{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T23:30:05Z","timestamp":1792279805480,"version":"4.4.0"},"reference-count":198,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["grant number 17-BS05"],"award-info":[{"award-number":["grant number 17-BS05"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology , Ministry of Science and Technology","doi-asserted-by":"publisher","award":["BT\/PR6946\/MED"],"award-info":[{"award-number":["BT\/PR6946\/MED"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s43032-022-00989-w","type":"journal-article","created":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T15:02:25Z","timestamp":1654700545000},"page":"408-427","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Maternal PUFAs, Placental Epigenetics, and Their Relevance to Fetal Growth and Brain Development"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8161-5597","authenticated-orcid":false,"given":"Sanjay","family":"Basak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim K.","family":"Duttaroy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,8]]},"reference":[{"issue":"1","key":"989_CR1","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1093\/jn\/132.1.88","volume":"132","author":"KS Broughton","year":"2002","unstructured":"Broughton KS, Wade JW. Total fat and (n-3):(n-6) fat ratios influence eicosanoid production in mice. J Nutr. 2002;132(1):88\u201394.","journal-title":"J Nutr"},{"issue":"2","key":"989_CR2","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1530\/REP-14-0549","volume":"149","author":"JA Keelan","year":"2015","unstructured":"Keelan JA, Mas E, D\u2019Vaz N, Dunstan JA, Li S, Barden AE, et al. Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors. Reproduction. 2015;149(2):171\u20138.","journal-title":"Reproduction"},{"issue":"4","key":"989_CR3","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1093\/ajcn\/87.4.887","volume":"87","author":"M van Eijsden","year":"2008","unstructured":"van Eijsden M, Hornstra G, van der Wal MF, Vrijkotte TG, Bonsel GJ. Maternal n-3, n-6, and trans fatty acid profile early in pregnancy and term birth weight: a prospective cohort study. Am J Clin Nutr. 2008;87(4):887\u201395.","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"989_CR4","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1017\/S0007114508006740","volume":"101","author":"CE Dirix","year":"2009","unstructured":"Dirix CE, Kester AD, Hornstra G. Associations between neonatal birth dimensions and maternal essential and trans fatty acid contents during pregnancy and at delivery. Br J Nutr. 2009;101(3):399\u2013407.","journal-title":"Br J Nutr"},{"issue":"1","key":"989_CR5","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12937-018-0353-y","volume":"17","author":"E Lee","year":"2018","unstructured":"Lee E, Kim H, Kim H, Ha E-H, Chang N. Association of maternal omega-6 fatty acid intake with infant birth outcomes: Korean Mothers and Children\u2019s Environmental Health (MOCEH). Nutr J. 2018;17(1):47\u201356.","journal-title":"Nutr J"},{"issue":"2","key":"989_CR6","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1093\/ije\/dyw010","volume":"45","author":"I Mani","year":"2016","unstructured":"Mani I, Dwarkanath P, Thomas T, Thomas A, Kurpad AV. Maternal fat and fatty acid intake and birth outcomes in a South Indian population. Int J Epidemiol. 2016;45(2):523\u201331.","journal-title":"Int J Epidemiol"},{"issue":"2","key":"989_CR7","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1093\/ajcn\/69.2.293","volume":"69","author":"FV Velzing-Aarts","year":"1999","unstructured":"Velzing-Aarts FV, van der Klis FR, van der Dijs FP, Muskiet FA. Umbilical vessels of preeclamptic women have low contents of both n-3 and n-6 long-chain polyunsaturated fatty acids. Am J Clin Nutr. 1999;69(2):293\u20138.","journal-title":"Am J Clin Nutr"},{"issue":"33","key":"989_CR8","first-page":"1","volume":"7","author":"AN Sferruzzi-Perri","year":"2016","unstructured":"Sferruzzi-Perri AN, Camm EJ. The programming power of the placenta. Front Physiol. 2016;7(33):1\u201328.","journal-title":"Front Physiol"},{"issue":"1","key":"989_CR9","doi-asserted-by":"publisher","first-page":"24","DOI":"10.2174\/1389201015666140330192345","volume":"15","author":"E Herrera","year":"2014","unstructured":"Herrera E, Ortega-Senovilla H. Lipid metabolism during pregnancy and its implications for fetal growth. Curr Pharm Biotechnol. 2014;15(1):24\u201331.","journal-title":"Curr Pharm Biotechnol"},{"issue":"2s","key":"989_CR10","doi-asserted-by":"publisher","first-page":"S745","DOI":"10.1016\/j.ajog.2017.11.577","volume":"218","author":"GJ Burton","year":"2018","unstructured":"Burton GJ, Jauniaux E. Pathophysiology of placental-derived fetal growth restriction. Am J Obstet Gynecol. 2018;218(2s):S745\u201361.","journal-title":"Am J Obstet Gynecol"},{"issue":"5728","key":"989_CR11","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1126\/science.1111726","volume":"308","author":"CW Redman","year":"2005","unstructured":"Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science. 2005;308(5728):1592\u20134.","journal-title":"Science"},{"issue":"5","key":"989_CR12","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1042\/CS20050292","volume":"110","author":"DO Bates","year":"2006","unstructured":"Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, et al. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term. Clin Sci. 2006;110(5):575\u201385.","journal-title":"Clin Sci"},{"key":"989_CR13","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1152\/physiol.00043.2008","volume":"24","author":"A Wang","year":"2009","unstructured":"Wang A, Rana S, Karumanchi SA. Preeclampsia: the role of angiogenic factors in its pathogenesis. Physiology. 2009;24:147\u201358.","journal-title":"Physiology"},{"key":"989_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2011\/123717","volume":"2011","author":"M Furuya","year":"2011","unstructured":"Furuya M, Kurasawa K, Nagahama K, Kawachi K, Nozawa A, Takahashi T, et al. Disrupted balance of angiogenic and antiangiogenic signalings in preeclampsia. J Pregnancy. 2011;2011:1\u201310.","journal-title":"J Pregnancy"},{"issue":"10","key":"989_CR15","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.3109\/14767058.2011.589932","volume":"24","author":"T Chaiworapongsa","year":"2011","unstructured":"Chaiworapongsa T, Romero R, Savasan ZA, Kusanovic JP, Ogge G, Soto E, et al. Maternal plasma concentrations of angiogenic\/anti-angiogenic factors are of prognostic value in patients presenting to the obstetrical triage area with the suspicion of preeclampsia. J Matern Fetal Neo. 2011;24(10):1187\u2013207.","journal-title":"J Matern Fetal Neo"},{"issue":"6","key":"989_CR16","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.1093\/advances\/nmab070","volume":"12","author":"Z Huang","year":"2021","unstructured":"Huang Z, Huang S, Song T, Yin Y, Tan C. Placental angiogenesis in mammals: a review of the regulatory effects of signaling pathways and functional nutrients. Adv Nutr. 2021;12(6):2415\u201334.","journal-title":"Adv Nutr"},{"issue":"6","key":"989_CR17","doi-asserted-by":"publisher","first-page":"6841","DOI":"10.1016\/j.ajog.2017.10.003","volume":"217","author":"AL Conroy","year":"2017","unstructured":"Conroy AL, McDonald CR, Gamble JL, Olwoch P, Natureeba P, Cohan D, et al. Altered angiogenesis as a common mechanism underlying preterm birth, small for gestational age, and stillbirth in women living with HIV. Am J Obstet Gynecol. 2017;217(6):6841-684.17.","journal-title":"Am J Obstet Gynecol."},{"issue":"8","key":"989_CR18","doi-asserted-by":"publisher","first-page":"e0182509","DOI":"10.1371\/journal.pone.0182509","volume":"12","author":"F Troncoso","year":"2017","unstructured":"Troncoso F, Acurio J, Herlitz K, Aguayo C, Bertoglia P, Guzman-Gutierrez E, et al. Gestational diabetes mellitus is associated with increased pro-migratory activation of vascular endothelial growth factor receptor 2 and reduced expression of vascular endothelial growth factor receptor 1. PloS one. 2017;12(8):e0182509.","journal-title":"PloS one."},{"issue":"2\u20133","key":"989_CR19","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1053\/plac.2001.0757","volume":"23","author":"TR Regnault","year":"2002","unstructured":"Regnault TR, Orbus RJ, de Vrijer B, Davidsen ML, Galan HL, Wilkening RB, et al. Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR). Placenta. 2002;23(2\u20133):132\u201344.","journal-title":"Placenta"},{"key":"989_CR20","doi-asserted-by":"publisher","first-page":"102109","DOI":"10.1016\/j.plefa.2020.102109","volume":"158","author":"S Basak","year":"2020","unstructured":"Basak S, Vilasagaram S, Duttaroy AK. Maternal dietary deficiency of n-3 fatty acids affects metabolic and epigenetic phenotypes of the developing fetus. Prostaglandins Leukot Essent Fatty Acids. 2020;158:102109\u201320.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"2","key":"989_CR21","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.bbalip.2018.11.003","volume":"1864","author":"J Peng","year":"2019","unstructured":"Peng J, Zhou Y, Hong Z, Wu Y, Cai A, Xia M, et al. Maternal eicosapentaenoic acid feeding promotes placental angiogenesis through a Sirtuin-1 independent inflammatory pathway. Biochim Biophys Acta. 2019;1864(2):147\u201357.","journal-title":"Biochim Biophys Acta"},{"issue":"9","key":"989_CR22","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/j.placenta.2011.06.009","volume":"32","author":"GM Johnsen","year":"2011","unstructured":"Johnsen GM, Basak S, Weedon-Fekj\u00e6r MS, Staff AC, Duttaroy AK. Docosahexaenoic acid stimulates tube formation in first trimester trophoblast cells, HTR8\/SVneo. Placenta. 2011;32(9):626\u201332.","journal-title":"Placenta"},{"issue":"21","key":"989_CR23","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.lfs.2013.09.024","volume":"93","author":"S Basak","year":"2013","unstructured":"Basak S, Das MK, Duttaroy AK. Fatty acid-induced angiogenesis in first trimester placental trophoblast cells: possible roles of cellular fatty acid-binding proteins. Life Sci. 2013;93(21):755\u201362.","journal-title":"Life Sci"},{"issue":"2","key":"989_CR24","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.plefa.2012.10.001","volume":"88","author":"S Basak","year":"2013","unstructured":"Basak S, Duttaroy AK. Effects of fatty acids on angiogenic activity in the placental extravillious trophoblast cells. Prostaglandins Leukot Essent Fatty Acids. 2013;88(2):155\u201362.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"989_CR25","doi-asserted-by":"publisher","first-page":"102080","DOI":"10.1016\/j.plefa.2020.102080","volume":"155","author":"AK Duttaroy","year":"2020","unstructured":"Duttaroy AK, Basak S. Maternal dietary fatty acids and their roles in human placental development. Prostaglandins Leukot Essent Fatty Acids. 2020;155:102080\u20138.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"989_CR26","doi-asserted-by":"publisher","first-page":"108784","DOI":"10.1016\/j.jnutbio.2021.108784","volume":"96","author":"V Srinivas","year":"2021","unstructured":"Srinivas V, Molangiri A, Mallepogu A, Kona SR, Ibrahim A, Duttaroy AK, et al. Maternal n-3 PUFA deficiency alters uterine artery remodeling and placental epigenome in the mice. J Nutr Biochem. 2021;96:108784\u201396.","journal-title":"J Nutr Biochem"},{"issue":"8","key":"989_CR27","doi-asserted-by":"publisher","first-page":"5953","DOI":"10.1021\/acsomega.1c00196","volume":"6","author":"FP Samson","year":"2021","unstructured":"Samson FP, Fabunmi TE, Patrick AT, Jee D, Gutsaeva DR, Jahng WJ. Fatty acid composition and stoichiometry determine the angiogenesis microenvironment. ACS Omega. 2021;6(8):5953\u201361.","journal-title":"ACS Omega"},{"issue":"5","key":"989_CR28","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.3390\/nu11051107","volume":"11","author":"PP Devarshi","year":"2019","unstructured":"Devarshi PP, Grant RW, Ikonte CJ, Hazels MS. Maternal omega-3 nutrition, placental transfer and fetal brain development in gestational diabetes and preeclampsia. Nutrients. 2019;11(5):1107\u201319.","journal-title":"Nutrients"},{"issue":"Suppl 2","key":"989_CR29","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/j.1740-8709.2011.00318.x","volume":"7","author":"SM Innis","year":"2011","unstructured":"Innis SM. Metabolic programming of long-term outcomes due to fatty acid nutrition in early life. Matern Child Nutr. 2011;7(Suppl 2):112\u201323.","journal-title":"Matern Child Nutr"},{"issue":"9","key":"989_CR30","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1007\/s11745-001-0798-1","volume":"36","author":"R Uauy","year":"2001","unstructured":"Uauy R, Hoffman DR, Peirano P, Birch DG, Birch EE. Essential fatty acids in visual and brain development. Lipids. 2001;36(9):885\u201395.","journal-title":"Lipids"},{"issue":"4","key":"989_CR31","first-page":"163","volume":"3","author":"JM Coletta","year":"2010","unstructured":"Coletta JM, Bell SJ, Roman AS. Omega-3 fatty acids and pregnancy. Rev Obstet Gynecol. 2010;3(4):163\u201371.","journal-title":"Rev Obstet Gynecol"},{"issue":"3","key":"989_CR32","first-page":"389","volume":"18","author":"P Dwarkanath","year":"2009","unstructured":"Dwarkanath P, Muthayya S, Thomas T, Vaz M, Parikh P, Mehra R, et al. Polyunsaturated fatty acid consumption and concentration among South Indian women during pregnancy. Asia Pac J Clin Nutr. 2009;18(3):389\u201394.","journal-title":"Asia Pac J Clin Nutr"},{"key":"989_CR33","doi-asserted-by":"crossref","unstructured":"Koletzko B. Trans fatty acids may impair biosynthesis of long-chain polyunsaturates and growth in man. Acta paediatrica (Oslo, Norway : 1992). 1992;81(4):302\u20136.","DOI":"10.1111\/j.1651-2227.1992.tb12230.x"},{"issue":"4","key":"989_CR34","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/j.bbalip.2013.01.012","volume":"1831","author":"S Basak","year":"2013","unstructured":"Basak S, Duttaroy AK. cis-9, trans-11 conjugated linoleic acid stimulates expression of angiopoietin like-4 in the placental extravillous trophoblast cells. Biochim Biophys Acta. 2013;1831(4):834\u201343.","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"989_CR35","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.atherosclerosissup.2006.04.006","volume":"7","author":"G Hornstra","year":"2006","unstructured":"Hornstra G, van Eijsden M, Dirix C, Bonsel G. Trans fatty acids and birth outcome: some first results of the MEFAB and ABCD cohorts. Atheroscler Suppl. 2006;7(2):21\u20133.","journal-title":"Atheroscler Suppl"},{"issue":"8","key":"989_CR36","doi-asserted-by":"publisher","first-page":"2526","DOI":"10.1093\/jn\/133.8.2526","volume":"133","author":"E Larqu\u00e9","year":"2003","unstructured":"Larqu\u00e9 E, Garc\u00eda-Ruiz PA, Perez-Llamas F, Zamora S, Gil A. Dietary trans fatty acids alter the compositions of microsomes and mitochondria and the activities of microsome delta6-fatty acid desaturase and glucose-6-phosphatase in livers of pregnant rats. J Nutr. 2003;133(8):2526\u201331.","journal-title":"J Nutr"},{"issue":"4","key":"989_CR37","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1016\/j.clnu.2017.06.010","volume":"37","author":"NH Grootendorst-van Mil","year":"2018","unstructured":"Grootendorst-van Mil NH, Tiemeier H, Steenweg-de Graaff J, Koletzko B, Demmelmair H, Jaddoe VWV, et al. Maternal plasma n-3 and n-6 polyunsaturated fatty acids during pregnancy and features of fetal health: Fetal growth velocity, birth weight and duration of pregnancy. Clin Nutr (Edinburgh, Scotland). 2018;37(4):1367\u201374.","journal-title":"Clin Nutr (Edinburgh, Scotland)"},{"key":"989_CR38","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/1471-2393-13-23","volume":"13","author":"LJ Smits","year":"2013","unstructured":"Smits LJ, Elzenga HM, Gemke RJ, Hornstra G, van Eijsden M. The association between interpregnancy interval and birth weight: what is the role of maternal polyunsaturated fatty acid status? BMC Pregnancy Childbirth. 2013;13:23\u201332.","journal-title":"BMC Pregnancy Childbirth"},{"issue":"1","key":"989_CR39","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/s41430-019-0428-7","volume":"74","author":"P Kamenju","year":"2020","unstructured":"Kamenju P, Hertzmark E, Kabagambe EK, Smith ER, Muhihi A, Noor RA, et al. Factors associated with plasma n-3 and n-6 polyunsaturated fatty acid levels in Tanzanian infants. Eur J Clin Nutr. 2020;74(1):97\u2013105.","journal-title":"Eur J Clin Nutr"},{"issue":"6","key":"989_CR40","doi-asserted-by":"publisher","first-page":"1467S","DOI":"10.1093\/ajcn\/83.6.1467S","volume":"83","author":"LM Arterburn","year":"2006","unstructured":"Arterburn LM, Hall EB, Oken H. Distribution, interconversion, and dose response of n\u22123 fatty acids in humans. Am J Clin Nutr. 2006;83(6):1467S-S1476.","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"989_CR41","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1053\/euhj.2001.2728","volume":"23","author":"CP Leeson","year":"2002","unstructured":"Leeson CP, Mann A, Kattenhorn M, Deanfield JE, Lucas A, Muller DP. Relationship between circulating n-3 fatty acid concentrations and endothelial function in early adulthood. Eur Heart J. 2002;23(3):216\u201322.","journal-title":"Eur Heart J"},{"issue":"4","key":"989_CR42","first-page":"537","volume":"68","author":"UM M\u00e4kil\u00e4","year":"1986","unstructured":"M\u00e4kil\u00e4 UM, Jouppila P, Kirkinen P, Viinikka L, Ylikorkala O. Placental thromboxane and prostacyclin in the regulation of placental blood flow. Obstet Gynecol. 1986;68(4):537\u201340.","journal-title":"Obstet Gynecol"},{"issue":"1","key":"989_CR43","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1093\/ajcn\/70.1.53","volume":"70","author":"V Wijendran","year":"1999","unstructured":"Wijendran V, Bendel RB, Couch SC, Philipson EH, Thomsen K, Zhang X, et al. Maternal plasma phospholipid polyunsaturated fatty acids in pregnancy with and without gestational diabetes mellitus: relations with maternal factors. Am J Clin Nutr. 1999;70(1):53\u201361.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"989_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1095\/biolreprod.111.098095","volume":"87","author":"E Dube","year":"2012","unstructured":"Dube E, Gravel A, Martin C, Desparois G, Moussa I, Ethier-Chiasson M, et al. Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta. Biol Reprod. 2012;87(1):1\u201311.","journal-title":"Biol Reprod"},{"issue":"3","key":"989_CR45","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.placenta.2014.01.003","volume":"35","author":"J Saben","year":"2014","unstructured":"Saben J, Lindsey F, Zhong Y, Thakali K, Badger TM, Andres A, et al. Maternal obesity is associated with a lipotoxic placental environment. Placenta. 2014;35(3):171\u20137.","journal-title":"Placenta"},{"issue":"8","key":"989_CR46","doi-asserted-by":"publisher","first-page":"2352","DOI":"10.1194\/jlr.M006866","volume":"51","author":"F Massiera","year":"2010","unstructured":"Massiera F, Barbry P, Guesnet P, Joly A, Luquet S, Moreilhon-Brest C, et al. A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations. J Lipid Res. 2010;51(8):2352\u201361.","journal-title":"J Lipid Res"},{"issue":"9","key":"989_CR47","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/j.molmet.2014.09.003","volume":"3","author":"DF Pisani","year":"2014","unstructured":"Pisani DF, Ghandour RA, Beranger GE, Le Faouder P, Chambard J-C, Giroud M, et al. The \u03c96-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin\/calcium mediated pathway. Mol Metab. 2014;3(9):834\u201347.","journal-title":"Mol Metab"},{"key":"989_CR48","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.mce.2015.04.025","volume":"412","author":"L Cheng","year":"2015","unstructured":"Cheng L, Yu Y, Zhang Q, Szabo A, Wang H, Huang XF. Arachidonic acid impairs hypothalamic leptin signaling and hepatic energy homeostasis in mice. Mol Cell Endocrinol. 2015;412:12\u20138.","journal-title":"Mol Cell Endocrinol"},{"issue":"5","key":"989_CR49","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.clnu.2011.03.002","volume":"30","author":"C Tian","year":"2011","unstructured":"Tian C, Fan C, Liu X, Xu F, Qi K. Brain histological changes in young mice submitted to diets with different ratios of n-6\/n-3 polyunsaturated fatty acids during maternal pregnancy and lactation. Clin Nutr (Edinburgh, Scotland). 2011;30(5):659\u201367.","journal-title":"Clin Nutr (Edinburgh, Scotland)"},{"issue":"2","key":"989_CR50","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/sj.mp.4001887","volume":"12","author":"JS Rao","year":"2007","unstructured":"Rao JS, Ertley RN, DeMar JC Jr, Rapoport SI, Bazinet RP, Lee HJ. Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex. Mol Psychiatry. 2007;12(2):151\u20137.","journal-title":"Mol Psychiatry"},{"issue":"5","key":"989_CR51","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1111\/j.1471-4159.2004.02789.x","volume":"91","author":"JC DeMar Jr","year":"2004","unstructured":"DeMar JC Jr, Ma K, Bell JM, Rapoport SI. Half-lives of docosahexaenoic acid in rat brain phospholipids are prolonged by 15 weeks of nutritional deprivation of n-3 polyunsaturated fatty acids. J Neurochem. 2004;91(5):1125\u201337.","journal-title":"J Neurochem"},{"issue":"4","key":"989_CR52","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/S0002-9378(97)70620-3","volume":"176","author":"MS Reece","year":"1997","unstructured":"Reece MS, McGregor JA, Allen KG, Harris MA. Maternal and perinatal long-chain fatty acids: possible roles in preterm birth. Am J Obstet Gynecol. 1997;176(4):907\u201314.","journal-title":"Am J Obstet Gynecol"},{"issue":"30","key":"989_CR53","doi-asserted-by":"publisher","first-page":"10931","DOI":"10.1073\/pnas.0402342101","volume":"101","author":"K Kitajka","year":"2004","unstructured":"Kitajka K, Sinclair AJ, Weisinger RS, Weisinger HS, Mathai M, Jayasooriya AP, et al. Effects of dietary omega-3 polyunsaturated fatty acids on brain gene expression. Proc Natl Acad Sci U S A. 2004;101(30):10931\u20136.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"989_CR54","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/s11745-010-3523-z","volume":"46","author":"A Harauma","year":"2011","unstructured":"Harauma A, Moriguchi T. Dietary n-3 fatty acid deficiency in mice enhances anxiety induced by chronic mild stress. Lipids. 2011;46(5):409\u201316.","journal-title":"Lipids"},{"issue":"12","key":"989_CR55","doi-asserted-by":"publisher","first-page":"e28451","DOI":"10.1371\/journal.pone.0028451","volume":"6","author":"HS Bhatia","year":"2011","unstructured":"Bhatia HS, Agrawal R, Sharma S, Huo YX, Ying Z, Gomez-Pinilla F. Omega-3 fatty acid deficiency during brain maturation reduces neuronal and behavioral plasticity in adulthood. PLoS ONE. 2011;6(12):e28451\u201360.","journal-title":"PLoS ONE"},{"issue":"1","key":"989_CR56","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s12974-017-0869-7","volume":"14","author":"NRV Dragano","year":"2017","unstructured":"Dragano NRV, Solon C, Ramalho AF, de Moura RF, Razolli DS, Christiansen E, et al. Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation. J Neuroinflammation. 2017;14(1):91\u2013107.","journal-title":"J Neuroinflammation"},{"issue":"6","key":"989_CR57","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1093\/jn\/136.6.1570","volume":"136","author":"P Coti Bertrand","year":"2006","unstructured":"Coti Bertrand P, O\u2019Kusky JR, Innis SM. Maternal dietary (n-3) fatty acid deficiency alters neurogenesis in the embryonic rat brain. J Nutr. 2006;136(6):1570\u20135.","journal-title":"J Nutr"},{"issue":"3","key":"989_CR58","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/S0022-2275(20)34485-0","volume":"41","author":"I Carrie","year":"2000","unstructured":"Carrie I, Clement M, de Javel D, Frances H, Bourre JM. Specific phospholipid fatty acid composition of brain regions in mice. Effects of n-3 polyunsaturated fatty acid deficiency and phospholipid supplementation. J Lipid Res. 2000;41(3):465\u201372.","journal-title":"J Lipid Res."},{"issue":"1","key":"989_CR59","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.biopsych.2013.06.007","volume":"75","author":"CO Bondi","year":"2014","unstructured":"Bondi CO, Taha AY, Tock JL, Totah NK, Cheon Y, Torres GE, et al. Adolescent behavior and dopamine availability are uniquely sensitive to dietary omega-3 fatty acid deficiency. Biol Psychiat. 2014;75(1):38\u201346.","journal-title":"Biol Psychiat"},{"key":"989_CR60","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ijdevneu.2017.09.003","volume":"64","author":"S Auguste","year":"2018","unstructured":"Auguste S, Sharma S, Fisette A, Fernandes MF, Daneault C, Des Rosiers C, et al. Perinatal deficiency in dietary omega-3 fatty acids potentiates sucrose reward and diet-induced obesity in mice. Int J Dev Neurosci\u202f: Off J Int Soc Dev Neurosci. 2018;64:8\u201313.","journal-title":"Int J Dev Neurosci : Off J Int Soc Dev Neurosci"},{"issue":"4","key":"989_CR61","doi-asserted-by":"publisher","first-page":"e62031","DOI":"10.1371\/journal.pone.0062031","volume":"8","author":"JR Bernardi","year":"2013","unstructured":"Bernardi JR, Ferreira CF, Senter G, Krolow R, de Aguiar BW, Portella AK, et al. Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats. PLoS ONE. 2013;8(4):e62031\u201342.","journal-title":"PLoS ONE"},{"issue":"4","key":"989_CR62","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.cmet.2020.02.012","volume":"31","author":"F Ducrocq","year":"2020","unstructured":"Ducrocq F, Walle R, Contini A, Oummadi A, Caraballo B, van der Veldt S, et al. Causal link between n-3 polyunsaturated fatty acid deficiency and motivation deficits. Cell Metab. 2020;31(4):755-72.e7.","journal-title":"Cell Metab"},{"issue":"1","key":"989_CR63","doi-asserted-by":"publisher","first-page":"6133","DOI":"10.1038\/s41467-020-19861-z","volume":"11","author":"C Madore","year":"2020","unstructured":"Madore C, Leyrolle Q, Morel L, Rossitto M, Greenhalgh AD, Delpech JC, et al. Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. Nat Commun. 2020;11(1):6133\u201352.","journal-title":"Nat Commun"},{"issue":"11","key":"989_CR64","doi-asserted-by":"publisher","first-page":"2662","DOI":"10.1016\/j.bbamem.2016.07.005","volume":"1858","author":"MV Borroni","year":"2016","unstructured":"Borroni MV, Vall\u00e9s AS, Barrantes FJ. The lipid habitats of neurotransmitter receptors in brain. Biochim et Biophys Acta (BBA) - Biomembranes. 2016;1858(11):2662\u201370.","journal-title":"Biochim et Biophys Acta (BBA) - Biomembranes"},{"issue":"2","key":"989_CR65","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1111\/j.1471-4159.2009.06335.x","volume":"111","author":"D Cao","year":"2009","unstructured":"Cao D, Kevala K, Kim J, Moon HS, Jun SB, Lovinger D, et al. Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function. J Neurochem. 2009;111(2):510\u201321.","journal-title":"J Neurochem"},{"issue":"5","key":"989_CR66","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1007\/s11064-008-9845-z","volume":"34","author":"L Dagai","year":"2009","unstructured":"Dagai L, Peri-Naor R, Birk RZ. Docosahexaenoic acid significantly stimulates immediate early response genes and neurite outgrowth. Neurochem Res. 2009;34(5):867\u201375.","journal-title":"Neurochem Res"},{"issue":"3","key":"989_CR67","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.neuroscience.2009.02.057","volume":"160","author":"M Katakura","year":"2009","unstructured":"Katakura M, Hashimoto M, Shahdat HM, Gamoh S, Okui T, Matsuzaki K, et al. Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix\u2013loop\u2013helix transcription factors and cell cycle in neural stem cells. Neuroscience. 2009;160(3):651\u201360.","journal-title":"Neuroscience"},{"issue":"4","key":"989_CR68","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1111\/j.1471-4159.2004.02520.x","volume":"90","author":"F Calderon","year":"2004","unstructured":"Calderon F, Kim HY. Docosahexaenoic acid promotes neurite growth in hippocampal neurons. J Neurochem. 2004;90(4):979\u201388.","journal-title":"J Neurochem"},{"key":"989_CR69","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.mam.2018.03.004","volume":"64","author":"HY Kim","year":"2018","unstructured":"Kim HY, Spector AA. N-Docosahexaenoylethanolamine: a neurotrophic and neuroprotective metabolite of docosahexaenoic acid. Mol Aspects Med. 2018;64:34\u201344.","journal-title":"Mol Aspects Med"},{"issue":"2","key":"989_CR70","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/s12035-011-8200-6","volume":"44","author":"NG Bazan","year":"2011","unstructured":"Bazan NG, Musto AE, Knott EJ. Endogenous signaling by omega-3 docosahexaenoic acid-derived mediators sustains homeostatic synaptic and circuitry integrity. Mol Neurobiol. 2011;44(2):216\u201322.","journal-title":"Mol Neurobiol"},{"issue":"6","key":"989_CR71","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.3390\/nu13062061","volume":"13","author":"S Basak","year":"2021","unstructured":"Basak S, Mallick R, Banerjee A, Pathak S, Duttaroy AK. Maternal supply of both arachidonic and docosahexaenoic acids is required for optimal neurodevelopment. Nutrients. 2021;13(6):2061\u201389.","journal-title":"Nutrients"},{"issue":"2","key":"989_CR72","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.bbalip.2014.10.009","volume":"1851","author":"M Hashimoto","year":"2015","unstructured":"Hashimoto M, Katakura M, Tanabe Y, Al Mamun A, Inoue T, Hossain S, et al. n-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats. Biochim Biophys Acta. 2015;1851(2):203\u20139.","journal-title":"Biochim Biophys Acta"},{"issue":"30","key":"989_CR73","doi-asserted-by":"publisher","first-page":"12390","DOI":"10.1074\/jbc.R117.783076","volume":"292","author":"A Asatryan","year":"2017","unstructured":"Asatryan A, Bazan NG. Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection. J Biol Chem. 2017;292(30):12390\u20137.","journal-title":"J Biol Chem"},{"issue":"9","key":"989_CR74","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1038\/nsmb.1474","volume":"15","author":"T Itoh","year":"2008","unstructured":"Itoh T, Fairall L, Amin K, Inaba Y, Szanto A, Balint BL, et al. Structural basis for the activation of PPARgamma by oxidized fatty acids. Nat Struct Mol Biol. 2008;15(9):924\u201331.","journal-title":"Nat Struct Mol Biol"},{"key":"989_CR75","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1146\/annurev.biochem.77.061307.091829","volume":"77","author":"P Tontonoz","year":"2008","unstructured":"Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem. 2008;77:289\u2013312.","journal-title":"Annu Rev Biochem"},{"issue":"3","key":"989_CR76","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/j.neuroscience.2006.01.021","volume":"139","author":"E Kawakita","year":"2006","unstructured":"Kawakita E, Hashimoto M, Shido O. Docosahexaenoic acid promotes neurogenesis in vitro and in vivo. Neuroscience. 2006;139(3):991\u20137.","journal-title":"Neuroscience"},{"issue":"6056","key":"989_CR77","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1038\/319774a0","volume":"319","author":"RG Morris","year":"1986","unstructured":"Morris RG, Anderson E, Lynch GS, Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature. 1986;319(6056):774\u20136.","journal-title":"Nature"},{"issue":"6510","key":"989_CR78","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/373151a0","volume":"373","author":"K Sakimura","year":"1995","unstructured":"Sakimura K, Kutsuwada T, Ito I, Manabe T, Takayama C, Kushiya E, et al. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature. 1995;373(6510):151\u20135.","journal-title":"Nature"},{"issue":"1","key":"989_CR79","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1113\/jphysiol.1994.sp020051","volume":"475","author":"M Nishikawa","year":"1994","unstructured":"Nishikawa M, Kimura S, Akaike N. Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex. J Physiol. 1994;475(1):83\u201393.","journal-title":"J Physiol"},{"issue":"7","key":"989_CR80","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1038\/sj.bjp.0703970","volume":"132","author":"S Fujita","year":"2001","unstructured":"Fujita S, Ikegaya Y, Nishikawa M, Nishiyama N, Matsuki N. Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices. Br J Pharmacol. 2001;132(7):1417\u201322.","journal-title":"Br J Pharmacol"},{"issue":"3","key":"989_CR81","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.neurobiolaging.2006.01.002","volume":"28","author":"SC Dyall","year":"2007","unstructured":"Dyall SC, Michael GJ, Whelpton R, Scott AG, Michael-Titus AT. Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B glutamate receptor subunits in rat forebrain. Neurobiol Aging. 2007;28(3):424\u201339.","journal-title":"Neurobiol Aging"},{"issue":"10","key":"989_CR82","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1089\/ars.2010.3474","volume":"14","author":"C Rink","year":"2011","unstructured":"Rink C, Khanna S. Significance of brain tissue oxygenation and the arachidonic acid cascade in stroke. Antioxid Redox Signal. 2011;14(10):1889\u2013903.","journal-title":"Antioxid Redox Signal"},{"issue":"5","key":"989_CR83","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1080\/07388551.2016.1207153","volume":"37","author":"M Hashimoto","year":"2017","unstructured":"Hashimoto M, Hossain S, Al Mamun A, Matsuzaki K, Arai H. Docosahexaenoic acid: one molecule diverse functions. Crit Rev Biotechnol. 2017;37(5):579\u201397.","journal-title":"Crit Rev Biotechnol"},{"key":"989_CR84","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.brainres.2014.11.059","volume":"1597","author":"JJ Liu","year":"2015","unstructured":"Liu JJ, Green P, John Mann J, Rapoport SI, Sublette ME. Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease. Brain Res. 2015;1597:220\u201346.","journal-title":"Brain Res"},{"issue":"4","key":"989_CR85","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1111\/jnc.12833","volume":"131","author":"V Casa\u00f1as-S\u00e1nchez","year":"2014","unstructured":"Casa\u00f1as-S\u00e1nchez V, P\u00e9rez JA, Fabelo N, Herrera-Herrera AV, Fern\u00e1ndez C, Mar\u00edn R, et al. Addition of docosahexaenoic acid, but not arachidonic acid, activates glutathione and thioredoxin antioxidant systems in murine hippocampal HT22 cells: potential implications in neuroprotection. J Neurochem. 2014;131(4):470\u201383.","journal-title":"J Neurochem"},{"key":"989_CR86","doi-asserted-by":"publisher","first-page":"203","DOI":"10.3389\/fphys.2015.00203","volume":"6","author":"V Casa\u00f1as-S\u00e1nchez","year":"2015","unstructured":"Casa\u00f1as-S\u00e1nchez V, P\u00e9rez JA, Fabelo N, Quinto-Alemany D, D\u00edaz ML. Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells. Front Physiol. 2015;6:203\u201314.","journal-title":"Front Physiol"},{"key":"989_CR87","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.plefa.2017.03.006","volume":"136","author":"GY Sun","year":"2018","unstructured":"Sun GY, Simonyi A, Fritsche KL, Chuang DY, Hannink M, Gu Z, et al. Docosahexaenoic acid (DHA): an essential nutrient and a nutraceutical for brain health and diseases. Prostaglandins Leukot Essent Fatty Acids. 2018;136:3\u201313.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"7","key":"989_CR88","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1091\/mbc.E20-09-0599","volume":"32","author":"J Drolet","year":"2021","unstructured":"Drolet J, Buchner-Duby B, Stykel MG, Coackley C, Kang JX, Ma DWL, et al. Docosahexanoic acid signals through the Nrf2-Nqo1 pathway to maintain redox balance and promote neurite outgrowth. Mol Biol Cell. 2021;32(7):511\u201320.","journal-title":"Mol Biol Cell"},{"key":"989_CR89","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.plefa.2017.11.001","volume":"128","author":"M Tang","year":"2018","unstructured":"Tang M, Zhang M, Wang L, Li H, Cai H, Dang R, et al. Maternal dietary of n-3 polyunsaturated fatty acids affects the neurogenesis and neurochemical in female rat at weaning. Prostaglandins Leukot Essent Fatty Acids. 2018;128:11\u201320.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"1","key":"989_CR90","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jnutbio.2014.08.002","volume":"26","author":"CI Janssen","year":"2015","unstructured":"Janssen CI, Zerbi V, Mutsaers MP, de Jong BS, Wiesmann M, Arnoldussen IA, et al. Impact of dietary n-3 polyunsaturated fatty acids on cognition, motor skills and hippocampal neurogenesis in developing C57BL\/6J mice. J Nutr Biochem. 2015;26(1):24\u201335.","journal-title":"J Nutr Biochem"},{"issue":"6","key":"989_CR91","doi-asserted-by":"publisher","first-page":"907","DOI":"10.3390\/antiox10060907","volume":"10","author":"M D\u00edaz","year":"2021","unstructured":"D\u00edaz M, Mesa-Herrera F, Mar\u00edn R. DHA and its elaborated modulation of antioxidant defenses of the brain: implications in aging and AD neurodegeneration. Antioxidants (Basel). 2021;10(6):907\u201333.","journal-title":"Antioxidants (Basel)"},{"issue":"2","key":"989_CR92","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/j.bbrc.2011.12.057","volume":"417","author":"F Charalambous","year":"2012","unstructured":"Charalambous F, Elia A, Georgiades P. Decidual spiral artery remodeling during early post-implantation period in mice: investigation of associations with decidual uNK cells and invasive trophoblast. Biochem Biophys Res Commun. 2012;417(2):847\u201352.","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"989_CR93","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1095\/biolreprod.116.140681","volume":"95","author":"MY Rennie","year":"2016","unstructured":"Rennie MY, Whiteley KJ, Adamson SL, Sled JG. Quantification of gestational changes in the uteroplacental vascular tree reveals vessel specific hemodynamic roles during pregnancy in mice. Biol Reprod. 2016;95(2):43\u201352.","journal-title":"Biol Reprod"},{"issue":"7347","key":"989_CR94","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1038\/nature10144","volume":"473","author":"P Carmeliet","year":"2011","unstructured":"Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature. 2011;473(7347):298\u2013307.","journal-title":"Nature"},{"issue":"1","key":"989_CR95","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/micc.12093","volume":"21","author":"D-B Chen","year":"2014","unstructured":"Chen D-B, Zheng J. Regulation of placental angiogenesis. Microcirculation. 2014;21(1):15\u201325.","journal-title":"Microcirculation"},{"issue":"9","key":"989_CR96","doi-asserted-by":"publisher","first-page":"4213","DOI":"10.1210\/jc.2002-020195","volume":"87","author":"E Geva","year":"2002","unstructured":"Geva E, Ginzinger DG, Zaloudek CJ, Moore DH, Byrne A, Jaffe RB. Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2. J Clin Endocrinol Metab. 2002;87(9):4213\u201324.","journal-title":"J Clin Endocrinol Metab"},{"key":"989_CR97","doi-asserted-by":"crossref","unstructured":"Duttaroy AK, Basak S. Placentation as a predictor of feto-placental outcome: effects of early nutrition. Early nutrition and lifestyle factors: effects on first trimester placenta. Cham: Springer International Publishing; 2016. pp.1\u201312.","DOI":"10.1007\/978-3-319-38804-5_1"},{"issue":"3","key":"989_CR98","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1210\/en.2006-0683","volume":"148","author":"VD Winn","year":"2007","unstructured":"Winn VD, Haimov-Kochman R, Paquet AC, Yang YJ, Madhusudhan MS, Gormley M, et al. Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term. Endocrinology. 2007;148(3):1059\u201379.","journal-title":"Endocrinology"},{"issue":"11","key":"989_CR99","doi-asserted-by":"publisher","first-page":"2837","DOI":"10.3390\/ijms20112837","volume":"20","author":"C Apicella","year":"2019","unstructured":"Apicella C, Ruano CSM, M\u00e9hats C, Miralles F, Vaiman D. The role of epigenetics in placental development and the etiology of preeclampsia. Int J Mol Sci. 2019;20(11):2837\u201382.","journal-title":"Int J Mol Sci"},{"issue":"7181","key":"989_CR100","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1038\/nature06613","volume":"451","author":"Z Arany","year":"2008","unstructured":"Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, et al. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature. 2008;451(7181):1008\u201312.","journal-title":"Nature"},{"issue":"9","key":"989_CR101","doi-asserted-by":"publisher","first-page":"E811","DOI":"10.1152\/ajpendo.00526.2014","volume":"309","author":"VM Pulgar","year":"2015","unstructured":"Pulgar VM, Yamaleyeva LM, Varagic J, McGee C, Bader M, Dechend R, et al. Functional changes in the uterine artery precede the hypertensive phenotype in a transgenic model of hypertensive pregnancy. Am J Physiol Endocrinol Metab. 2015;309(9):E811\u20137.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"989_CR102","doi-asserted-by":"publisher","first-page":"108925","DOI":"10.1016\/j.jnutbio.2021.108925","volume":"101","author":"S Mohammed","year":"2021","unstructured":"Mohammed S, Qadri SSY, Mir IA, Kondapalli NB, Basak S, Rajkumar H. Fructooligosaccharide ameliorates high-fat induced intrauterine inflammation and improves lipid profile in the hamster offspring. J Nutr Biochem. 2021;101:108925\u201335.","journal-title":"J Nutr Biochem"},{"issue":"5","key":"989_CR103","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1002\/oby.21821","volume":"25","author":"L Song","year":"2017","unstructured":"Song L, Sun B, Boersma GJ, Cordner ZA, Yan J, Moran TH, et al. Prenatal high-fat diet alters placental morphology, nutrient transporter expression, and mtorc1 signaling in rat. Obesity (Silver Spring). 2017;25(5):909\u201319.","journal-title":"Obesity (Silver Spring)"},{"issue":"6","key":"989_CR104","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1093\/biolre\/ioy010","volume":"98","author":"TJ Stuart","year":"2018","unstructured":"Stuart TJ, O\u2019Neill K, Condon D, Sasson I, Sen P, Xia Y, et al. Diet-induced obesity alters the maternal metabolome and early placenta transcriptome and decreases placenta vascularity in the mouse. Biol Reprod. 2018;98(6):795\u2013809.","journal-title":"Biol Reprod"},{"issue":"7","key":"989_CR105","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1080\/00016340802177412","volume":"87","author":"G Yurdakan","year":"2008","unstructured":"Yurdakan G, Ekem TE, Bahadir B, Gun BD, Kuzey GM, Ozdamar SO. Expression of adhesion molecules in first trimester spontaneous abortions and their role in abortion pathogenesis. Acta Obstet Gynecol Scand. 2008;87(7):775\u201382.","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"989_CR106","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1002\/bdrb.20000","volume":"71","author":"F Crofts","year":"2004","unstructured":"Crofts F, Rohatagi S, Pino M, DeLise B, Zhang J, Nguyen M, et al. Critical period for a teratogenic VLA-4 antagonist: developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists. Birth Defects Res B. 2004;71(2):69\u201379.","journal-title":"Birth Defects Res B"},{"issue":"3","key":"989_CR107","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1055\/s-2007-1016235","volume":"17","author":"MJ Murray","year":"1999","unstructured":"Murray MJ, Lessey BA. Embryo implantation and tumor metastasis: common pathways of invasion and angiogenesis. Semin Reprod Endocrinol. 1999;17(3):275\u201390.","journal-title":"Semin Reprod Endocrinol"},{"issue":"4","key":"989_CR108","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1530\/REP-09-0341","volume":"139","author":"M Jovanovi\u0107","year":"2010","unstructured":"Jovanovi\u0107 M, Stefanoska I, Radoj\u010di\u0107 L, Vi\u0107ovac L. Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins \u03b15 and \u03b21. Reproduction. 2010;139(4):789\u201398.","journal-title":"Reproduction"},{"issue":"6","key":"989_CR109","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1095\/biolreprod.107.063743","volume":"78","author":"CJ Lockwood","year":"2008","unstructured":"Lockwood CJ, Oner C, Uz YH, Kayisli UA, Huang SJ, Buchwalder LF, et al. Matrix metalloproteinase 9 (MMP9) expression in preeclamptic decidua and MMP9 induction by tumor necrosis factor alpha and interleukin 1 beta in human first trimester decidual cells. Biol Reprod. 2008;78(6):1064\u201372.","journal-title":"Biol Reprod"},{"issue":"2","key":"989_CR110","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.ydbio.2012.01.028","volume":"364","author":"E Monsonego-Ornan","year":"2012","unstructured":"Monsonego-Ornan E, Kosonovsky J, Bar A, Roth L, Fraggi-Rankis V, Simsa S, et al. Matrix metalloproteinase 9\/gelatinase B is required for neural crest cell migration. Dev Biol. 2012;364(2):162\u201377.","journal-title":"Dev Biol"},{"issue":"1","key":"989_CR111","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1262\/jrd.10-008K","volume":"57","author":"J Luo","year":"2011","unstructured":"Luo J, Qiao F, Yin X. Hypoxia induces FGF2 production by vascular endothelial cells and alters MMP9 and TIMP1 expression in extravillous trophoblasts and their invasiveness in a cocultured model. J Reprod Dev. 2011;57(1):84\u201391.","journal-title":"J Reprod Dev"},{"issue":"5","key":"989_CR112","first-page":"213","volume":"8","author":"N Athayde","year":"1999","unstructured":"Athayde N, Romero R, Gomez R, Maymon E, Pacora P, Mazor M, et al. Matrix metalloproteinases-9 in preterm and term human parturition. J Matern Fetal Med. 1999;8(5):213\u20139.","journal-title":"J Matern Fetal Med"},{"issue":"12","key":"989_CR113","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1093\/molehr\/7.12.1187","volume":"7","author":"U Ulug","year":"2001","unstructured":"Ulug U, Goldman S, Ben-Shlomo I, Shalev E. Matrix metalloproteinase (MMP)-2 and MMP-9 and their inhibitor, TIMP-1, in human term decidua and fetal membranes: the effect of prostaglandin F(2alpha) and indomethacin. Mol Hum Reprod. 2001;7(12):1187\u201393.","journal-title":"Mol Hum Reprod"},{"issue":"7","key":"989_CR114","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1016\/j.jnutbio.2005.10.003","volume":"17","author":"MA Perez","year":"2006","unstructured":"Perez MA, Hansen RA, Harris MA, Allen KG. Dietary docosahexaenoic acid alters pregnant rat reproductive tissue prostaglandin and matrix metalloproteinase production. J Nutr Biochem. 2006;17(7):446\u201353.","journal-title":"J Nutr Biochem"},{"issue":"6 Pt 1","key":"989_CR115","first-page":"851","volume":"95","author":"K Uchide","year":"2000","unstructured":"Uchide K, Ueno H, Inoue M, Sakai A, Fujimoto N, Okada Y. Matrix metalloproteinase-9 and tensile strength of fetal membranes in uncomplicated labor. Obstet Gynecol. 2000;95(6 Pt 1):851\u20135.","journal-title":"Obstet Gynecol"},{"issue":"5","key":"989_CR116","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1016\/S0002-9378(98)70141-3","volume":"179","author":"N Athayde","year":"1998","unstructured":"Athayde N, Edwin SS, Romero R, Gomez R, Maymon E, Pacora P, et al. A role for matrix metalloproteinase-9 in spontaneous rupture of the fetal membranes. Am J Obstet Gynecol. 1998;179(5):1248\u201353.","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"989_CR117","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1756-9966-29-4","volume":"29","author":"DE Machado","year":"2010","unstructured":"Machado DE, Berardo PT, Palmero CY, Nasciutti LE. Higher expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) and metalloproteinase-9 (MMP-9) in a rat model of peritoneal endometriosis is similar to cancer diseases. J Exp Clin Cancer Res\u202f: CR. 2010;29(1):4\u201313.","journal-title":"J Exp Clin Cancer Res : CR"},{"key":"989_CR118","doi-asserted-by":"publisher","first-page":"102094","DOI":"10.1016\/j.plefa.2020.102094","volume":"158","author":"J Whelan","year":"2020","unstructured":"Whelan J, Whelan J. Conversion of dietary polyunsaturated fats between humans and rodents: a review of allometric scaling models. Prostaglandins Leukot Essent Fatty Acids. 2020;158:102094\u2013104.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"1","key":"989_CR119","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12986-018-0330-7","volume":"16","author":"SAV Draycott","year":"2019","unstructured":"Draycott SAV, Liu G, Daniel ZC, Elmes MJ, Muhlhausler BS, Langley-Evans SC. Maternal dietary ratio of linoleic acid to alpha-linolenic acid during pregnancy has sex-specific effects on placental and fetal weights in the rat. Nutr Metab. 2019;16(1):1\u201312.","journal-title":"Nutr Metab"},{"issue":"3","key":"989_CR120","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.plefa.2012.02.004","volume":"86","author":"EM Novak","year":"2012","unstructured":"Novak EM, King DJ, Innis SM. Low linoleic acid may facilitate Delta6 desaturase activity and docosahexaenoic acid accretion in human fetal development. Prostaglandins Leukot Essent Fatty Acids. 2012;86(3):93\u20138.","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"989_CR121","doi-asserted-by":"publisher","first-page":"100622","DOI":"10.1016\/j.bbrep.2019.100622","volume":"18","author":"KM Brown","year":"2019","unstructured":"Brown KM, Sharma S, Baker E, Hawkins W, van der Merwe M, Puppa MJ. Delta-6-desaturase (FADS2) inhibition and omega-3 fatty acids in skeletal muscle protein turnover. Biochemistry and Biophysics Reports. 2019;18:100622\u20139.","journal-title":"Biochemistry and Biophysics Reports"},{"issue":"9","key":"989_CR122","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.nutres.2011.08.007","volume":"31","author":"R Hofacer","year":"2011","unstructured":"Hofacer R, Jandacek R, Rider T, Tso P, Magrisso IJ, Benoit SC, et al. Omega-3 fatty acid deficiency selectively up-regulates delta6-desaturase expression and activity indices in rat liver: prevention by normalization of omega-3 fatty acid status. Nutr Res. 2011;31(9):715\u201322.","journal-title":"Nutr Res"},{"issue":"11","key":"989_CR123","doi-asserted-by":"publisher","first-page":"2463","DOI":"10.1194\/jlr.M700315-JLR200","volume":"48","author":"M Igarashi","year":"2007","unstructured":"Igarashi M, Ma K, Chang L, Bell JM, Rapoport SI. Dietary n-3 PUFA deprivation for 15 weeks upregulates elongase and desaturase expression in rat liver but not brain. J Lipid Res. 2007;48(11):2463\u201370.","journal-title":"J Lipid Res"},{"issue":"8","key":"989_CR124","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.3390\/nu12082183","volume":"12","author":"N Shrestha","year":"2020","unstructured":"Shrestha N, Holland OJ, Kent NL, Perkins AV, McAinch AJ, Cuffe JSM, et al. Maternal high linoleic acid alters placental fatty acid composition. Nutrients. 2020;12(8):2183\u201397.","journal-title":"Nutrients"},{"issue":"11","key":"989_CR125","doi-asserted-by":"publisher","first-page":"e0224754","DOI":"10.1371\/journal.pone.0224754","volume":"14","author":"C Kappen","year":"2019","unstructured":"Kappen C, Kruger C, Jones S, Herion NJ, Salbaum JM. Maternal diet modulates placental nutrient transporter gene expression in a mouse model of diabetic pregnancy. PLoS ONE. 2019;14(11):e0224754-e224771.","journal-title":"PLoS ONE"},{"issue":"5","key":"989_CR126","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1017\/S0007114514004346","volume":"113","author":"F Li","year":"2015","unstructured":"Li F, Duan Y, Li Y, Tang Y, Geng M, Oladele OA, et al. Effects of dietary n-6:n-3 PUFA ratio on fatty acid composition, free amino acid profile and gene expression of transporters in finishing pigs. Br J Nutr. 2015;113(5):739\u201348.","journal-title":"Br J Nutr"},{"issue":"1","key":"989_CR127","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.cccn.2003.08.002","volume":"337","author":"T Kinoshita","year":"2003","unstructured":"Kinoshita T, Shirai K, Itoh M. The level of pre-heparin serum lipoprotein lipase mass at different stages of pregnancy. Clin Chim Acta. 2003;337(1):153\u20136.","journal-title":"Clin Chim Acta"},{"issue":"6","key":"989_CR128","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1093\/ajcn\/nqz234","volume":"110","author":"SL Klingel","year":"2019","unstructured":"Klingel SL, Metherel AH, Irfan M, Rajna A, Chabowski A, Bazinet RP, et al. EPA and DHA have divergent effects on serum triglycerides and lipogenesis, but similar effects on lipoprotein lipase activity: a randomized controlled trial. Am J Clin Nutr. 2019;110(6):1502\u20139.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"989_CR129","doi-asserted-by":"publisher","first-page":"315s","DOI":"10.1093\/ajcn\/71.1.315S","volume":"71","author":"AK Dutta-Roy","year":"2000","unstructured":"Dutta-Roy AK. Transport mechanisms for long-chain polyunsaturated fatty acids in the human placenta. Am J Clin Nutr. 2000;71(1):315s-s322.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"989_CR130","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/molehr\/gal001","volume":"12","author":"B Vasarhelyi","year":"2006","unstructured":"Vasarhelyi B, Cseh A, Kocsis I, Treszl A, Gyorffy B, Rigo J Jr. Three mechanisms in the pathogenesis of pre-eclampsia suggested by over-represented transcription factor-binding sites detected with comparative promoter analysis. Mol Hum Reprod. 2006;12(1):31\u20134.","journal-title":"Mol Hum Reprod"},{"issue":"8","key":"989_CR131","first-page":"747","volume":"42","author":"AK Duttaroy","year":"2004","unstructured":"Duttaroy AK. Fetal growth and development: roles of fatty acid transport proteins and nuclear transcription factors in human placenta. Indian J Exp Biol. 2004;42(8):747\u201357.","journal-title":"Indian J Exp Biol"},{"issue":"12","key":"989_CR132","first-page":"1190","volume":"1791","author":"G Howell","year":"2009","unstructured":"Howell G, Deng X, Yellaturu C, Park EA, Wilcox HG, Raghow R, et al. N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXR\u03b1. Biochim et Biophys Acta (BBA) \u2013 Mol Cell Biol Lipids. 2009;1791(12):1190\u20136.","journal-title":"Biochim et Biophys Acta (BBA) \u2013 Mol Cell Biol Lipids"},{"key":"989_CR133","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.placenta.2021.04.009","volume":"109","author":"A G\u00f3mez-Vilarrubla","year":"2021","unstructured":"G\u00f3mez-Vilarrubla A, Mas-Par\u00e9s B, D\u00edaz M, Xargay-Torrent S, Carreras-Badosa G, Jov\u00e9 M, et al. Fatty acids in the placenta of appropiate- versus small-for-gestational-age infants at term birth. Placenta. 2021;109:4\u201310.","journal-title":"Placenta"},{"issue":"38","key":"989_CR134","first-page":"1","volume":"11","author":"M S\u00e1nchez-Campillo","year":"2020","unstructured":"S\u00e1nchez-Campillo M, Ruiz-Palacios M, Ruiz-Alcaraz AJ, Prieto-S\u00e1nchez MT, Blanco-Carnero JE, Zornoza M, et al. Child head circumference and placental MFSD2a expression are associated to the level of MFSD2a in maternal blood during pregnancy. Front Endocrinol (Lausanne). 2020;11(38):1\u201311.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"8","key":"989_CR135","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1038\/ejcn.2014.104","volume":"68","author":"M Zornoza-Moreno","year":"2014","unstructured":"Zornoza-Moreno M, Fuentes-Hern\u00e1ndez S, Carri\u00f3n V, Alc\u00e1ntara-L\u00f3pez MV, Madrid JA, L\u00f3pez-Soler C, et al. Is low docosahexaenoic acid associated with disturbed rhythms and neurodevelopment in offsprings of diabetic mothers? Eur J Clin Nutr. 2014;68(8):931\u20137.","journal-title":"Eur J Clin Nutr"},{"issue":"4","key":"989_CR136","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/S0024-3205(98)00267-7","volume":"63","author":"FM Campbell","year":"1998","unstructured":"Campbell FM, Gordon MJ, Dutta-Roy AK. Placental membrane fatty acid-binding protein preferentially binds arachidonic and docosahexaenoic acids. Life Sci. 1998;63(4):235\u201340.","journal-title":"Life Sci"},{"issue":"1 Suppl","key":"989_CR137","doi-asserted-by":"publisher","first-page":"315S","DOI":"10.1093\/ajcn\/71.1.315S","volume":"71","author":"AK Dutta-Roy","year":"2000","unstructured":"Dutta-Roy AK. Transport mechanisms for long-chain polyunsaturated fatty acids in the human placenta. Am J Clin Nutr. 2000;71(1 Suppl):315S-S322.","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"989_CR138","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.clnu.2016.01.014","volume":"36","author":"MT Prieto-Sanchez","year":"2017","unstructured":"Prieto-Sanchez MT, Ruiz-Palacios M, Blanco-Carnero JE, Pagan A, Hellmuth C, Uhl O, et al. Placental MFSD2a transporter is related to decreased DHA in cord blood of women with treated gestational diabetes. Clin Nutr (Edinburgh, Scotland). 2017;36(2):513\u201321.","journal-title":"Clin Nutr (Edinburgh, Scotland)"},{"key":"989_CR139","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/978-981-15-6082-8_14","volume":"1276","author":"BH Wong","year":"2020","unstructured":"Wong BH, Silver DL. Mfsd2a: a physiologically important lysolipid transporter in the brain and eye. Adv Exp Med Biol. 2020;1276:223\u201334.","journal-title":"Adv Exp Med Biol"},{"issue":"12","key":"989_CR140","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nu12123615","volume":"12","author":"S Basak","year":"2020","unstructured":"Basak S, Mallick R, Duttaroy AK. Maternal docosahexaenoic acid status during pregnancy and its impact on infant neurodevelopment. Nutrients. 2020;12(12):1\u201325.","journal-title":"Nutrients"},{"issue":"8","key":"989_CR141","doi-asserted-by":"publisher","first-page":"e2006443","DOI":"10.1371\/journal.pbio.2006443","volume":"16","author":"JP Chan","year":"2018","unstructured":"Chan JP, Wong BH, Chin CF, Galam DLA, Foo JC, Wong LC, et al. The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain. PLoS Biol. 2018;16(8):e2006443\u201373.","journal-title":"PLoS Biol"},{"issue":"7501","key":"989_CR142","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1038\/nature13241","volume":"509","author":"LN Nguyen","year":"2014","unstructured":"Nguyen LN, Ma D, Shui G, Wong P, Cazenave-Gassiot A, Zhang X, et al. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature. 2014;509(7501):503\u20136.","journal-title":"Nature"},{"issue":"1","key":"989_CR143","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.placenta.2012.10.012","volume":"34","author":"C Toufaily","year":"2013","unstructured":"Toufaily C, Vargas A, Lemire M, Lafond J, Rassart E, Barbeau B. MFSD2a, the Syncytin-2 receptor, is important for trophoblast fusion. Placenta. 2013;34(1):85\u20138.","journal-title":"Placenta"},{"key":"989_CR144","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.3389\/fgene.2019.01050","volume":"10","author":"M Bianchi","year":"2019","unstructured":"Bianchi M, Alisi A, Fabrizi M, Vallone C, Rav\u00e0 L, Giannico R, et al. Maternal intake of n-3 polyunsaturated fatty acids during pregnancy is associated with differential methylation profiles in cord blood white cells. Front Genet. 2019;10:1050\u20139.","journal-title":"Front Genet"},{"issue":"1663","key":"989_CR145","doi-asserted-by":"publisher","first-page":"20140074","DOI":"10.1098\/rstb.2014.0074","volume":"370","author":"GE Moore","year":"2015","unstructured":"Moore GE, Ishida M, Demetriou C, Al-Olabi L, Leon LJ, Thomas AC, et al. The role and interaction of imprinted genes in human fetal growth. Philos Trans R Soc Lond B Biol Sci. 2015;370(1663):20140074\u201386.","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"10","key":"989_CR146","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1016\/j.mod.2004.05.017","volume":"121","author":"M Salas","year":"2004","unstructured":"Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, et al. Placental growth retardation due to loss of imprinting of Phlda2. Mech Dev. 2004;121(10):1199\u2013210.","journal-title":"Mech Dev"},{"issue":"4","key":"989_CR147","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/0092-8674(91)90513-X","volume":"64","author":"TM DeChiara","year":"1991","unstructured":"DeChiara TM, Robertson EJ, Efstratiadis A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell. 1991;64(4):849\u201359.","journal-title":"Cell"},{"issue":"1","key":"989_CR148","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/s13148-020-00873-x","volume":"12","author":"F Tekola-Ayele","year":"2020","unstructured":"Tekola-Ayele F, Zeng X, Ouidir M, Workalemahu T, Zhang C, Delahaye F, et al. DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases. Clin Epigenetics. 2020;12(1):78\u201392.","journal-title":"Clin Epigenetics"},{"issue":"4, Supplement","key":"989_CR149","doi-asserted-by":"publisher","first-page":"S152","DOI":"10.1016\/j.ajog.2015.06.032","volume":"213","author":"D Monk","year":"2015","unstructured":"Monk D. Genomic imprinting in the human placenta. Am J Obstet Gynecol. 2015;213(4, Supplement):S152\u201362.","journal-title":"Am J Obstet Gynecol."},{"issue":"5","key":"989_CR150","doi-asserted-by":"publisher","first-page":"a023044","DOI":"10.1101\/cshperspect.a023044","volume":"5","author":"WP Robinson","year":"2015","unstructured":"Robinson WP, Price EM. The human placental methylome. Cold Spring Harb Perspect Med. 2015;5(5):a023044-a23059.","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"9","key":"989_CR151","doi-asserted-by":"publisher","first-page":"2118","DOI":"10.3390\/ijms20092118","volume":"20","author":"M Amatruda","year":"2019","unstructured":"Amatruda M, Ippolito G, Vizzuso S, Vizzari G, Banderali G, Verduci E. Epigenetic effects of n-3 LCPUFAs: a role in pediatric metabolic syndrome. Int J Mol Sci. 2019;20(9):2118\u201333.","journal-title":"Int J Mol Sci"},{"issue":"6","key":"989_CR152","doi-asserted-by":"publisher","first-page":"e68846","DOI":"10.1371\/journal.pone.0068846","volume":"8","author":"M Oda","year":"2013","unstructured":"Oda M, Oxley D, Dean W, Reik W. Regulation of lineage specific DNA hypomethylation in mouse trophectoderm. PLoS ONE. 2013;8(6):e68846\u201359.","journal-title":"PLoS ONE"},{"issue":"1","key":"989_CR153","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1161\/01.HYP.0000250831.52876.cb","volume":"49","author":"ST Chelbi","year":"2007","unstructured":"Chelbi ST, Mondon F, Jammes H, Buffat C, Mignot TM, Tost J, et al. Expressional and epigenetic alterations of placental serine protease inhibitors: SERPINA3 is a potential marker of preeclampsia. Hypertension. 2007;49(1):76\u201383.","journal-title":"Hypertension"},{"issue":"2","key":"989_CR154","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1161\/HYPERTENSIONAHA.116.08483","volume":"69","author":"Y Jia","year":"2017","unstructured":"Jia Y, Li T, Huang X, Xu X, Zhou X, Jia L, et al. Dysregulated DNA methyltransferase 3a upregulates IGFBP5 to suppress trophoblast cell migration and invasion in preeclampsia. Hypertension. 2017;69(2):356\u201366.","journal-title":"Hypertension"},{"key":"989_CR155","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.placenta.2016.10.001","volume":"48","author":"SL Wilson","year":"2016","unstructured":"Wilson SL, Liu Y, Robinson WP. Placental telomere length decline with gestational age differs by sex and TERT, DNMT1, and DNMT3A DNA methylation. Placenta. 2016;48:26\u201333.","journal-title":"Placenta"},{"issue":"9","key":"989_CR156","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1093\/molehr\/gav037","volume":"21","author":"Y Tang","year":"2015","unstructured":"Tang Y, Liu H, Li H, Peng T, Gu W, Li X. Hypermethylation of the HLA-G promoter is associated with preeclampsia. Mol Hum Reprod. 2015;21(9):736\u201344.","journal-title":"Mol Hum Reprod"},{"key":"989_CR157","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1186\/1471-2164-14-685","volume":"14","author":"R Das","year":"2013","unstructured":"Das R, Lee YK, Strogantsev R, Jin S, Lim YC, Ng PY, et al. DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation. BMC Genomics. 2013;14:685\u201399.","journal-title":"BMC Genomics"},{"issue":"2","key":"989_CR158","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1111\/j.1399-0004.2010.01443.x","volume":"79","author":"DK Bourque","year":"2011","unstructured":"Bourque DK, Pe\u00f1aherrera MS, Yuen RK, Van Allen MI, McFadden DE, Robinson WP. The utility of quantitative methylation assays at imprinted genes for the diagnosis of fetal and placental disorders. Clin Genet. 2011;79(2):169\u201375.","journal-title":"Clin Genet"},{"issue":"1","key":"989_CR159","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1756-8935-4-10","volume":"4","author":"RK Yuen","year":"2011","unstructured":"Yuen RK, Jiang R, Pe\u00f1aherrera MS, McFadden DE, Robinson WP. Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies. Epigenetics Chromatin. 2011;4(1):10\u201326.","journal-title":"Epigenetics Chromatin"},{"key":"989_CR160","doi-asserted-by":"publisher","first-page":"285","DOI":"10.3389\/fgene.2013.00285","volume":"4","author":"B Novakovic","year":"2013","unstructured":"Novakovic B, Saffery R. Placental pseudo-malignancy from a DNA methylation perspective: unanswered questions and future directions. Front Genet. 2013;4:285\u201392.","journal-title":"Front Genet"},{"issue":"7394","key":"989_CR161","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/nature10960","volume":"484","author":"ZD Smith","year":"2012","unstructured":"Smith ZD, Chan MM, Mikkelsen TS, Gu H, Gnirke A, Regev A, et al. A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature. 2012;484(7394):339\u201344.","journal-title":"Nature"},{"issue":"13","key":"989_CR162","doi-asserted-by":"publisher","first-page":"9583","DOI":"10.1074\/jbc.M109.064956","volume":"285","author":"B Novakovic","year":"2010","unstructured":"Novakovic B, Wong NC, Sibson M, Ng HK, Morley R, Manuelpillai U, et al. DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. J Biol Chem. 2010;285(13):9583\u201393.","journal-title":"J Biol Chem"},{"issue":"1","key":"989_CR163","doi-asserted-by":"publisher","first-page":"5095","DOI":"10.1038\/s41467-021-24558-y","volume":"12","author":"TM Everson","year":"2021","unstructured":"Everson TM, Vives-Usano M, Seyve E, Cardenas A, Lacasa\u00f1a M, Craig JM, et al. Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth. Nat Commun. 2021;12(1):5095\u2013108.","journal-title":"Nat Commun"},{"issue":"1","key":"989_CR164","doi-asserted-by":"publisher","first-page":"5592","DOI":"10.1038\/ncomms6592","volume":"5","author":"EW Tobi","year":"2014","unstructured":"Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, et al. DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nat Commun. 2014;5(1):5592\u2013606.","journal-title":"Nat Commun"},{"key":"989_CR165","doi-asserted-by":"crossref","unstructured":"Duttaroy AK, Basak S. Placental epigenetics and its importance in placental development. Early nutrition and lifestyle factors: effects on first trimester placenta. Cham: Springer International Publishing; 2016. pp. 129\u201337.","DOI":"10.1007\/978-3-319-38804-5_10"},{"issue":"11","key":"989_CR166","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.nutres.2015.09.005","volume":"35","author":"CL Cheatham","year":"2015","unstructured":"Cheatham CL, Lupu DS, Niculescu MD. Genetic and epigenetic transgenerational implications related to omega-3 fatty acids. Part II: maternal FADS2 rs174575 genotype and DNA methylation predict toddler cognitive performance. Nutr Res. 2015;35(11):948\u201355.","journal-title":"Nutr Res."},{"issue":"5","key":"989_CR167","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1038\/ejhg.2014.139","volume":"23","author":"S Voisin","year":"2015","unstructured":"Voisin S, Alm\u00e9n MS, Moschonis G, Chrousos GP, Manios Y, Schi\u00f6th HB. Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents. Eur J Human Gen\u202f: EJHG. 2015;23(5):654\u201362.","journal-title":"Eur J Human Gen : EJHG"},{"issue":"10","key":"989_CR168","doi-asserted-by":"publisher","first-page":"e109896","DOI":"10.1371\/journal.pone.0109896","volume":"9","author":"SP Hoile","year":"2014","unstructured":"Hoile SP, Clarke-Harris R, Huang R-C, Calder PC, Mori TA, Beilin LJ, et al. Supplementation with N-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells. PLoS ONE. 2014;9(10):e109896\u2013909.","journal-title":"PLoS ONE"},{"issue":"2","key":"989_CR169","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1097\/MCO.0000000000000023","volume":"17","author":"GC Burdge","year":"2014","unstructured":"Burdge GC, Lillycrop KA. Fatty acids and epigenetics. Curr Opin Clin Nutr Metab Care. 2014;17(2):156\u201361.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"1","key":"989_CR170","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s13148-018-0480-5","volume":"10","author":"E Rahbar","year":"2018","unstructured":"Rahbar E, Waits CMK, Kirby EH, Miller LR, Ainsworth HC, Cui T, et al. Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes. Clin Epigenetics. 2018;10(1):46\u201356.","journal-title":"Clin Epigenetics"},{"issue":"13","key":"989_CR171","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1002\/pros.23205","volume":"76","author":"T Cui","year":"2016","unstructured":"Cui T, Hester AG, Seeds MC, Rahbar E, Howard TD, Sergeant S, et al. Impact of genetic and epigenetic variations within the FADS cluster on the composition and metabolism of polyunsaturated fatty acids in prostate cancer. Prostate. 2016;76(13):1182\u201391.","journal-title":"Prostate"},{"issue":"1","key":"989_CR172","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s13148-017-0345-3","volume":"9","author":"BL Tremblay","year":"2017","unstructured":"Tremblay BL, Gu\u00e9nard F, Rudkowska I, Lemieux S, Couture P, Vohl M-C. Epigenetic changes in blood leukocytes following an omega-3 fatty acid supplementation. Clin Epigenetics. 2017;9(1):43\u201352.","journal-title":"Clin Epigenetics"},{"issue":"2","key":"989_CR173","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1002\/mnfr.201500436","volume":"60","author":"Y Ma","year":"2016","unstructured":"Ma Y, Smith CE, Lai C-Q, Irvin MR, Parnell LD, Lee Y-C, et al. The effects of omega-3 polyunsaturated fatty acids and genetic variants on methylation levels of the interleukin-6 gene promoter. Mol Nutr Food Res. 2016;60(2):410\u20139.","journal-title":"Mol Nutr Food Res"},{"issue":"92","key":"989_CR174","first-page":"1","volume":"6","author":"F Haghighi","year":"2015","unstructured":"Haghighi F, Galfalvy H, Chen S, Huang Y-Y, Cooper TB, Burke AK, et al. DNA methylation perturbations in genes involved in polyunsaturated fatty acid biosynthesis associated with depression and suicide risk. Frontiers in Neurology. 2015;6(92):1\u20137.","journal-title":"Frontiers in Neurology."},{"issue":"6","key":"989_CR175","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/lipd.12074","volume":"53","author":"B Ramaiyan","year":"2018","unstructured":"Ramaiyan B, Talahalli RR. Dietary unsaturated fatty acids modulate maternal dyslipidemia-induced DNA methylation and histone acetylation in placenta and fetal liver in rats. Lipids. 2018;53(6):581\u20138.","journal-title":"Lipids"},{"issue":"4","key":"989_CR176","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.3945\/ajcn.117.155648","volume":"106","author":"M Karimi","year":"2017","unstructured":"Karimi M, Vedin I, Freund Levi Y, Basun H, Fax\u00e9n Irving G, Eriksdotter M, et al. DHA-rich n\u20133 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study. Am J Clin Nutr. 2017;106(4):1157\u201365.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"989_CR177","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1038\/s41598-020-57725-0","volume":"10","author":"SE Dwi Putra","year":"2020","unstructured":"Dwi Putra SE, Reichetzeder C, Hasan AA, Slowinski T, Chu C, Kr\u00e4mer BK, et al. Being born large for gestational age is associated with increased global placental DNA methylation. Sci Rep. 2020;10(1):927\u201337.","journal-title":"Sci Rep"},{"issue":"9","key":"989_CR178","doi-asserted-by":"publisher","first-page":"e1229","DOI":"10.1038\/tp.2017.182","volume":"7","author":"M Maekawa","year":"2017","unstructured":"Maekawa M, Watanabe A, Iwayama Y, Kimura T, Hamazaki K, Balan S, et al. Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes. Transl Psychiatry. 2017;7(9):e1229\u201340.","journal-title":"Transl Psychiatry"},{"issue":"9","key":"989_CR179","doi-asserted-by":"publisher","first-page":"3703","DOI":"10.1096\/fj.11-203323","volume":"26","author":"SK Huang","year":"2012","unstructured":"Huang SK, Scruggs AM, Donaghy J, McEachin RC, Fisher AS, Richardson BC, et al. Prostaglandin E2 increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression. FASEB journal\u202f: official publication of the Federation of American Societies for Experimental Biology. 2012;26(9):3703\u201314.","journal-title":"FASEB journal : official publication of the Federation of American Societies for Experimental Biology"},{"issue":"4","key":"989_CR180","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3945\/jn.113.187203","volume":"144","author":"S Aslibekyan","year":"2014","unstructured":"Aslibekyan S, Wiener HW, Havel PJ, Stanhope KL, O\u2019Brien DM, Hopkins SE, et al. DNA methylation patterns are associated with n-3 fatty acid intake in Yup\u2019ik people. J Nutr. 2014;144(4):425\u201330.","journal-title":"J Nutr"},{"issue":"1","key":"989_CR181","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s13148-018-0545-5","volume":"10","author":"Z He","year":"2018","unstructured":"He Z, Zhang R, Jiang F, Zhang H, Zhao A, Xu B, et al. FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression. Clin Epigenetics. 2018;10(1):113\u201326.","journal-title":"Clin Epigenetics"},{"issue":"1","key":"989_CR182","doi-asserted-by":"publisher","first-page":"34857","DOI":"10.1038\/srep34857","volume":"6","author":"EH Marchlewicz","year":"2016","unstructured":"Marchlewicz EH, Dolinoy DC, Tang L, Milewski S, Jones TR, Goodrich JM, et al. Lipid metabolism is associated with developmental epigenetic programming. Sci Rep. 2016;6(1):34857\u201370.","journal-title":"Sci Rep"},{"issue":"10","key":"989_CR183","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.placenta.2004.11.010","volume":"26","author":"LP Reynolds","year":"2005","unstructured":"Reynolds LP, Borowicz PP, Vonnahme KA, Johnson ML, Grazul-Bilska AT, Wallace JM, et al. Animal models of placental angiogenesis. Placenta. 2005;26(10):689\u2013708.","journal-title":"Placenta"},{"issue":"1","key":"989_CR184","doi-asserted-by":"publisher","first-page":"329","DOI":"10.3390\/ijms21010329","volume":"21","author":"V Gagn\u00e9-Ouellet","year":"2020","unstructured":"Gagn\u00e9-Ouellet V, Breton E, Thibeault K, Fortin CA, Cardenas A, Gu\u00e9rin R, et al. Mediation analysis supports a causal relationship between maternal hyperglycemia and placental DNA methylation variations at the leptin gene locus and cord blood leptin levels. Int J Mol Sci. 2020;21(1):329\u201340.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"989_CR185","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1093\/hmg\/ddz287","volume":"29","author":"MN Leseva","year":"2020","unstructured":"Leseva MN, Binder AM, Ponsonby AL, Vuillermin P, Saffery R, Michels KB. Differential gene expression and limited epigenetic dysregulation at the materno-fetal interface in preeclampsia. Hum Mol Genet. 2020;29(2):335\u201350.","journal-title":"Hum Mol Genet"},{"issue":"2","key":"989_CR186","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1093\/humrep\/dex366","volume":"33","author":"C Choux","year":"2018","unstructured":"Choux C, Binquet C, Carmignac V, Bruno C, Chapusot C, Barberet J, et al. The epigenetic control of transposable elements and imprinted genes in newborns is affected by the mode of conception: ART versus spontaneous conception without underlying infertility. Hum Reprod. 2018;33(2):331\u201340.","journal-title":"Hum Reprod"},{"issue":"6","key":"989_CR187","doi-asserted-by":"publisher","first-page":"e0179934","DOI":"10.1371\/journal.pone.0179934","volume":"12","author":"S Blazevic","year":"2017","unstructured":"Blazevic S, Horvaticek M, Kesic M, Zill P, Hranilovic D, Ivanisevic M, et al. Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus. PLoS ONE. 2017;12(6):e0179934-e179950.","journal-title":"PLoS ONE"},{"issue":"6","key":"989_CR188","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1159\/000366386","volume":"34","author":"L Liu","year":"2014","unstructured":"Liu L, Zhang X, Rong C, Rui C, Ji H, Qian YJ, et al. Distinct DNA methylomes of human placentas between pre-eclampsia and gestational diabetes mellitus. Cell Physiol Biochem\u202f: international journal of experimental cellular physiology, biochemistry, and pharmacology. 2014;34(6):1877\u201389.","journal-title":"Cell Physiol Biochem : international journal of experimental cellular physiology, biochemistry, and pharmacology"},{"key":"989_CR189","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1186\/1471-2164-12-529","volume":"12","author":"B Novakovic","year":"2011","unstructured":"Novakovic B, Yuen RK, Gordon L, Penaherrera MS, Sharkey A, Moffett A, et al. Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental\/stochastic factors. BMC Genomics. 2011;12:529\u201343.","journal-title":"BMC Genomics"},{"issue":"Pt B","key":"989_CR190","doi-asserted-by":"publisher","first-page":"105255","DOI":"10.1016\/j.envint.2019.105255","volume":"133","author":"Y Zhao","year":"2019","unstructured":"Zhao Y, Song Q, Ge W, Jin Y, Chen S, Zhao Y, et al. Associations between in utero exposure to polybrominated diphenyl ethers, pathophysiological state of fetal growth and placental DNA methylation changes. Environ Int. 2019;133(Pt B):105255\u201363.","journal-title":"Environ Int"},{"key":"989_CR191","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.etap.2017.11.007","volume":"57","author":"S Fa","year":"2018","unstructured":"Fa S, Larsen TV, Bilde K, Daugaard TF, Ernst EH, Lykke-Hartmann K, et al. Changes in first trimester fetal CYP1A1 and AHRR DNA methylation and mRNA expression in response to exposure to maternal cigarette smoking. Environ Toxicol Pharmacol. 2018;57:19\u201327.","journal-title":"Environ Toxicol Pharmacol"},{"issue":"3","key":"989_CR192","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1093\/ajcn\/nqz311","volume":"111","author":"SL Robinson","year":"2020","unstructured":"Robinson SL, Mumford SL, Guan W, Zeng X, Kim K, Radoc JG, et al. Maternal fatty acid concentrations and newborn DNA methylation. Am J Clin Nutr. 2020;111(3):613\u201321.","journal-title":"Am J Clin Nutr"},{"key":"989_CR193","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/s13148-016-0281-7","volume":"8","author":"SJ van Dijk","year":"2016","unstructured":"van Dijk SJ, Zhou J, Peters TJ, Buckley M, Sutcliffe B, Oytam Y, et al. Effect of prenatal DHA supplementation on the infant epigenome: results from a randomized controlled trial. Clin Epigenetics. 2016;8:114\u201327.","journal-title":"Clin Epigenetics"},{"issue":"2","key":"989_CR194","doi-asserted-by":"publisher","first-page":"480","DOI":"10.3945\/ajcn.112.052241","volume":"98","author":"HS Lee","year":"2013","unstructured":"Lee HS, Barraza-Villarreal A, Hernandez-Vargas H, Sly PD, Biessy C, Ramakrishnan U, et al. Modulation of DNA methylation states and infant immune system by dietary supplementation with omega-3 PUFA during pregnancy in an intervention study. Am J Clin Nutr. 2013;98(2):480\u20137.","journal-title":"Am J Clin Nutr"},{"issue":"23","key":"989_CR195","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1152\/physiolgenomics.00061.2014","volume":"46","author":"H-S Lee","year":"2014","unstructured":"Lee H-S, Barraza-Villarreal A, Biessy C, Duarte-Salles T, Sly PD, Ramakrishnan U, et al. Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2\/H19 imprinted genes and growth of infants. Physiol Genomics. 2014;46(23):851\u20137.","journal-title":"Physiol Genomics"},{"issue":"1","key":"989_CR196","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1038\/s41380-019-0580-4","volume":"25","author":"V Cinquina","year":"2020","unstructured":"Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, et al. Life-long epigenetic programming of cortical architecture by maternal \u2018Western\u2019 diet during pregnancy. Mol Psychiatry. 2020;25(1):22\u201336.","journal-title":"Mol Psychiatry"},{"issue":"9","key":"989_CR197","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/j.nutres.2016.06.005","volume":"36","author":"C Fan","year":"2016","unstructured":"Fan C, Fu H, Dong H, Lu Y, Lu Y, Qi K. Maternal n-3 polyunsaturated fatty acid deprivation during pregnancy and lactation affects neurogenesis and apoptosis in adult offspring: associated with DNA methylation of brain-derived neurotrophic factor transcripts. Nutr Res. 2016;36(9):1013\u201321.","journal-title":"Nutr Res"},{"issue":"1","key":"989_CR198","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1096\/fj.12-210724","volume":"27","author":"MD Niculescu","year":"2013","unstructured":"Niculescu MD, Lupu DS, Craciunescu CN. Perinatal manipulation of alpha-linolenic acid intake induces epigenetic changes in maternal and offspring livers. FASEB J\u202f: official publication of the Federation of American Societies for Experimental Biology. 2013;27(1):350\u20138.","journal-title":"FASEB J : official publication of the Federation of American Societies for Experimental Biology"}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-022-00989-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-022-00989-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-022-00989-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T13:22:34Z","timestamp":1678108954000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-022-00989-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,8]]},"references-count":198,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["989"],"URL":"https:\/\/doi.org\/10.1007\/s43032-022-00989-w","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,8]]},"assertion":[{"value":"9 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}