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Tedeschi reports consulting fees from Amgen, Avalo Therapeutics, Fresenius Kabi, Merck, and Novartis, as well as research grant support from Alexion. Daniel H Solomon receives salary support from research contracts to Brigham and Women\u2019s Hospital from Amgen, CorEvitas, and Janssen. He receives royalties from UpToDate on chapters unrelated to this paper. He also holds stock options in GreenCape Health, a digital health company. Zeynep S Tuzun, Leah Santacroce, Hilde S \u00d8rbo, and Sho Fukui declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study was reviewed and approved by the Partners Healthcare Human Subjects Committee (#2021-P000790). All patients gave written informed consent to participate in research with the express understanding that results would be published. The study was conducted in accordance with the Helsinki Declaration of 1964 and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}