{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T19:25:46Z","timestamp":1784057146161,"version":"3.55.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Kyowa Kirin Co., Ltd."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Rheumatol Ther"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1007\/s40744-025-00745-x","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T15:49:04Z","timestamp":1738770544000},"page":"297-314","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Factors Influencing Treatment Satisfaction and Recognition Gaps Between Physicians and Patients with Systemic Sclerosis"],"prefix":"10.1007","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2523-2938","authenticated-orcid":false,"given":"Yoshihito","family":"Shima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5781-9485","authenticated-orcid":false,"given":"Mona","family":"Uchida-Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8286-0669","authenticated-orcid":false,"given":"Sei-ichiro","family":"Motegi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruka","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshito","family":"Ohya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0300-4917","authenticated-orcid":false,"given":"Yasumasa","family":"Kanai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"745_CR1","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1016\/S0140-6736(17)30933-9","volume":"390","author":"CP Denton","year":"2017","unstructured":"Denton CP, Khanna D. Systemic sclerosis. Lancet. 2017;390:1685\u201399.","journal-title":"Lancet"},{"key":"745_CR2","first-page":"1567","volume":"41","author":"M Di Battista","year":"2023","unstructured":"Di Battista M, Lepri G, Codullo V, et al. Systemic sclerosis: one year in review 2023. Clin Exp Rheumatol. 2023;41:1567\u201374.","journal-title":"Clin Exp Rheumatol"},{"issue":"Suppl 1","key":"745_CR3","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2018-000782","volume":"4","author":"V Smith","year":"2018","unstructured":"Smith V, Scir\u00e8 CA, Talarico R, et al. Systemic sclerosis: state of the art on clinical practice guidelines. RMD Open. 2018;4(Suppl 1):e000782.","journal-title":"RMD Open"},{"key":"745_CR4","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2017-000232","volume":"4","author":"S Arat","year":"2017","unstructured":"Arat S, Lenaerts JL, De Langhe E, et al. Illness representations of systemic lupus erythematosus and systemic sclerosis: a comparison of patients, their rheumatologists and their general practitioners. Lupus Sci Med. 2017;4:e000232.","journal-title":"Lupus Sci Med"},{"key":"745_CR5","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1186\/s12891-017-1603-4","volume":"18","author":"L Mouthon","year":"2017","unstructured":"Mouthon L, Alami S, Boisard AS, Chaigne B, Hachulla E, Poiraudeau S. Patients\u2019 views and needs about systemic sclerosis and its management: a qualitative interview study. BMC Musculoskelet Disord. 2017;18:230.","journal-title":"BMC Musculoskelet Disord"},{"key":"745_CR6","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1007\/s12016-017-8636-1","volume":"55","author":"M Cossu","year":"2018","unstructured":"Cossu M, Beretta L, Mosterman P, de Hair MJH, Radstake TRDJ. Unmet needs in systemic sclerosis understanding and treatment: the knowledge gaps from a scientist\u2019s, clinician\u2019s, and patient\u2019s perspective. Clin Rev Allergy Immunol. 2018;55:312\u201331.","journal-title":"Clin Rev Allergy Immunol"},{"key":"745_CR7","unstructured":"Denton C, Laird B, Moros L, Luis Luna Flores J. Divided by a common language: challenges in physician-patient communication limit patient understanding and support in systemic sclerosis with interstitial lung disease (SSc-ILD) [abstract]. Arthritis Rheumatol. 2017;69(suppl10). https:\/\/acrabstracts.org\/abstract\/divided-by-a-common-language-challenges-in-physician-patient-communication-limit-patient-understanding-and-support-in-systemic-sclerosis-with-interstitial-lung-disease-ssc-ild\/. Accessed Jan 31, 2025."},{"key":"745_CR8","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1007\/s10067-020-05371-2","volume":"40","author":"C Denton","year":"2021","unstructured":"Denton C, Laird B, Moros L, Luis Luna Flores J. Things left unsaid: important topics that are not discussed between patients with systemic sclerosis, their carers and their healthcare professionals - a discourse analysis. Clin Rheumatol. 2021;40:1399\u20131407.","journal-title":"Clin Rheumatol"},{"key":"745_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2021.104088","volume":"50","author":"B Thoreau","year":"2021","unstructured":"Thoreau B, Chaigne B, Renaud A, Mouthon L. Treatment of systemic sclerosis. Presse Med. 2021;50:104088.","journal-title":"Presse Med"},{"key":"745_CR10","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1093\/rheumatology\/keq310","volume":"50","author":"M Bassel","year":"2011","unstructured":"Bassel M, Hudson M, Taillefer SS, Schieir O, Baron M, Thombs BD. Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey. Rheumatology (Oxford). 2011;50:762\u20137.","journal-title":"Rheumatology (Oxford)"},{"key":"745_CR11","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1002\/acr.24567","volume":"74","author":"S Harb","year":"2022","unstructured":"Harb S, Pel\u00e1ez S, Carrier ME, et al. Barriers and facilitators to physical activity for people with scleroderma: a scleroderma patient-centered intervention network cohort study. Arthritis Care Res (Hoboken). 2022;74:1300\u201310.","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"745_CR12","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1002\/art.41246","volume":"72","author":"V Nagaraja","year":"2020","unstructured":"Nagaraja V, Matucci-Cerinic M, Furst DE, et al. Current and future outlook on disease modification and defining low disease activity in systemic sclerosis. Arthritis Rheumatol. 2020;72:1049\u201358.","journal-title":"Arthritis Rheumatol"},{"key":"745_CR13","unstructured":"Ministry of Education, Culture, Sports, Science and Technology. Ethical guidelines for medical and biological research involving human subjects. 2015. https:\/\/www.mhlw.go.jp\/file\/06-Seisakujouhou-10600000-Daijinkanboukouseikagakuka\/0000080278.pdf Accessed Aug 29, 2024."},{"key":"745_CR14","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1007\/s40674-016-0052-9","volume":"2","author":"A Young","year":"2016","unstructured":"Young A, Namas R, Dodge C, Khanna D. Hand impairment in systemic sclerosis: various manifestations and currently available treatment. Curr Treatm Opt Rheumatol. 2016;2:252\u201369.","journal-title":"Curr Treatm Opt Rheumatol"},{"key":"745_CR15","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.semarthrit.2019.11.003","volume":"50","author":"RD Sandler","year":"2020","unstructured":"Sandler RD, Matucci-Cerinic M, Hughes M. Musculoskeletal hand involvement in systemic sclerosis. Semin Arthritis Rheum. 2020;50:329\u201334.","journal-title":"Semin Arthritis Rheum"},{"key":"745_CR16","doi-asserted-by":"publisher","first-page":"doy136","DOI":"10.1093\/dote\/doy136","volume":"32","author":"JL Horsley-Silva","year":"2019","unstructured":"Horsley-Silva JL, Umar SB, Vela MF, et al. The impact of gastroesophageal reflux disease symptoms in scleroderma: effects on sleep quality. Dis Esophagus. 2019;32:doy136.","journal-title":"Dis Esophagus"},{"key":"745_CR17","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1159\/000490526","volume":"12","author":"J Shah","year":"2018","unstructured":"Shah J, Shahidullah A. Chronic intestinal pseudo-obstruction in systemic sclerosis: an uncommon presentation. Case Rep Gastroenterol. 2018;12:373\u20138.","journal-title":"Case Rep Gastroenterol"},{"key":"745_CR18","doi-asserted-by":"publisher","first-page":"530","DOI":"10.3906\/sag-2005-314","volume":"51","author":"H Yakut","year":"2021","unstructured":"Yakut H, \u00d6zalevli S, Birlik AM. Fatigue and its relationship with disease-related factors in patients with systemic sclerosis: A cross-sectional study. Turk J Med Sci. 2021;51:530\u20139.","journal-title":"Turk J Med Sci"},{"key":"745_CR19","doi-asserted-by":"publisher","first-page":"117954842091328","DOI":"10.1177\/1179548420913281","volume":"14","author":"TJ Cheema","year":"2020","unstructured":"Cheema TJ, Young M, Rabold E, Barbieri AN, Baldwin N, Steen VD. Patient and physician perspectives on systemic sclerosis-associated interstitial lung disease. Clin Med Insights Circ Respir Pulm Med. 2020;14:1179548420913281.","journal-title":"Clin Med Insights Circ Respir Pulm Med"},{"key":"745_CR20","doi-asserted-by":"publisher","first-page":"792","DOI":"10.3899\/jrheum.131251","volume":"41","author":"LA Saketkoo","year":"2014","unstructured":"Saketkoo LA, Mittoo S, Frankel S, et al. OMERACT Connective Tissue Disease-Interstitial Lung Diseases Working Group. Reconciling healthcare professional and patient perspectives in the development of disease activity and response criteria in connective tissue disease-related interstitial lung diseases. J Rheumatol. 2014;41:792\u20138.","journal-title":"J Rheumatol"},{"issue":"11","key":"745_CR21","doi-asserted-by":"publisher","first-page":"2956","DOI":"10.1093\/rheumatology\/keae394","volume":"63","author":"CP Denton","year":"2024","unstructured":"Denton CP, De Lorenzis E, Roblin E, et al. The 2024 British Society for Rheumatology guideline for management of systemic sclerosis. Rheumatology (Oxford). 2024;63(11):2956\u201375.","journal-title":"Rheumatology (Oxford)"},{"key":"745_CR22","first-page":"709","volume":"26","author":"A Pakozdi","year":"2008","unstructured":"Pakozdi A, Howell K, Wilson H, et al. Inhaled iloprost for the treatment of Raynaud\u2019s phenomenon. Clin Exp Rheumatol. 2008;26:709.","journal-title":"Clin Exp Rheumatol"},{"issue":"2 Suppl 76","key":"745_CR23","first-page":"71","volume":"31","author":"L Guillevin","year":"2013","unstructured":"Guillevin L, Hunsche E, Denton CP, et al. DUO Registry Group. Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry. Clin Exp Rheumatol. 2013;31(2 Suppl 76):71\u201380.","journal-title":"Clin Exp Rheumatol"},{"key":"745_CR24","doi-asserted-by":"publisher","first-page":"221","DOI":"10.5114\/reum.2019.87619","volume":"57","author":"P Sobolewski","year":"2019","unstructured":"Sobolewski P, Ma\u015bli\u0144ska M, Wieczorek M, et al. Systemic sclerosis - multidisciplinary disease: clinical features and treatment. Reumatologia. 2019;57:221\u201333.","journal-title":"Reumatologia"},{"key":"745_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2019.101428","volume":"33","author":"S Bellando-Randone","year":"2019","unstructured":"Bellando-Randone S, Matucci-Cerinic M. Very early systemic sclerosis. Best Pract Res Clin Rheumatol. 2019;33:101428.","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"745_CR26","doi-asserted-by":"publisher","first-page":"3380","DOI":"10.1093\/rheumatology\/keaa127","volume":"59","author":"P Moinzadeh","year":"2020","unstructured":"Moinzadeh P, Kuhr K, Siegert E, et al. Older age onset of systemic sclerosis - accelerated disease progression in all disease subsets. Rheumatology (Oxford). 2020;59:3380\u20139.","journal-title":"Rheumatology (Oxford)"}],"container-title":["Rheumatology and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40744-025-00745-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40744-025-00745-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40744-025-00745-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T20:03:02Z","timestamp":1742328182000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40744-025-00745-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,5]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["745"],"URL":"https:\/\/doi.org\/10.1007\/s40744-025-00745-x","relation":{},"ISSN":["2198-6576","2198-6584"],"issn-type":[{"value":"2198-6576","type":"print"},{"value":"2198-6584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,5]]},"assertion":[{"value":"23 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Yoshihito Shima received grants or contracts from Kobayashi Pharmaceutical Co., Ltd, payment and honoraria for lectures and presentations from Asahi Kasei Pharma Corporation, Chugai Pharmaceutical Co., Ltd, and GSK plc. Sei-ichiro Motegi received grants or contracts from Taiho Pharmaceutical Co., Ltd, Sun Pharma Japan Ltd, Novartis Parma K.K., Kaken Pharmaceutical Co., Ltd, Eli Lilly Japan K.K and Maruho Co., Ltd., and honoraria for lectures and presentations from Janssen Pharmaceutical K.K., Eli Lilly Japan K.K, AbbVie G.K., Sanofi K.K., Daiichi Sankyo Co., Ltd., Leo Pharma, Kyowa Kirin, Co., Ltd., Nobelpharma Co., Ltd., Maruho Co., Ltd., Tori Pharmaceutical Co. Ltd., Kaken Pharmaceutical Co., Ltd, Eisai Co., Ltd., Taiho Pharmaceutical Co. Ltd., Otsuka Pharmaceutical Co., Ltd., Bristol-Myers Squibb K.K., and Sato Yakuhin Kogyo Co. Ltd. Mona Uchida-Yamada, Taku Shimada, Haruka Ishii, and Yasumasa Kanai are employees of Kyowa Kirin Co., Ltd. Mona Uchida-Yamada, Taku Shimada, Haruka Ishii, and Yoshito Ohya own stock in Kyowa Kirin Co., Ltd.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"All respondents gave informed consent before participation. All personnel involved in this study adhered to the Declaration of Helsinki and the Ethical Guidelines for Medical and Biological Research Involving Human Subjects. The Research Ethical Review Committee of Kyowa Kirin Co., Ltd. approved (approval number: EC_0105) this study, which was registered under the clinical trial registration number UMIN000050368.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}