{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T15:25:55Z","timestamp":1767713155934,"version":"3.37.3"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:00:00Z","timestamp":1595980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:00:00Z","timestamp":1595980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100012352","name":"Universit\u00e0 degli Studi di Milano","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012352","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Heterotopic cervical pregnancy is a rare and potentially dangerous condition where the challenge is the removal of the ectopic pregnancy while preserving the intrauterine one. We present the case of an otherwise healthy 36-year-old woman with heterotopic cervical pregnancy after an IVF cycle for tubal infertility. At 6.5\u00a0weeks after a consultation with gynecologists and interventional radiologists, the patient agreed to undergo microwave ablation of the cervical pregnancy. Monthly ultrasound examination showed the persistence of non homogeneous and vascularized tissue in the cervix. Intrauterine pregnancy continued without complications until 37\u00a0weeks when a cesarean section was performed for sudden and profuse bleeding, in the presence of uterine contractions. A healthy baby girl was delivered, and the postoperative course was otherwise uncomplicated. Heterotopic cervical pregnancies are rare, and no consolidated and risk-free treatments are available at the moment. Here, we present a case of heterotopic cervical pregnancy treated successfully and without complications with microwave ablation.<\/jats:p>","DOI":"10.1007\/s43032-020-00270-y","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T16:06:06Z","timestamp":1603123566000},"page":"27-30","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Successful Transvaginal Microwave Ablation of a Heterotopic Cervical Pregnancy. A Case Report"],"prefix":"10.1007","volume":"28","author":[{"given":"Gabriella","family":"Schivardi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore Alessio","family":"Angileri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giampiero","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia","family":"Di Meglio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Brusati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Maria","family":"Ierardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianpaolo","family":"Carrafiello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6295-1854","authenticated-orcid":false,"given":"Anna Maria","family":"Marconi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,29]]},"reference":[{"key":"270_CR1","first-page":"2145937","volume":"2016","author":"A Chadee","year":"2016","unstructured":"Chadee A, Rezai S, Kirby C, Chadwick E, Gottimukkala S, Hamaoui A, et al. Spontaneous heterotopic pregnancy: dual case report and review of literature. Case Rep Obstet Gynecol. 2016;2016:2145937.","journal-title":"Case Rep Obstet Gynecol"},{"issue":"3","key":"270_CR2","doi-asserted-by":"publisher","first-page":"706.e1","DOI":"10.1016\/j.fertnstert.2006.12.030","volume":"88","author":"S Nitke","year":"2007","unstructured":"Nitke S, Horowitz E, Farhi J, Krissi H, Shalev J. Combined intrauterine and twin cervical pregnancy managed by a new conservative modality. Fertil Steril. 2007;88(3):706.e1\u20133.","journal-title":"Fertil Steril"},{"issue":"3","key":"270_CR3","first-page":"290","volume":"23","author":"MEFF Terra","year":"2019","unstructured":"Terra MEFF, Giordano LA, Giordano MV, S\u00e1 RAM, Campos F, Yadid IM, et al. Heterotopic cervical pregnancy after in-vitro fertilization - case report and literature review. JBRA Assist Reprod. 2019;23(3):290\u20136.","journal-title":"JBRA Assist Reprod"},{"key":"270_CR4","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1067\/j.cpradiol.2007.08.011","volume":"38","author":"CL Brace","year":"2009","unstructured":"Brace CL. Microwave ablation technology: what every user should know. Curr Probl Diagn Radiol. 2009;38:61\u20137.","journal-title":"Curr Probl Diagn Radiol"},{"issue":"2","key":"270_CR5","doi-asserted-by":"publisher","first-page":"59","DOI":"10.21037\/gs.2017.11.05","volume":"7","author":"AM Ierardi","year":"2018","unstructured":"Ierardi AM, Biondetti P, Coppola A, Fumarola EM, Biasina AM, Angileri AS, et al. Percutaneous microwave thermosphere ablation of pancreatic tumours. 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Ultrasound Obstet Gynecol. 2013;41:470\u20131.","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"4","key":"270_CR8","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/pd.5423","volume":"39","author":"X Meng","year":"2019","unstructured":"Meng X, Yuan P, Gong L, Wang X, Wu T, Wei Y, et al. Forty-five consecutive cases of complicated monochorionic multiple pregnancy treated with microwave ablation: a single-center experience. Prenat Diagn. 2019;39(4):293\u20138.","journal-title":"Prenat Diagn"},{"issue":"1","key":"270_CR9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1159\/000369384","volume":"38","author":"CD Stephenson","year":"2015","unstructured":"Stephenson CD, Temming LA, Pollack R, Iannitti DA. Microwave ablation for twin-reversed arterial perfusion sequence: a novel application of technology. Fetal Diagn Ther. 2015;38(1):35\u201340.","journal-title":"Fetal Diagn Ther"},{"key":"270_CR10","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1111\/jog.14131","volume":"46","author":"H Quian","year":"2020","unstructured":"Quian H, Tian G, Zheng H, Liang W, Jiang T. Successful management of diaphragmatic ectopic pregnancy using ultrasound-guided percutaneous microwave ablation. J Obstet Gynaecol Res. 2020;46:181\u20135.","journal-title":"J Obstet Gynaecol Res"}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-020-00270-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-020-00270-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-020-00270-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T23:45:00Z","timestamp":1627515900000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-020-00270-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,29]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["270"],"URL":"https:\/\/doi.org\/10.1007\/s43032-020-00270-y","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"type":"print","value":"1933-7191"},{"type":"electronic","value":"1933-7205"}],"subject":[],"published":{"date-parts":[[2020,7,29]]},"assertion":[{"value":"10 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interests"}},{"value":"This is an observational study. The XYZ Research Ethics Committee has confirmed that no ethical approval is required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}