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Toshio Mochizuki and Hiroshi Kataoka belonged to an endowed department sponsored by Otsuka Pharmaceutical Co., Chugai Pharmaceutical Co., Kyowa Hakko Kirin Co., and JMS Co. The remaining authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Research Ethics Committee of Tokyo Women\u2019s Medical University (approval number, 5118) and conducted in accordance with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All procedures were approved by the research ethics committee of Tokyo Women\u2019s Medical University.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of human and animal rights"}},{"value":"Passive informed consent (in the form of opt-out) was obtained from the patients, and all data were analyzed anonymously.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}