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Significant difference was found in the detection rate of YCM between the azoospermia group and the oligospermia group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Of all types of YCM, the highest detection rate was AZFc (<jats:italic>n<\/jats:italic>\u2009=\u200983), followed by AZFb\u2009+\u2009c (<jats:italic>n<\/jats:italic>\u2009=\u200928). 264 cases (16.54%) of sex chromosomal aberrations were detected. The most prevalent karyotype was 47, XXY (<jats:italic>n<\/jats:italic>\u2009=\u2009202). The detection rate of sex chromosomal aberrations in azoospermia group was higher than that in severe oligospermia group and oligospermia group, and the differences were significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). 28 cases (1.57%) of autosomal aberrations and 105 cases (6.58%) of chromosomal polymorphism were identified. The current research has some limitations due to the lack of normal men as the control group but suggests that YCM and chromosomal aberrations represent key genetic factors influencing spermatogenesis in infertile males of Zhuang ethnicity in Guangxi.<\/jats:p>","DOI":"10.1007\/s43032-024-01568-x","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T15:01:59Z","timestamp":1717599719000},"page":"3074-3085","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Analysis of Y Chromosome Microdeletions and Chromosomal Aberrations in 1596 Male Infertility Patients of the Zhuang Ethnic Group in Guangxi"],"prefix":"10.1007","volume":"31","author":[{"given":"Mingfang","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengjun","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaosheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibing","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningyu","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5681-8838","authenticated-orcid":false,"given":"Jianghui","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,5]]},"reference":[{"issue":"4","key":"1568_CR1","doi-asserted-by":"publisher","first-page":"hoac051","DOI":"10.1093\/hropen\/hoac051","volume":"2022","author":"CM Cox","year":"2022","unstructured":"Cox CM, Thoma ME, Tchangalova N, et al. 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