{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T10:57:09Z","timestamp":1778410629625,"version":"3.51.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1007\/s43032-020-00197-4","type":"journal-article","created":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T14:51:48Z","timestamp":1589899908000},"page":"1391-1399","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2"],"prefix":"10.1007","volume":"27","author":[{"given":"Fang","family":"Ren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danni","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yizi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuishan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,5,19]]},"reference":[{"issue":"25","key":"197_CR1","doi-asserted-by":"publisher","first-page":"40402","DOI":"10.18632\/oncotarget.16316","volume":"8","author":"S Oki","year":"2017","unstructured":"Oki S, Sone K, Oda K, et al. Oncogenic histone methyltransferase EZH2: a novel prognostic marker with therapeutic potential in endometrial cancer. Oncotarget. 2017;8(25):40402\u201311.","journal-title":"Oncotarget."},{"issue":"1","key":"197_CR2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/0090-8258(83)90111-7","volume":"15","author":"JV Bokhman","year":"1983","unstructured":"Bokhman JV. Two pathogenetic types of endometrial carcinoma. Gynecol Oncol. 1983;15(1):10\u20137.","journal-title":"Gynecol Oncol."},{"issue":"3","key":"197_CR3","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1097\/IGC.0000000000001184","volume":"28","author":"MC Noer","year":"2018","unstructured":"Noer MC, Antonsen SL, Ottesen B, Christensen IJ, H\u00f8gdall C. Type I versus type II endometrial cancer: differential impact of comorbidity. Int J Gynecol Cancer. 2018;28(3):586\u201393.","journal-title":"Int J Gynecol Cancer."},{"issue":"8","key":"197_CR4","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1002\/gcc.20569","volume":"47","author":"SH Nordgard","year":"2008","unstructured":"Nordgard SH, Johansen FE, Alnaes GI, et al. Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients. Genes Chromosomes Cancer. 2008;47(8):680\u201396.","journal-title":"Genes Chromosomes Cancer."},{"issue":"4","key":"197_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002079","volume":"3","author":"W Chung","year":"2008","unstructured":"Chung W, Kwabi-Addo B, Ittmann M, et al. Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One. 2008;3(4):e2079.","journal-title":"PLoS One."},{"key":"197_CR6","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/1757-2215-7-73","volume":"7","author":"F Ren","year":"2014","unstructured":"Ren F, Wang DB, Li T, Chen YH, Li Y. Identification of differentially methylated genes in the malignant transformation of ovarian endometriosis. J Ovarian Res. 2014;7:73.","journal-title":"J Ovarian Res."},{"issue":"1","key":"197_CR7","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/cas.12573","volume":"106","author":"CT Wang","year":"2015","unstructured":"Wang CT, Wang DB, Liu KR, et al. Inducing malignant transformation of endometriosis in rats by long-term sustaining hyperestrogenemia and type II diabetes. Cancer Sci. 2015;106(1):43\u201350.","journal-title":"Cancer Sci."},{"issue":"3","key":"197_CR8","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1007\/s00404-011-2046-z","volume":"285","author":"A Rodolakis","year":"2012","unstructured":"Rodolakis A, Thomakos N, Akrivos N, et al. Clinicopathologic insight of simultaneously detected primary endometrial and ovarian carcinomas. Arch Gynecol Obstet. 2012;285(3):817\u201321.","journal-title":"Arch Gynecol Obstet."},{"issue":"1","key":"197_CR9","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1111\/j.1432-1033.1993.tb17930.x","volume":"214","author":"PM Alliel","year":"1993","unstructured":"Alliel PM, Perin JP, Jolles P, Bonnet F. Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour. Eur J Biochem. 1993;214(1):347\u201350.","journal-title":"Eur J Biochem."},{"issue":"4","key":"197_CR10","doi-asserted-by":"publisher","first-page":"749","DOI":"10.3349\/ymj.2017.58.4.749","volume":"58","author":"O Sambuudash","year":"2017","unstructured":"Sambuudash O, Kim HS, Cho MY. Lack of aberrant methylation in an adjacent area of left-sided colorectal cancer. Yonsei Med J. 2017;58(4):749\u201355.","journal-title":"Yonsei Med J."},{"issue":"11","key":"197_CR11","first-page":"822","volume":"46","author":"F Ren","year":"2011","unstructured":"Ren F, Wang DB, Li T. Epigenetic inactivation of SPOCK2 in the malignant transformation of ovarian endometriosis. Zhonghua Fu Chan Ke Za Zhi. 2011;46(11):822\u20135.","journal-title":"Zhonghua Fu Chan Ke Za Zhi."},{"issue":"3","key":"197_CR12","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1159\/000369745","volume":"35","author":"H Song","year":"2015","unstructured":"Song H, Pan D, Sun W, et al. SiRNA directed against annexin II receptor inhibits angiogenesis via suppressing MMP2 and MMP9 expression. Cell Physiol Biochem. 2015;35(3):875\u201384.","journal-title":"Cell Physiol Biochem."},{"issue":"2","key":"197_CR13","doi-asserted-by":"publisher","first-page":"641","DOI":"10.3892\/ijo.2015.3034","volume":"47","author":"HY Wang","year":"2015","unstructured":"Wang HY, Tu YS, Long J, et al. SRF-miR 29b-MMP2 axis inhibits NSCLC invasion and metastasis. Int J Oncol. 2015;47(2):641\u20139.","journal-title":"Int J Oncol."},{"issue":"6","key":"197_CR14","doi-asserted-by":"publisher","first-page":"2541","DOI":"10.3892\/ijo.2014.2646","volume":"45","author":"SA Yi","year":"2014","unstructured":"Yi SA, Ryu HW, Lee DH, Han JW, Kwon SH. HP1\u03b2 suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2. Int J Oncol. 2014;45(6):2541\u20138.","journal-title":"Int J Oncol."},{"issue":"4","key":"197_CR15","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1111\/j.1349-7006.2010.01498.x","volume":"101","author":"H Sato","year":"2010","unstructured":"Sato H, Takino T. Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion. Cancer Sci. 2010;101(4):843\u20137.","journal-title":"Cancer Sci."},{"issue":"4","key":"197_CR16","first-page":"265","volume":"4","author":"D Al-Raawi","year":"2011","unstructured":"Al-Raawi D, Abu-El-Zahab H, El-Shinawi M, Mohamed MM. Membrane type-1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancer. Int J Clin Exp Med. 2011;4(4):265\u201375.","journal-title":"Int J Clin Exp Med."},{"issue":"3","key":"197_CR17","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1083\/jcb.148.3.615","volume":"148","author":"N Koshikawa","year":"2000","unstructured":"Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V. Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. J Cell Biol. 2000;148(3):615\u201324.","journal-title":"J Cell Biol."},{"issue":"10","key":"197_CR18","doi-asserted-by":"publisher","first-page":"8440","DOI":"10.1074\/jbc.M109128200","volume":"277","author":"K Lehti","year":"2002","unstructured":"Lehti K, Lohi J, Juntunen MM, Pei D, Keski-Oja J. Oligomerization through hemopexin and cytoplasmic domains regulates the activity and turnover of membrane-type 1 matrix metalloproteinase. J Biol Chem. 2002;277(10):8440\u20138.","journal-title":"J Biol Chem."},{"issue":"24","key":"197_CR19","first-page":"8896","volume":"61","author":"M Nakada","year":"2001","unstructured":"Nakada M, Yamada A, Takino T, et al. Suppression of membrane-type 1 matrix metalloproteinase (MMP)-mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product. N-Tes. Cancer Res. 2001;61(24):8896\u2013902.","journal-title":"N-Tes. Cancer Res."},{"issue":"12","key":"197_CR20","first-page":"3364","volume":"63","author":"M Nakada","year":"2003","unstructured":"Nakada M, Miyamori H, Yamashita J, Sato H. Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins. Cancer Res. 2003;63(12):3364\u20139.","journal-title":"Cancer Res."},{"key":"197_CR21","doi-asserted-by":"crossref","unstructured":"Berger EA, McClellan SA, Barrett RP, Hazlett LD. Testican-1 promotes resistance against Pseudomonas aeruginosa-induced keratitis through regulation of MMP-2 expression and activation. Invest Ophthalmol Vis Sci. 2011;52(8):5339-5346.","DOI":"10.1167\/iovs.10-6920"},{"issue":"4","key":"197_CR22","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1111\/j.1349-7006.2007.00426.x","volume":"98","author":"T Kudo","year":"2007","unstructured":"Kudo T, Takino T, Miyamori H, Thompson EW, Sato H. Substrate choice of membrane-type matrix metalloproteinase is dictated by tissue inhibitor of metalloproteinase-2 levels. Cancer Sci. 2007;98(4):563\u20138.","journal-title":"Cancer Sci."},{"issue":"6","key":"197_CR23","doi-asserted-by":"publisher","first-page":"3566","DOI":"10.3892\/or.2016.4757","volume":"35","author":"J Yang","year":"2016","unstructured":"Yang J, Yang Q, Yu J, Li X, Yu S, Zhang X. SPOCK1 promotes the proliferation, migration and invasion of glioma through PI3K\/AKT and Wnt\/\u03b2-catenin signaling pathways. Oncol Rep. 2016;35(6):3566\u201376.","journal-title":"Oncol Rep."},{"issue":"2","key":"197_CR24","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/jcmm.13357","volume":"22","author":"D Chen","year":"2018","unstructured":"Chen D, Zhou H, Liu G, Zhao Y, Cao G, Liu Q. SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug-induced epithelial\u2013mesenchymal transition. J Cell Mol Med. 2018;22(2):797\u2013807.","journal-title":"J Cell Mol Med."}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-020-00197-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-020-00197-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-020-00197-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T14:52:16Z","timestamp":1721919136000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-020-00197-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,19]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["197"],"URL":"https:\/\/doi.org\/10.1007\/s43032-020-00197-4","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,19]]},"assertion":[{"value":"19 May 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}