{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:54:09Z","timestamp":1759938849932,"version":"3.41.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T00:00:00Z","timestamp":1533600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drug Saf - Case Rep"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s40800-018-0090-3","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T08:28:45Z","timestamp":1533630525000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Metoclopramide: A Safe Alternative to Domperidone? A Case Report on Severe Cardiac Adverse Effects in an Older Patient"],"prefix":"10.1007","volume":"5","author":[{"given":"Laura C.","family":"Sijtsma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina J. P. W.","family":"Keijsers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ang\u00e8le P. M.","family":"Kerckhoffs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willem R. P.","family":"Agema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet E. M.","family":"Bootsma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,8,7]]},"reference":[{"key":"90_CR1","unstructured":"GIP database, Health care institute, the Netherlands. Available at: https:\/\/www.gipdatabank.nl\/ . Accessed Aug 2018."},{"key":"90_CR2","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1046\/j.1365-2125.2003.01875.x","volume":"57","author":"PA Routledge","year":"2014","unstructured":"Routledge PA, O\u2019Mahony MS, Woodhouse KW. Adverse drug reactions in elderly patients. Br J Clin Pharmacol. 2014;57:121\u20136. https:\/\/doi.org\/10.1046\/j.1365-2125.2003.01875.x .","journal-title":"Br J Clin Pharmacol"},{"key":"90_CR3","volume-title":"Restrictions on the use of domperidone-containing medicines. EMA\/465179\/2014","author":"European Medicines Agency","year":"2014","unstructured":"European Medicines Agency. Restrictions on the use of domperidone-containing medicines. EMA\/465179\/2014. London: European Medicines Agency; 2014."},{"key":"90_CR4","unstructured":"SmPC: metoclopramide. Available at: https:\/\/www.medicines.org.uk\/emc\/product\/6283\/smpc . Accessed Aug 2018."},{"issue":"2","key":"90_CR5","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/clpt.1981.154","volume":"30","author":"CA Naranjo","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30(2):239\u201345.","journal-title":"Clin Pharmacol Ther"},{"issue":"5","key":"90_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5348\/ijcri-2012-05-116-RA-1","volume":"3","author":"MM Rumore","year":"2012","unstructured":"Rumore MM. Cardiovascular adverse effects of metoclopramide: review of literature. Int J Case Rep Images.\u00a02012;3(5):1\u201310.","journal-title":"Int J Case Rep Images"},{"issue":"4","key":"90_CR7","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/BF03021028","volume":"50","author":"Y Grenier","year":"2003","unstructured":"Grenier Y, Drolet P. Asystolic cardiac arrest: an unusual reaction following iv metoclopramide. Can J Anesth. 2003;50(4):333\u20135.","journal-title":"Can J Anesth"},{"key":"90_CR8","first-page":"1853","volume":"26","author":"G Bozzi","year":"1981","unstructured":"Bozzi G, Terranova P, Paolino C, Cialfi A, Gandini R, Bevilacqua M. The effects of acute administration of metoclopramide on atrial and AV conduction in man. Boll Soc Ital Cardiol. 1981;26:1853\u20135.","journal-title":"Boll Soc Ital Cardiol"},{"issue":"5","key":"90_CR9","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1111\/j.1365-2125.1977.tb00777.x","volume":"4","author":"DH Lawson","year":"1977","unstructured":"Lawson DH, Jick H. Adverse reactions to procainamide. Br J Clin Pharmacol. 1977;4(5):507\u201311.","journal-title":"Br J Clin Pharmacol"},{"issue":"3","key":"90_CR10","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0022-3565(25)24595-5","volume":"244","author":"JA Gylys","year":"1988","unstructured":"Gylys JA, Wright RN, Nicolosi WD, Buyniski JP, Crenshaw RR. BMY-25801, an antiemetic agent free of D2-dopamine receptor antagonist properties. J Pharmacol Exp Ther. 1988;244(3):830\u20137.","journal-title":"J Pharmacol Exp Ther"},{"key":"90_CR11","unstructured":"Woosley RL, Heise CW, Romero KA. QTdrugs List, AZCERT, Inc. Available at www.CredibleMeds.org . Accessed Aug 2018."}],"container-title":["Drug Safety - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s40800-018-0090-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40800-018-0090-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s40800-018-0090-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T07:02:15Z","timestamp":1751785335000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s40800-018-0090-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,7]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["90"],"URL":"https:\/\/doi.org\/10.1007\/s40800-018-0090-3","relation":{},"ISSN":["2199-1162","2198-977X"],"issn-type":[{"type":"print","value":"2199-1162"},{"type":"electronic","value":"2198-977X"}],"subject":[],"published":{"date-parts":[[2018,8,7]]},"assertion":[{"value":"7 August 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"No financial support was received for the conduct of this study or preparation of this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Laura Sijtsma, Carolina Keijsers, Ang\u00e8le Kerckhoffs, Willem Agema and Janet Bootsma declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Written informed consent was obtained for publication of this case report.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"24"}}