabio Grandi is a biomedical engineer at Medica S.p.A. The Authors declare that their institutions had no role in defining the content of the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article is a review and contains only published data; it does not contain de novo studies with human or animal subjects performed by the author.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}