{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:26:46Z","timestamp":1790641606584,"version":"4.1.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:00:00Z","timestamp":1648166400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:00:00Z","timestamp":1648166400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Ther"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s40744-022-00438-9","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T06:02:21Z","timestamp":1648188141000},"page":"891-905","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Photobiomodulation Therapy: A New Light in the Treatment of Systemic Sclerosis Skin Ulcers"],"prefix":"10.1007","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4941-8507","authenticated-orcid":false,"given":"Amelia","family":"Spinella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0947-8663","authenticated-orcid":false,"given":"Marco","family":"de Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7339-3234","authenticated-orcid":false,"given":"Claudio","family":"Galluzzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5840-7290","authenticated-orcid":false,"given":"Sofia","family":"Testoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierluca","family":"Macrip\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4671-7982","authenticated-orcid":false,"given":"Federica","family":"Lumetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Parenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Magnani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0454-1093","authenticated-orcid":false,"given":"Gilda","family":"Sandri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6430-800X","authenticated-orcid":false,"given":"Gianluigi","family":"Bajocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0052-5061","authenticated-orcid":false,"given":"Marta","family":"Starnoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6717-5767","authenticated-orcid":false,"given":"Giorgio","family":"De Santis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5426-5133","authenticated-orcid":false,"given":"Carlo","family":"Salvarani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0041-3695","authenticated-orcid":false,"given":"Dilia","family":"Giuggioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,25]]},"reference":[{"issue":"2","key":"438_CR1","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s12016-010-8198-y","volume":"40","author":"E Hachulla","year":"2011","unstructured":"Hachulla E, Launay D. Diagnosis and classification of systemic sclerosis. Clin Rev Allergy Immunol. 2011;40(2):78\u201383. https:\/\/doi.org\/10.1007\/s12016-010-8198-y (PMID: 20143182).","journal-title":"Clin Rev Allergy Immunol"},{"key":"438_CR2","doi-asserted-by":"crossref","unstructured":"van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, et al. 2013 Classification criteria for systemic sclerosis: an American College of Rheumatology\/European League against Rheumatism collaborative initiative. Arthritis Rheumatol. 2013;65(11):2737\u201347.","DOI":"10.1002\/art.38098"},{"issue":"10","key":"438_CR3","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1016\/j.autrev.2014.08.029","volume":"13","author":"C Ferri","year":"2014","unstructured":"Ferri C, Sebastiani M, Lo Monaco A, Iudici M, Giuggioli D, Furini F, et al. Systemic sclerosis evolution of disease pathomorphosis and survival. Our experience on Italian patients\u2019 population and review of the literature. Autoimmun Rev. 2014;13(10):1026\u201334.","journal-title":"Autoimmun Rev"},{"issue":"Suppl 3","key":"438_CR4","first-page":"19","volume":"48","author":"V Steen","year":"2009","unstructured":"Steen V, Denton CP, Pope JE, Matucci-Cerinic M. Digital ulcers: overt vascular disease in systemic sclerosis. Rheumatology. 2009;48(Suppl 3):19\u201324.","journal-title":"Rheumatology"},{"key":"438_CR5","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1093\/rheumatology\/keq097","volume":"49","author":"L Amanzi","year":"2010","unstructured":"Amanzi L, Braschi F, Fiori G, Galluccio F, Miniati I, Guiducci S, et al. Digital ulcers in scleroderma: staging, characteristics and sub-setting through observation of 1614 digital lesions. Rheumatology (Oxford). 2010;49:1374\u201382.","journal-title":"Rheumatology (Oxford)"},{"key":"438_CR6","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1002\/acr.20673","volume":"64","author":"D Giuggioli","year":"2011","unstructured":"Giuggioli D, Manfredi A, Colaci M, Lumetti F, Ferri C. Scleroderma digital ulcers complicated by infection with fecal pathogens. Arthritis Care Res (Hoboken). 2011;64:295\u20137.","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"438_CR7","first-page":"5","volume":"33","author":"D Giuggioli","year":"2015","unstructured":"Giuggioli D, Manfredi A, Vacchi C, Sebastiani M, Spinella A, Ferri C. Procedural pain management in the treatment of scleroderma digital ulcers. Clin Exp Rheumatol. 2015;33:5\u201310.","journal-title":"Clin Exp Rheumatol"},{"key":"438_CR8","doi-asserted-by":"publisher","first-page":"1770","DOI":"10.1136\/annrheumdis-2015-208121","volume":"75","author":"M Matucci-Cerinic","year":"2016","unstructured":"Matucci-Cerinic M, Krieg T, Guillevin L, Schwierin B, Rosenberg D, Cornelisse P, et al. Elucidating the burden of recurrent and chronic digital ulcers in systemic sclerosis: long-term results from the DUO Registry. Ann Rheum Dis. 2016;75:1770\u20136.","journal-title":"Ann Rheum Dis"},{"key":"438_CR9","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.autrev.2017.11.020","volume":"17","author":"D Giuggioli","year":"2018","unstructured":"Giuggioli D, Manfredi A, Lumetti F, Colaci M, Ferri C. Scleroderma skin ulcers definition, classification and treatment strategies our experience and review of the literature. Autoimmun Rev. 2018;17:155\u201364.","journal-title":"Autoimmun Rev"},{"key":"438_CR10","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1046\/j.1524-475X.11.s2.1.x","volume":"11","author":"GS Schultz","year":"2003","unstructured":"Schultz GS, Sibbald RG, Falanga V, Ayello EA, Dowsett C, Harding K, et al. Wound bed preparation: a systematic approach to wound management. Wound Repair Regen. 2003;11:S1-28.","journal-title":"Wound Repair Regen"},{"key":"438_CR11","doi-asserted-by":"crossref","unstructured":"Kowal-Bielecka O, Landew\u00e9 R, Avouac J, Chwiesko S, Miniati I, Czirjak L, et al. EULAR recommendations for the treatment of systemic sclerosis: a report from the EULAR Scleroderma Trials and Research Group (EUSTAR). Ann Rheum Dis. 2009;68:620\u20138.","DOI":"10.1136\/ard.2008.096677"},{"issue":"4","key":"438_CR12","doi-asserted-by":"publisher","first-page":"300060519882176","DOI":"10.1177\/0300060519882176","volume":"48","author":"D Giuggioli","year":"2020","unstructured":"Giuggioli D, Lumetti F, Spinella A, Cocchiara E, Sighinolfi G, Citriniti G, et al. Use of neem oil and Hypericum perforatum for treatment of calcinosis-related skin ulcers in systemic sclerosis. J Int Med Res. 2020;48(4):300060519882176.","journal-title":"J Int Med Res"},{"issue":"5","key":"438_CR13","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1007\/s00266-020-01848-2","volume":"44","author":"M Pignatti","year":"2020","unstructured":"Pignatti M, Spinella A, Cocchiara E, Boscaini G, Lusetti IL, Citriniti G, et al. Autologous fat grafting for the oral and digital complications of systemic sclerosis: results of a prospective study. Aesthet Plast Surg. 2020;44(5):1820\u201332.","journal-title":"Aesthet Plast Surg"},{"key":"438_CR14","doi-asserted-by":"crossref","unstructured":"Pignatti M, Spinella A, Cocchiara E, Boscaini G, Lusetti IL, Citriniti G, et al. Invited response on: Comments on \u201cAutologous fat grafting for the oral and digital complications of systemic sclerosis: results of a prospective study.\u201d Aesthet Plast Surg. 2021;45(3):1344\u20135.","DOI":"10.1007\/s00266-020-02024-2"},{"issue":"1","key":"438_CR15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1080\/23320885.2021.1881521","volume":"8","author":"D Giuggioli","year":"2021","unstructured":"Giuggioli D, Spinella A, Cocchiara E, de Pinto M, Pinelli M, Parenti L, et al. Autologous fat grafting in the treatment of a scleroderma stump-skin ulcer: a case report. Case reports. Plast Surg Hand Surg. 2021;8(1):18\u201322.","journal-title":"Plast Surg Hand Surg"},{"issue":"1","key":"438_CR16","doi-asserted-by":"publisher","first-page":"107","DOI":"10.2217\/rme.15.82","volume":"11","author":"DP Kuffler","year":"2016","unstructured":"Kuffler DP. Photobiomodulation in promoting wound healing: a review. Regen Med. 2016;11(1):107\u201322. https:\/\/doi.org\/10.2217\/rme.15.82 (Epub 2015 Dec 18 PMID: 26681143).","journal-title":"Regen Med"},{"issue":"6","key":"438_CR17","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1002\/jbio.201500191","volume":"9","author":"R Cicchi","year":"2016","unstructured":"Cicchi R, Rossi F, Alfieri D, Bacci S, Tatini F, De Siena G. Observation of an improved healing process in superficial skin wounds after irradiation with a blue-LED haemostatic device. J Biophotonics. 2016;9(6):645\u201355.","journal-title":"J Biophotonics"},{"key":"438_CR18","doi-asserted-by":"crossref","unstructured":"Mosca RC, Ong AA, Albasha O, Bass K, Arany P. Photobiomodulation therapy for wound care: a potent, noninvasive photoceutical approach. Adv Skin Wound Care. 2019;32(4):157\u201367.","DOI":"10.1097\/01.ASW.0000553600.97572.d2"},{"issue":"2","key":"438_CR19","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1111\/phpp.12527","volume":"36","author":"G Magni","year":"2020","unstructured":"Magni G, Tatini F, Bacci S, Paroli G, De Siena G, Cicchi R, et al. Blue LED light modulates inflammatory infiltrate and improves the healing of superficial wounds. Photodermatol Photoimmunol Photomed. 2020;36(2):166\u20138.","journal-title":"Photodermatol Photoimmunol Photomed"},{"issue":"12","key":"438_CR20","doi-asserted-by":"publisher","first-page":"573","DOI":"10.3390\/biomedicines8120573","volume":"8","author":"G Magni","year":"2020","unstructured":"Magni G, Banchelli M, Cherchi F, Coppi E, Fraccalvieri M, Rossi M, et al. Experimental study on blue light interaction with human keloid-derived fibroblasts. Biomedicines. 2020;8(12):573.","journal-title":"Biomedicines"},{"issue":"1","key":"438_CR21","doi-asserted-by":"publisher","first-page":"41","DOI":"10.3390\/biomedicines9010041","volume":"9","author":"F Rossi","year":"2021","unstructured":"Rossi F, Magni G, Tatini F, Banchelli M, Cherchi F, Rossi M, et al. Photobiomodulation of human fibroblasts and keratinocytes with blue light: implications in wound healing. Biomedicines. 2021;9(1):41.","journal-title":"Biomedicines"},{"issue":"9","key":"438_CR22","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1007\/s10103-019-02813-5","volume":"34","author":"PTR de Abreu","year":"2019","unstructured":"de Abreu PTR, de Arruda JAA, Mesquita RA, Abreu LG, Diniz IMA, Silva TA. Photobiomodulation effects on keratinocytes cultured in vitro: a critical review. Lasers Med Sci. 2019;34(9):1725\u201334.","journal-title":"Lasers Med Sci"},{"issue":"2019","key":"438_CR23","first-page":"6320515","volume":"28","author":"A Lopez","year":"2019","unstructured":"Lopez A, Brundage C. Wound photobiomodulation treatment outcomes in animal models. J Vet Med. 2019;28(2019):6320515.","journal-title":"J Vet Med"},{"key":"438_CR24","doi-asserted-by":"crossref","unstructured":"Leaper DJ, Schultz G, Carville K, Fletcher J, Swanson T, Drake R. Extending the TIME concept: what have we learned in the past 10 years? Int Wound J. 2012;9(Suppl 2):1\u201319.","DOI":"10.1111\/j.1742-481X.2012.01097.x"},{"key":"438_CR25","doi-asserted-by":"crossref","unstructured":"Denton CP, Hughes M, Gak N, Vila J, Buch MH, Chakravarty K, et al. BSR and BHPR Standards, Guidelines and Audit Working Group. BSR and BHPR guideline for the treatment of systemic sclerosis. Rheumatology (Oxford). 2016;55:1906\u201310.","DOI":"10.1093\/rheumatology\/kew224"},{"issue":"6","key":"438_CR26","first-page":"709","volume":"156","author":"V Dini","year":"2021","unstructured":"Dini V, Romanelli M, Oranges T, Davini G, Janowska A. Blue light emission in the management of hard-to-heal wounds. Ital J Dermatol Venerol. 2021;156(6):709\u201313.","journal-title":"Ital J Dermatol Venerol"},{"key":"438_CR27","doi-asserted-by":"crossref","unstructured":"Fraccalvieri M, Amadeo G, Bortolotti P, Ciliberti M, Garrubba A, Mosti G et al. Effectiveness of blue light photobiomodulation therapy in the treatment of chronic wounds. Results of the Blue Light for Ulcer Reduction (B.L.U.R.) Study. Ital J Dermatol Venerol. 2021.","DOI":"10.23736\/S2784-8671.21.07067-5"},{"key":"438_CR28","doi-asserted-by":"publisher","first-page":"v67","DOI":"10.1093\/rheumatology\/kex200","volume":"56","author":"F Galluccio","year":"2017","unstructured":"Galluccio F, Allanore Y, Czirjak L, Furst DE, Khanna D, Matucci-Cerinic M. Points to consider for skin ulcers in systemic sclerosis. Rheumatology (Oxford). 2017;56:v67-71.","journal-title":"Rheumatology (Oxford)"},{"key":"438_CR29","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1111\/1346-8138.13275","volume":"43","author":"M Fujimoto","year":"2016","unstructured":"Fujimoto M, Asano Y, Ishii T, Ogawa F, Kawakami T, Kodera M, et al. The wound\/burn guidelines\u20144: guidelines for the management of skin ulcers associated with connective tissue disease\/vasculitis. J Dermatol. 2016;43:729\u201357.","journal-title":"J Dermatol"},{"issue":"5","key":"438_CR30","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.clindermatol.2016.05.002","volume":"34","author":"A Grzybowski","year":"2016","unstructured":"Grzybowski A, Sak J, Pawlikowski J. A brief report on the history of phototherapy. Clin Dermatol. 2016;34(5):532\u20137.","journal-title":"Clin Dermatol"},{"issue":"4","key":"438_CR31","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1089\/pho.2015.9848","volume":"33","author":"JJ Anders","year":"2015","unstructured":"Anders JJ, Lanzafame RJ, Arany PR. Low-level light\/laser therapy versus photobiomodulation therapy. Photomed Laser Surg. 2015;33(4):183\u20134.","journal-title":"Photomed Laser Surg"},{"issue":"1","key":"438_CR32","doi-asserted-by":"publisher","first-page":"9885","DOI":"10.1038\/s41598-018-28131-4","volume":"8","author":"Y Zhu","year":"2018","unstructured":"Zhu Y, Xu G, Yuan J, Jo J, Gandikota G, Demirci H, et al. Light emitting diodes based photoacoustic imaging and potential clinical applications. Sci Rep. 2018;8(1):9885.","journal-title":"Sci Rep"},{"key":"438_CR33","doi-asserted-by":"crossref","unstructured":"Hamblin MR, de Sousa MVP, Agrawal T. Handbook of low-level laser therapy. New York: Pan Stanford; 2016.","DOI":"10.1201\/9781315364827"},{"key":"438_CR34","doi-asserted-by":"crossref","unstructured":"Martin P. Wound healing\u2014aiming for perfect skin regeneration. Science. 1997;276(5309):75\u201381.","DOI":"10.1126\/science.276.5309.75"},{"key":"438_CR35","doi-asserted-by":"crossref","first-page":"153473462110041","DOI":"10.1177\/15347346211004186","volume":"11","author":"HKR Nair","year":"2021","unstructured":"Nair HKR, Chong SSY, Selvaraj DDJ. Photobiomodulation as an adjunct therapy in wound healing. Int J Low Extreme Wounds. 2021;11:15347346211004186.","journal-title":"Int J Low Extreme Wounds"},{"issue":"1","key":"438_CR36","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3390\/photonics9010010","volume":"9","author":"RC Mosca","year":"2022","unstructured":"Mosca RC, Santos SN, Nogueira GEC, Pereira DL, Costa FC, Pereira JX, et al. The efficacy of photobiomodulation therapy in improving tissue resilience and healing of radiation skin damage. Photonics. 2022;9(1):10.","journal-title":"Photonics"},{"issue":"12","key":"438_CR37","doi-asserted-by":"publisher","first-page":"837","DOI":"10.12968\/jowc.2018.27.12.837","volume":"27","author":"AG Maiya","year":"2018","unstructured":"Maiya AG, Kumar AS, Hazari A, Jadhav R, Ramachandra L, Hande HM, Rajgopal SK, et al. Photobiomodulation therapy in neuroischaemic diabetic foot ulcers: a novel method of limb salvage. J Wound Care. 2018;27(12):837\u201342.","journal-title":"J Wound Care"},{"issue":"1","key":"438_CR38","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1186\/s13287-020-01967-2","volume":"11","author":"H Ahmadi","year":"2020","unstructured":"Ahmadi H, Amini A, FadaeiFathabady F, Mostafavinia A, Zare F, Ebrahimpour-Malekshah R, et al. Transplantation of photobiomodulation-preconditioned diabetic stem cells accelerates ischemic wound healing in diabetic rats. Stem Cell Res Ther. 2020;11(1):494.","journal-title":"Stem Cell Res Ther"},{"issue":"3","key":"438_CR39","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1080\/09546634.2018.1484875","volume":"30","author":"M Hughes","year":"2019","unstructured":"Hughes M, Moore T, Manning J, Wilkinson J, Watson S, Samraj P, et al. A feasibility study of a novel low-level light therapy for digital ulcers in systemic sclerosis. J Dermatol Treat. 2019;30(3):251\u20137.","journal-title":"J Dermatol Treat"},{"issue":"8","key":"438_CR40","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1039\/C9PP00089E","volume":"18","author":"H Serrate","year":"2019","unstructured":"Serrate H, Heiskanen V, Palin WM, Cooper PR, Milward MR, Hadis M, et al. Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light. Photochem Photobiol Sci. 2019;18(8):1877\u2013909.","journal-title":"Photochem Photobiol Sci"},{"issue":"9","key":"438_CR41","doi-asserted-by":"publisher","first-page":"2265","DOI":"10.1007\/s10103-015-1799-1","volume":"30","author":"DS Masson-Meyers","year":"2015","unstructured":"Masson-Meyers DS, Bumah VV, Biener G, Raicu V, Enwemeka CS. The relative antimicrobial effect of blue 405 nm LED and blue 405 nm laser on methicillin-resistant Staphylococcus aureus in vitro. Lasers Med Sci. 2015;30(9):2265\u201371.","journal-title":"Lasers Med Sci"},{"key":"438_CR42","doi-asserted-by":"crossref","unstructured":"Niu T, Tian Y, Cai Q, Ren Q, Wei L. Red light combined with blue light irradiation regulates proliferation and apoptosis in skin keratinocytes in combination with low concentrations of curcumin. PLoS One. 2015;10(9).","DOI":"10.1371\/journal.pone.0138754"},{"issue":"2","key":"438_CR43","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/php.12864","volume":"94","author":"MR Hamblin","year":"2018","unstructured":"Hamblin MR. Mechanisms and mitochondrial redox signaling in photobiomodulation. Photochem Photobiol. 2018;94(2):199\u2013212.","journal-title":"Photochem Photobiol"},{"key":"438_CR44","unstructured":"Marchelli M, Perniciaro G, Granara D, et al. Photobiomodulation with blue light in non-healing wounds: case series evaluation. Wounds Int. 2019;10(3):63\u20136."},{"key":"438_CR45","doi-asserted-by":"crossref","unstructured":"de Oliveira AB, Ferrisse TM, Salom\u00e3o KB, Miranda ML, Bufalino A, Brighenti FL. Photobiomodulation in the treatment of xerostomia associated with hyposalivation in a pediatric patient with systemic scleroderma. Autops Case Rep. 2020;11:e2020220.","DOI":"10.4322\/acr.2020.220"},{"key":"438_CR46","doi-asserted-by":"crossref","unstructured":"Castellano-Pellicena I, Uzunbajakava NE, Mignon C, Raafs B, Botchkarev VA, Thornton MJ. Does blue light restore human epidermal barrier function via activation of opsin during cutaneous wound healing? Lasers Surg Med. 2019;51(4):370\u201382.","DOI":"10.1002\/lsm.23015"},{"issue":"5","key":"438_CR47","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1111\/phpp.12578","volume":"36","author":"S Suh","year":"2020","unstructured":"Suh S, Choi EH, Atanaskova MN. The expression of opsins in the human skin and its implications for photobiomodulation: a systematic review. Photodermatol Photoimmunol Photomed. 2020;36(5):329\u201338.","journal-title":"Photodermatol Photoimmunol Photomed"}],"container-title":["Rheumatology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40744-022-00438-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40744-022-00438-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40744-022-00438-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T04:14:03Z","timestamp":1653365643000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40744-022-00438-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,25]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["438"],"URL":"https:\/\/doi.org\/10.1007\/s40744-022-00438-9","relation":{},"ISSN":["2198-6576","2198-6584"],"issn-type":[{"value":"2198-6576","type":"print"},{"value":"2198-6584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,25]]},"assertion":[{"value":"28 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}