{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:28:45Z","timestamp":1744172925735,"version":"3.40.3"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104917"],"award-info":[{"award-number":["82104917"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2021MH079"],"award-info":[{"award-number":["ZR2021MH079"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1007\/s43032-025-01809-7","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T17:16:12Z","timestamp":1740762972000},"page":"1147-1154","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Role of Immune Cells in Mediating the Effect of Lipids on Preeclampsia"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8145-8774","authenticated-orcid":false,"given":"Chunxiao","family":"Dang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengfei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinxing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"issue":"5","key":"1809_CR1","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.jogc.2022.03.002","volume":"44","author":"LA Magee","year":"2022","unstructured":"Magee LA, Smith GN, Bloch C, C\u00f4t\u00e9 AM, Jain V, Nerenberg K, et al. Guideline no. 426: Hypertensive disorders of pregnancy: Diagnosis, prediction, prevention, and management. J Obstet Gynaecol Can. 2022;44(5):547-571.e1. https:\/\/doi.org\/10.1016\/j.jogc.2022.03.002.","journal-title":"J Obstet Gynaecol Can."},{"issue":"4","key":"1809_CR2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s11906-020-01039-z","volume":"22","author":"P Laissue","year":"2020","unstructured":"Laissue P, Vaiman D. Exploring the molecular aetiology of preeclampsia by massive parallel sequencing of DNA. Curr Hypertens Rep. 2020;22(4):31. https:\/\/doi.org\/10.1007\/s11906-020-01039-z.","journal-title":"Curr Hypertens Rep"},{"issue":"4","key":"1809_CR3","doi-asserted-by":"publisher","first-page":"795","DOI":"10.3390\/antiox12040795","volume":"12","author":"JT Stadler","year":"2023","unstructured":"Stadler JT, Scharnagl H, Wadsack C, Marsche G. Preeclampsia affects lipid metabolism and HDL function in mothers and their offspring. Antioxidants (Basel). 2023;12(4):795. https:\/\/doi.org\/10.3390\/antiox12040795.","journal-title":"Antioxidants (Basel)"},{"issue":"2","key":"1809_CR4","doi-asserted-by":"publisher","first-page":"2759","DOI":"10.1096\/fj.201801163R","volume":"33","author":"J Canfield","year":"2019","unstructured":"Canfield J, Arlier S, Mong EF, Lockhart J, VanWye J, Guzeloglu-Kayisli O, et al. Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration. FASEB J. 2019;33(2):2759\u201369. https:\/\/doi.org\/10.1096\/fj.201801163R.","journal-title":"FASEB J"},{"issue":"8","key":"1809_CR5","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s11906-017-0757-7","volume":"19","author":"LM Amaral","year":"2017","unstructured":"Amaral LM, Wallace K, Owens M, LaMarca B. Pathophysiology and current clinical management of preeclampsia. Curr Hypertens Rep. 2017;19(8):61. https:\/\/doi.org\/10.1007\/s11906-017-0757-7.","journal-title":"Curr Hypertens Rep"},{"issue":"10","key":"1809_CR6","doi-asserted-by":"publisher","first-page":"786","DOI":"10.2174\/1389201019666180925120109","volume":"19","author":"W Dymara-Konopka","year":"2018","unstructured":"Dymara-Konopka W, Laskowska M, Oleszczuk J. Preeclampsia - current management and future approach. Curr Pharm Biotechnol. 2018;19(10):786\u201396. https:\/\/doi.org\/10.2174\/1389201019666180925120109.","journal-title":"Curr Pharm Biotechnol"},{"key":"1809_CR7","doi-asserted-by":"publisher","first-page":"l2381","DOI":"10.1136\/bmj.l2381","volume":"366","author":"GJ Burton","year":"2019","unstructured":"Burton GJ, Redman CW, Roberts JM, Moffett A. Pre-eclampsia: pathophysiology and clinical implications. BMJ. 2019;366:l2381. https:\/\/doi.org\/10.1136\/bmj.l2381.","journal-title":"BMJ"},{"issue":"1","key":"1809_CR8","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1038\/s41598-018-37757-3","volume":"9","author":"SM Lee","year":"2019","unstructured":"Lee SM, Moon JY, Lim BY, Kim SM, Park CW, Kim BJ, et al. Increased biosynthesis and accumulation of cholesterol in maternal plasma, but not amniotic fluid in pre-eclampsia. Sci Rep. 2019;9(1):1550. https:\/\/doi.org\/10.1038\/s41598-018-37757-3.","journal-title":"Sci Rep"},{"key":"1809_CR9","doi-asserted-by":"publisher","first-page":"100118","DOI":"10.1016\/j.jlr.2021.100118","volume":"62","author":"B He","year":"2021","unstructured":"He B, Liu Y, Maurya MR, Benny P, Lassiter C, Li H, et al. The maternal blood lipidome is indicative of the pathogenesis of severe preeclampsia. J Lipid Res. 2021;62:100118. https:\/\/doi.org\/10.1016\/j.jlr.2021.100118.","journal-title":"J Lipid Res"},{"issue":"5","key":"1809_CR10","doi-asserted-by":"publisher","first-page":"482.e1","DOI":"10.1016\/j.ajog.2009.05.032","volume":"201","author":"A Wiznitzer","year":"2009","unstructured":"Wiznitzer A, Mayer A, Novack V, Sheiner E, Gilutz H, Malhotra A, et al. Association of lipid levels during gestation with preeclampsia and gestational diabetes mellitus: a population-based study. Am J Obstet Gynecol. 2009;201(5):482.e1-8. https:\/\/doi.org\/10.1016\/j.ajog.2009.05.032.","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"1809_CR11","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/s0002-9378(96)70336-8","volume":"174","author":"CA Hubel","year":"1996","unstructured":"Hubel CA, McLaughlin MK, Evans RW, Hauth BA, Sims CJ, Roberts JM. Fasting serum triglycerides, free fatty acids, and malondialdehyde are increased in preeclampsia, are positively correlated, and decrease within 48 hours post partum. Am J Obstet Gynecol. 1996;174(3):975\u201382. https:\/\/doi.org\/10.1016\/s0002-9378(96)70336-8.","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"1809_CR12","doi-asserted-by":"publisher","first-page":"2294691","DOI":"10.1080\/14767058.2023.2294691","volume":"37","author":"Y Wang","year":"2024","unstructured":"Wang Y, Liu S, Wu C, Yu H, Ji X. Association between circulating unsaturated fatty acid and preeclampsia: a two-sample Mendelian randomization study. J Matern Fetal Neonatal Med. 2024;37(1):2294691. https:\/\/doi.org\/10.1080\/14767058.2023.2294691.","journal-title":"J Matern Fetal Neonatal Med"},{"key":"1809_CR13","doi-asserted-by":"publisher","first-page":"115","DOI":"10.2147\/IJWH.S233029","volume":"12","author":"K Hessami","year":"2020","unstructured":"Hessami K, Kasraeian M, Asadi N, Vafaei H, Foroughinia L. Association of maternal and umbilical cord blood lipid parameters with uterine and fetal-placental blood flow in hypertensive and normotensive pregnancies. Int J Womens Health. 2020;12:115\u201325. https:\/\/doi.org\/10.2147\/IJWH.S233029.","journal-title":"Int J Womens Health"},{"issue":"1","key":"1809_CR14","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1080\/21655979.2021.1875707","volume":"12","author":"Y Meng","year":"2021","unstructured":"Meng Y, Li C, Liu CX. Immune cell infiltration landscape and immune marker molecular typing in preeclampsia. Bioengineered. 2021;12(1):540\u201354. https:\/\/doi.org\/10.1080\/21655979.2021.1875707.","journal-title":"Bioengineered"},{"issue":"1","key":"1809_CR15","doi-asserted-by":"publisher","first-page":"66.e1","DOI":"10.1016\/j.ajog.2013.09.010","volume":"210","author":"DB Nelson","year":"2014","unstructured":"Nelson DB, Ziadie MS, McIntire DD, Rogers BB, Leveno KJ. Placental pathology suggesting that preeclampsia is more than one disease. Am J Obstet Gynecol. 2014;210(1):66.e1-7. https:\/\/doi.org\/10.1016\/j.ajog.2013.09.010.","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"1809_CR16","doi-asserted-by":"publisher","first-page":"641.e1","DOI":"10.1016\/j.ajog.2022.07.021","volume":"227","author":"CE Dunk","year":"2022","unstructured":"Dunk CE, Bucher M, Zhang J, Hayder H, Geraghty DE, Lye SJ, et al. Human leukocyte antigen HLA-C, HLA-G, HLA-F, and HLA-E placental profiles are altered in early severe preeclampsia and preterm birth with chorioamnionitis. Am J Obstet Gynecol. 2022;227(4):641.e1-641.e13. https:\/\/doi.org\/10.1016\/j.ajog.2022.07.021.","journal-title":"Am J Obstet Gynecol"},{"issue":"12","key":"1809_CR17","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1016\/j.bbadis.2012.08.004","volume":"1822","author":"J Jebbink","year":"2012","unstructured":"Jebbink J, Wolters A, Fernando F, Afink G, van der Post J, Ris-Stalpers C. Molecular genetics of preeclampsia and HELLP syndrome - a review. Biochim Biophys Acta. 2012;1822(12):1960\u20139. https:\/\/doi.org\/10.1016\/j.bbadis.2012.08.004.","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"1809_CR18","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1161\/HYPERTENSIONAHA.113.02293","volume":"63","author":"S Rana","year":"2014","unstructured":"Rana S, Karumanchi SA, Lindheimer MD. Angiogenic factors in diagnosis, management, and research in preeclampsia. Hypertension. 2014;63(2):198\u2013202. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.113.02293.","journal-title":"Hypertension"},{"issue":"4","key":"1809_CR19","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1038\/s41581-022-00670-0","volume":"19","author":"E Deer","year":"2023","unstructured":"Deer E, Herrock O, Campbell N, Cornelius D, Fitzgerald S, Amaral LM, et al. The role of immune cells and mediators in preeclampsia. Nat Rev Nephrol. 2023;19(4):257\u201370. https:\/\/doi.org\/10.1038\/s41581-022-00670-0.","journal-title":"Nat Rev Nephrol"},{"key":"1809_CR20","doi-asserted-by":"publisher","first-page":"103812","DOI":"10.1016\/j.jri.2023.103812","volume":"156","author":"C Shen","year":"2023","unstructured":"Shen C, Song Y, Fan W, Guo X, Li J, Zhao R. Changes in expression levels of immune cells and inflammatory cytokines in pre-eclampsia patients before and after delivery. J Reprod Immunol. 2023;156:103812. https:\/\/doi.org\/10.1016\/j.jri.2023.103812.","journal-title":"J Reprod Immunol"},{"issue":"2","key":"1809_CR21","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/S2215-0366(19)30293-7","volume":"7","author":"R Carnegie","year":"2020","unstructured":"Carnegie R, Zheng J, Sallis HM, Jones HJ, Wade KH, Evans J, et al. Mendelian randomisation for nutritional psychiatry. Lancet Psychiatry. 2020;7(2):208\u201316. https:\/\/doi.org\/10.1016\/S2215-0366(19)30293-7.","journal-title":"Lancet Psychiatry"},{"issue":"5","key":"1809_CR22","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1093\/bioinformatics\/btz749","volume":"36","author":"J Zhao","year":"2020","unstructured":"Zhao J, Ming J, Hu X, Chen G, Liu J, Yang C. Bayesian weighted Mendelian randomization for causal inference based on summary statistics. Bioinformatics. 2020;36(5):1501\u20138. https:\/\/doi.org\/10.1093\/bioinformatics\/btz749.","journal-title":"Bioinformatics"},{"issue":"16","key":"1809_CR23","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1001\/jama.2021.18236","volume":"326","author":"VW Skrivankova","year":"2021","unstructured":"Skrivankova VW, Richmond RC, Woolf BAR, Yarmolinsky J, Davies NM, Swanson SA, et al. Strengthening the reporting of observational studies in epidemiology using mendelian randomization: The STROBE-MR statement. JAMA. 2021;326(16):1614\u201321. https:\/\/doi.org\/10.1001\/jama.2021.18236.","journal-title":"JAMA"},{"issue":"8","key":"1809_CR24","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1002\/sim.3034","volume":"27","author":"DA Lawlor","year":"2008","unstructured":"Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey SG. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med. 2008;27(8):1133\u201363. https:\/\/doi.org\/10.1002\/sim.3034.","journal-title":"Stat Med"},{"issue":"10","key":"1809_CR25","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1038\/s41588-021-00931-x","volume":"53","author":"S Sakaue","year":"2021","unstructured":"Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nat Genet. 2021;53(10):1415\u201324. https:\/\/doi.org\/10.1038\/s41588-021-00931-x.","journal-title":"Nat Genet"},{"issue":"1","key":"1809_CR26","doi-asserted-by":"publisher","first-page":"6934","DOI":"10.1038\/s41467-023-42532-8","volume":"14","author":"L Ottensmann","year":"2023","unstructured":"Ottensmann L, Tabassum R, Ruotsalainen SE, Gerl MJ, Klose C, Wid\u00e9n E, et al. Genome-wide association analysis of plasma lipidome identifies 495 genetic associations. Nat Commun. 2023;14(1):6934. https:\/\/doi.org\/10.1038\/s41467-023-42532-8.","journal-title":"Nat Commun"},{"issue":"11","key":"1809_CR27","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1038\/ng.3368","volume":"47","author":"C Sidore","year":"2015","unstructured":"Sidore C, Busonero F, Maschio A, Porcu E, Naitza S, Zoledziewska M, et al. Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers. Nat Genet. 2015;47(11):1272\u201381. https:\/\/doi.org\/10.1038\/ng.3368.","journal-title":"Nat Genet"},{"key":"1809_CR28","doi-asserted-by":"publisher","first-page":"1397670","DOI":"10.3389\/fendo.2024.1397670","volume":"15","author":"X Fang","year":"2024","unstructured":"Fang X, Deng Q, Yang H, Yan Z, Peng Z, Zhao Y, et al. Causal association of immune cells and endometriosis: a Mendelian randomization study. Front Endocrinol (Lausanne). 2024;15:1397670. https:\/\/doi.org\/10.3389\/fendo.2024.1397670.","journal-title":"Front Endocrinol (Lausanne)"},{"key":"1809_CR29","doi-asserted-by":"publisher","first-page":"1388920","DOI":"10.3389\/fneur.2024.1388920","volume":"15","author":"X Wang","year":"2024","unstructured":"Wang X, Xiong W, Li M, Wu L, Zhang Y, Zhu C, et al. Role of inflammatory cytokine in mediating the effect of plasma lipidome on epilepsy: a mediation Mendelian randomization study. Front Neurol. 2024;15:1388920. https:\/\/doi.org\/10.3389\/fneur.2024.1388920.","journal-title":"Front Neurol"},{"key":"1809_CR30","doi-asserted-by":"publisher","first-page":"e34408","DOI":"10.7554\/eLife.34408","volume":"7","author":"G Hemani","year":"2018","unstructured":"Hemani G, Zheng J, Elsworth B, Wade KH, Haberland V, Baird D, et al. The MR-Base platform supports systematic causal inference across the human phenome. Elife. 2018;7:e34408. https:\/\/doi.org\/10.7554\/eLife.34408.","journal-title":"Elife"},{"issue":"8","key":"1809_CR31","doi-asserted-by":"publisher","first-page":"e3249","DOI":"10.1210\/clinem\/dgab097","volume":"106","author":"Z Zhuang","year":"2021","unstructured":"Zhuang Z, Yu C, Guo Y, Bian Z, Yang L, Millwood IY, et al. Metabolic signatures of genetically elevated vitamin D among Chinese: Observational and Mendelian randomization study. J Clin Endocrinol Metab. 2021;106(8):e3249\u201360. https:\/\/doi.org\/10.1210\/clinem\/dgab097.","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"1809_CR32","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1186\/s12916-020-01778-5","volume":"18","author":"F Wu","year":"2020","unstructured":"Wu F, Huang Y, Hu J, Shao Z. Mendelian randomization study of inflammatory bowel disease and bone mineral density. BMC Med. 2020;18(1):312. https:\/\/doi.org\/10.1186\/s12916-020-01778-5.","journal-title":"BMC Med"},{"issue":"3\u20134","key":"1809_CR33","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1002\/gepi.22445","volume":"46","author":"A Wang","year":"2022","unstructured":"Wang A, Liu W, Liu Z. A two-sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID-19 outcomes. Genet Epidemiol. 2022;46(3\u20134):159\u201369. https:\/\/doi.org\/10.1002\/gepi.22445.","journal-title":"Genet Epidemiol"},{"issue":"8","key":"1809_CR34","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1038\/s41588-018-0164-2","volume":"50","author":"M Verbanck","year":"2018","unstructured":"Verbanck M, Chen CY, Neale B, Do R. Publisher Correction: Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018;50(8):1196. https:\/\/doi.org\/10.1038\/s41588-018-0164-2.","journal-title":"Nat Genet"},{"issue":"5","key":"1809_CR35","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10654-021-00757-1","volume":"36","author":"AR Carter","year":"2021","unstructured":"Carter AR, Sanderson E, Hammerton G, Richmond RC, Davey Smith G, Heron J, et al. Mendelian randomisation for mediation analysis: current methods and challenges for implementation. Eur J Epidemiol. 2021;36(5):465\u201378. https:\/\/doi.org\/10.1007\/s10654-021-00757-1.","journal-title":"Eur J Epidemiol"},{"issue":"10","key":"1809_CR36","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1111\/j.1447-0756.2011.01562.x","volume":"37","author":"O Demirci","year":"2011","unstructured":"Demirci O, Tu\u011frul AS, Dolgun N, S\u00f6zen H, Eren S. Serum lipids level assessed in early pregnancy and risk of pre-eclampsia. J Obstet Gynaecol Res. 2011;37(10):1427\u201332. https:\/\/doi.org\/10.1111\/j.1447-0756.2011.01562.x.","journal-title":"J Obstet Gynaecol Res"},{"issue":"3","key":"1809_CR37","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1055\/s-2005-872438","volume":"31","author":"K Omatsu","year":"2005","unstructured":"Omatsu K, Kobayashi T, Murakami Y, Suzuki M, Ohashi R, Sugimura M, et al. Phosphatidylserine\/phosphatidylcholine microvesicles can induce preeclampsia-like changes in pregnant mice. Semin Thromb Hemost. 2005;31(3):314\u201320. https:\/\/doi.org\/10.1055\/s-2005-872438.","journal-title":"Semin Thromb Hemost"},{"issue":"2","key":"1809_CR38","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/s0006-2952(02)01179-6","volume":"64","author":"JH Kabarowski","year":"2002","unstructured":"Kabarowski JH, Xu Y, Witte ON. Lysophosphatidylcholine as a ligand for immunoregulation. Biochem Pharmacol. 2002;64(2):161\u20137. https:\/\/doi.org\/10.1016\/s0006-2952(02)01179-6.","journal-title":"Biochem Pharmacol"},{"key":"1809_CR39","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3389\/fncel.2019.00002","volume":"13","author":"E Tanguy","year":"2019","unstructured":"Tanguy E, Wang Q, Moine H, Vitale N. Phosphatidic acid: From pleiotropic functions to neuronal pathology. Front Cell Neurosci. 2019;13:2. https:\/\/doi.org\/10.3389\/fncel.2019.00002.","journal-title":"Front Cell Neurosci"},{"issue":"8","key":"1809_CR40","doi-asserted-by":"publisher","first-page":"2970","DOI":"10.3390\/jcm12082970","volume":"12","author":"IM Williams","year":"2023","unstructured":"Williams IM, Albertolle ME, Layden AJ, Tao SY, Fisher SJ, Gandley RE, et al. Lipidomics reveals elevated plasmalogens in women with obesity who develop preeclampsia. J Clin Med. 2023;12(8):2970. https:\/\/doi.org\/10.3390\/jcm12082970.","journal-title":"J Clin Med"},{"issue":"24","key":"1809_CR41","doi-asserted-by":"publisher","first-page":"00782","DOI":"10.3168\/jds.2023-24357","volume":"S0022\u20130302","author":"X Sun","year":"2024","unstructured":"Sun X, Gao S, Chang R, Jia H, Xu Q, Mauck J, et al. Fatty acids promote M1 polarization of monocyte-derived macrophages in healthy or ketotic dairy cows and a bovine macrophage cell line via impairing mTOR-mediated autophagy. J Dairy Sci. 2024;S0022\u20130302(24):00782\u20133. https:\/\/doi.org\/10.3168\/jds.2023-24357.","journal-title":"J Dairy Sci"},{"key":"1809_CR42","doi-asserted-by":"publisher","first-page":"104704","DOI":"10.1016\/j.ebiom.2023.104704","volume":"94","author":"LA Bartho","year":"2023","unstructured":"Bartho LA, Keenan E, Walker SP, MacDonald TM, Nijagal B, Tong S, et al. Plasma lipids are dysregulated preceding diagnosis of preeclampsia or delivery of a growth restricted infant. EBioMedicine. 2023;94:104704. https:\/\/doi.org\/10.1016\/j.ebiom.2023.104704.","journal-title":"EBioMedicine"},{"issue":"Suppl 1","key":"1809_CR43","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.24875\/GMM.M19000284","volume":"155","author":"M\u00c1 Serrano-Berrones","year":"2019","unstructured":"Serrano-Berrones M\u00c1, Barrag\u00e1n-Padilla SB. Study on the association of hypertriglyceridemia with hypertensive states of pregnancy. Gac Med Mex. 2019;155(Suppl 1):S17\u201321. https:\/\/doi.org\/10.24875\/GMM.M19000284.","journal-title":"Gac Med Mex"},{"issue":"2","key":"1809_CR44","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1515\/hmbci-2015-0025","volume":"26","author":"E Herrera","year":"2016","unstructured":"Herrera E, Desoye G. Maternal and fetal lipid metabolism under normal and gestational diabetic conditions. Horm Mol Biol Clin Investig. 2016;26(2):109\u201327. https:\/\/doi.org\/10.1515\/hmbci-2015-0025.","journal-title":"Horm Mol Biol Clin Investig"},{"issue":"1","key":"1809_CR45","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1002\/JLB.5RU1120-787RR","volume":"111","author":"D Miller","year":"2022","unstructured":"Miller D, Motomura K, Galaz J, Gershater M, Lee ED, Romero R, et al. Cellular immune responses in the pathophysiology of preeclampsia. J Leukoc Biol. 2022;111(1):237\u201360. https:\/\/doi.org\/10.1002\/JLB.5RU1120-787RR.","journal-title":"J Leukoc Biol"},{"key":"1809_CR46","first-page":"24","volume":"201","author":"ML Tortladze","year":"2011","unstructured":"Tortladze ML, Kintraia NP, Sanikidze TV. Some considerations of immune metabolism at preeclampsia. Georgian Med News. 2011;201:24\u20137 Russian.","journal-title":"Georgian Med News."},{"issue":"1","key":"1809_CR47","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1186\/s12888-023-05081-4","volume":"23","author":"C Wang","year":"2023","unstructured":"Wang C, Zhu D, Zhang D, Zuo X, Yao L, Liu T, et al. Causal role of immune cells in schizophrenia: Mendelian randomization (MR) study. BMC Psychiatry. 2023;23(1):590. https:\/\/doi.org\/10.1186\/s12888-023-05081-4.","journal-title":"BMC Psychiatry"},{"key":"1809_CR48","doi-asserted-by":"publisher","first-page":"1095879","DOI":"10.3389\/fimmu.2022.1095879","volume":"13","author":"MH Mercnik","year":"2023","unstructured":"Mercnik MH, Schliefsteiner C, Fluhr H, Wadsack C. Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia. Front Immunol. 2023;13:1095879. https:\/\/doi.org\/10.3389\/fimmu.2022.1095879.","journal-title":"Front Immunol"},{"issue":"7","key":"1809_CR49","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s10654-015-0011-z","volume":"30","author":"S Burgess","year":"2015","unstructured":"Burgess S, Scott RA, Timpson NJ, Davey Smith G, Thompson SG, EPIC- InterAct Consortium. Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors. Eur J Epidemiol. 2015;30(7):543\u201352. https:\/\/doi.org\/10.1007\/s10654-015-0011-z.","journal-title":"Eur J Epidemiol"}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-025-01809-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-025-01809-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-025-01809-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T21:51:30Z","timestamp":1744149090000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-025-01809-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,28]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["1809"],"URL":"https:\/\/doi.org\/10.1007\/s43032-025-01809-7","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"type":"print","value":"1933-7191"},{"type":"electronic","value":"1933-7205"}],"subject":[],"published":{"date-parts":[[2025,2,28]]},"assertion":[{"value":"21 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Mendelian randomization analysis was performed using pooled data obtained from GWAS. These data were collected in compliance with the principle of written informed consent and ethical approval was obtained.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no conflict of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}}]}}