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Serum P levels on the day of embryo transfer did not differ significantly between patients who achieved CP and those who did not (12.76\u2009\u00b1\u20094.1\u00a0ng\/mL vs. 11.9\u2009\u00b1\u20095.6\u00a0ng\/mL;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.3318). The optimal serum P cutoff level associated with higher CP rates was 10.6\u00a0ng\/mL, with a sensitivity of 72%, a specificity of 44%, and an AUC of 0.58, indicating poor predictive value. However, patients with serum P levels above this cutoff had a significantly higher CP rate than those with lower values (25.9% vs. 14.6%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0372). In the multivariate logistic regression model, this difference was not statistically significant (OR\u2009=\u20092; 95% CI: 0.9\u20135). Routine monitoring of serum P levels on the day of embryo transfer in AEP cycles using vaginal micronized P is not justified, as serum P levels do not effectively predict CP outcomes in cycles using autologous oocytes.\n                  <\/jats:p>","DOI":"10.1007\/s43032-026-02157-w","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T19:01:09Z","timestamp":1784746869000},"page":"1577-1588","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Progesterone Levels on the Day of Frozen-thawed Embryo Transfer in Artificial Cycles with Vaginal Progesterone Do not Predict Clinical Pregnancy: a Prospective Study"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1230-4522","authenticated-orcid":false,"given":"Suelen Maria Parizotto","family":"Furlan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6218-7873","authenticated-orcid":false,"given":"Carla Maria Franco","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9308-8344","authenticated-orcid":false,"given":"Rui Alberto","family":"Ferriani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2368-4188","authenticated-orcid":false,"given":"Paula Andrea","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"2157_CR1","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/s00404-022-06674-2","volume":"308","author":"A Almohammadi","year":"2023","unstructured":"Almohammadi A, Raveendran A, Black M, Maheshwari A. 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PAN and RAF: Conceptualization- Methodology- Supervision- Writing- Reviewing and Editing.","order":5,"name":"Ethics","label":"Authors\u2019 Roles","group":{"name":"EthicsHeading","label":"Declarations"}}]}}