{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T03:22:17Z","timestamp":1775618537689,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T00:00:00Z","timestamp":1625270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T00:00:00Z","timestamp":1625270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Wuhan Health Scientific Research Key Project","award":["WX18A06"],"award-info":[{"award-number":["WX18A06"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Braz J Microbiol"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s42770-021-00554-8","type":"journal-article","created":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T20:02:40Z","timestamp":1625342560000},"page":"2063-2068","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Coinfection pulmonary mucormycosis and aspergillosis with disseminated mucormycosis involving gastrointestinalin in an acute B-lymphoblastic leukemia patient"],"prefix":"10.1007","volume":"52","author":[{"given":"Zhi-min","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan-lan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6701-5755","authenticated-orcid":false,"given":"Liang","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong-ju","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin-bin","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,3]]},"reference":[{"key":"554_CR1","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.3201\/eid2007.140087","volume":"20","author":"D Bitar","year":"2014","unstructured":"Bitar D, Lortholary O, Le Strat Y, Nicolau J, Coignard B, Tattevin P et al (2014) Population based analysis of invasive fungal infections, france, 2001\u20132010. Emerg Infect Dis 20:1149\u20131155","journal-title":"Emerg Infect Dis"},{"key":"554_CR2","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1186\/s12879-016-2005-1","volume":"16","author":"ZD Pana","year":"2016","unstructured":"Pana ZD, Seidel D, Skiada A, Groll AH, Petrikkos G, Cornely OA et al (2016) Invasive mucormycosis in children: an epidemiologic study in European and non-European countries based on two registries. BMC Infect Dis 16:667","journal-title":"BMC Infect Dis"},{"key":"554_CR3","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.mib.2017.10.010","volume":"40","author":"AS Ibrahim","year":"2017","unstructured":"Ibrahim AS, Voelz K (2017) The mucormycete-host interface. Curr Opin Microbiol 40:40\u201345","journal-title":"Curr Opin Microbiol"},{"issue":"Suppl 3","key":"554_CR4","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1111\/myc.12232","volume":"57","author":"AS Ibrahim","year":"2014","unstructured":"Ibrahim AS (2014) Host-iron assimilation: pathogenesis and novel therapies of mucormycosis. Mycoses 57(Suppl 3):13\u201317","journal-title":"Mycoses"},{"issue":"Suppl 1","key":"554_CR5","doi-asserted-by":"publisher","first-page":"S23","DOI":"10.1093\/cid\/cir866","volume":"54","author":"G Petrikkos","year":"2012","unstructured":"Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP (2012) Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 54(Suppl 1):S23-34","journal-title":"Clin Infect Dis"},{"key":"554_CR6","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1093\/cid\/cis749","volume":"55","author":"T Warkentien","year":"2012","unstructured":"Warkentien T, Rodriguez C, Lloyd B, Wells J, Weintrob A, Dunne JR et al (2012) Invasive mold infections following combat-related injuries. Clin Infect Dis 55:1441\u20131449","journal-title":"Clin Infect Dis"},{"key":"554_CR7","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1111\/j.1469-0691.2010.03456.x","volume":"17","author":"A Skiada","year":"2011","unstructured":"Skiada A, Pagano L, Groll A, Zimmerli S, Dupont B, Lagrou K et al (2011) Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007. Clin Microbiol Infect 17:1859\u20131867","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl 1","key":"554_CR8","doi-asserted-by":"publisher","first-page":"S35","DOI":"10.1093\/cid\/cir880","volume":"54","author":"F Lanternier","year":"2012","unstructured":"Lanternier F, Dannaoui E, Morizot G, Elie C, Garcia-Hermoso D, Huerre M et al (2012) A global analysis of mucormycosis in France: the RetroZygo study (2005\u20132007). Clin Infect Dis 54(Suppl 1):S35-43","journal-title":"Clin Infect Dis"},{"issue":"Suppl 3","key":"554_CR9","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1111\/myc.12247","volume":"57","author":"NN Klimko","year":"2014","unstructured":"Klimko NN, Khostelidi SN, Volkova AG, Popova MO, Bogomolova TS, Zuborovskaya LS et al (2014) Mucormycosis in haematological patients: case report and results of prospective study in Saint Petersburg, Russia. Mycoses 57(Suppl 3):91\u201396","journal-title":"Mycoses"},{"key":"554_CR10","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1007\/s11046-017-0167-z","volume":"182","author":"YH Li","year":"2017","unstructured":"Li YH, Sun P, Guo JC (2017) Clinical analysis of diabetic combined pulmonary mucormycosis. Mycopathologia 182:1111\u20131117","journal-title":"Mycopathologia"},{"key":"554_CR11","doi-asserted-by":"publisher","first-page":"5018","DOI":"10.1128\/AAC.00536-11","volume":"55","author":"SP Hammond","year":"2011","unstructured":"Hammond SP, Baden LR, Marty FM (2011) Mortality in hematologic malignancy and hematopoietic stem cell transplant patients with mucormycosis, 2001 to 2009. Antimicrob Agents Chemother 55:5018\u20135021","journal-title":"Antimicrob Agents Chemother"},{"key":"554_CR12","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1186\/1471-2334-14-310","volume":"14","author":"MD Zilberberg","year":"2014","unstructured":"Zilberberg MD, Shorr AF, Huang H, Chaudhari P, Paly VF, Menzin J (2014) Hospital days, hospitalization costs, and inpatient mortality among patients with mucormycosis: a retrospective analysis of US hospital discharge data. BMC Infect Dis 14:310\u2013319","journal-title":"BMC Infect Dis"},{"key":"554_CR13","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.mmcr.2012.07.003","volume":"1","author":"M Martinello","year":"2012","unstructured":"Martinello M, Nelson A, Bignold L, Shaw D (2012) \u201cWe are what we eat!\u201d Invasive intestinal mucormycosis: a case report and review of literature. Med Mycol Case Rep 1:52\u201355","journal-title":"Med Mycol Case Rep"},{"key":"554_CR14","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1111\/myc.12419","volume":"58","author":"MV Dioverti","year":"2015","unstructured":"Dioverti MV, Cawcutt KA, Abidi M, Sohail MR, Walker RC, Osmon DR (2015) Gastrointestinal mucormycosis in immunocompromised hosts. Mycoses 58:714\u2013718","journal-title":"Mycoses"},{"issue":"Suppl 1","key":"554_CR15","doi-asserted-by":"publisher","first-page":"S16","DOI":"10.1093\/cid\/cir865","volume":"54","author":"AS Ibrahim","year":"2012","unstructured":"Ibrahim AS, Spellberg B, Walsh TJ, Kontoyiannis DP (2012) Pathogenesis of mucormycosis. Clin Infect Dis 54(Suppl 1):S16\u2013S22","journal-title":"Clin Infect Dis"},{"key":"554_CR16","unstructured":"Clinical and Laboratory Standards Institute (2008) Reference method for broth dilution antifungal susceptibility testing of filamentous fungi. 2nd ed. CLSI document M38-A2. Clinical and Laboratory Standards Institute, Wayne"},{"key":"554_CR17","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s11046-016-0021-8","volume":"181","author":"M Chermetz","year":"2016","unstructured":"Chermetz M, Gobbo M, Rupel K, Ottaviani G, Tirelli G, Bussani R et al (2016) Combined orofacial aspergillosis and mucormycosis: fatal complication of a recurrent paediatric glioma-case report and review of literature. Mycopathologia 181:723\u2013733","journal-title":"Mycopathologia"},{"key":"554_CR18","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1086\/432579","volume":"41","author":"MM Roden","year":"2005","unstructured":"Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL et al (2005) Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 41:634\u2013653","journal-title":"Clin Infect Dis"},{"key":"554_CR19","doi-asserted-by":"publisher","first-page":"72","DOI":"10.3109\/13693786.2012.690107","volume":"51","author":"V Petraitis","year":"2013","unstructured":"Petraitis V, Petraitiene R, Antachopoulos C, Hughes JE, Cotton MP, Kasai M et al (2013) Increased virulence of Cunninghamella bertholletiae in experimental pulmonary mucormycosis: correlation with circulating molecular biomarkers, sporangiospore germination and hyphal metabolism. Med Mycol 51:72\u201382","journal-title":"Med Mycol"},{"key":"554_CR20","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jiph.2012.08.004","volume":"6","author":"P Goel","year":"2013","unstructured":"Goel P, Jain V, Sengar M, Mohta A, Das P, Bansal P (2013) Gastrointestinal mucormycosis: a success story and appraisal of concepts. J Infect Public Health 6:58\u201361","journal-title":"J Infect Public Health"},{"key":"554_CR21","doi-asserted-by":"publisher","first-page":"e6360","DOI":"10.1097\/MD.0000000000006360","volume":"96","author":"M Sun","year":"2017","unstructured":"Sun M, Hou X, Wang X, Chen G, Zhao Y (2017) Gastrointestinal mucormycosis of the jejunum in an immunocompetent patient. Medicine (Baltimore) 96:e6360","journal-title":"Medicine (Baltimore)"},{"key":"554_CR22","doi-asserted-by":"publisher","first-page":"2587","DOI":"10.1128\/AAC.00452-07","volume":"51","author":"NG Almyroudis","year":"2007","unstructured":"Almyroudis NG, Sutton DA, Fothergill AW, Rinaldi MG, Kusne S (2007) In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents. Antimicrob Agents Chemother 51:2587\u20132590","journal-title":"Antimicrob Agents Chemother"},{"key":"554_CR23","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1128\/AAC.01467-08","volume":"53","author":"A Alastruey-Izquierdo","year":"2009","unstructured":"Alastruey-Izquierdo A, Castelli MV, Cuesta I, Monzon A, Cuenca-Estrella M, Rodriguez-Tudela JL (2009) Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers. Antimicrob Agents Chemother 53:1686\u20131689","journal-title":"Antimicrob Agents Chemother"},{"key":"554_CR24","doi-asserted-by":"publisher","first-page":"4550","DOI":"10.1128\/AAC.00786-10","volume":"54","author":"FJ Pastor","year":"2010","unstructured":"Pastor FJ, Ru\u00edz-Cendoya M, Pujol I, Mayayo E, Sutton DA, Guarro J (2010) In vitro and In vivo antifungal susceptibilities of the Mucoralean fungus Cunninghamella. Antimicrob Agents Chemother 54:4550\u20134555","journal-title":"Antimicrob Agents Chemother"},{"key":"554_CR25","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1128\/AAC.04435-14","volume":"59","author":"A Espinel-Ingroff","year":"2015","unstructured":"Espinel-Ingroff A, Chakrabarti A, Chowdhary A, Cordoba S, Dannaoui E, Dufresne P et al (2015) Multicenter evaluation of MIC distributions for epidemiologic cutoff value definition to detect amphotericin B, posaconazole, and itraconazole resistance among the most clinically relevant species of Mucorales. Antimicrob Agents Chemother 59:1745\u20131750","journal-title":"Antimicrob Agents Chemother"},{"key":"554_CR26","volume-title":"Performance standards for antifungal susceptibility testing of filamentous fungi. M61","author":"Clinical and Laboratory Standards Institute","year":"2020","unstructured":"Clinical and Laboratory Standards Institute (2020) Performance standards for antifungal susceptibility testing of filamentous fungi. M61, 2nd edn. Clinical and Laboratory Standards Institute, Wayne","edition":"2"},{"issue":"Suppl 5","key":"554_CR27","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1111\/j.1469-0691.2009.02983.x","volume":"15","author":"E Dannaoui","year":"2009","unstructured":"Dannaoui E (2009) Molecular tools for identification of zygomycetes and the diagnosis of zygomycosis. Clin Microbiol Infect 15(Suppl 5):66\u201370","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl 3","key":"554_CR28","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/1469-0691.12371","volume":"20","author":"OA Cornely","year":"2014","unstructured":"Cornely OA, Arikan-Akdagli S, Dannaoui E, Groll AH, Lagrou K, Chakrabarti A et al (2014) ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormycosis 2013. Clin Microbiol Infect 20(Suppl 3):5\u201326","journal-title":"Clin Microbiol Infect"},{"key":"554_CR29","doi-asserted-by":"publisher","first-page":"433","DOI":"10.3324\/haematol.2016.152900","volume":"102","author":"F Tissot","year":"2017","unstructured":"Tissot F, Agrawal S, Pagano L, Petrikkos G, Groll AH, Skiada A et al (2017) ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients. Haematologica 102:433\u2013444","journal-title":"Haematologica"},{"key":"554_CR30","doi-asserted-by":"publisher","first-page":"S93","DOI":"10.1093\/mmy\/myx101","volume":"56","author":"A Skiada","year":"2018","unstructured":"Skiada A, Lass-Floerl C, Klimko N, Ibrahim A, Roilides E, Petrikkos G (2018) Challenges in the diagnosis and treatment of mucormycosis. Med Mycol 56:S93\u2013S101","journal-title":"Med Mycol"},{"key":"554_CR31","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1007\/s11046-017-0149-1","volume":"182","author":"H Ota","year":"2017","unstructured":"Ota H, Yamamoto H, Kimura M, Araoka H, Fujii T, Umeyama T et al (2017) Successful treatment of pulmonary mucormycosis caused by Cunninghamella bertholletiae with high-dose liposomal amphotericin B (10 mg\/kg\/day) followed by a lobectomy in cord blood transplant recipients. Mycopathologia 182:847\u2013853","journal-title":"Mycopathologia"}],"container-title":["Brazilian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-021-00554-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s42770-021-00554-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-021-00554-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T22:52:49Z","timestamp":1744152769000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s42770-021-00554-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,3]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["554"],"URL":"https:\/\/doi.org\/10.1007\/s42770-021-00554-8","relation":{},"ISSN":["1517-8382","1678-4405"],"issn-type":[{"value":"1517-8382","type":"print"},{"value":"1678-4405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,3]]},"assertion":[{"value":"1 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 June 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}