{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:51:19Z","timestamp":1793825479875,"version":"4.6.1"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>The investigation about association between vitamin D level and clinical outcomes of assisted reproductive treatment showed various outcomes. This study aimed to review the correlation between vitamin D and outcomes of assisted reproductive treatment. The search was registered on the PROSPERO database (CRD42023458040). PubMed, Embase, Medline, ClinicalTrials.gov, and Cochrane databases were searched up to July 2023. Twenty-three observational studies were selected for meta-analysis. Comparing groups with deficient and \u2018insufficient\u2009+\u2009sufficient\u2019 vitamin D level, meta-analysis showed positive correlation between clinical pregnancy rate and vitamin D (OR 0.81, 95%CI: 0.70, 0.95, <jats:italic>P<\/jats:italic>\u2009=\u20090.0001). Comparing groups with \u2018deficient\u2009+\u2009insufficient\u2019 and sufficient vitamin D level, meta-analysis showed positive correlation between vitamin D and clinical pregnancy rate (OR 0.71, 95%CI: 0.55, 0.91, <jats:italic>P<\/jats:italic>\u2009=\u20090.006), vitamin D and live birth rate (OR 0.69, 95%CI: 0.54, 0.89, <jats:italic>P<\/jats:italic>\u2009=\u20090.003). Subgroup analysis did not show the source of high heterogeneity. No correlation was found in biochemical pregnancy rate, ongoing pregnancy rate, miscarriage rate and implantation rate. In dose-response meta-analysis, a nonlinear association was found between vitamin D levels and outcomes when levels are below approximately 24 ng\/L. The study shows that vitamin D level is associated with clinical pregnancy rate and live birth rate. Low vitamin D level does not influence biochemical pregnancy rate, ongoing pregnancy rate, miscarriage rate and implantation rate. Furthermore, 24 ng\/L may be a possible threshold of vitamin D concentration in assisted reproduction therapy.<\/jats:p>","DOI":"10.1007\/s43032-024-01578-9","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T18:02:12Z","timestamp":1716400932000},"page":"1446-1458","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Association Between Vitamin D Level and Clinical Outcomes of Assisted Reproductive Treatment: A Systematic Review and Dose-Response Meta-Analysis"],"prefix":"10.1007","volume":"32","author":[{"given":"Chenhao","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinqi","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiumei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxiao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanling","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6499-4233","authenticated-orcid":false,"given":"Ying","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6653-4529","authenticated-orcid":false,"given":"Dongzhi","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"issue":"2","key":"1578_CR1","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.fertnstert.2014.04.046","volume":"102","author":"M Irani","year":"2014","unstructured":"Irani M, Merhi Z. Role of vitamin D in ovarian physiology and its implication in reproduction: a systematic review. Fertil Steril. 2014;102(2):460\u2013e4683.","journal-title":"Fertil Steril"},{"issue":"10","key":"1578_CR2","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.1093\/humrep\/deac155","volume":"37","author":"A Subramanian","year":"2022","unstructured":"Subramanian A, et al. Preconception vitamin D and miscarriage in a prospective cohort study. Hum Reprod. 2022;37(10):2465\u201373.","journal-title":"Hum Reprod"},{"key":"1578_CR3","doi-asserted-by":"crossref","unstructured":"Du H et al. Direct regulation of HOXA10 by 1,25-(OH)2D3 in human myelomonocytic cells and human endometrial stromal cells. Mol Endocrinol. 2005;19(9):2222\u201333.","DOI":"10.1210\/me.2004-0336"},{"issue":"2","key":"1578_CR4","doi-asserted-by":"publisher","first-page":"E77","DOI":"10.9778\/cmajo.20120032","volume":"1","author":"K Garbedian","year":"2013","unstructured":"Garbedian K, et al. Effect of vitamin D status on clinical pregnancy rates following in vitro fertilization. CMAJ Open. 2013;1(2):E77\u201382.","journal-title":"CMAJ Open"},{"issue":"4","key":"1578_CR5","first-page":"280","volume":"15","author":"GH Neysanian","year":"2021","unstructured":"Neysanian GH, et al. The effects of serum and follicular fluid vitamin D levels on assisted Reproductive techniques: a prospective cohort study. Int J Fertil Steril. 2021;15(4):280\u20135.","journal-title":"Int J Fertil Steril"},{"issue":"11","key":"1578_CR6","doi-asserted-by":"publisher","first-page":"E2372","DOI":"10.1210\/jc.2014-1802","volume":"99","author":"A Paffoni","year":"2014","unstructured":"Paffoni A, et al. Vitamin D deficiency and infertility: insights from in vitro fertilization cycles. J Clin Endocrinol Metab. 2014;99(11):E2372\u20136.","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"1578_CR7","doi-asserted-by":"publisher","first-page":"2032","DOI":"10.1093\/humrep\/deu156","volume":"29","author":"NP Polyzos","year":"2014","unstructured":"Polyzos NP, et al. Vitamin D deficiency and pregnancy rates in women undergoing single embryo, blastocyst stage, transfer (SET) for IVF\/ICSI. Hum Reprod. 2014;29(9):2032\u201340.","journal-title":"Hum Reprod"},{"issue":"2","key":"1578_CR8","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.fertnstert.2013.10.008","volume":"101","author":"BJ Rudick","year":"2014","unstructured":"Rudick BJ, et al. Influence of vitamin D levels on in vitro fertilization outcomes in donor-recipient cycles. Fertil Steril. 2014;101(2):447\u201352.","journal-title":"Fertil Steril"},{"issue":"1","key":"1578_CR9","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s00404-013-2959-9","volume":"289","author":"RD Firouzabadi","year":"2014","unstructured":"Firouzabadi RD, et al. Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program. Arch Gynecol Obstet. 2014;289(1):201\u20136.","journal-title":"Arch Gynecol Obstet"},{"issue":"3","key":"1578_CR10","doi-asserted-by":"publisher","first-page":"e3151","DOI":"10.1016\/j.ajog.2014.09.029","volume":"212","author":"JM Franasiak","year":"2015","unstructured":"Franasiak JM, et al. Vitamin D levels do not affect IVF outcomes following the transfer of euploid blastocysts. Am J Obstet Gynecol. 2015;212(3):e3151\u20136.","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"1578_CR11","first-page":"221","volume":"20","author":"R Hosseinisadat","year":"2021","unstructured":"Hosseinisadat R, et al. Assessment of the effect of serum and follicular fluid vitamin D and glucose on assisted reproductive technique outcome: a cross-sectional study. Int J Reprod Biomed. 2021;20(3):221\u201330.","journal-title":"Int J Reprod Biomed"},{"issue":"5","key":"1578_CR12","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.rbmo.2018.12.036","volume":"38","author":"L Jiang","year":"2019","unstructured":"Jiang L, et al. The effect of serum vitamin D levels in couples on embryo development and clinical outcomes. Reprod Biomed Online. 2019;38(5):699\u2013710.","journal-title":"Reprod Biomed Online"},{"key":"1578_CR13","doi-asserted-by":"crossref","unstructured":"Ko JKY et al. 100 years of vitamin D: Effect of serum vitamin D level before ovarian stimulation on the cumulative live birth rate of women undergoing in vitro fertilization: a retrospective analysis. Endocr Connect. 2022;11(2).","DOI":"10.1530\/EC-21-0444"},{"issue":"8","key":"1578_CR14","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1093\/humrep\/dew107","volume":"31","author":"A van de Vijver","year":"2016","unstructured":"van de Vijver A, et al. Vitamin D deficiency and pregnancy rates following frozen-thawed embryo transfer: a prospective cohort study. Hum Reprod. 2016;31(8):1749\u201354.","journal-title":"Hum Reprod"},{"issue":"3","key":"1578_CR15","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1111\/jog.15521","volume":"49","author":"Z Yu","year":"2023","unstructured":"Yu Z, et al. Does vitamin D level associate with pregnancy outcomes in Chinese women undergoing in vitro fertilization\/intracytoplasmic sperm injection-embryo transfer? A retrospective cohort study. J Obstet Gynaecol Res. 2023;49(3):835\u201345.","journal-title":"J Obstet Gynaecol Res"},{"issue":"3","key":"1578_CR16","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/j.fertnstert.2020.09.005","volume":"115","author":"S Cai","year":"2021","unstructured":"Cai S, et al. Impact of vitamin D on human embryo implantation-a prospective cohort study in women undergoing fresh embryo transfer. Fertil Steril. 2021;115(3):655\u201364.","journal-title":"Fertil Steril"},{"key":"1578_CR17","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/1477-7827-8-91","volume":"8","author":"GM Anifandis","year":"2010","unstructured":"Anifandis GM, et al. Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome. Reprod Biol Endocrinol. 2010;8:91.","journal-title":"Reprod Biol Endocrinol"},{"issue":"1","key":"1578_CR18","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/s12958-019-0500-0","volume":"17","author":"X Liu","year":"2019","unstructured":"Liu X, et al. Effect of vitamin D status on normal fertilization rate following in vitro fertilization. Reprod Biol Endocrinol. 2019;17(1):59.","journal-title":"Reprod Biol Endocrinol"},{"issue":"6","key":"1578_CR19","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/j.rbmo.2020.08.014","volume":"41","author":"NL Walz","year":"2020","unstructured":"Walz NL, et al. Serum vitamin D status is associated with increased blastocyst development rate in women undergoing IVF. Reprod Biomed Online. 2020;41(6):1101\u201311.","journal-title":"Reprod Biomed Online"},{"issue":"7","key":"1578_CR20","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1210\/jc.2011-0385","volume":"96","author":"MF Holick","year":"2011","unstructured":"Holick MF, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911\u201330.","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"1578_CR21","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1210\/jc.2011-2218","volume":"97","author":"CJ Rosen","year":"2012","unstructured":"Rosen CJ, et al. IOM committee members respond to Endocrine Society vitamin D guideline. J Clin Endocrinol Metab. 2012;97(4):1146\u201352.","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"1578_CR22","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1097\/XEB.0000000000000132","volume":"16","author":"C Xu","year":"2018","unstructured":"Xu C, Doi SAR. The robust error meta-regression method for dose\u2013response meta-analysis. Int J Evid Based Healthc. 2018;16(3):138\u201344.","journal-title":"Int J Evid Based Healthc"},{"key":"1578_CR23","doi-asserted-by":"crossref","unstructured":"Bagnardi V et al. Light alcohol drinking and cancer: a meta-anal-ysis. Ann Oncol. 2013;24(2):301\u2013308.","DOI":"10.1093\/annonc\/mds337"},{"key":"1578_CR24","doi-asserted-by":"crossref","unstructured":"Aune D et al. Maternal body mass index and the risk of fetal death, stillbirth, and infant death: a systematic review and meta-analysis . JAMA. 2014;311(15):1536\u201346.","DOI":"10.1001\/jama.2014.2269"},{"issue":"3","key":"1578_CR25","doi-asserted-by":"publisher","first-page":"729","DOI":"10.3945\/ajcn.115.126359","volume":"104","author":"L Abadia","year":"2016","unstructured":"Abadia L, et al. Serum 25-hydroxyvitamin D concentrations and treatment outcomes of women undergoing assisted reproduction. Am J Clin Nutr. 2016;104(3):729\u201335.","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"1578_CR26","doi-asserted-by":"publisher","first-page":"79","DOI":"10.4103\/jhrs.JHRS_117_16","volume":"10","author":"M Banker","year":"2017","unstructured":"Banker M, Sorathiya D, Shah S. Vitamin D Deficiency does not Influence Reproductive outcomes of IVF-ICSI: a study of oocyte donors and recipients. J Hum Reprod Sci. 2017;10(2):79\u201385.","journal-title":"J Hum Reprod Sci"},{"issue":"1","key":"1578_CR27","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s12978-019-0769-7","volume":"16","author":"J Chu","year":"2019","unstructured":"Chu J, et al. Vitamin D and assisted reproductive treatment outcome: a prospective cohort study. Reprod Health. 2019;16(1):106.","journal-title":"Reprod Health"},{"issue":"7","key":"1578_CR28","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1007\/s10815-018-1179-4","volume":"35","author":"P Ciepiela","year":"2018","unstructured":"Ciepiela P, et al. Vitamin D as a follicular marker of human oocyte quality and a serum marker of in vitro fertilization outcome. J Assist Reprod Genet. 2018;35(7):1265\u201376.","journal-title":"J Assist Reprod Genet"},{"issue":"6","key":"1578_CR29","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1016\/j.fertnstert.2014.08.030","volume":"102","author":"A Fabris","year":"2014","unstructured":"Fabris A, et al. Impact of circulating levels of total and bioavailable serum vitamin D on pregnancy rate in egg donation recipients. Fertil Steril. 2014;102(6):1608\u201312.","journal-title":"Fertil Steril"},{"issue":"2","key":"1578_CR30","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.rbmo.2017.05.009","volume":"35","author":"AM Fabris","year":"2017","unstructured":"Fabris AM, et al. Impact of vitamin D levels on ovarian reserve and ovarian response to ovarian stimulation in oocyte donors. Reprod Biomed Online. 2017;35(2):139\u201344.","journal-title":"Reprod Biomed Online"},{"issue":"4","key":"1578_CR31","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.eprac.2023.01.005","volume":"29","author":"HA Hasan","year":"2023","unstructured":"Hasan HA, et al. Preconception Vitamin D Level and in Vitro fertilization: pregnancy outcome. Endocr Pract. 2023;29(4):235\u20139.","journal-title":"Endocr Pract"},{"issue":"2","key":"1578_CR32","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1007\/s00404-021-06174-9","volume":"305","author":"KP Muyayalo","year":"2022","unstructured":"Muyayalo KP, et al. Low vitamin D levels in follicular fluid, but not in serum, are associated with adverse outcomes in assisted reproduction. Arch Gynecol Obstet. 2022;305(2):505\u201317.","journal-title":"Arch Gynecol Obstet"},{"issue":"11","key":"1578_CR33","doi-asserted-by":"publisher","first-page":"3321","DOI":"10.1093\/humrep\/des280","volume":"27","author":"B Rudick","year":"2012","unstructured":"Rudick B, et al. Characterizing the influence of vitamin D levels on IVF outcomes. Hum Reprod. 2012;27(11):3321\u20137.","journal-title":"Hum Reprod"},{"key":"1578_CR34","doi-asserted-by":"crossref","unstructured":"VanderWeele TJ, Ding P. Sensitivity analysis in observational research: introducing the E-Value. Ann Intern Med. 2017;167(4):268\u2013274.","DOI":"10.7326\/M16-2607"},{"issue":"1","key":"1578_CR35","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12958-018-0324-3","volume":"16","author":"J Zhao","year":"2018","unstructured":"Zhao J, et al. Whether vitamin D was associated with clinical outcome after IVF\/ICSI: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2018;16(1):13.","journal-title":"Reprod Biol Endocrinol"},{"issue":"5","key":"1578_CR36","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1016\/j.fertnstert.2020.05.040","volume":"114","author":"M Cozzolino","year":"2020","unstructured":"Cozzolino M, et al. How vitamin D level influences in vitro fertilization outcomes: results of a systematic review and meta-analysis. Fertil Steril. 2020;114(5):1014\u201325.","journal-title":"Fertil Steril"},{"issue":"2","key":"1578_CR37","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1080\/14647273.2020.1807618","volume":"25","author":"F Iliuta","year":"2022","unstructured":"Iliuta F, et al. Women\u2019s vitamin D levels and IVF results: a systematic review of the literature and meta-analysis, considering three categories of vitamin status (replete, insufficient and deficient). Hum Fertil (Camb). 2022;25(2):228\u201346.","journal-title":"Hum Fertil (Camb)"},{"issue":"6","key":"1578_CR38","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1007\/s00404-016-4058-1","volume":"293","author":"SS Lv","year":"2016","unstructured":"Lv SS, et al. Serum vitamin D status and in vitro fertilization outcomes: a systematic review and meta-analysis. Arch Gynecol Obstet. 2016;293(6):1339\u201345.","journal-title":"Arch Gynecol Obstet"},{"issue":"4","key":"1578_CR39","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.rbmo.2012.12.012","volume":"26","author":"A Velthut","year":"2013","unstructured":"Velthut A, et al. Elevated blood plasma antioxidant status is favourable for achieving IVF\/ICSI pregnancy. Reprod Biomed Online. 2013;26(4):345\u201352.","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"1578_CR40","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s00404-013-2959-9","volume":"289","author":"RD Firouzabadi","year":"2013","unstructured":"Firouzabadi RD, et al. Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program. Arch Gynecol Obstet. 2013;289(1):201\u20136.","journal-title":"Arch Gynecol Obstet"},{"issue":"6","key":"1578_CR41","doi-asserted-by":"publisher","first-page":"4139","DOI":"10.3390\/nu7064139","volume":"7","author":"F Dabrowski","year":"2015","unstructured":"Dabrowski F, Grzechocinska B, Wielgos M. The role of Vitamin D in Reproductive Health\u2014A trojan horse or the Golden Fleece? Nutrients. 2015;7(6):4139\u201353.","journal-title":"Nutrients"},{"issue":"1","key":"1578_CR42","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/s12958-019-0500-0","volume":"17","author":"X Liu","year":"2019","unstructured":"Liu X, et al. Effect of vitamin D status on normal fertilization rate following in vitro fertilization. Reproductive Biology Endocrinol. 2019;17(1):59.","journal-title":"Reproductive Biology Endocrinol"},{"issue":"1","key":"1578_CR43","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.ejogrb.2011.07.006","volume":"159","author":"A Aleyasin","year":"2011","unstructured":"Aleyasin A, et al. Predictive value of the level of vitamin D in follicular fluid on the outcome of assisted reproductive technology. Eur J Obstet Gynecol Reproductive Biology. 2011;159(1):132\u20137.","journal-title":"Eur J Obstet Gynecol Reproductive Biology"},{"issue":"4","key":"1578_CR44","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1016\/j.fertnstert.2009.05.019","volume":"94","author":"S Ozkan","year":"2010","unstructured":"Ozkan S, et al. Replete vitamin D stores predict reproductive success following in vitro fertilization. Fertil Steril. 2010;94(4):1314\u20139.","journal-title":"Fertil Steril"},{"issue":"1","key":"1578_CR45","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/1477-7827-8-91","volume":"8","author":"GM Anifandis","year":"2010","unstructured":"Anifandis GM, et al. Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome. Reproductive Biology Endocrinol. 2010;8(1):91.","journal-title":"Reproductive Biology Endocrinol"},{"key":"1578_CR46","doi-asserted-by":"crossref","unstructured":"Xu J et al. Vitamin D3 regulates follicular development and intrafollicular vitamin D biosynthesis and signaling in the primate ovary. Front Physiol.2018;9:1600.","DOI":"10.3389\/fphys.2018.01600"},{"key":"1578_CR47","doi-asserted-by":"crossref","unstructured":"Parikh G et al. Vitamin D regulates steroidogenesis and insulin-like growth factor binding protein-1 (IGFBP-1) production in human ovarian cells. Horm Metab Res. 2010;42(10):754\u20137.","DOI":"10.1055\/s-0030-1262837"},{"key":"1578_CR48","doi-asserted-by":"crossref","unstructured":"Varshney S et al. Disrupted placental vitamin D metabolism and calcium signaling in gestational diabetes and pre-eclampsia patients. Endocrine. 2023;80(1):191\u2013200.","DOI":"10.1007\/s12020-022-03272-9"},{"issue":"3","key":"1578_CR49","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1111\/jog.15521","volume":"49","author":"Z Yu","year":"2022","unstructured":"Yu Z, et al. Does vitamin D level associate with pregnancy outcomes in Chinese women undergoing in vitro fertilization\/intracytoplasmic sperm injection-embryo transfer? A retrospective cohort study. J Obstet Gynecol Res. 2022;49(3):835\u201345.","journal-title":"J Obstet Gynecol Res"},{"key":"1578_CR50","doi-asserted-by":"crossref","unstructured":"de Boer IH et al. Serum 25-hydroxyvitamin D concentration and risk for major clinical disease events in a community-based population of older adults: a cohort study. Ann Intern Med. 2012;156(9):627\u201334.","DOI":"10.7326\/0003-4819-156-9-201205010-00004"},{"key":"1578_CR51","doi-asserted-by":"crossref","unstructured":"Aune D et al. Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies. BMJ. 2011;343:d6617.","DOI":"10.1136\/bmj.d6617"},{"key":"1578_CR52","doi-asserted-by":"crossref","unstructured":"Xu C et al. Fat intake is not linked to prostate cancer: a systematic review and dose-response meta-analysis. PLoS ONE. 2015;10(7):e0131747.","DOI":"10.1371\/journal.pone.0131747"},{"key":"1578_CR53","doi-asserted-by":"crossref","unstructured":"Vale CL et al. Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data. Lancet. 2020;396(10260):1422\u20131431.","DOI":"10.1016\/S0140-6736(20)31952-8"},{"key":"1578_CR54","doi-asserted-by":"crossref","unstructured":"Hu Y et al. Vitamin D nutritional status and its related factors for Chinese children and adolescents in 2010\u20132012. Nutrients. 2017;9(9):1024.","DOI":"10.3390\/nu9091024"},{"key":"1578_CR55","doi-asserted-by":"crossref","unstructured":"Micha\u00eblsson K et al. The seasonal importance of serum 25-hydroxyvitamin D for bone mineral density in older women. J Intern Med. 2017;281(2):167\u2013178.","DOI":"10.1111\/joim.12563"},{"key":"1578_CR56","doi-asserted-by":"crossref","unstructured":"Yu HJ et al. Analysis of 25-hydroxyvitamin D status according to age, gender, and seasonal variation. J Clin Lab Anal. 2016;30(6):905\u2013911.","DOI":"10.1002\/jcla.21955"},{"key":"1578_CR57","doi-asserted-by":"crossref","unstructured":"O\u2019Neill CM et al. Seasonal changes in vitamin D-effective UVB availability in Europe and associations with population serum 25-hydroxyvitamin D. Nutrients. 2016;8(9):533.","DOI":"10.3390\/nu8090533"},{"key":"1578_CR58","doi-asserted-by":"crossref","unstructured":"Ingles SA. Can diet and\/or sunlight modify the relationship between vitamin D receptor polymorphisms and prostate cancer risk? Nutr Rev. 2007;65(8 Pt 2):S105\u20137.","DOI":"10.1301\/nr.2007.aug.S105-S107"},{"key":"1578_CR59","unstructured":"Ingles SA et al. Strength of linkage disequilibrium between two vitamin D receptor markers in five ethnic groups: implications for association studies. Cancer Epidemiol Biomarkers Prev. 1997;6(2):93\u20138."}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-024-01578-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-024-01578-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-024-01578-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T15:07:06Z","timestamp":1745939226000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-024-01578-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["1578"],"URL":"https:\/\/doi.org\/10.1007\/s43032-024-01578-9","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,22]]},"assertion":[{"value":"14 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all authors in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}