{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:29:32Z","timestamp":1762867772780,"version":"3.37.3"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Geriatr Med"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s41999-019-00176-2","type":"journal-article","created":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T09:02:54Z","timestamp":1552899774000},"page":"473-481","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Potentially inappropriate prescriptions of antithrombotic therapies in older outpatients: a French multicenter cross-sectional study"],"prefix":"10.1007","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7724-7971","authenticated-orcid":false,"given":"S\u00e9gol\u00e8ne","family":"Dubois-Puechlong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Mille","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Hindlet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yann","family":"de Rycke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Tubach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Bonnet-Zamponi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"key":"176_CR1","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1001\/jama.289.9.1107","volume":"289","author":"JH Gurwitz","year":"2003","unstructured":"Gurwitz JH, Field TS, Harrold LR et al (2003) Incidence and preventability of adverse drug events among older persons in the ambulatory setting. JAMA 289:1107\u20131116","journal-title":"JAMA"},{"issue":"8","key":"176_CR2","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1002\/phar.1287","volume":"33","author":"C Kongkaew","year":"2013","unstructured":"Kongkaew C, Hann M, Mandal J et al (2013) Risk factors for hospital admissions associated with adverse drug events. Pharmacotherapy 33(8):827\u2013837","journal-title":"Pharmacotherapy"},{"issue":"20","key":"176_CR3","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.1001\/jama.2016.16201","volume":"316","author":"N Shehab","year":"2016","unstructured":"Shehab N, Lovegrove MC, Geller A et al (2016) US emergency department visits for outpatient adverse drug events, 2013\u20132014. JAMA 316(20):2115\u20132125","journal-title":"JAMA"},{"issue":"5","key":"176_CR4","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1111\/jgs.14099","volume":"64","author":"MH Eckman","year":"2016","unstructured":"Eckman MH, Lip GY, Wise RE et al (2016) Using an atrial fibrillation decision support tool for thromboprophylaxis in atrial fibrillation: effect of sex and age. J Am Geriatr Soc 64(5):1054\u20131060","journal-title":"J Am Geriatr Soc"},{"issue":"1","key":"176_CR5","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1007\/s11096-015-0199-8","volume":"38","author":"SH Chau","year":"2016","unstructured":"Chau SH, Jansen AP, van de Ven PM et al (2016) Clinical medication reviews in elderly patients with polypharmacy: across-sectional study on drug-related problems in the Netherlands. Int J Clin Pharm 38(1):46\u201353","journal-title":"Int J Clin Pharm"},{"issue":"4","key":"176_CR6","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1111\/j.1365-2125.2007.03064.x","volume":"65","author":"K Wester","year":"2008","unstructured":"Wester K, J\u00f6nsson AK, Spigset O et al (2008) Incidence of fatal adverse drug reactions. Br J Clin Pharmacol 65(4):573\u2013579","journal-title":"Br J Clin Pharmacol"},{"issue":"2","key":"176_CR7","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1093\/ageing\/afu145","volume":"44","author":"D O\u2019Mahony","year":"2014","unstructured":"O\u2019Mahony D, O\u2019Sullivan D, Byrne S et al (2014) Stopp & Start criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing 44(2):213\u2013218. \n                    https:\/\/doi.org\/10.1093\/ageing\/afu145","journal-title":"Age Ageing"},{"key":"176_CR8","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.eurger.2010.01.007","volume":"1","author":"D O\u2019Mahony","year":"2010","unstructured":"O\u2019Mahony D, Gallagher P, Ryan C et al (2010) Stopp&Start criteria: a new approach to detecting potentially inappropriate prescribing in old age. Eur Geriatr Med 1:45\u201351","journal-title":"Eur Geriatr Med"},{"key":"176_CR9","doi-asserted-by":"publisher","first-page":"72","DOI":"10.5414\/CPP46072","volume":"46","author":"P Gallagher","year":"2008","unstructured":"Gallagher P, Ryan C, Byrne S et al (2008) STOPP and START: consensus validation. Int J Clin Pharm Ther 46:72\u201383","journal-title":"Int J Clin Pharm Ther"},{"key":"176_CR10","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1093\/ageing\/afm118","volume":"36","author":"PJ Barry","year":"2007","unstructured":"Barry PJ, Gallagher P, Ryan C et al (2007) Start: an evidence-based screening tool to detect prescribing omissions in elderly patients. Age Ageing 36:632\u2013638","journal-title":"Age Ageing"},{"issue":"12","key":"176_CR11","doi-asserted-by":"publisher","first-page":"1968","DOI":"10.1345\/aph.1P426","volume":"44","author":"HB Levy","year":"2010","unstructured":"Levy HB, Marcus EL, Christen C (2010) Beyond the beers criteria: a comparative overview of explicit criteria. Ann Pharmacother 44(12):1968\u20131975","journal-title":"Ann Pharmacother"},{"key":"176_CR12","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2147\/CIA.S9564","volume":"5","author":"RL Page","year":"2010","unstructured":"Page RL, Linnebur SA, Bryant LL et al (2010) Prescribing in the hospitalized elderly patients: defining the problem, evaluation tools, possible solutions. Clin Interv Aging 5:75\u201387","journal-title":"Clin Interv Aging"},{"issue":"11","key":"176_CR13","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1001\/archinternmed.2011.215","volume":"171","author":"H Hamilton","year":"2011","unstructured":"Hamilton H, Gallagher P, Ryan C et al (2011) Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients. Arch Intern Med 171(11):1013\u20131019","journal-title":"Arch Intern Med"},{"issue":"4","key":"176_CR14","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1093\/gerona\/glq236","volume":"66","author":"MA Steinman","year":"2011","unstructured":"Steinman MA, Hanlon JA, Sloane RJ et al (2011) Do geriatric conditions increase risk of adverse drug reactions in ambulatory elders? Results from the VAGEM drug study. J Gerontol A Biol Sci Med Sci. 66(4):444\u2013451","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"176_CR15","doi-asserted-by":"publisher","first-page":"819","DOI":"10.2147\/CIA.S107394","volume":"11","author":"H Getachew","year":"2016","unstructured":"Getachew H, Bhagavathula AS, Abebe TB et al (2016) Inappropriate prescribing in anti-thrombotic therapy in Ethiopian elderly population using updated 2015 STOPP\/START criteria: a cross-sectional study. Clin Interv Aging 11:819\u2013827","journal-title":"Clin Interv Aging"},{"issue":"12","key":"176_CR16","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1007\/s00228-015-1954-4","volume":"71","author":"E Tommelein","year":"2015","unstructured":"Tommelein E, Mehuys E, Boussery K et al (2015) Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature review. Eur J Clin Pharmacol 71(12):1415\u20131427. \n                    https:\/\/doi.org\/10.1007\/s00228-015-1954-4","journal-title":"Eur J Clin Pharmacol"},{"key":"176_CR17","unstructured":"R Development Core Team  (2008) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0. \n                    http:\/\/www.R-project.org"},{"key":"176_CR18","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1111\/j.1365-2125.2009.03531.x","volume":"68","author":"C Ryan","year":"2009","unstructured":"Ryan C, O\u2019Mahony D, Kennedy J et al (2009) Potentially inappropriate prescribing in an Irish elderly population in primary care. Br J Clin Pharmacol 68:936\u2013947","journal-title":"Br J Clin Pharmacol"},{"issue":"4","key":"176_CR19","doi-asserted-by":"publisher","first-page":"e95536","DOI":"10.1371\/journal.pone.0095536","volume":"9","author":"S Vezmar Kova\u010devi\u0107","year":"2014","unstructured":"Vezmar Kova\u010devi\u0107 S, Simi\u0161i\u0107 M, Stojkov Rudinski S et al (2014) Potentially inappropriate prescribing in older primary care patients. PLoS One 9(4):e95536","journal-title":"PLoS One"},{"issue":"1","key":"176_CR20","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.aprim.2014.03.013","volume":"47","author":"J Filomena Paci","year":"2015","unstructured":"Filomena Paci J, Garc\u00eda Alfaro M, Redondo Alonso FJ et al (2015) Inapropriate prescribing in polymedicated patients over 64\u00a0years old in primary care. Aten Primaria 47(1):38\u201347","journal-title":"Aten Primaria"},{"key":"176_CR21","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1111\/jep.12319","volume":"21","author":"MG Oliveira","year":"2015","unstructured":"Oliveira MG, Amorim WW, de Jesus SR et al (2015) A comparison of the Beers and STOPP criteria for identifying the use of potentially inappropriate medications among elderly patients in primary care. J Eval Clin Pract 21:320\u2013325","journal-title":"J Eval Clin Pract"},{"issue":"1","key":"176_CR22","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s00228-015-1957-1","volume":"72","author":"I Projovic","year":"2016","unstructured":"Projovic I, Vukadinovic D, Milovanovic O et al (2016) Risk factors for potentially inappropriate prescribing to older patients in primary care. Eur J Clin Pharmacol 72(1):93\u2013107","journal-title":"Eur J Clin Pharmacol"},{"key":"176_CR23","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1007\/s11096-012-9733-0","volume":"35","author":"C Ryan","year":"2013","unstructured":"Ryan C, O\u2019Mahony D, O\u2019Donovan D\u00d3 et al (2013) A comparison of the application of StoppStart to patients drugs lists with and without clinical information. Int J Clin Pharm 35:230\u2013235","journal-title":"Int J Clin Pharm"},{"issue":"2","key":"176_CR24","doi-asserted-by":"publisher","first-page":"383","DOI":"10.2147\/CIA.S2468","volume":"3","author":"RL Bushardt","year":"2008","unstructured":"Bushardt RL, Massey EB, Simpson TW et al (2008) Polypharmacy: misleading, but manageable. Clin Interv Ageing 3(2):383\u2013389","journal-title":"Clin Interv Ageing"},{"issue":"3","key":"176_CR25","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1016\/j.archger.2014.08.006","volume":"59","author":"JB Beuscart","year":"2014","unstructured":"Beuscart JB, Dupont C, Defebvre MM et al (2014) Potentially inappropriate medications (PIMs) and anticholinergic levels in the elderly: a population-based study in a French region. Arch Gerontol Geriatr 59(3):630\u2013635","journal-title":"Arch Gerontol Geriatr"},{"key":"176_CR26","unstructured":"Rapport IRDES. La polym\u00e9dication au regard de diff\u00e9rents indicateurs de sa mesure: impact sur la pr\u00e9valence, les classes th\u00e9rapeutiques concern\u00e9es et les facteurs associ\u00e9s. Octobre 2015. Available in an English short version at: \n                    http:\/\/www.irdes.fr\/english\/issues-in-health-economics\/204-polypharmacy-definitions-measurement-and-stakes-involved.pdf"},{"issue":"12","key":"176_CR27","doi-asserted-by":"publisher","first-page":"e0167586","DOI":"10.1371\/journal.pone.0167586","volume":"11","author":"E Blanco-Reina","year":"2016","unstructured":"Blanco-Reina E, Garc\u00eda-Merino MR, Oca\u00f1a-Riola R et al (2016) Assessing potentially inappropriate prescribing in community-dwelling older patients using the updated version of STOPP-START criteria: a comparison of profiles and prevalences with respect to the original version. PLoS One 11(12):e0167586","journal-title":"PLoS One"},{"issue":"3","key":"176_CR28","doi-asserted-by":"publisher","first-page":"e019003","DOI":"10.1136\/bmjopen-2017-019003","volume":"8","author":"D O\u2019Riordan","year":"2018","unstructured":"O\u2019Riordan D, Aubert CE, Walsh KA et al (2018) Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study. BMJ Open 8(3):e019003","journal-title":"BMJ Open"},{"key":"176_CR29","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.revmed.2014.03.100","volume":"35","author":"G Jouin","year":"2014","unstructured":"Jouin G, Paya D, Michel B et al (2014) R\u00e9-\u00e9valuation th\u00e9rapeutique des personnes \u00e2g\u00e9es \u00e0 l\u2019occasion d\u2019une hospitalisation: \u00e9tude prospective aupr\u00e8s de 97 patients. Rev Med Int 35:77\u201378","journal-title":"Rev Med Int"},{"issue":"6","key":"176_CR30","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.regg.2013.04.004","volume":"48","author":"JA Hern\u00e1ndez Perella","year":"2013","unstructured":"Hern\u00e1ndez Perella JA, Mas Garriga X, Riera Cervera D et al (2013) Inappropriate prescribing of drugs in older people attending primary care health centers: detection using STOPP-START criteria. Rev Esp Geriatr Gerontol 48(6):265\u2013268","journal-title":"Rev Esp Geriatr Gerontol"},{"key":"176_CR31","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1056\/NEJMsa1103053","volume":"365","author":"DS Budnitz","year":"2011","unstructured":"Budnitz DS, Lovegrove MC, Shehab N et al (2011) Emergency hospitalizations for adverse drug events in older Americans. New Engl J Med 365:2002\u20132012","journal-title":"New Engl J Med"},{"key":"176_CR32","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s40266-013-0057-0","volume":"30","author":"V Milos","year":"2013","unstructured":"Milos V, Rekman E, Bondesson A et al (2013) Imporving the quality of pharmacotherapy in elderly primary care patients through medication reviews: a randomized controlled study. Drugs Aging 30:235\u2013246","journal-title":"Drugs Aging"},{"key":"176_CR33","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/S0002-9343(97)89519-8","volume":"100","author":"JT Hanlon","year":"1996","unstructured":"Hanlon JT, Weinberger M, Samsa GP et al (1996) A randomized, controlled trial of a clinical pharmacist intervention to improve inappropriate prescribing in elderly outpatients with polypharmacy. Am J Med 100:430\u2013437","journal-title":"Am J Med"},{"key":"176_CR34","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1046\/j.1532-5415.2001.49042.x","volume":"49","author":"JT Hanlon","year":"2001","unstructured":"Hanlon JT, Schmader KE, Ruby CM (2001) Suboptimal prescribing in older inpatients and outpatients. JAGS 49:200\u2013209","journal-title":"JAGS"}],"container-title":["European Geriatric Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s41999-019-00176-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s41999-019-00176-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s41999-019-00176-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T00:17:45Z","timestamp":1584404265000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s41999-019-00176-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,18]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["176"],"URL":"https:\/\/doi.org\/10.1007\/s41999-019-00176-2","relation":{},"ISSN":["1878-7657"],"issn-type":[{"type":"electronic","value":"1878-7657"}],"subject":[],"published":{"date-parts":[[2019,3,18]]},"assertion":[{"value":"11 September 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors have no financial or any other kind of personal conflicts with this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The university ethics committee approved the study protocol (no. NI-2016-03-03) and all procedures performed in studies involving human participants were in accordance with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}