{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:23:27Z","timestamp":1787066607071,"version":"build-2736575974"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":76,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:00:00Z","timestamp":1763769600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:00:00Z","timestamp":1763769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lack of data regarding pregnancy post-kidney transplantation challenges clinicians who are faced with complex, high-risk cases. Aiming at tackling knowledge gaps and limited cross-cultural data on pregnancy in kidney transplant recipients (KTRs), we compared the methodologies\u00a0and pregnancy outcomes of three registries based in three continents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were gathered from reports and publications of the Pregnancy After Renal Transplantation OUTcomes registry (PARTOUT, Netherlands), the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA), and the Transplant Pregnancy Registry International (TPRI, United States of America and international). We targeted the similarities and differences among the registries to understand methodological variations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The registries utilized distinct approaches regarding data collection which influence data interpretation. PARTOUT conducted a retrospective analysis of all Dutch pregnant KTRs between 1971 and 2017. ANZDATA includes annual surveys on all KTR parenthood events since 1968. TPRI offers international coverage and includes pregnant KTRs voluntarily registered since 1991. Despite methodological differences, preeclampsia, preterm birth and low birth weight were common pregnancy complications, and outcomes were mostly comparable among the\u00a0registries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite differences in case capture, the three registries reported similar pregnancy and newborn outcomes, confirming that pregnancy in KTRs can be successful with careful monitoring across varying populations. Identifying the strengths and weaknesses of each registry can contribute to improved methodologies for global data collection and lower missing data rates. Although managing\u00a0large databases may be challenging, aligning data across countries could lead to meaningful data pooling, while identifying drivers of outcomes across subpopulations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical abstract<\/jats:title>\n                    <jats:p\/>\n                  <\/jats:sec>","DOI":"10.1007\/s40620-025-02451-x","type":"journal-article","created":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T15:25:24Z","timestamp":1763825124000},"page":"2969-2976","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pregnancy after kidney transplantation: global insights based on registry data from three continents"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8996-6347","authenticated-orcid":false,"given":"Styliani","family":"Giapoutzidou","sequence":"first","affiliation":[{"name":"https:\/\/ror.org\/03cv38k47 grid.4494.d 0000 0000 9558 4598 Department of Nephrology University Medical Center Groningen Groningen Netherlands 1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erandi","family":"Hewawasam","sequence":"additional","affiliation":[{"name":"https:\/\/ror.org\/03e3kts03 grid.430453.5 0000 0004 0565 2606 Australia and New Zealand Dialysis and Transplant Registry South Australian Health and Medical Research Institute Adelaide Australia 2"},{"name":"https:\/\/ror.org\/00892tw58 grid.1010.0 0000 0004 1936 7304 Faculty of Health and Medical Sciences University of Adelaide Adelaide Australia 3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margriet E.","family":"Gosselink","sequence":"additional","affiliation":[{"name":"https:\/\/ror.org\/0575yy874 grid.7692.a 0000 0000 9012 6352 Department of Obstetrics and Gynecology University Medical Center Utrecht Utrecht Netherlands 4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Titia Lely","sequence":"additional","affiliation":[{"name":"https:\/\/ror.org\/0575yy874 grid.7692.a 0000 0000 9012 6352 Department of Obstetrics and Gynecology University Medical Center Utrecht Utrecht Netherlands 4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Moritz","sequence":"additional","affiliation":[{"name":"Transplant Pregnancy Registry International Gift of Life Institute Philadelphia PA USA 5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serban","family":"Constantinescu","sequence":"additional","affiliation":[{"name":"Transplant Pregnancy Registry International Gift of Life Institute Philadelphia PA USA 5"},{"name":"https:\/\/ror.org\/00kx1jb78 grid.264727.2 0000 0001 2248 3398 Medicine Lewis Katz School of Medicine at Temple University Philadelphia PA USA 6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Coscia","sequence":"additional","affiliation":[{"name":"Transplant Pregnancy Registry International Gift of Life Institute Philadelphia PA USA 5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpanjali","family":"Jesudason","sequence":"additional","affiliation":[{"name":"https:\/\/ror.org\/03e3kts03 grid.430453.5 0000 0004 0565 2606 Australia and New Zealand Dialysis and Transplant Registry South Australian Health and Medical Research Institute Adelaide Australia 2"},{"name":"https:\/\/ror.org\/00892tw58 grid.1010.0 0000 0004 1936 7304 Faculty of Health and Medical Sciences University of Adelaide Adelaide Australia 3"},{"name":"https:\/\/ror.org\/00carf720 grid.416075.1 0000 0004 0367 1221 Central Northern Adelaide Renal and Transplantation Services Royal Adelaide Hospital Adelaide Australia 7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margriet F. C.","family":"de Jong","sequence":"additional","affiliation":[{"name":"https:\/\/ror.org\/03cv38k47 grid.4494.d 0000 0000 9558 4598 Department of Nephrology University Medical Center Groningen Groningen Netherlands 1"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,11,22]]},"reference":[{"issue":"8","key":"2026020606012921000_CR1","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1097\/tp.0000000000003026","article-title":"Long-term graft survival and graft function following pregnancy in kidney transplant recipients: a systematic review and meta-analysis","volume":"104","author":"van Buren","year":"2019","journal-title":"Transplantation"},{"issue":"4","key":"2026020606012921000_CR2","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.kint.2022.08.007","article-title":"Pregnancy outcomes after kidney transplantation: the challenges of success","volume":"102","author":"Jesudason","year":"2022","journal-title":"Kidney Int"},{"key":"2026020606012921000_CR3","doi-asserted-by":"publisher","DOI":"10.1097\/tp.0000000000005341","article-title":"Pregnancy after solid organ transplantation: review of the evidence and recommendations","author":"Katz-Greenberg","year":"2025","journal-title":"Transplantation"},{"issue":"12","key":"2026020606012921000_CR4","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.1111\/tri.14156","article-title":"Comparison of pregnancy outcomes in Dutch kidney recipients with and without calcineurin inhibitor exposure: a retrospective study","volume":"34","author":"Koenjer","year":"2021","journal-title":"Transplant Int"},{"key":"2026020606012921000_CR5"},{"key":"2026020606012921000_CR6","volume-title":"ANZDATA special report: parenthood survey 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study","volume":"106","author":"van Buren","year":"2022","journal-title":"Transplantation"}],"container-title":["Journal of 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July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors of this manuscript have conflicts of interest to disclose as described by the\n                      Journal of Nephrology\n                      . Erandi Hewawasam is supported by The Hospital Research Foundation 2021 Women\u2019s Health Grant awarded to Shilpanjali Jesudason. TPRI is supported by the Veloxis Pharmaceutical grant.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Since no primary data were generated, ethics approval was not required. Each registry has been approved separately. For PARTOUT, each university medical center in the Netherlands acquired approval by its medical ethics committee (MEC-2016-634, 16-021\/C, G16.014, 2015-2262). Internal analysis of ANZDATA was approved by the Central Adelaide Local Health Network Human Research Ethics Committee (Reference: HREC\/17\/RAH\/408). The TPRI and its associated studies were approved by the Advarra Institutional Review Board Protocol# Pro0000800.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent to participate"}}]}}