{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:29:21Z","timestamp":1790047761664,"version":"4.0.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Braz J Microbiol"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1007\/s42770-024-01334-w","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T03:17:31Z","timestamp":1714965451000},"page":"1189-1203","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["In vitro effects of alginate lyase SG4\u2009+\u2009produced by Paenibacillus lautus alone and combined with antibiotics on biofilm formation by mucoid Pseudomonas aeruginosa"],"prefix":"10.1007","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-0024","authenticated-orcid":false,"given":"Kriti","family":"Kanwar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepika","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harjodh","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohinder","family":"Pal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajneesh","family":"Bandhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wamik","family":"Azmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"key":"1334_CR1","doi-asserted-by":"publisher","first-page":"1008010","DOI":"10.3389\/fchem.2022.1008010","volume":"10","author":"Z Zheng","year":"2022","unstructured":"Zheng Z, Dai A, Liu Y, Li T (2022) Sustainable alginate lyases catalysed degradation of biobased carbohydrates. Front Chem 10:1008010. https:\/\/doi.org\/10.3389\/fchem.2022.1008010","journal-title":"Front Chem"},{"key":"1334_CR2","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1093\/aob\/mcu096","volume":"114","author":"E Deniaud-Bou\u00ebt","year":"2014","unstructured":"Deniaud-Bou\u00ebt E, Kervarec N, Michel G, Tonon T, Kloareg B, Herv\u00e9 C (2014) Chemical and enzymatic fractionation of cell walls from Fucales: insights into the structure of the extracellular matrix of brown algae. Ann Bot 114:1203\u20131216","journal-title":"Ann Bot"},{"key":"1334_CR3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2174\/138920207780833810","volume":"8","author":"AN Muhammadi","year":"2007","unstructured":"Muhammadi AN (2007) Genetics of bacterial alginate: alginate genes distribution, organization and biosynthesis in bacteria. Curr Genomics 8:191\u2013202","journal-title":"Curr Genomics"},{"key":"1334_CR4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.progpolymsci.2011.06.003","volume":"37","author":"KY Lee","year":"2012","unstructured":"Lee KY, Mooney DJ (2012) Alginate: properties and biomedical applications. Prog Polymer Sci 37:106\u2013126","journal-title":"Prog Polymer Sci"},{"key":"1334_CR5","doi-asserted-by":"crossref","first-page":"184","DOI":"10.3390\/md18040184","volume":"18","author":"J Yang","year":"2020","unstructured":"Yang J, Cui D, Chen D, Chen W, Ma S, Shen H (2020) Purification and Characterization of a novel endolytic alginate lyase from Microbulbifer sp. SH-1 and its agricultural application. Marine Drugs 18:184","journal-title":"Marine Drugs"},{"key":"1334_CR6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1080\/21655979.2015.1030543","volume":"6","author":"B Zhu","year":"2015","unstructured":"Zhu B, Yin H (2015) Alginate lyase: Review of major sources and classification, properties, structure-function analysis and applications. Bioengineered 6:125\u2013131","journal-title":"Bioengineered"},{"key":"1334_CR7","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.3390\/molecules27113375","volume":"27","author":"N Barzkar","year":"2022","unstructured":"Barzkar N, Sheng R, Sohail M, Jahromi ST, Babich O, Sukhikh S, Nahavandi R (2022) Alginate lyases from marine bacteria: an enzyme ocean for sustainable future. Molecules 27:3375","journal-title":"Molecules"},{"key":"1334_CR8","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s12257-021-0246-3","volume":"27","author":"NTM Le","year":"2022","unstructured":"Le NTM, Le VV, Shin D et al (2022) Growth-promoting Effect of Alginate Oligosaccharides on Rhodobacter sphaeroides. Biotechnol Bioproc 27:99\u2013104","journal-title":"Biotechnol Bioproc"},{"key":"1334_CR9","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.tim.2013.06.002","volume":"21","author":"T Bjarnsholt","year":"2013","unstructured":"Bjarnsholt T, Alhede M, Alhede M, Eickhardt-Sorensen SR, Moser C, Kuhl M (2013) The in vivo biofilm. Trends Microbiol 21:466\u201374","journal-title":"Trends Microbiol"},{"key":"1334_CR10","doi-asserted-by":"crossref","first-page":"9390","DOI":"10.1038\/s41598-020-66293-2","volume":"10","author":"N Blanco-Cabra","year":"2020","unstructured":"Blanco-Cabra N, Paetzold B, Ferrar T, Mazzolini R, Torrents E, Serrano L, LLuch SM (2020) Characterization of different alginate lyases for dissolving Pseudomonas aeruginosa biofilms. Sci Rep 10:9390","journal-title":"Sci Rep"},{"key":"1334_CR11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12575-019-0106-0","volume":"21","author":"L Thieme","year":"2019","unstructured":"Thieme L, Hartung A, Tramm K, Klinger-Strobel M, Jandt KD, Makarewicz O, Pletz MW (2019) MBEC Versus MBIC: the lack of differentiation between biofilm reducing and inhibitory effects as a current problem in biofilm methodology. Biol Proced Online 21:18","journal-title":"Biol Proced Online"},{"key":"1334_CR12","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jcf.2020.04.006","volume":"20","author":"MD Said","year":"2021","unstructured":"Said MD, John RR, Zhenyu C (2021) Disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate lyase enhances pathogen eradication by antibiotics. J Cyst Fibros 20:264\u2013270","journal-title":"J Cyst Fibros"},{"key":"1334_CR13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.micro.54.1.289","volume":"54","author":"TY Wong","year":"2000","unstructured":"Wong TY, Preston LA, Schiller NL (2000) Alginate lyase: review of major sources and enzyme characteristics, structure-function analysis, biological roles, and applications. Ann Rev Microbiol 54:289\u2013340","journal-title":"Ann Rev Microbiol"},{"key":"1334_CR14","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3390\/polym14040661","volume":"14","author":"R Saberi Riseh","year":"2022","unstructured":"Saberi Riseh R, Gholizadeh Vazvani M, Ebrahimi-Zarandi M, Skorik YA (2022) Alginate-induced disease resistance in plants. Polymers 14:661","journal-title":"Polymers"},{"key":"1334_CR15","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3390\/md20060388","volume":"20","author":"H Huang","year":"2022","unstructured":"Huang H, Zheng Z, Zou X, Wang Z, Gao R, Zhu J, Hu Y, Bao S (2022) Genome Analysis of a novel polysaccharide-degrading bacterium Paenibacillus algicola and determination of alginate lyases. Mar Drugs 20:388","journal-title":"Mar Drugs"},{"key":"1334_CR16","first-page":"56","volume":"12","author":"K Kanwar","year":"2020","unstructured":"Kanwar K, Azmi W (2020) Alginate lyase enzyme from Paenibacillus lautus as potential candidate for depolymerization of alginate-to-alginate oligosaccharides. T Carb Res 12:56\u201362","journal-title":"T Carb Res"},{"key":"1334_CR17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0141-0229(95)00155-7","volume":"18","author":"JA Milner","year":"1996","unstructured":"Milner JA, Martin DJ, Smith A (1996) Oxygen transfer conditions in the production of alpha-amylase by Bacillus amyloliquefaciens. Enzyme Microb Technol 18:507\u2013512","journal-title":"Enzyme Microb Technol"},{"key":"1334_CR18","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/biomet\/33.4.305","volume":"33","author":"RL Plackett","year":"1946","unstructured":"Plackett RL, Burman JP (1946) The Design of optimum Multifactorial experiments. Biometrika 33:305\u2013325","journal-title":"Biometrika"},{"key":"1334_CR19","first-page":"92","volume-title":"Protein methods","author":"DM Bollag","year":"1991","unstructured":"Bollag DM, Edelstein SJ (1991) Gel electrophoresis under denaturing conditions. In: Bollag DM, Edelstein SJ (eds) Protein methods. John Wiley & Sons, New York, pp 92\u2013127"},{"key":"1334_CR20","doi-asserted-by":"crossref","first-page":"4693","DOI":"10.3390\/md12084693","volume":"12","author":"A Inoue","year":"2014","unstructured":"Inoue A, Takadono K, Nishiyama R, Tajima K, Kobayashi T, Ojima T (2014) Characterization of an Alginate Lyase, FlAlyA, from Flavobacterium sp. Strain UMI-01 and Its Expression in Escherichia coli. Mar Drugs 12:4693\u20134712","journal-title":"Mar Drugs"},{"key":"1334_CR21","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1472-765X.2004.01513.x","volume":"38","author":"S Stepanovic","year":"2004","unstructured":"Stepanovic S, Cirkovic I, Ranin L, Svabic-Vlahovic M (2004) Biofilm formation by Salmonella spp. and Listeria monocytogenes on plastic surface. Lett Appl Microbiol 38:428\u2013432","journal-title":"Lett Appl Microbiol"},{"key":"1334_CR22","first-page":"735","volume":"57","author":"A Cruz","year":"2011","unstructured":"Cruz A, Xicohtencatl-Cortes J, Gonz\u00e1lez-Pedrajo B, Bobadilla M, Eslava C, Rosas I (2011) Virulence trait in Cronobacter spp. isolated from different sources. J Microbiol 57:735\u2013744","journal-title":"J Microbiol"},{"key":"1334_CR23","first-page":"212","volume":"551","author":"Y Hu","year":"2018","unstructured":"Hu Y, Li M, Zhang M, Jin Y (2018) Inhalation treatment of idiopathic pulmonary fibrosis with curcumin large porous microparticles. I J Pharma 551:212\u2013222","journal-title":"I J Pharma"},{"key":"1334_CR24","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.3390\/ijms24044030","volume":"24","author":"E Balducci","year":"2023","unstructured":"Balducci E, Papi F, Capialbi DE, Del Bino L (2023) Polysaccharides\u2019 structures and functions in biofilm architecture of antimicrobial-resistant (AMR) pathogens. Int J Mol Sci 24:4030","journal-title":"Int J Mol Sci"},{"key":"1334_CR25","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.biortech.2016.12.073","volume":"227","author":"N Asadi","year":"2017","unstructured":"Asadi N, Zilouei H (2017) Optimization of organosolv pretreatment of rice straw for enhanced biohydrogen production using Enterobacter aerogenes. Bioresour Technol 227:335\u2013344","journal-title":"Bioresour Technol"},{"key":"1334_CR26","unstructured":"Sharma D, Manhas RK (2013) Application of Plackett\u2013Burman experimental design and Box and Wilson design to improve broad-spectrum antimicrobial compound. 12: 386-396"},{"issue":"5","key":"1334_CR27","doi-asserted-by":"crossref","first-page":"e01718","DOI":"10.1016\/j.heliyon.2019.e01718","volume":"5","author":"S Sondhi","year":"2019","unstructured":"Sondhi S, Saini K (2019) Response surface-based optimization of laccase production from Bacillus sp. MSK-01 using fruit juice waste as an effective substrate. Heliyon 5(5):e01718","journal-title":"Heliyon"},{"key":"1334_CR28","doi-asserted-by":"publisher","first-page":"48","DOI":"10.6091\/.21.1.48","volume":"1","author":"H Tavafi","year":"2017","unstructured":"Tavafi H, Abdi-Ali A, Ghadam P, Gharavi S (2017) Screening of alginate lyase-producing bacteria and optimization of media compositions for extracellular alginate lyase production. Iran Biomed J 1:48\u201356. https:\/\/doi.org\/10.6091\/.21.1.48","journal-title":"Iran Biomed J"},{"key":"1334_CR29","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s13068-020-01738-4","volume":"13","author":"L Tang","year":"2020","unstructured":"Tang L, Wang Y, Gao S, Wu H, Wang D, Yu W, Han F (2020) Biochemical characteristics and molecular mechanism of an exo-type alginate lyase VxAly7D and its use for the preparation of unsaturated monosaccharides. Biotechnol Biofuels 13:99","journal-title":"Biotechnol Biofuels"},{"key":"1334_CR30","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/13102818.2022.2071635","volume":"36","author":"BR Mohapatra","year":"2022","unstructured":"Mohapatra BR (2022) Fermentation medium optimization, molecular modelling and docking analysis of the alginate lyase of a novel Pseudomonas sp. LB56 isolated from seaweed waste. Biotechnol Biotechnol Equ 36:281\u2013291","journal-title":"Biotechnol Biotechnol Equ"},{"key":"1334_CR31","doi-asserted-by":"crossref","first-page":"4937","DOI":"10.1038\/s41598-019-41351-6","volume":"9","author":"A Inoue","year":"2019","unstructured":"Inoue A, Ojima T (2019) Functional identification of alginate lyase from the brown alga Saccharina japonica. Sci Rep 9:4937","journal-title":"Sci Rep"},{"key":"1334_CR32","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1080\/09168451.2016.1232154","volume":"80","author":"H Yagi","year":"2016","unstructured":"Yagi H, Fujise A, Itabashi N, Ohshiro T (2016) Purification and characterization of a novel alginate lyase from the marine bacterium Cobetia sp. NAP1 isolated from brown algae. Biosci Biotechnol Biochem 80:2338\u20132346","journal-title":"Biosci Biotechnol Biochem"},{"key":"1334_CR33","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3390\/md16010030","volume":"161","author":"X Zhu","year":"2018","unstructured":"Zhu X, Li X, Shi H, Zhou J, Tan Z, Yuan M, Yao P, Liu X (2018) Characterization of a novel alginate lyase from marine bacterium Vibrio furnissii H1. Mar Drugs 161:30","journal-title":"Mar Drugs"},{"key":"1334_CR34","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3390\/md16030086","volume":"16","author":"P Chen","year":"2018","unstructured":"Chen P, Zhu Y, Men Y, Zeng Y, Sun Y (2018) Purification and characterization of a novel alginate lyase from the marine bacterium Bacillus sp. alg07. Mar Drugs 16:86","journal-title":"Mar Drugs"},{"key":"1334_CR35","unstructured":"Weiner RM, Hutcheson SW, Abdel-Hafez AAW, Howard M, Taylor LE and Ekborg NA (2008) Alginases, systems containing alginases and methods of cloning, purifying and\/or utilizing alginases. U.S. Patent No. 7,439,034"},{"key":"1334_CR36","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.carbpol.2006.03.004","volume":"66","author":"C Bandaiphet","year":"2006","unstructured":"Bandaiphet C, Prasertsan P (2006) Effect of aeration and agitation rates and scale-up on oxygen transfer coefficient, KLa in exopolysaccharide production from Enterobacter cloacae WD7. Carbohydr Polym 66:216\u2013228","journal-title":"Carbohydr Polym"},{"key":"1334_CR37","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s002530051377","volume":"51","author":"S Shioya","year":"1999","unstructured":"Shioya S, Morikawa M, Kajihara Y, Shimizu H (1999) Optimization of agitation and aeration conditions for maximum virginiamycin production. Appl Microbiol Biotechnol 51:164\u2013169","journal-title":"Appl Microbiol Biotechnol"},{"key":"1334_CR38","first-page":"41","volume":"7","author":"D Nisha","year":"2018","unstructured":"Nisha D, Abhinay KS, Wamik A (2018) Analysis of the combined effects of aeration and agitation rate on dextransucrase production by Leuconostoc lactis KU665298 in a laboratory fermenter using response surface methodology. J Microbiol Biotechnol 7:41\u201352","journal-title":"J Microbiol Biotechnol"},{"key":"1334_CR39","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1002\/(SICI)1097-0290(19980120)57:2<198::AID-BIT8>3.0.CO;2-I","volume":"57","author":"A Amanullah","year":"1998","unstructured":"Amanullah A, Tuttiett B, Nienow AW (1998) Agitation speed and dissolved oxygen effects in xanthan fermentations. Biotechnol Bioeng 57:198\u2013210","journal-title":"Biotechnol Bioeng"},{"key":"1334_CR40","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.955286","volume":"13","author":"R Yin","year":"2022","unstructured":"Yin R, Cheng J, Wang J, Li P, Lin J (2022) Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies. Front Microbiol 13:955286. https:\/\/doi.org\/10.3389\/fmicb.2022.955286","journal-title":"Front Microbiol"},{"issue":"5","key":"1334_CR41","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.3390\/ijms24054740","volume":"24","author":"M Char\u0119za","year":"2023","unstructured":"Char\u0119za M, Przygrodzka K, Zywicka A, Grygorcewicz B, Sobolewski P, Mozia S, Smiglak M, Drozd R (2023) Enhancement of inhibition of the Pseudomonas sp. biofilm formation on bacterial cellulose-based wound dressing by the combined action of alginate lyase and gentamicin. Int J Mol Sci 24(5):4740","journal-title":"Int J Mol Sci"},{"key":"1334_CR42","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3390\/md17050307","volume":"17","author":"SM Daboor","year":"2019","unstructured":"Daboor SM, Raudonis R, Cohen A, Rhode JR, Cheng Z (2019) Marine bacteria, a source for alginolytic enzyme to disrupt Pseudomonas aeruginosa biofilms. Mar Drugs 17:307","journal-title":"Mar Drugs"},{"key":"1334_CR43","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.116625","volume":"246","author":"M Szyma\u0144ska","year":"2020","unstructured":"Szyma\u0144ska M, Karakulska J, Sobolewski P, Kowalska U, Grygorcewicz B, B\u00f6ttcher D, Bornscheuer UT, Drozd R (2020) Glycoside hydrolase (PelAh) immobilization prevents Pseudomonas aeruginosa biofilm formation on cellulose-based wound dressing. Carbohydr Polym 246:116625","journal-title":"Carbohydr Polym"},{"key":"1334_CR44","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1046\/j.1365-2672.1998.00319.x","volume":"84","author":"A Nakagawa","year":"1998","unstructured":"Nakagawa A, Ozaki T, Chubachi K, Hosoyama T, Okubo T, Iyobe S, Suzuki T (1998) An effective method for isolating alginate lyase-producing Bacillus sp. ATB-1015 strain and purification and characterization of the lyase. J Appl Microbiol 84:328\u2013335","journal-title":"J Appl Microbiol"},{"key":"1334_CR45","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1128\/AEM.03460-14","volume":"81","author":"AH Badur","year":"2015","unstructured":"Badur AH, Jagtap SS, Yalamanchili G, Lee JK, Zhao H, Rao CV (2015) Alginate lyases from alginate-degrading Vibrio splendidus 12B01 are endolytic. Appl Environ Microbiol 81:1865\u20131873","journal-title":"Appl Environ Microbiol"},{"key":"1334_CR46","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3390\/md16050158","volume":"11","author":"H Li","year":"2018","unstructured":"Li H, Wang S, Zhang Y, Chen L (2018) High-Level Expression of a Thermally Stable Alginate Lyase Using Pichia pastoris, Characterization and Application in Producing Brown Alginate Oligosaccharide. Mar Drugs 11:158","journal-title":"Mar Drugs"},{"key":"1334_CR47","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3390\/md18060305","volume":"11","author":"S Yang","year":"2020","unstructured":"Yang S, Liu Z, Fu X, Zhu C, Kong Q, Yang M, Mou H (2020) Expression and Characterization of an Alginate Lyase and Its Thermostable Mutant in Pichia pastoris. Mar Drugs 11:305","journal-title":"Mar Drugs"},{"key":"1334_CR48","doi-asserted-by":"crossref","first-page":"4039","DOI":"10.3390\/foods12214039","volume":"12","author":"Q Liang","year":"2023","unstructured":"Liang Q, Huang Y, Liu Z, Xiao M, Ren X, Liu T, Li H, Yu D, Wang Y, Zhu C (2023) A Recombinant Alginate Lyase Algt1 with Potential in Preparing Alginate Oligosaccharides at High-Concentration Substrate. Foods 12:4039","journal-title":"Foods"}],"container-title":["Brazilian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-024-01334-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s42770-024-01334-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-024-01334-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T02:23:56Z","timestamp":1717640636000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s42770-024-01334-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,6]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1334"],"URL":"https:\/\/doi.org\/10.1007\/s42770-024-01334-w","relation":{},"ISSN":["1517-8382","1678-4405"],"issn-type":[{"value":"1517-8382","type":"print"},{"value":"1678-4405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,6]]},"assertion":[{"value":"8 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The manuscript does not contain experiments using animals and it does not contain human studies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical issues"}},{"value":"The authors have no conflicts of interest to declare.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}