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The funders played no role in the design, execution, analysis and interpretation of the data, or writing of the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"Luca Soraci, Ersilia Paparazzo, Mirella Aurora Aceto, Francesco Bruno, Teresa Serra Cassano, Davide Lagrotteria, Salvatore Claudio Cosimo, Pierluigi Mercatante, Francesco Morelli, Maria Princiotto, Andrea Corsonello, Giuseppe Passarino, and Alberto Montesanto have no conflicts of interest that are directly relevant to the content of this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest\/Competing Interests"}},{"value":"This study was approved by the Regional Ethics Committee of Catanzaro, Italy (protocol CE 119\/2016).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Informed written consent was signed by all participants enrolled in the study or their legal representatives.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The datasets generated and analyzed during the current study are not publicly available because of institutional and ethical restrictions related to the privacy of NHRs. However, de-identified data may be available from the corresponding author upon reasonable request and with appropriate ethical approval.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of Data and Material"}},{"value":"Not applicable.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code Availability"}},{"value":"Conceptualization: LS, EP, and AM; methodology: LS, EP, and AM; formal analysis: LS, E.P., MAA, and AM; data curation: EP, MAA, FB, TSC, SG, FM, and AM; investigation: LS, EP, and AM; writing (original draft preparation): LS, EP, and AM; writing (review and editing): LS, MAA, FB, TSC, SG, SCC, PM, FM, MP, and AM; supervision: AC, GP; funding acquisition: GP. All authors have read and agreed to the published version of the manuscript.","order":9,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 Contributions"}}]}}