{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:59:52Z","timestamp":1782932392220,"version":"3.54.5"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hormones"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s42000-022-00355-0","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T08:05:33Z","timestamp":1649059533000},"page":"271-276","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Seronegative phenotype in a pediatric population with Hashimoto\u2019s \ufeffthyroiditis"],"prefix":"10.1007","volume":"21","author":[{"given":"Caterina","family":"Rizzardi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2230-7148","authenticated-orcid":false,"given":"Roberto","family":"Franceschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittoria","family":"Cauvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Bellizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Liguori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Longhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiorenzo","family":"Lupi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Soffiati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Radetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"key":"355_CR1","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1530\/acta.0.1210129","volume":"121","author":"R Gutekunst","year":"1989","unstructured":"Gutekunst R, Hafermann W, Mansky T, Scriba PC (1989) Ultrasonography related to clinical and laboratory findings in lymphocytic thyroiditis. Acta Endocrinol (Copenh) 121:129\u2013135. https:\/\/doi.org\/10.1530\/acta.0.1210129","journal-title":"Acta Endocrinol (Copenh)"},{"key":"355_CR2","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1007\/BF03343925","volume":"24","author":"T Rago","year":"2001","unstructured":"Rago T, Chiovato L, Grasso L, Pinchera A (2001) Vitti P (2001) Thyroid ultrasonography as a tool for detecting thyroid autoimmune diseases and predicting thyroid dysfunction in apparently healthy subjects. J Endocrinol Invest 24:763\u2013769","journal-title":"J Endocrinol Invest"},{"key":"355_CR3","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1530\/EJE-14-0147","volume":"37","author":"M Rotondi","year":"2014","unstructured":"Rotondi M, Coperchini F, Magri F, Chiovato L (2014) Serum-negative autoimmune thyroiditis: what\u2019s in a name? J Endocrinol Invest 37:589\u2013591. https:\/\/doi.org\/10.1530\/EJE-14-0147","journal-title":"J Endocrinol Invest"},{"key":"355_CR4","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1007\/s40618-020-01249-x","volume":"43","author":"L Croce","year":"2020","unstructured":"Croce L, De Martinis L, Pinto S, Coperchini F, Dito G, Bendotti G et al (2020) Compared with classic Hashimoto\u2019s thyroiditis, chronic autoimmune serum-negative thyroiditis requires a lower substitution dose of L-thyroxine to correct hypothyroidism. J Endocrinol Invest 43:1631\u20131636. https:\/\/doi.org\/10.1007\/s40618-020-01249-x","journal-title":"J Endocrinol Invest"},{"key":"355_CR5","doi-asserted-by":"publisher","first-page":"4749","DOI":"10.1210\/jc.2008-0823","volume":"93","author":"G Radetti","year":"2008","unstructured":"Radetti G, Kleon W, Buzi F, Crivellaro C, Pappalardo L, di Iorgi N et al (2008) Thyroid function and structure are affected in childhood obesity. J Clin Endocrinol Metab 93:4749\u20134754. https:\/\/doi.org\/10.1210\/jc.2008-0823","journal-title":"J Clin Endocrinol Metab"},{"key":"355_CR6","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1007\/BF03344156","volume":"29","author":"E Cacciari","year":"2006","unstructured":"Cacciari E, Milani S, Balsamo A, Spada E, Bona G, Cavallo L et al (2006) Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr). J Endocrinol Invest 29:581\u2013593. https:\/\/doi.org\/10.1007\/BF03344156","journal-title":"J Endocrinol Invest"},{"key":"355_CR7","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1136\/adc.51.3.170","volume":"51","author":"JM Tanner","year":"1976","unstructured":"Tanner JM, Whitehouse RH (1976) Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child 51:170\u2013179. https:\/\/doi.org\/10.1136\/adc.51.3.170","journal-title":"Arch Dis Child"},{"key":"355_CR8","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1210\/jcem.79.2.8045982","volume":"79","author":"P Vitti","year":"1994","unstructured":"Vitti P, Martino E, Aghini-Lombardi F, Rago T, Antonangeli L, Maccherini D et al (1994) Thyroid volume measurement by ultrasound in children as a tool for the assessment of mild iodine deficiency. J Clin Endocrinol Metab 79:600\u2013603. https:\/\/doi.org\/10.1210\/jcem.79.2.8045982","journal-title":"J Clin Endocrinol Metab"},{"issue":"S2","key":"355_CR9","first-page":"107","volume":"60","author":"G Cesaretti","year":"2003","unstructured":"Cesaretti G, Saggese G (2003) Accurate ultrasonographic evaluation in autoimmune juvenile thyroiditis with subclinical hypothyroidism: a useful tool to establish the treatment. A retrospective study. Horm Res 60(S2):107","journal-title":"Horm Res"},{"key":"355_CR10","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1089\/thy.2000.10.251","volume":"10","author":"OM Pedersen","year":"2000","unstructured":"Pedersen OM, Aardal NP, Larssen TB, Myking O, Vik-Mo H (2000) The value of ultrasonography in predicting autoimmune thyroid disease. Thyroid 10:251\u2013259. https:\/\/doi.org\/10.1089\/thy.2000.10.251","journal-title":"Thyroid"},{"key":"355_CR11","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1210\/jc.2007-2368","volume":"93","author":"Y Li","year":"2008","unstructured":"Li Y, Teng D, Shan Z, Teng X, Guan H, Yu X et al (2008) Antithyroperoxidase and antithyroglobulin antibodies in a five-year follow-up survey of populations with different iodine intakes. J Clin Endocrinol Metab 93:1751\u20131757. https:\/\/doi.org\/10.1210\/jc.2007-2368","journal-title":"J Clin Endocrinol Metab"},{"key":"355_CR12","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1177\/0300060514562487","volume":"43","author":"YR Yan","year":"2015","unstructured":"Yan YR, Gao XL, Zeng J, Liu Y, Lv QG, Jiang J et al (2015) The association between thyroid autoantibodies in serum and abnormal function and structure of the thyroid. J Int Med Res 43:412\u2013423. https:\/\/doi.org\/10.1177\/0300060514562487","journal-title":"J Int Med Res"},{"key":"355_CR13","doi-asserted-by":"publisher","first-page":"2757","DOI":"10.1210\/jc.2018-02399","volume":"104","author":"MR Licenziati","year":"2019","unstructured":"Licenziati MR, Valerio G, Vetrani I, De Maria G, Liotta F, Radetti G (2019) Altered Thyroid Function and Structure in Children and Adolescents Who Are Overweight and Obese: Reversal After Weight Loss. J Clin Endocrinol Metab 104:2757\u20132765. https:\/\/doi.org\/10.1210\/jc.2018-02399","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Hormones"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42000-022-00355-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s42000-022-00355-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42000-022-00355-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T02:19:56Z","timestamp":1653445196000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s42000-022-00355-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,4]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["355"],"URL":"https:\/\/doi.org\/10.1007\/s42000-022-00355-0","relation":{},"ISSN":["1109-3099","2520-8721"],"issn-type":[{"value":"1109-3099","type":"print"},{"value":"2520-8721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,4]]},"assertion":[{"value":"26 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 February 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The latest revision of the Declaration of Helsinki and the Oviedo Convention were the basis for the ethical conduct of the study. The study protocol was designed and conducted to ensure adherence to the principles and procedures of good clinical practice and to comply with the Italian laws. Ethics approval was not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individuals included in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no conflicts of interest to declare.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}