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C.Sethna was on an advisory board for Travere Therapeutics. K.R. Tuttle reports support from Eli Lilly; personal fees and other support from Boehringer Ingelheim; personal fees and other support from AstraZeneca; grants, personal fees and other support from Bayer AG; grants, personal fees and other support from Novo Nordisk; grants and other support from Goldfinch Bio; other support from Gilead; and grants from Travere outside the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The NEPTUNE study was approved by the Institutional Review Board (IRB) at each of the 29 participating sites. The NEPTUNE study protocol was reviewed and approved by\u00a0University of Michigan Medical School (IRBMED), Approval Number HUM00158219.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All procedures were approved by the University of Michigan Institutional Review Board.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Written informed consent and\/or assent was obtained from each participant and\/or caregiver before joining the study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}