{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:47:04Z","timestamp":1790812024498,"version":"4.1.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology , Ministry of Science and Technology","doi-asserted-by":"publisher","award":["BT\/CRS0226\/CRS -11\/17"],"award-info":[{"award-number":["BT\/CRS0226\/CRS -11\/17"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Braz J Microbiol"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1007\/s42770-019-00116-z","type":"journal-article","created":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T16:17:32Z","timestamp":1568996252000},"page":"1105-1114","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Development and evaluation of LAMP-coupled lateral flow device for the detection of MAP in livestock at point of care resource-limited areas"],"prefix":"10.1007","volume":"50","author":[{"given":"Rudrama Devi","family":"Punati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prudhvi Chand","family":"Mallepaddi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Revathi","family":"Poonati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumendra Nath","family":"Maity","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagdip Singh","family":"Sohal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavi Kishor B.","family":"Polavarapu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rathnagiri","family":"Polavarapu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,9,20]]},"reference":[{"key":"116_CR1","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/0378-1135(94)90048-5","volume":"40","author":"DM Collins","year":"1994","unstructured":"Collins DM, Radford AJ, De Lisle GW, Billman Jacobe H (1994) Diagnosis and epidemiology of bovine tuberculosis using molecular biological approaches. Vet Microbiol 40:83\u201394","journal-title":"Vet Microbiol"},{"key":"116_CR2","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/2193-1801-1-47","volume":"1","author":"E Momotani","year":"2012","unstructured":"Momotani E, Ozaki H, Hori M, Yamamoto S, Kuribayashi T, Eda S, Ikegami M (2012) Mycobacterium avium subsp. paratuberculosis lipophilic antigen causes Crohn\u2019s disease-type necrotizing colitis in mice. Springerplus. 1:47","journal-title":"Springerplus."},{"key":"116_CR3","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1016\/S0140-6736(04)17058-X","volume":"364","author":"SA Naser","year":"2004","unstructured":"Naser SA, Ghobrial G, Romero C, Valentine JF (2004) Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn\u2019s disease. Lancet. 364:1039\u20131044","journal-title":"Lancet."},{"key":"116_CR4","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1017\/S0950268800052705","volume":"116","author":"B Cetinkaya","year":"1996","unstructured":"Cetinkaya B, Egan K, Harbour DA, Morgan KL (1996) An abattoir based study of the prevalence of subclinical Johne\u2019s disease in adult cattle in south west England. Epidemiol Infect 116:373\u2013379","journal-title":"Epidemiol Infect"},{"key":"116_CR5","first-page":"218","volume":"74","author":"RJ Chiodini","year":"1984","unstructured":"Chiodini RJ, Van Kruiningen HJ, Merkal RS (1984) Ruminant paratuberculosis (Johne\u2019s disease): the current status and future prospects. Cornell Vet 74:218\u2013262","journal-title":"Cornell Vet"},{"key":"116_CR6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1080\/00480169.2003.36341","volume":"51","author":"GW De Lisle","year":"2003","unstructured":"De Lisle GW, Yates GF, Montgomery H (2003) The emergence of Mycobacterium paratuberculosis in farmed deer in New Zealand. A review of 619 cases. N Z Vet J 51:58\u201362","journal-title":"N Z Vet J"},{"key":"116_CR7","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.cimid.2007.06.002","volume":"31","author":"SV Singh","year":"2008","unstructured":"Singh SV, Singh AV, Singh R, Sharma S, Shukla N, Misra S, Singh PK, Sohal JS, Kumar H, Patil PK, Misra P, Sandhu KS (2008) Sero-prevalence of bovine Johne\u2019s disease in buffaloes and cattle population of North India using indigenous ELISA kit based on native Mycobacterium avium subspecies paratuberculosis 'Bison type' genotype of goat origin. Comp Immunol Microbiol Infect Dis 31:419\u2013433","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"116_CR8","first-page":"1","volume":"1","author":"AV Singh","year":"2010","unstructured":"Singh AV, Singh SV, Singh PK, Sohal JS, Mahour K (2010) Sero-surveillance of Mycobacterium avium subspecies paratuberculosis infection in domestic livestock in North India using indigenous absorbed ELISA test. J Adv Lab Res Biol 1:1\u20135","journal-title":"J Adv Lab Res Biol"},{"issue":"Suppl 1","key":"116_CR9","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/tbed.12216","volume":"61","author":"SV Singh","year":"2014","unstructured":"Singh SV, Singh PK, Singh AV, Sohal JS, Kumar N, Chaubey KK, Gupta S, Rawat KD, Kumar A, Bhatia AK, Srivastav AK, Dhama K (2014) Bio-load and bio-type profiles of Mycobacterium avium subspecies paratuberculosis infection in the domestic livestock population endemic for Johne\u2019s disease: a survey of 28 years (1985-2013) in India. Transbound Emerg Dis 61(Suppl 1):43\u201355","journal-title":"Transbound Emerg Dis"},{"key":"116_CR10","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1111\/j.1751-0813.2001.tb11980.x","volume":"79","author":"RJ Whittington","year":"2001","unstructured":"Whittington RJ, Sergeant ESG (2001) Progress towards understanding the spread, detection and control of Mycobacterium avium subsp. paratuberculosis in animal populations. Aust Vet J 79:267\u2013278","journal-title":"Aust Vet J"},{"key":"116_CR11","unstructured":"Ristow P, Marassi CD, Rodrigues ABF, Oelemann WMR, Rocha F, Santos ASO, Carvalho ECQ, Carvalho CB, Ferreira R, Fonseca LS, Lilenbaum W (2004) Investigation of Bovine Paratuberculosis on a Brazilian dairy herd through serological, bacteriological, Molecular & Anatomopathological tools. Anais XVII Congr. Latinoamericano e X Congr. Argentino de Microbiologia, Buenos Aires"},{"key":"116_CR12","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1177\/104063879700900406","volume":"9","author":"JR Stabel","year":"1997","unstructured":"Stabel JR (1997) An improved method for cultivation of Mycobacterium paratuberculosis from bovine faecal samples and comparison to three other methods. J Vet Diagn Investig 9:375\u2013380","journal-title":"J Vet Diagn Investig"},{"key":"116_CR13","first-page":"1237","volume-title":"The Mycobacteria: a source book","author":"RS Merkal","year":"1984","unstructured":"Merkal RS (1984) Paratuberculosis. In: Kubica GP, Wayne LG (eds) The Mycobacteria: a source book. Marcel. Dekker Inc, New York, NY, pp 1237\u20131249"},{"key":"116_CR14","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1177\/104063879100300424","volume":"3","author":"DL Whipple","year":"1991","unstructured":"Whipple DL, Calihan DR, Jarnagin JL (1991) Cultivation of Mycobacterium Paratuberculosis from bovine fecal specimens and a suggested standardized procedure. J Vet Diagn Investig 3:368\u2013373","journal-title":"J Vet Diagn Investig"},{"key":"116_CR15","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/0378-1135(94)90140-6","volume":"41","author":"F Hilbink","year":"1994","unstructured":"Hilbink F, West DM, de Lisle GW, Kittelberger R, Hosie BD, Hutton J, Cooke MM, Penrose M (1994) Comparison of a complement fixation test, a gel diffusion test and two absorbed and unabsorbed ELISAs for the diagnosis of paratuberculosis in sheep. Vet Microbiol 41:107\u2013116","journal-title":"Vet Microbiol"},{"key":"116_CR16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1111\/j.1751-0813.1999.tb11679.x","volume":"77","author":"WL McDonald","year":"1999","unstructured":"McDonald WL, Ridge SE, Hope AF, Condron RJ (1999) Evaluation of diagnostic tests for Johne\u2019s disease in young cattle. Aust Vet J 77:113\u2013119","journal-title":"Aust Vet J"},{"key":"116_CR17","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1128\/JCM.30.5.1134-1139.1992","volume":"30","author":"DC Sockett","year":"1992","unstructured":"Sockett DC, Conrad TA, Thomas CB, Collins MT (1992) Evaluation of four serological tests for bovine paratuberculosis. J Clin Microbiol 30:1134\u20131139","journal-title":"J Clin Microbiol"},{"key":"116_CR18","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S0165-2427(01)00253-7","volume":"79","author":"JR Stabel","year":"2001","unstructured":"Stabel JR, Whitlock RH (2001) An evaluation of a modified interferon-gamma assay for the detection of paratuberculosis in dairy herds. Vet Immunol Immunopathol 79:69\u201381","journal-title":"Vet Immunol Immunopathol"},{"key":"116_CR19","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/j.1574-6968.2001.tb10536.x","volume":"196","author":"B Strommenger","year":"2001","unstructured":"Strommenger B, Stevenson K, Gerlach GF (2001) Isolation and diagnostic potential of ISMav2, a novel insertion sequence-like element from Mycobacterium avium subspecies paratuberculosis. FEMS Microbiol Lett 196:31\u201337","journal-title":"FEMS Microbiol Lett"},{"key":"116_CR20","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1111\/j.1574-6968.2004.tb09686.x","volume":"237","author":"D Rodriguez-Lazaro","year":"2004","unstructured":"Rodriguez-Lazaro D, Lloyd J, Herrewegh A, Ikonomopoulos J, D\u2019Agostino M, Pla M, Cook N (2004) A molecular beacon-based real-time NASBA assay for detection of Mycobacterium avium subsp. paratuberculosis in water and milk. FEMS Microbiol Lett 237:119\u2013126","journal-title":"FEMS Microbiol Lett"},{"key":"116_CR21","volume":"2010","author":"PK Singh","year":"2010","unstructured":"Singh PK, Singh SV, Kumar H, Sohal JS, Singh AV (2010) Diagnostic application of IS900 PCR using blood as a source sample for the detection of Mycobacterium avium subspecies Paratuberculosis in early and subclinical cases of caprine paratuberculosis. Vet Med Int 2010:748621","journal-title":"Vet Med Int"},{"key":"116_CR22","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/0378-1135(93)90095-O","volume":"36","author":"DM Collins","year":"1993","unstructured":"Collins DM, Stephens DM, De Lisle GW (1993) Comparison of polymerase chain reaction tests and fecal culture for detecting Mycobacterium Paratuberculosis in bovine feces. Vet Microbiol 36:289\u2013299","journal-title":"Vet Microbiol"},{"key":"116_CR23","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1128\/JCM.40.1.287-291.2002","volume":"40","author":"Y Fang","year":"2002","unstructured":"Fang Y, Wu WH, Pepper JL, Larsen JL, Marras SA, Nelson EA, Epperson WB, Christopher Hennings J (2002) Comparison of real-time, quantitative PCR with molecular beacons to nested PCR and culture methods for detection of Mycobacterium avium subsp. paratuberculosis in bovine fecal samples. J Clin Microbiol 40:287\u2013291","journal-title":"J Clin Microbiol"},{"key":"116_CR24","doi-asserted-by":"publisher","first-page":"E63","DOI":"10.1093\/nar\/28.12.e63","volume":"28","author":"T Notomi","year":"2000","unstructured":"Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T (2000) Loop-mediated isothermal amplification of DNA. Nucleic Acids Res 28:E63\u2013E663","journal-title":"Nucleic Acids Res"},{"key":"116_CR25","unstructured":"OIE Terrestrial manual (2014) Paratuberculosis (Johne\u2019s disease). Chapter 2.1.15"},{"key":"116_CR26","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1177\/104063870401600603","volume":"16","author":"S Taddei","year":"2004","unstructured":"Taddei S, Robbi C, Cesena C, Rossi I, Schiano E, Arrigoni N, Vicenzoni G, Cavirani S (2004) Detection of Mycobacterium avium subsp. paratuberculosis in bovine fecal samples: comparison of three polymerase chain reaction-based diagnostic tests with a conventional culture method. J Vet Diagn Investig 16:503\u2013508","journal-title":"J Vet Diagn Investig"},{"key":"116_CR27","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1128\/JCM.28.5.933-937.1990","volume":"28","author":"PH Vary","year":"1990","unstructured":"Vary PH, Andersen PR, Green E, Hermon Taylor J, Mcfadden JJ (1990) Use of highly specific DNA probes and the polymerase chain reaction to detect Mycobacterium Paratuberculosis in Johne's disease. J Clin Microbiol 28:933\u2013937","journal-title":"J Clin Microbiol"},{"key":"116_CR28","doi-asserted-by":"publisher","first-page":"704","DOI":"10.4269\/ajtmh.18-0177","volume":"99","author":"PC Mallepaddi","year":"2018","unstructured":"Mallepaddi PC, Lai MY, Podha S, Ooi CH, Liew JW, Polavarapu R, Lau YL (2018) Development of loop mediated isothermal amplification based lateral flow device method for the detection of malaria. Am J Trop Med Hyg 99:704\u2013708","journal-title":"Am J Trop Med Hyg"},{"key":"116_CR29","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.exppara.2013.03.031","volume":"134","author":"R Surabattula","year":"2013","unstructured":"Surabattula R, Vejandla MP, Mallepaddi PC, Faulstich K, Polavarapu R (2013) Simple, rapid, inexpensive platform for the diagnosis of malaria by loop mediated isothermal amplification (LAMP). Exp Parasitol 134:333\u2013340","journal-title":"Exp Parasitol"},{"key":"116_CR30","first-page":"843","volume":"45","author":"JS Sohal","year":"2007","unstructured":"Sohal JS, Singh SV, Subodh S, Singh AV, Singh PK, Sheoran N, Sandhu K, Narayanasamy K, Maitra A (2007) Mycobacterium avium subspecies paratuberculosis diagnosis and strain typing present status and future developments. Indian J Exp Biol 45:843\u2013852","journal-title":"Indian J Exp Biol"},{"key":"116_CR31","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1128\/JCM.01986-08","volume":"47","author":"RJ Whittington","year":"2009","unstructured":"Whittington RJ (2009) Factors affecting isolation and identification of Mycobacterium avium subsp. paratuberculosis from fecal and tissue samples in a liquid culture system. J Clin Microbiol 47:614\u2013622","journal-title":"J Clin Microbiol"},{"key":"116_CR32","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0378-1135(00)00324-2","volume":"77","author":"RH Whitlock","year":"2000","unstructured":"Whitlock RH, Wells SJ, Sweeney RW, Van Tiem J (2000) ELISA and fecal culture for Paratuberculosis (Johne\u2019s disease): sensitivity and specificity of each method. Vet Microbiol 77:387\u2013398","journal-title":"Vet Microbiol"},{"key":"116_CR33","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.rvsc.2011.05.017","volume":"92","author":"E Castellanos","year":"2012","unstructured":"Castellanos E, de JL, Dominguez L, Aranaz A (2012) Progress in molecular typing of Mycobacterium avium subspecies paratuberculosis. Res Vet Sci 92:169\u2013179","journal-title":"Res Vet Sci"},{"key":"116_CR34","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/j.1865-1682.2007.01009.x","volume":"55","author":"PJ Pinedo","year":"2008","unstructured":"Pinedo PJ, Rae DO, Williams JE, Donovan GA, Melendez P, Buergelt CD (2008) Association among results of serum ELISA, fecal culture and nested PCR on milk, blood and faeces for the detection of paratuberculosis in dairy cows. Transbound Emerg Dis 55:125\u2013133","journal-title":"Transbound Emerg Dis"},{"key":"116_CR35","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1128\/JCM.30.5.1216-1219.1992","volume":"30","author":"JWB Van Der Giessen","year":"1992","unstructured":"Van Der Giessen JWB, Haring RM, Vauclare E, Eger A, Haagsma J, Van Der Zeijst BAM (1992) Evaluation of the abilities of three diagnostic tests based on the polymerase chain reaction to detect Mycobacterium paratuberculosis in cattle: application in a control program. J Clin Microbiol 30:1216\u20131219","journal-title":"J Clin Microbiol"},{"key":"116_CR36","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.vetmic.2007.07.016","volume":"25","author":"P Mobius","year":"2008","unstructured":"Mobius P, Hotzel H, Rassbach A, Kohler H (2008) Comparison of 13 single-rounds and nested PCR assays targeting IS900, ISMav2, f57 and locus 255 for detection of Mycobacterium avium subsp. paratuberculosis. Vet Microbiol 25:324\u2013333","journal-title":"Vet Microbiol"},{"key":"116_CR37","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.ijmyco.2014.09.015","volume":"4","author":"S Safi","year":"2015","unstructured":"Safi S, Heidarnejhad O, Mosavari N, Sakha M, Afshar D, Moazami L, Meshkat M, Keshavarz R, Taheri M, Pajoohi RA, Tadayon K, Reshadi S, Dashtipour S (2015) Comparative evaluation of LAMP and nested-PCR for the diagnosis of bovine paratuberculosis. Intern J Mycobacteriol 4:98\u2013102","journal-title":"Intern J Mycobacteriol"},{"key":"116_CR38","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.fm.2017.10.001","volume":"70","author":"M Lalle","year":"2018","unstructured":"Lalle M, Possenti A, Dubey JP, Pozio E (2018) Loop-mediated isothermal amplification-lateral-flow dipstick (LAMP-LFD) to detect Toxoplasma gondii oocyst in ready-to-eat salad. Food Microbiol 70:137\u2013142","journal-title":"Food Microbiol"},{"key":"116_CR39","doi-asserted-by":"publisher","first-page":"192","DOI":"10.3389\/fcimb.2018.00192","volume":"8","author":"Y Wang","year":"2017","unstructured":"Wang Y, Li H, Wang Y, Zhang L, Xu J, Ye C (2017) Loop-mediated isothermal amplification label-based gold nano particles lateral flow biosensor for detection of Enterococcus faecalis and Staphylococcus aureus. Front Microbiol 8:192","journal-title":"Front Microbiol"},{"key":"116_CR40","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.aca.2015.11.015","volume":"903","author":"AB Nurul Najian","year":"2016","unstructured":"Nurul Najian AB, Engku Nur Syafirah EA, Ismail N, Mohamed M, Yean CY (2016) Development of multiplex loop mediated isothermal amplification (m-LAMP) label-based gold nano particles lateral flow dipstick biosensor for detection of pathogenic Leptospira. Anal Chim Acta 903:142\u2013148","journal-title":"Anal Chim Acta"},{"issue":"1","key":"116_CR41","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1111\/jam.14284","volume":"127","author":"MD Sange","year":"2019","unstructured":"Sange MD, Becker A, Hassan AA, Bulte M, Ganter M, Siebert U, Abdulmawjood A (2019) Development and validation of a loop-mediated isothermal amplification assay - a rapid and sensitive detection tool for Mycobacterium avium subsp. paratuberculosis in small ruminants. J Appl Microbiol 127(1):47\u201358","journal-title":"J Appl Microbiol"}],"container-title":["Brazilian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-019-00116-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s42770-019-00116-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-019-00116-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T23:12:10Z","timestamp":1600470730000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s42770-019-00116-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,20]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["116"],"URL":"https:\/\/doi.org\/10.1007\/s42770-019-00116-z","relation":{},"ISSN":["1517-8382","1678-4405"],"issn-type":[{"value":"1517-8382","type":"print"},{"value":"1678-4405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,20]]},"assertion":[{"value":"14 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All the experimental procedures were performed with the approval of the Institute Animal Ethics Committee, Genomix, Hyderabad, India. All applicable institutional guidelines for the care and use of animals were followed.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}