{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T20:18:11Z","timestamp":1788293891484,"version":"build-2803163510"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100005412","name":"Shahid Chamran University of Ahvaz","doi-asserted-by":"crossref","award":["97\/3\/02\/26247"],"award-info":[{"award-number":["97\/3\/02\/26247"]}],"id":[{"id":"10.13039\/501100005412","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s43032-021-00733-w","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T18:09:59Z","timestamp":1631038199000},"page":"84-90","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Sperm miR-34c-5p Transcript Content and Its Association with Sperm Parameters in Unexplained Infertile Men"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1182-9685","authenticated-orcid":false,"given":"Mehran","family":"Dorostghoal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Galehdari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Hemadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elahe","family":"Davoodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,7]]},"reference":[{"key":"733_CR1","doi-asserted-by":"publisher","unstructured":"Esteves S, Schattman G, Agarwal A. Definitions and relevance of unexplained infertility in reproductive medicine. In: Schattman G, Esteves S, Agarwal A, editors. Unexplained infertility. New York: Springer; 2015. pp:3\u20135. https:\/\/doi.org\/10.1007\/978-1-4939-2140-9_1","DOI":"10.1007\/978-1-4939-2140-9_1"},{"issue":"9","key":"733_CR2","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1093\/humrep\/dex234","volume":"32","author":"F Zegers-Hochschild","year":"2017","unstructured":"Zegers-Hochschild F, Adamson GD, Dyer S, Racowsky C, de Mouzon J, Sokol R, et al. The international glossary on infertility and fertility care. Hum Reprod. 2017;32(9):1786\u2013801. https:\/\/doi.org\/10.1093\/humrep\/dex234.","journal-title":"Hum Reprod"},{"issue":"5","key":"733_CR3","doi-asserted-by":"publisher","first-page":"669","DOI":"10.4103\/1008-682X.125412","volume":"16","author":"R Klaver","year":"2014","unstructured":"Klaver R, Gromoll J. Bringing epigenetics into the diagnostics of the andrology laboratory: challenges and perspectives. Asian J Androl. 2014;16(5):669\u201374. https:\/\/doi.org\/10.4103\/1008-682X.125412.","journal-title":"Asian J Androl"},{"issue":"2","key":"733_CR4","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1080\/19396368.2016.1274791","volume":"63","author":"GJ Timothy","year":"2017","unstructured":"Timothy GJ, Kenneth IA, Emma RJ, Douglas TC. Sperm epigenetics in the study of male fertility, offspring health, and potential clinical applications. Syst Biol Reprod Med. 2017;63(2):69\u201376. https:\/\/doi.org\/10.1080\/19396368.2016.1274791.","journal-title":"Syst Biol Reprod Med"},{"issue":"5","key":"733_CR5","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1093\/humupd\/dmy017","volume":"24","author":"J Castillo","year":"2018","unstructured":"Castillo J, Jodar M, Oliva R. The contribution of human sperm proteins to the development and epigenome of the preimplantation embryo. Hum Reprod Update. 2018;24(5):535\u201355. https:\/\/doi.org\/10.1093\/humupd\/dmy017.","journal-title":"Hum Reprod Update"},{"issue":"1","key":"733_CR6","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1093\/biolre\/ioy007","volume":"99","author":"M G\u00f2dia","year":"2018","unstructured":"G\u00f2dia M, Swanson G, Krawetz SA. A history of why fathers\u2019 RNA matters. Biol Reprod. 2018;99(1):147\u201359. https:\/\/doi.org\/10.1093\/biolre\/ioy007.","journal-title":"Biol Reprod"},{"issue":"8","key":"733_CR7","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1038\/nrm3838","volume":"15","author":"M Ha","year":"2014","unstructured":"Ha M, Kim VN. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol. 2014;15(8):509\u201324. https:\/\/doi.org\/10.1038\/nrm3838.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"733_CR8","doi-asserted-by":"publisher","first-page":"402","DOI":"10.3389\/fendo.2018.00402","volume":"9","author":"J O'Brien","year":"2018","unstructured":"O\u2019Brien J, Hayder H, Zayed Y, Peng C. Overview of microRNA biogenesis, mechanisms of actions, and circulation. Front Endocrinol (Lausanne). 2018;9:402. https:\/\/doi.org\/10.3389\/fendo.2018.00402.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"733_CR9","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1016\/j.fertnstert.2012.11.054","volume":"99","author":"M Abu-Halima","year":"2013","unstructured":"Abu-Halima M, Hammadeh M, Schmitt J, Leidinger P, Keller A, Meese E, et al. Altered microRNA expression profiles of human spermatozoa in patients with different spermatogenic impairments. Fertil Steril. 2013;99(5):1249-1255.e16. https:\/\/doi.org\/10.1016\/j.fertnstert.2012.11.054.","journal-title":"Fertil Steril"},{"issue":"1","key":"733_CR10","doi-asserted-by":"publisher","first-page":"10358","DOI":"10.1038\/s41598-019-46775-8","volume":"9","author":"MBR Alves","year":"2019","unstructured":"Alves MBR, De Arruda RP, De Bem THC, Florez-Rodriguez SA, De S\u00e1 Filho MF, Belleann\u00e9e C, et al. Sperm-borne miR-216b modulates cell proliferation during early embryo development via K-RAS. Sci Rep. 2019;9(1):10358. https:\/\/doi.org\/10.1038\/s41598-019-46775-8.","journal-title":"Sci Rep"},{"key":"733_CR11","doi-asserted-by":"publisher","first-page":"765","DOI":"10.3389\/fphys.2019.00765","volume":"10","author":"H Gao","year":"2019","unstructured":"Gao H, Wen H, Cao C, Dong D, Yang C, Xie S, et al. Overexpression of microRNA-10a in germ cells causes male infertility by targeting Rad51 in mouse and human. Front Physiol. 2019;10:765. https:\/\/doi.org\/10.3389\/fphys.2019.00765.","journal-title":"Front Physiol"},{"key":"733_CR12","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.fertnstert.2014.07.001","volume":"102","author":"M Abu-Halima","year":"2014","unstructured":"Abu-Halima M, Hammadeh M, Backes C, Fischer U, Leidinger P, Lubbad AM, et al. Panel of five microRNAs as potential biomarkers for the diagnosis and assessment of male infertility. Fertil Steril. 2014;102:989-997.e1. https:\/\/doi.org\/10.1016\/j.fertnstert.2014.07.001.","journal-title":"Fertil Steril"},{"key":"733_CR13","doi-asserted-by":"publisher","first-page":"4302754","DOI":"10.1155\/2016\/4302754","volume":"2016","author":"T Mostafa","year":"2016","unstructured":"Mostafa T, Rashed LA, Nabil NI, Osman I, Mostafa R, Farag M. Seminal miRNA relationship with apoptotic markers and oxidative stress in infertile men with varicocele. Biomed Res Int. 2016;2016:4302754. https:\/\/doi.org\/10.1155\/2016\/4302754.","journal-title":"Biomed Res Int"},{"issue":"1","key":"733_CR14","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s43032-019-00025-4","volume":"27","author":"A Momeni","year":"2020","unstructured":"Momeni A, Najafipour R, Hamta A, Jahani S, Moghbelinejad S. Expression and methylation pattern of hsa-miR-34 family in sperm samples of infertile men. Reprod Sci. 2020;27(1):301\u20138. https:\/\/doi.org\/10.1007\/s43032-019-00025-4.","journal-title":"Reprod Sci"},{"issue":"2","key":"733_CR15","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/cpr.12013","volume":"46","author":"M Li","year":"2013","unstructured":"Li M, Yu M, Liu C, Zhu H, He X, Peng S, et al. miR-34c works downstream of p53 leading to dairy goat male germline stem-cell (mGSCs) apoptosis. Cell Prolif. 2013;46(2):223\u201331. https:\/\/doi.org\/10.1111\/cpr.12013.","journal-title":"Cell Prolif"},{"issue":"2","key":"733_CR16","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1002\/jcb.24655","volume":"115","author":"M Yu","year":"2014","unstructured":"Yu M, Mu H, Niu Z, Chu Z, Zhu H, Hua J. miR-34c enhances mouse spermatogonial stem cells differentiation by targeting Nanos2. J Cell Biochem. 2014;115(2):232\u201342. https:\/\/doi.org\/10.1002\/jcb.24655.","journal-title":"J Cell Biochem"},{"issue":"3","key":"733_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033861","volume":"7","author":"X Liang","year":"2012","unstructured":"Liang X, Zhou D, Wei C, Luo H, Liu J, Fu R, et al. MicroRNA-34c enhances murine male germ cell apoptosis through targeting ATF1. PLoS ONE. 2012;7(3): e33861. https:\/\/doi.org\/10.1371\/journal.pone.0033861.","journal-title":"PLoS ONE"},{"issue":"12","key":"733_CR18","doi-asserted-by":"publisher","first-page":"1722","DOI":"10.1373\/clinchem.2011.169714","volume":"57","author":"C Wang","year":"2011","unstructured":"Wang C, Yang C, Chen X, Yao B, Yang C, Zhu C, et al. Altered profile of seminal plasma microRNAs in the molecular diagnosis of male infertility. Clin Chem. 2011;57(12):1722\u201331. https:\/\/doi.org\/10.1373\/clinchem.2011.169714.","journal-title":"Clin Chem"},{"issue":"5","key":"733_CR19","doi-asserted-by":"publisher","first-page":"17991","DOI":"10.1038\/srep17991","volume":"9","author":"X Munoz","year":"2015","unstructured":"Munoz X, Mata A, Bassas L, Larriba S. Altered miRNA signature of developing germ-cells in infertile patients relates to the severity of spermatogenic failure and persists in spermatozoa. Sci Rep. 2015 Dec;9(5):17991. https:\/\/doi.org\/10.1038\/srep17991.","journal-title":"Sci Rep"},{"key":"733_CR20","doi-asserted-by":"publisher","unstructured":"Rahbar S, Novin MG, Alizadeh E, Shahnazi V, Pashaei-Asl F, AsrBadr YA,et al. New insights into the expression profile of microRNA-34c and P53 in infertile men spermatozoa and testicular tissue. Cell Mol Biol (Noisy-le-grand). 2017;63(8):77\u201383. https:\/\/doi.org\/10.14715\/cmb\/2017.63.8.17.","DOI":"10.14715\/cmb\/2017.63.8.17"},{"key":"733_CR21","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1073\/pnas.1110368109","volume":"109","author":"WM Liu","year":"2012","unstructured":"Liu WM, Pang RT, Chiu PC, Wong BP, Lao K, Lee KF, et al. Sperm-borne microRNA-34c is required for the first cleavage division in mouse. Proc Natl Acad Sci USA. 2012;109:490\u20134. https:\/\/doi.org\/10.1073\/pnas.1110368109.","journal-title":"Proc Natl Acad Sci USA"},{"key":"733_CR22","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1186\/1477-7827-12-85","volume":"12","author":"A Tscherner","year":"2014","unstructured":"Tscherner A, Gilchrist G, Smith N, Blondin P, Gillis D, LaMarre J. MicroRNA-34 family expression in bovine gametes and preimplantation embryos. Reprod Biol Endocrinol. 2014;12:85. https:\/\/doi.org\/10.1186\/1477-7827-12-85.","journal-title":"Reprod Biol Endocrinol"},{"key":"733_CR23","doi-asserted-by":"publisher","first-page":"4470","DOI":"10.1093\/nar\/gkt139","volume":"41","author":"K Soni","year":"2013","unstructured":"Soni K, Choudhary A, Patowary A, Singh AR, Bhatia S, Sivasubbu S, et al. MiR-34 is maternally inherited in Drosophila melanogaster and Danio rerio. Nucl Acids Res. 2013;41:4470\u201380. https:\/\/doi.org\/10.1093\/nar\/gkt139.","journal-title":"Nucl Acids Res"},{"issue":"2","key":"733_CR24","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.fertnstert.2015.05.003","volume":"104","author":"L Cui","year":"2015","unstructured":"Cui L, Fang L, Shi B, Qiu S, Ye Y. Spermatozoa micro ribonucleic acid-34c level is correlated with intracytoplasmic sperm injection outcomes. Fertil Steril. 2015;104(2):312-7.e1. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.05.003.","journal-title":"Fertil Steril"},{"key":"733_CR25","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1242\/bio.201410959","volume":"4","author":"S Yuan","year":"2015","unstructured":"Yuan S, Tang C, Zhang Y, Wu J, Bao J, Zheng H, et al. Mir-34b\/c and mir-449a\/b\/c are required for spermatogenesis, but not for the first cleavage division in mice. Biology Open. 2015;4:212\u201323. https:\/\/doi.org\/10.1242\/bio.201410959.","journal-title":"Biology Open"},{"key":"733_CR26","volume-title":"WHO Laboratory manual for the examination and processing of human semen","author":"World Health Organisation","year":"2010","unstructured":"World Health Organisation. WHO Laboratory manual for the examination and processing of human semen. 5th ed. Geneva: World Health Organization; 2010.","edition":"5"},{"issue":"3","key":"733_CR27","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1080\/01485010701216526","volume":"53","author":"R Goodrich","year":"2007","unstructured":"Goodrich R, Johnson G, Krawetz SA. The preparation of human spermatozoa RNA for clinical analysis. Arch Androl. 2007;53(3):161\u20137. https:\/\/doi.org\/10.1080\/01485010701216526.","journal-title":"Arch Androl"},{"key":"733_CR28","doi-asserted-by":"publisher","unstructured":"Fiedler SD, Carletti MZ. Christenson LK. Quantitative RT-PCR methods for mature microRNA expression analysis.\u00a0Methods Mol Biol.\u00a02010; 630:49\u201364.\u00a0https:\/\/doi.org\/10.1007\/978-1-60761-629-0_4.","DOI":"10.1007\/978-1-60761-629-0_4"},{"key":"733_CR29","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.ydbio.2007.09.009","volume":"311","author":"S Ro","year":"2007","unstructured":"Ro S, Park C, Sanders KM, McCarrey JR, Yan W. Cloning and expression profiling of testis-expressed microRNAs. Dev Biol. 2007;311:592\u2013602. https:\/\/doi.org\/10.1016\/j.ydbio.2007.09.009.","journal-title":"Dev Biol"},{"issue":"30","key":"733_CR30","doi-asserted-by":"publisher","first-page":"25173","DOI":"10.1074\/jbc.M112.362053","volume":"287","author":"Q Wu","year":"2012","unstructured":"Wu Q, Song R, Ortogero N, Zheng H, Evanoff R, Small CL, et al. The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis. J Biol Chem. 2012;287(30):25173\u201390. https:\/\/doi.org\/10.1074\/jbc.M112.362053.","journal-title":"J Biol Chem"},{"issue":"6988","key":"733_CR31","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1038\/429154a","volume":"429","author":"GC Ostermeier","year":"2004","unstructured":"Ostermeier GC, Miller D, Huntriss JD, Diamond MP, Krawetz SA. Reproductive biology: delivering spermatozoan RNA to the oocyte. Nature. 2004;429(6988):154. https:\/\/doi.org\/10.1038\/429154a.","journal-title":"Nature"},{"issue":"10","key":"733_CR32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pegn.1004597","volume":"10","author":"S Comazzetto","year":"2014","unstructured":"Comazzetto S, Di Giacomo M, Rasmussen KD, Much C, Azzi C, Perlas E, et al. Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b\/c and miR-449 loci. PLoS Genet. 2014;10(10): e1004597. https:\/\/doi.org\/10.1371\/journal.pegn.1004597.","journal-title":"PLoS Genet"},{"issue":"6","key":"733_CR33","doi-asserted-by":"publisher","first-page":"4373","DOI":"10.1007\/s11033-020-05552-x","volume":"47","author":"F Finocchi","year":"2020","unstructured":"Finocchi F, Pelloni M, Balercia G, Pallotti F, Radicioni AF, Lenzi A, et al. Seminal plasma miRNAs in Klinefelter syndrome and in obstructive and non-obstructive azoospermia. Mol Biol Rep. 2020;47(6):4373\u201382. https:\/\/doi.org\/10.1007\/s11033-020-05552-x.","journal-title":"Mol Biol Rep"},{"key":"733_CR34","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12610-015-0018-z","volume":"25","author":"AA Dabaja","year":"2015","unstructured":"Dabaja AA, Mielnik A, Robinson BD, Wosnitzer MS, Schlegel PN, Paduch DA. Possible germ cell-Sertoli cell interactions are critical for establishing appropriate expression levels for the Sertoli cell-specific microRNA, miR-202-5p, in human testis. Basic Clin Androl. 2015;25:2. https:\/\/doi.org\/10.1186\/s12610-015-0018-z.","journal-title":"Basic Clin Androl"},{"issue":"6","key":"733_CR35","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1095\/biolreprod.106.056499","volume":"75","author":"M Amanai","year":"2006","unstructured":"Amanai M, Brahmajosyula M, Perry ACF. A restricted role for sperm-borne microRNAs in mammalian fertilization. Biol Reprod. 2006;75(6):877\u201384. https:\/\/doi.org\/10.1095\/biolreprod.106.056499.","journal-title":"Biol Reprod"},{"issue":"1","key":"733_CR36","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1186\/s12864-020-6570-8","volume":"21","author":"H Xu","year":"2020","unstructured":"Xu H, Wang X, Wang Z, Li J, Xu Z, Miao M, et al. MicroRNA expression profile analysis in sperm reveals hsa-mir-191 as an auspicious omen of in vitro fertilization. BMC Genomics. 2020;21(1):165. https:\/\/doi.org\/10.1186\/s12864-020-6570-8.","journal-title":"BMC Genomics"},{"issue":"28","key":"733_CR37","doi-asserted-by":"publisher","first-page":"E2851","DOI":"10.1073\/pnas.1407777111","volume":"111","author":"J Wu","year":"2014","unstructured":"Wu J, Bao J, Kim M, Yuan S, Tang C, Zheng H, Mastick GS, Xu C, Yan W. Two miRNA clusters, miR-34b\/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci USA. 2014;111(28):E2851\u20137. https:\/\/doi.org\/10.1073\/pnas.1407777111.","journal-title":"Proc Natl Acad Sci USA"},{"key":"733_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.117895","volume":"256","author":"S Shi","year":"2020","unstructured":"Shi S, Shi Q, Sun Y. The effect of sperm miR-34c on human embryonic development kinetics and clinical outcomes. Life Sci. 2020;256: 117895. https:\/\/doi.org\/10.1016\/j.lfs.2020.117895.","journal-title":"Life Sci"},{"issue":"1","key":"733_CR39","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1038\/s41398-018-0146-2","volume":"8","author":"DA Dickson","year":"2018","unstructured":"Dickson DA, Paulus JK, Mensah V, Lem J, Saavedra-Rodriguez L, Gentry A. Reduced levels of miRNAs 449 and 34 in sperm of mice and men exposed to early life stress. Transl Psychiatry. 2018;8(1):101. https:\/\/doi.org\/10.1038\/s41398-018-0146-2.","journal-title":"Transl Psychiatry"},{"issue":"4","key":"733_CR40","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1261\/rna.1963810","volume":"16","author":"F Bouhallier","year":"2010","unstructured":"Bouhallier F, Allioli N, Lavial F, Chalmel F, Perrard MH, Durand P, et al. Role of miR-34c microRNA in the late steps of spermatogenesis. RNA. 2010;16(4):720\u201331. https:\/\/doi.org\/10.1261\/rna.1963810.","journal-title":"RNA"},{"issue":"4","key":"733_CR41","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s10815-009-9305-y","volume":"26","author":"N Yan","year":"2009","unstructured":"Yan N, Lu Y, Sun H, Qiu W, Tao D, Liu Y, et al. Microarray profiling of microRNAs expressed in testis tissues of developing primates. J Assist Reprod Genet. 2009;26(4):179\u201386. https:\/\/doi.org\/10.1007\/s10815-009-9305-y.","journal-title":"J Assist Reprod Genet"},{"issue":"3","key":"733_CR42","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1080\/15476286.2018.1445959","volume":"15","author":"JF Lima","year":"2018","unstructured":"Lima JF, Cerqueira L, Figueiredo C, Oliveira C, Azevedo NF. Anti-miRNA oligonucleotides: a comprehensive guide for design. RNA Biol. 2018;15(3):338\u201352. https:\/\/doi.org\/10.1080\/15476286.2018.1445959.","journal-title":"RNA Biol"}],"updated-by":[{"DOI":"10.1007\/s43032-021-00770-5","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T00:00:00Z","timestamp":1635465600000}}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-021-00733-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-021-00733-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-021-00733-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T18:31:18Z","timestamp":1639679478000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-021-00733-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,7]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["733"],"URL":"https:\/\/doi.org\/10.1007\/s43032-021-00733-w","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s43032-021-00770-5","asserted-by":"object"}]},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,7]]},"assertion":[{"value":"26 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2021","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article was updated to correct a spelling error in the title.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2021","order":7,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":8,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":9,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s43032-021-00770-5","URL":"https:\/\/doi.org\/10.1007\/s43032-021-00770-5","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Ethics Committee of the Department of Biology, Shahid Chamran University of Ahvaz, approved the present study (No.20.6.505, EE\/97.24.3.70398\/scu.ac.ir).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"The written informed consent was obtained from all the subjects enrolled in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}