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This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This research was conducted in full accordance with the ethical standards of the institutional research committee as well as with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this non-interventional observational retrospective study, patient data were referenced with the understanding and written consent of the patient, and all data were also anonymized and de-identified prior to analysis. In the3 case of non-adults, written consent was given by one of the parents. Full compliance with data protection and safeguarding of data was ensured and no information which could identify the patients was collected. Reporting was based on the recommendations of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) initiative [].","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}}]}}