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DC has been national coordinator of the Global aHUS supported by Alexion Pharma. MCM has received speaker\u2019s fees from Alexion Pharma. The remaining authors have nothing to disclose in relation to the present study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The study was approved by the ethics committee Milano Area 2 (No. 335_2023) and was carried out in conformity with the 2013 revision of the Declaration of Helsinki and the code of good clinical practice.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Informed consent was obtained from all patients or from parents for both genetic workup and to use their clinical information for research purposes.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}