{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T18:00:47Z","timestamp":1781632847702,"version":"3.54.5"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005742","name":"Universidade Federal De Goi\u00e1s","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005742","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Braz J Microbiol"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Capybara (\n                    <jats:italic>Hydrochoerus hydrochaeris<\/jats:italic>\n                    ), the largest rodent in the world, are animals native to Brazil that are increasingly adapting to urban environments, which raises concerns for One Health, including the risk of zoonotic diseases such as Brazilian Spotted Fever. Moreover, increased interaction between humans and capybaras can lead to accidents involving injuries and infections. This study aimed to characterize the oral microbiota of healthy capybaras in a peri-urban environment in Goi\u00e1s state, midwestern region of Brazil. Oral clinical examinations were performed, and subgingival biofilm samples were collected from eight capybaras captured on the campus of the Universidade Federal de Goi\u00e1s. Sequencing of the V4 region of the 16\u00a0S ribosomal RNA gene revealed a predominance of the phyla Firmicutes (48.06%), Proteobacteria (22.07%), Actinobacteriota (11.56%), and Bacteroidota (7.14%). The most abundant genera were\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    (36.68%),\n                    <jats:italic>Rothia<\/jats:italic>\n                    (6.47%), and\n                    <jats:italic>Weissella<\/jats:italic>\n                    (2.02%). Microbial composition varied among individuals, with notably lower diversity in the only juvenile evaluated. This interindividual variability may be influenced by dietary and environmental factors. Genera frequently associated with periodontal disease, such as\n                    <jats:italic>Fusobacterium<\/jats:italic>\n                    and\n                    <jats:italic>Bacteroides<\/jats:italic>\n                    , were detected at low prevalence. The presence of\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    ,\n                    <jats:italic>Rothia<\/jats:italic>\n                    , and\n                    <jats:italic>Klebsiella<\/jats:italic>\n                    suggests the pathogenic potential of these microorganisms for humans and animals, especially in the event of accidents. This study is the first to evaluate the oral microbiota of capybaras and opens an important field of research within the One Health framework. These findings reinforce the importance of microbiological monitoring of synanthropic wildlife for both public health and the oral health of the species.\n                  <\/jats:p>","DOI":"10.1007\/s42770-026-01871-6","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T23:42:46Z","timestamp":1770075766000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First characterization of the oral microbiota of capybaras (Hydrochoerus hydrochaeris) in Brazil: insights into one health risks"],"prefix":"10.1007","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1606-1708","authenticated-orcid":false,"given":"Tamires Ataides","family":"Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7284-5801","authenticated-orcid":false,"given":"Lucianne Cardoso","family":"Neves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8141-4616","authenticated-orcid":false,"given":"Warley Vieira de Freitas","family":"Paula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1107-3913","authenticated-orcid":false,"given":"Bianca Barbara Fonseca","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2267-3727","authenticated-orcid":false,"given":"Diego Ortiz","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1964-8101","authenticated-orcid":false,"given":"C\u00edntia Pelegrineti","family":"Targueta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8856-7164","authenticated-orcid":false,"given":"Fl\u00e1via Regina Florencio","family":"Athayde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9023-0007","authenticated-orcid":false,"given":"Mariana Pires de Campos","family":"Telles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0566-7595","authenticated-orcid":false,"given":"Iveraldo dos Santos","family":"Dutra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3817-225X","authenticated-orcid":false,"given":"Felipe da Silva","family":"Krawczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1209-8709","authenticated-orcid":false,"given":"Ana Carolina","family":"Borsanelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"1871_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2307\/3503784","volume":"264","author":"A Mones","year":"1986","unstructured":"Mones A, Ojasti J (1986) Hydrochoerus Hydrochaeris. Mamm Species 264:1\u20137. https:\/\/doi.org\/10.2307\/3503784","journal-title":"Mamm Species"},{"key":"1871_CR2","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1590\/S1519-69842006000200019","volume":"66","author":"LM Verdade","year":"2006","unstructured":"Verdade LM, Ferraz KMPMB (2006) Capybaras in an anthropogenic habitat in southeastern Brazil. Braz J Biol 66:371\u2013378. https:\/\/doi.org\/10.1590\/S1519-69842006000200019","journal-title":"Braz J Biol"},{"issue":"2","key":"1871_CR3","doi-asserted-by":"publisher","first-page":"54","DOI":"10.5902\/2179460X12560","volume":"35","author":"AR Almeida","year":"2013","unstructured":"Almeida AR, Biondi D, Filho ELAM (2013) Din\u00e2mica e biologia de Uma popula\u00e7\u00e3o de Capivaras Em ambiente antr\u00f3pico, Curitiba-PR. Cienc Nat 35(2):54\u201364. https:\/\/doi.org\/10.5902\/2179460X12560","journal-title":"Cienc Nat"},{"issue":"3","key":"1871_CR4","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1590\/1809-6891v15i319663","volume":"15","author":"AR Almeida","year":"2014","unstructured":"Almeida AR, Biondi D (2014) Area of use by Hydrochoerus hydrochaeris L. in an urban environment (portuguese). Cienc Anim Bras 15(3):369\u2013376. https:\/\/doi.org\/10.1590\/1809-6891v15i319663","journal-title":"Cienc Anim Bras"},{"issue":"1\/2","key":"1871_CR5","first-page":"99","volume":"47","author":"CJR Alho","year":"1987","unstructured":"Alho CJR, Campos ZMS, Gon\u00e7alves HC (1987) Ecologia de capivara (Hydrochoerus hydrochaeris, Rodentia) do Pantanal: - ii atividade, sazonalidade, uso do espa\u00e7o e manejo. Rev Bras Biol 47(1\/2):99\u2013110","journal-title":"Rev Bras Biol"},{"issue":"40","key":"1871_CR6","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1177\/089875649501200403","volume":"12","author":"DA Crossley","year":"1995","unstructured":"Crossley DA (1995) Clinical aspects of rodent dental anatomy. J Vet Dent 12(40):131\u2013135. https:\/\/doi.org\/10.1177\/089875649501200403","journal-title":"J Vet Dent"},{"issue":"5","key":"1871_CR7","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1111\/j.1439-0264.2006.00686.x","volume":"35","author":"FS Oliveira","year":"2006","unstructured":"Oliveira FS, Canola JC, Oliveira PT, P\u00e9cora JD, Capelli A (2006) Anatomoradiographic description of the teeth of Pacas bred in captivity (Agouti paca, Linnaeus, 1766). Anat Histol Embryol 35(5):316\u2013318. https:\/\/doi.org\/10.1111\/j.1439-0264.2006.00686.x","journal-title":"Anat Histol Embryol"},{"key":"1871_CR8","doi-asserted-by":"publisher","DOI":"10.22456\/1679-9216.89415","volume":"47","author":"MT Kihara","year":"2019","unstructured":"Kihara MT, Rocha TASS, Santos CCC, Fechis ADS, Alves ACA, Sasahara THC, Oliveira FS (2019) Anatomorradiographic description of the capybara\u00b4s teeth (Hydrochoerus hydrochaeris). Acta Sci Vet 47:1624. https:\/\/doi.org\/10.22456\/1679-9216.89415","journal-title":"Acta Sci Vet"},{"issue":"2","key":"1871_CR9","first-page":"311","volume":"35","author":"F Schitoskey","year":"1971","unstructured":"Schitoskey F (1971) Anomalies and pathological conditions in the skulls of nutria from Southern Louisiana. Extrait De Mammalia 35(2):311\u2013314","journal-title":"Extrait De Mammalia"},{"issue":"10","key":"1871_CR10","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/j.archoralbio.2004.02.015","volume":"49","author":"K Sone","year":"2004","unstructured":"Sone K, Koyasu K, Oda S (2004) Dental and skull anomalies in feral coypu, Myocastor coypus. Arch Oral Biol 49(10):849\u2013854. https:\/\/doi.org\/10.1016\/j.archoralbio.2004.02.015","journal-title":"Arch Oral Biol"},{"key":"1871_CR11","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.archoralbio.2004.09.010","volume":"50","author":"K Sone","year":"2005","unstructured":"Sone K, Koyasu K, Tanaka S, Oda S (2005) Effects of diet on the incidence of dental pathology in free living caviomorph rodents. Arch Oral Biol 50:323\u2013331. https:\/\/doi.org\/10.1016\/j.archoralbio.2004.09.010","journal-title":"Arch Oral Biol"},{"issue":"1","key":"1871_CR12","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1590\/S0103-90162003000100029","volume":"60","author":"KMPMB Ferraz","year":"2003","unstructured":"Ferraz KMPMB, Lechevalier M, Couto HTZ, Verdade LM (2003) Damage caused by capybaras in a corn field. Sci Agric 60(1):191\u2013194. https:\/\/doi.org\/10.1590\/S0103-90162003000100029","journal-title":"Sci Agric"},{"key":"1871_CR13","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/j.1365-2699.2006.01568.x","volume":"34","author":"KMPMB Ferraz","year":"2007","unstructured":"Ferraz KMPMB, Ferraz SFB, Moreira JR, Couto HTZ, Verdade LM (2007) Capybara (Hydrochoerus hydrochaeris) distribution in agroecosystems: a cross-scale habitat analysis. J Biogeogr 34:223\u2013230","journal-title":"J Biogeogr"},{"issue":"5","key":"1871_CR14","doi-asserted-by":"publisher","first-page":"101463","DOI":"10.1016\/j.ttbdis.2020.101463","volume":"11","author":"A Ram\u00edrez-Hern\u00e1ndez","year":"2020","unstructured":"Ram\u00edrez-Hern\u00e1ndez A, Uchoa F, Serpa MCA, Binder LC, Souza CE, LabrunaMB (2020) Capybaras (Hydrochoerus hydrochaeris) as amplifying hosts of Rickettsia rickettsii to Amblyomma sculptum ticks: evaluation during primary and subsequent exposures to R. rickettsii infection. Ticks Tick Borne Dis 11(5):101463. https:\/\/doi.org\/10.1016\/j.ttbdis.2020.101463","journal-title":"Ticks Tick Borne Dis"},{"key":"1871_CR15","doi-asserted-by":"publisher","unstructured":"Paula LGF, Nascimento RM, Franco AO, Szab\u00f3 MPJ, Labruna MB, Monteiro C, Krawczak FS (2022) Seasonal dynamics of Amblyomma sculptum: a review. Parasites Vectors 193(15). https:\/\/doi.org\/10.1186\/s13071-022-05311-w","DOI":"10.1186\/s13071-022-05311-w"},{"issue":"6","key":"1871_CR16","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.jemermed.2015.08.007","volume":"49","author":"CO Oliveira","year":"2015","unstructured":"Oliveira CO, Bernardes Filho F, Azulay-Abulafia L (2015) Capybara bites: report of human injury caused by a Hydrochoerus hydrochaeris. J Emerg Med 49(6):179\u2013182. https:\/\/doi.org\/10.1016\/j.jemermed.2015.08.007","journal-title":"J Emerg Med"},{"key":"1871_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/0037-8682-0043-2021","volume":"54","author":"AL Rossetto","year":"2021","unstructured":"Rossetto AL, Amarante LF, Rossetto AL, Junior VH (2021) Injuries and infection caused by capybara bites in a human. Rev Soc Bras Med Trop 54:1\u20132. https:\/\/doi.org\/10.1590\/0037-8682-0043-2021","journal-title":"Rev Soc Bras Med Trop"},{"issue":"2","key":"1871_CR18","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1099\/00222615-47-2-95","volume":"47","author":"EJC Goldstein","year":"1998","unstructured":"Goldstein EJC (1998) New horizons in the bacteriology, antimicrobial susceptibility and therapy of animal bite wounds. J Med Microbiol 47(2):95\u201397. https:\/\/doi.org\/10.1099\/00222615-47-2-95","journal-title":"J Med Microbiol"},{"issue":"1","key":"1871_CR19","doi-asserted-by":"publisher","DOI":"10.3390\/ani13010094","volume":"13","author":"LC Neves","year":"2023","unstructured":"Neves LC, Sousa-Paula LC, Dias SA, Silva BBF, Paula WVF, Paula LGF, Pereira BG, P\u00e1dua GT, Borsanelli AC, Cardoso ERN, Krawczak FS, Dantas-Torres F (2023) Detection of an undescribed Babesia sp. in capybaras and Amblyomma ticks in Central-Western Brazil. Animals 13(1):94. https:\/\/doi.org\/10.3390\/ani13010094","journal-title":"Animals"},{"key":"1871_CR20","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.936021","volume":"13","author":"AC Borsanelli","year":"2022","unstructured":"Borsanelli AC, Athayde FRF, Riggio MP, Brandt BW, Rocha FI, Jesus EC, Gaettir-Jardim J\u00fanior E, Schweitzer CM, Dutra IS (2022) Dysbiosis and predicted function of dental and ruminal microbiome associated with bovine periodontitis. Front Microbiol 13:936021. https:\/\/doi.org\/10.3389\/fmicb.2022.936021","journal-title":"Front Microbiol"},{"key":"1871_CR21","doi-asserted-by":"publisher","first-page":"4516","DOI":"10.1073\/pnas.1000080107","volume":"108","author":"JG Caporaso","year":"2011","unstructured":"Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Lozupone CA, Turnbaugh PJ et al (2011) Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci U S A 108:4516\u20134522. https:\/\/doi.org\/10.1073\/pnas.1000080107","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1871_CR22","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1038\/ismej.2012.8","volume":"6","author":"JG Caporaso","year":"2012","unstructured":"Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Huntley J, Fierer N et al (2012) Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J 6:1621\u20131624. https:\/\/doi.org\/10.1038\/ismej.2012.8","journal-title":"ISME J"},{"key":"1871_CR23","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1038\/nmeth.3869","volume":"13","author":"BJ Callahan","year":"2016","unstructured":"Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJ, Holmes SP (2016) DADA2: high-resolution sample inference from illumina amplicon data. Nat Methods 13:581\u2013583","journal-title":"Nat Methods"},{"key":"1871_CR24","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1093\/nar\/gks1219","volume":"41","author":"C Quast","year":"2013","unstructured":"Quast C, Pruesse E, Yilmaz P, Gerken J, Schweer T, Yarza P, Peplies J, Gl\u00f6ckner FO (2013) The SILVA ribossomal RNA gene database project: improved data processing and webbased tools. Nucleic Acids Res 41:590\u2013596","journal-title":"Nucleic Acids Res"},{"key":"1871_CR25","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2019","unstructured":"R Core Team (2019) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria"},{"issue":"4","key":"1871_CR26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061217","volume":"8","author":"PJ McMurdie","year":"2013","unstructured":"McMurdie PJ, Holmes S (2013) phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PLoS One 8(4):e61217. https:\/\/doi.org\/10.1371\/journal.pone.0061217","journal-title":"PLoS One"},{"key":"1871_CR27","unstructured":"Oksanen J, Blanchet FG, Kindt R, Legendre P, Minchin PR, O\u2019Hara RB, Simpson GL, Solymos P, Stevens MHH, Wagner H (2012) vegan: Community Ecology Package. R package version 2.0\u201310. https:\/\/CRAN.R-project.org\/package=vegan"},{"key":"1871_CR28","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1890\/13-0133.1","volume":"84","author":"A Chao","year":"2014","unstructured":"Chao A, Gotelli NJ, Hsieh TC, Sander EL, Ma KH, Colwell RK, Ellison AM (2014) Rarefaction and extrapolation with hill numbers: a framework for sampling and estimation in species diversity studies. Ecol Monogr 84:45\u201367. https:\/\/doi.org\/10.1890\/13-0133.1","journal-title":"Ecol Monogr"},{"key":"1871_CR29","unstructured":"Hsieh TC, Ma KH, Chao A (2025) iNEXT: Interpolation and extrapolation for species diversity. R package version 3.0.2. http:\/\/chao.stat.nthu.edu.tw\/wordpress\/software_download\/"},{"issue":"8","key":"1871_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0229277","volume":"15","author":"TC Dias","year":"2020","unstructured":"Dias TC, Stabach JA, Huang Q, Labruna MB, Leimgruber P et al (2020) Habitat selection in natural and human-modified landscapes by capybaras (Hydrochoerus hydrochaeris), an important host for Amblyomma sculptum ticks. PLOS ONE 15(8):e0229277. https:\/\/doi.org\/10.1371\/journal.pone.0229277","journal-title":"PLOS ONE"},{"issue":"9","key":"1871_CR31","doi-asserted-by":"publisher","first-page":"3184","DOI":"10.1128\/jcm.01270-14","volume":"52","author":"P Ramanan","year":"2014","unstructured":"Ramanan P, Barreto JN, Osmo DR, Tosh PK (2014) Rothia bacteremia: a 10-year experience at Mayo Clinic, Rochester, Minnesota. J Clin Microbiol 52(9):3184\u20133189. https:\/\/doi.org\/10.1128\/jcm.01270-14","journal-title":"J Clin Microbiol"},{"issue":"1","key":"1871_CR32","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.diagmicrobio.2016.01.005","volume":"85","author":"MZ Abidi","year":"2016","unstructured":"Abidi MZ, Ledeboer N, Banerjee A, Hari P (2016) Morbidity and mortality attributable to Rothia bacteremia in neutropenic and nonneutropenic patients. Diagn Microbiol Infect Dis 85(1):116\u2013120. https:\/\/doi.org\/10.1016\/j.diagmicrobio.2016.01.005","journal-title":"Diagn Microbiol Infect Dis"},{"key":"1871_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2021.104877","volume":"93","author":"M Fatahi-Bafghi","year":"2021","unstructured":"Fatahi-Bafghi M (2021) Characterization of the Rothia spp. and their role in human clinical infections. Infect Genet Evol 93:104877. https:\/\/doi.org\/10.1016\/j.meegid.2021.104877","journal-title":"Infect Genet Evol"},{"issue":"2","key":"1871_CR34","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1056\/nejm199901143400202","volume":"340","author":"DA Talan","year":"1999","unstructured":"Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ (1999) Bacteriologic analysis of infected dog and cat bites. N Engl J Med 340(2):85\u201392. https:\/\/doi.org\/10.1056\/nejm199901143400202","journal-title":"N Engl J Med"},{"issue":"2","key":"1871_CR35","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/S0196-0644(85)81073-8","volume":"14","author":"GJ Ordog","year":"1985","unstructured":"Ordog GJ, Balasubramanium S, Wasserberger J (1985) Rat bites: fifty cases. Ann Emerg Med 14(2):126\u2013130. https:\/\/doi.org\/10.1016\/S0196-0644(85)81073-8","journal-title":"Ann Emerg Med"},{"issue":"10","key":"1871_CR36","doi-asserted-by":"publisher","first-page":"3468","DOI":"10.1128\/jcm.00607-07","volume":"45","author":"NE Holmes","year":"2007","unstructured":"Holmes NE, Korman TM (2007) Corynebacterium kutscheri infection of skin and soft tissue following rat bite. J Clin Microbiol 45(10):3468\u20133469. https:\/\/doi.org\/10.1128\/jcm.00607-07","journal-title":"J Clin Microbiol"},{"issue":"4","key":"1871_CR37","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/s0934-8840(11)80091-5","volume":"274","author":"M Bedn\u00e1r","year":"1991","unstructured":"Bedn\u00e1r M, M\u00e1ra M (1991) Immunostimulatory effect of Rothia dentocariosa in mice. Zentralbl Bakteriol 274(4):527\u2013532. https:\/\/doi.org\/10.1016\/s0934-8840(11)80091-5","journal-title":"Zentralbl Bakteriol"},{"key":"1871_CR38","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-97057-1","volume":"11","author":"S Yip","year":"2021","unstructured":"Yip S, Dehcheshmeh MM, McLelland DJ, Boardman WSJ, Saputra S, Ebrahimie E, Weyrich LS, Bird PS, Trott DJ (2021) <Emphasis Type=\"Italic\">Porphyromonas<\/Emphasis> spp., <Emphasis Type=\"Italic\">Fusobacterium<\/Emphasis> spp., and <Emphasis Type=\"Italic\">Bacteroides<\/Emphasis> spp. dominate microbiota in the course of macropod progressive periodontal disease. Sci Rep 11:17775. https:\/\/doi.org\/10.1038\/s41598-021-97057-1","journal-title":"Sci Rep"},{"key":"1871_CR39","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/S1094-9194(03)00041-0","volume":"6","author":"LFJ Legendre","year":"2003","unstructured":"Legendre LFJ (2003) Oral disorders of exotic rodents. Vet Clin North Am Exotic Anim Pract 6:601\u2013628. https:\/\/doi.org\/10.1016\/S1094-9194(03)00041-0","journal-title":"Vet Clin North Am Exotic Anim Pract"},{"issue":"2","key":"1871_CR40","doi-asserted-by":"publisher","first-page":"185","DOI":"10.7589\/0090-3558-40.2.185","volume":"40","author":"AW Sainsbury","year":"2004","unstructured":"Sainsbury AW, Kountouri A, DuBoulay G, Kertesz P (2004) Oral disease in free-living red squirrels (Sciurus vulgaris) in the united Kingdom. J Wildl Dis 40(2):185\u2013196. https:\/\/doi.org\/10.7589\/0090-3558-40.2.185","journal-title":"J Wildl Dis"},{"issue":"4","key":"1871_CR41","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1111\/j.1600-0765.2009.01245.x","volume":"45","author":"S Liang","year":"2010","unstructured":"Liang S, Hosur KB, Domon H, Hajishengallis G (2010) Periodontal inflammation and bone loss in aged mice. J Periodontal Res 45(4):574\u2013578. https:\/\/doi.org\/10.1111\/j.1600-0765.2009.01245.x","journal-title":"J Periodontal Res"},{"issue":"6","key":"1871_CR42","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1111\/j.1399-302x.2005.00239.x","volume":"20","author":"P K\u00f5ll-Klais","year":"2005","unstructured":"K\u00f5ll-Klais P, M\u00e4ndar R, Leibur E, Marcotte H, Hammarstr\u00f6m L, Mikelsaar M (2005) Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiol Immunol 20(6):354\u2013361. https:\/\/doi.org\/10.1111\/j.1399-302x.2005.00239.x","journal-title":"Oral Microbiol Immunol"},{"issue":"1","key":"1871_CR43","doi-asserted-by":"publisher","first-page":"9","DOI":"10.4167\/jbv.2011.41.1.9","volume":"41","author":"MS Kang","year":"2011","unstructured":"Kang MS, Lim HS, Kim SM, Lee HC, Oh JS (2011) Effect of Weissella cibaria on Fusobacterium nucleatum \u2013 induced interleukin-6 and interleukin-8 production in KB cells. J Bacteriol Virol 41(1):9\u201318. https:\/\/doi.org\/10.4167\/jbv.2011.41.1.9","journal-title":"J Bacteriol Virol"},{"key":"1871_CR44","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-020-01231-2","volume":"20","author":"MS Kang","year":"2020","unstructured":"Kang MS, Lee DS, Lee SA, Kim MS, Nam SH (2020) Effects of probiotic bacterium Weissella cibaria CMU on periodontal health and microbiota: a randomised, double-blind, placebo-controlled trial. BMC Oral Health 20:243. https:\/\/doi.org\/10.1186\/s12903-020-01231-2","journal-title":"BMC Oral Health"},{"issue":"12","key":"1871_CR45","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1177\/00220345241272011","volume":"103","author":"K Yama","year":"2024","unstructured":"Yama K, Morishima S, Tsutsumi K, Jo R, Aita Y, Inokuchi T, Okuda T, Watai D, Ohara K, Maruyama M, Chikazawa T, Iwamoto T, Kakizawa Y, Oniki T (2024) Oral microbiota development in the first 60 months: a longitudinal study. J Dent Res 103(12):1249\u20131257. https:\/\/doi.org\/10.1177\/00220345241272011","journal-title":"J Dent Res"},{"issue":"2","key":"1871_CR46","doi-asserted-by":"publisher","DOI":"10.3390\/dj7020058","volume":"7","author":"L Sedghi","year":"2019","unstructured":"Sedghi L, Byron C, Jennings R, Chlipala GE, Green SJ, Silo-Suh L (2019) Effect of dietary fiber on the composition of the murine dental microbiome. Dent J 7(2):58. https:\/\/doi.org\/10.3390\/dj7020058","journal-title":"Dent J"}],"container-title":["Brazilian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-026-01871-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s42770-026-01871-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42770-026-01871-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:51:17Z","timestamp":1781632277000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s42770-026-01871-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,3]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["1871"],"URL":"https:\/\/doi.org\/10.1007\/s42770-026-01871-6","relation":{},"ISSN":["1517-8382","1678-4405"],"issn-type":[{"value":"1517-8382","type":"print"},{"value":"1678-4405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,3]]},"assertion":[{"value":"6 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was authorized by Chico Mendes Institute for Biodiversity (ICMBio Permit No. 70679-5) and was approved by the Ethical Committee of Animal Use of the Federal University of Goi\u00e1s (protocol No. 092\/19).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institutional review board statement"}},{"value":"The authors declare no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"48"}}