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The study was approved by the Institutional Review Board at Columbia University Irving Medical Center (IRBAAAI0337 approved on 12\/9\/2010; IRBAAAJ2106 approved on 7\/25\/2012; IRBAAAK3805 approved on 10\/24\/2012) and at Rowan University School of Osteopathic Medicine (IRB Pro2012002203 approved on 1\/17\/13).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Informed consent was obtained from all participants in the studies included in this manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}}]}}