{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T19:51:14Z","timestamp":1785527474643,"version":"3.56.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","award":["CSF-2023-008"],"award-info":[{"award-number":["CSF-2023-008"]}],"id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Dublin, Trinity College"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Geriatr Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Falls are a major tipping point in older adults, heralding functional decline and increased healthcare utilisation. Falls-risk\u2013increasing drugs (FRIDs) are a key risk factor for falls, but their influence on outcomes when prescribed after a fall is under-examined.<\/jats:p>\n                    <jats:p>This study examined the association between an index fall requiring medical attention and subsequent 2-year risk of falls and fractures, evaluating how FRID use modifies this relationship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analysed data from Waves 5 and 6 of The Irish Longitudinal Study on Ageing, including participants\u2009\u2265\u200970\u00a0years with 2-year follow-up.<\/jats:p>\n                    <jats:p>FRIDs were identified from medication lists using STOPPFall.<\/jats:p>\n                    <jats:p>Regression models were used to assess the association between index falls and falls\/fracture outcomes during follow-up: Falls, falls requiring medical attention, emergency department visits due to falls, and fractures. Two-way interactions were used to assess how FRID use modified this association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 1717 participants, 14% reported a fall requiring medical attention at baseline; 38% were prescribed\u2009\u2265\u20091 FRID.<\/jats:p>\n                    <jats:p>Index falls were associated with increased future falls (OR 2.65), falls requiring medical attention (OR 3.82), ED attendance due to a fall (OR 2.93), and fractures (OR 2.46) over 2\u00a0years (all p\u2009&lt;\u20090.01).<\/jats:p>\n                    <jats:p>Combined exposure to both a fall and FRIDs further amplified risk, with odds ratios ranging from 3.77 to 4.36 across outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A fall requiring medical attention is a strong predictor of future falls burden, and FRID use significantly amplifies this risk.<\/jats:p>\n                    <jats:p>These findings highlight the need for targeted medication review within comprehensive geriatric assessment for older people with falls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s41999-026-01549-0","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T15:29:27Z","timestamp":1785252567000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["How do falls-risk increasing drugs modify the association between index falls and future falls and fracture burden? 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