{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:35:52Z","timestamp":1787322952924,"version":"build-2736575974"},"reference-count":111,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"DOI":"10.1007\/s43032-026-02175-8","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:35:25Z","timestamp":1787319325000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Potential and Challenges of Menstrual Blood-derived Mesenchymal Stem Cells\/Stromal Cells in Treating Female Infertility: A Recent Review"],"prefix":"10.1007","author":[{"given":"Min","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinqiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8517-7603","authenticated-orcid":false,"given":"Yuehui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2175_CR1","doi-asserted-by":"publisher","first-page":"2497","DOI":"10.1016\/s0140-6736(20)32708-2","volume":"397","author":"J Qiao","year":"2021","unstructured":"Qiao J, Wang Y, Li X, Jiang F, Zhang Y, Ma J, et al. A Lancet Commission on 70 years of women\u2019s reproductive, maternal, newborn, child, and adolescent health in China. Lancet. 2021;397:2497\u2013536. https:\/\/doi.org\/10.1016\/s0140-6736(20)32708-2","journal-title":"Lancet"},{"key":"2175_CR2","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1001\/jama.2021.4788","volume":"326","author":"SA Carson","year":"2021","unstructured":"Carson SA, Kallen AN. Diagnosis and management of infertility: a review. JAMA. 2021;326:65\u201376. https:\/\/doi.org\/10.1001\/jama.2021.4788.","journal-title":"JAMA"},{"key":"2175_CR3","doi-asserted-by":"publisher","first-page":"591837","DOI":"10.3389\/fendo.2020.591837","volume":"11","author":"A Garolla","year":"2020","unstructured":"Garolla A, Pizzol D, Carosso AR, Borini A, Ubaldi FM, Calogero AE, et al. Practical clinical and diagnostic pathway for the investigation of the infertile couple. Front Endocrinol. 2020;11:591837. https:\/\/doi.org\/10.3389\/fendo.2020.591837.","journal-title":"Front Endocrinol"},{"key":"2175_CR4","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/1479-5876-5-57","volume":"5","author":"X Meng","year":"2007","unstructured":"Meng X, Ichim TE, Zhong J, Rogers A, Yin Z, Jackson J, et al. Endometrial regenerative cells: a novel stem cell population. J Transl Med. 2007;5:57. https:\/\/doi.org\/10.1186\/1479-5876-5-57","journal-title":"J translational Med"},{"key":"2175_CR5","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1089\/scd.2013.0390","volume":"23","author":"X Wu","year":"2014","unstructured":"Wu X, Luo Y, Chen J, Pan R, Xiang B, Du X, et al. Transplantation of human menstrual blood progenitor cells improves hyperglycemia by promoting endogenous progenitor differentiation in type 1 diabetic mice. Stem Cells Dev. 2014;23:1245\u201357. https:\/\/doi.org\/10.1089\/scd.2013.0390.","journal-title":"Stem Cells Dev"},{"key":"2175_CR6","doi-asserted-by":"publisher","first-page":"303","DOI":"10.3727\/096368908784153922","volume":"17","author":"AN Patel","year":"2008","unstructured":"Patel AN, Park E, Kuzman M, Benetti F, Silva FJ, Allickson JG. Multipotent menstrual blood stromal stem cells: isolation, characterization, and differentiation. Cell Transplant. 2008;17:303\u201311. https:\/\/doi.org\/10.3727\/096368908784153922.","journal-title":"Cell Transplant"},{"key":"2175_CR7","doi-asserted-by":"publisher","first-page":"3615729","DOI":"10.1155\/2017\/3615729","volume":"2017","author":"R Moreno","year":"2017","unstructured":"Moreno R, Rojas LA, Villellas FV, Soriano VC, Garc\u00eda-Castro J, Fajardo CA, et al. Human menstrual blood-derived mesenchymal stem cells as potential cell carriers for oncolytic adenovirus. Stem Cells Int. 2017;2017:3615729. https:\/\/doi.org\/10.1155\/2017\/3615729.","journal-title":"Stem cells Int"},{"key":"2175_CR8","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1186\/s12967-015-0516-y","volume":"13","author":"D Lai","year":"2015","unstructured":"Lai D, Wang F, Yao X, Zhang Q, Wu X, Xiang C. Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure. J Transl Med. 2015;13:155. https:\/\/doi.org\/10.1186\/s12967-015-0516-y","journal-title":"J translational Med"},{"key":"2175_CR9","doi-asserted-by":"publisher","first-page":"205","DOI":"10.3389\/fimmu.2014.00205","volume":"5","author":"M Khoury","year":"2014","unstructured":"Khoury M, Alcayaga-Miranda F, Illanes SE, Figueroa FE. The promising potential of menstrual stem cells for antenatal diagnosis and cell therapy. Front Immunol. 2014;5:205. https:\/\/doi.org\/10.3389\/fimmu.2014.00205.","journal-title":"Front Immunol"},{"key":"2175_CR10","doi-asserted-by":"publisher","first-page":"2201","DOI":"10.3892\/ijmm.2018.3415","volume":"41","author":"SX Zheng","year":"2018","unstructured":"Zheng SX, Wang J, Wang XL, Ali A, Wu LM, Liu YS. Feasibility analysis of treating severe intrauterine adhesions by transplanting menstrual blood-derived stem cells. Int J Mol Med. 2018;41:2201\u201312. https:\/\/doi.org\/10.3892\/ijmm.2018.3415.","journal-title":"Int J Mol Med"},{"key":"2175_CR11","doi-asserted-by":"publisher","first-page":"497","DOI":"10.3389\/fcell.2020.00497","volume":"8","author":"M Bozorgmehr","year":"2020","unstructured":"Bozorgmehr M, Gurung S, Darzi S, Nikoo S, Kazemnejad S, Zarnani AH, et al. Endometrial and menstrual blood mesenchymal stem\/stromal cells: biological properties and clinical application. Front Cell Dev Biol. 2020;8:497. https:\/\/doi.org\/10.3389\/fcell.2020.00497","journal-title":"Front cell Dev biology"},{"key":"2175_CR12","doi-asserted-by":"publisher","first-page":"103501","DOI":"10.1016\/j.isci.2021.103501","volume":"24","author":"A Sanchez-Mata","year":"2021","unstructured":"Sanchez-Mata A, Gonzalez-Mu\u00f1oz E. Understanding menstrual blood-derived stromal\/stem cells: Definition and properties. Are we rushing into their therapeutic applications? iScience. 2021;24:103501. https:\/\/doi.org\/10.1016\/j.isci.2021.103501","journal-title":"iScience"},{"key":"2175_CR13","doi-asserted-by":"publisher","first-page":"4","DOI":"10.2174\/1876893801103010004","volume":"3","author":"JG Allickson","year":"2011","unstructured":"Allickson JG, Sanchez A, Yefimenko N, Borlongan CV, Sanberg PR. Recent studies assessing the proliferative capability of a novel adult stem cell identified in menstrual blood. Open Stem Cell J. 2011;3:4\u201310. https:\/\/doi.org\/10.2174\/1876893801103010004","journal-title":"open stem cell J"},{"key":"2175_CR14","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1111\/jcmm.13437","volume":"22","author":"Y Liu","year":"2018","unstructured":"Liu Y, Niu R, Yang F, Yan Y, Liang S, Sun Y, et al. Biological characteristics of human menstrual blood-derived endometrial stem cells. J Cell Mol Med. 2018;22:1627\u201339. https:\/\/doi.org\/10.1111\/jcmm.13437.","journal-title":"J Cell Mol Med"},{"key":"2175_CR15","doi-asserted-by":"publisher","first-page":"D1670","DOI":"10.1093\/nar\/gkae973","volume":"53","author":"S Jiang","year":"2025","unstructured":"Jiang S, Li H, Zhang L, Mu W, Zhang Y, Chen T, et al. Generic Diagramming Platform (GDP): a comprehensive database of high-quality biomedical graphics. Nucleic Acids Res. 2025;53:D1670\u201376. https:\/\/doi.org\/10.1093\/nar\/gkae973.","journal-title":"Nucleic Acids Res"},{"key":"2175_CR16","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1080\/09513590.2019.1579788","volume":"35","author":"LR Fiorelli-Arazawa","year":"2019","unstructured":"Fiorelli-Arazawa LR, Haddad JM, Nicola MH, Machado J, Coimbra AC, Santamaria X, et al. Hormonal oral contraceptive influence on isolation, characterization and cryopreservation of mesenchymal stem cells from menstrual fluid. Gynecol Endocrinol. 2019;35:638\u201344. https:\/\/doi.org\/10.1080\/09513590.2019.1579788","journal-title":"Gynecol endocrinology: official J Int Soc Gynecol Endocrinol"},{"key":"2175_CR17","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1186\/s13287-023-03524-z","volume":"14","author":"S Hosoya","year":"2023","unstructured":"Hosoya S, Yokomizo R, Kishigami H, Fujiki Y, Kaneko E, Amita M, et al. Novel therapeutic strategies for injured endometrium: intrauterine transplantation of menstrual blood\u2013derived cells from infertile patients. Stem Cell Res Ther. 2023;14:297. https:\/\/doi.org\/10.1186\/s13287-023-03524-z.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR18","first-page":"14584","volume":"8","author":"J Chen","year":"2015","unstructured":"Chen J, Du X, Chen Q, Xiang C. Effects of donors\u2019 age and passage number on the biological characteristics of menstrual blood-derived stem cells. Int J Clin Exp Pathol. 2015;8:14584\u201395.","journal-title":"Int J Clin Exp Pathol"},{"key":"2175_CR19","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.apjtm.2015.07.022","volume":"8","author":"JY Chen","year":"2015","unstructured":"Chen JY, Mou XZ, Du XC, Xiang C. Comparative analysis of biological characteristics of adult mesenchymal stem cells with different tissue origins. Asian Pac J Trop Med. 2015;8:739\u201346. https:\/\/doi.org\/10.1016\/j.apjtm.2015.07.022.","journal-title":"Asian Pac J Trop Med"},{"key":"2175_CR20","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1091\/mbc.e06-09-0872","volume":"18","author":"CH Cui","year":"2007","unstructured":"Cui CH, Uyama T, Miyado K, Terai M, Kyo S, Kiyono T, et al. Menstrual blood-derived cells confer human dystrophin expression in the murine model of Duchenne muscular dystrophy via cell fusion and myogenic transdifferentiation. Mol Biol Cell. 2007;18:1586\u201394. https:\/\/doi.org\/10.1091\/mbc.e06-09-0872.","journal-title":"Mol Biol Cell"},{"key":"2175_CR21","doi-asserted-by":"publisher","first-page":"e86075","DOI":"10.1371\/journal.pone.0086075","volume":"9","author":"S Khanjani","year":"2014","unstructured":"Khanjani S, Khanmohammadi M, Zarnani AH, Akhondi MM, Ahani A, Ghaempanah Z, et al. Comparative evaluation of differentiation potential of menstrual blood- versus bone marrow-derived stem cells into hepatocyte-like cells. PLoS ONE. 2014;9:e86075. https:\/\/doi.org\/10.1371\/journal.pone.0086075.","journal-title":"PLoS ONE"},{"key":"2175_CR22","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1093\/molehr\/gau044","volume":"20","author":"S Nikoo","year":"2014","unstructured":"Nikoo S, Ebtekar M, Jeddi-Tehrani M, Shervin A, Bozorgmehr M, Vafaei S, et al. Menstrual blood-derived stromal stem cells from women with and without endometriosis reveal different phenotypic and functional characteristics. Mol Hum Reprod. 2014;20:905\u201318. https:\/\/doi.org\/10.1093\/molehr\/gau044.","journal-title":"Mol Hum Reprod"},{"key":"2175_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13287-018-1105-9","volume":"10","author":"L Chen","year":"2019","unstructured":"Chen L, Qu J, Xiang C. The multi-functional roles of menstrual blood-derived stem cells in regenerative medicine. Stem Cell Res Ther. 2019;10:1. https:\/\/doi.org\/10.1186\/s13287-018-1105-9.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR24","doi-asserted-by":"publisher","unstructured":"de Oliveira RZ, de Oliveira Buono F, Cressoni ACL, Penariol LBC, Padovan CC, Tozetti PA, et al. Overexpression of miR-200b-3p in menstrual blood-derived mesenchymal stem cells from endometriosis women. Reprod Sci (Thousand Oaks, Calif.). 2022;29:734\u201342. https:\/\/doi.org\/10.1007\/s43032-022-00860-y","DOI":"10.1007\/s43032-022-00860-y"},{"key":"2175_CR25","doi-asserted-by":"publisher","first-page":"3615","DOI":"10.1016\/j.ygeno.2020.04.022","volume":"112","author":"S Sharma","year":"2020","unstructured":"Sharma S, Bhonde R. Genetic and epigenetic stability of stem cells: Epigenetic modifiers modulate the fate of mesenchymal stem cells. Genomics. 2020;112:3615\u201323. https:\/\/doi.org\/10.1016\/j.ygeno.2020.04.022.","journal-title":"Genomics"},{"key":"2175_CR26","doi-asserted-by":"publisher","first-page":"765265","DOI":"10.3389\/fcell.2021.765265","volume":"9","author":"E Valatkait\u0117","year":"2021","unstructured":"Valatkait\u0117 E, Bau\u0161yt\u0117 R, Vitkevi\u010dien\u0117 A, Rama\u0161auskait\u0117 D, Navakauskien\u0117 R. Decidualization potency and epigenetic changes in human endometrial origin stem cells during propagation. Front Cell Dev Biol. 2021;9:765265. https:\/\/doi.org\/10.3389\/fcell.2021.765265","journal-title":"Front cell Dev biology"},{"key":"2175_CR27","doi-asserted-by":"publisher","first-page":"368","DOI":"10.4252\/wjsc.v12.i5.368","volume":"12","author":"QY Chang","year":"2020","unstructured":"Chang QY, Zhang SW, Li PP, Yuan ZW, Tan JC. Safety of menstrual blood-derived stromal cell transplantation in treatment of intrauterine adhesion. World J Stem Cells. 2020;12:368\u201380. https:\/\/doi.org\/10.4252\/wjsc.v12.i5.368","journal-title":"World J stem cells"},{"key":"2175_CR28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1479-5876-7-15","volume":"7","author":"Z Zhong","year":"2009","unstructured":"Zhong Z, Patel AN, Ichim TE, Riordan NH, Wang H, Min WP, et al. Feasibility investigation of allogeneic endometrial regenerative cells. J Transl Med. 2009;7:15. https:\/\/doi.org\/10.1186\/1479-5876-7-15","journal-title":"J translational Med"},{"key":"2175_CR29","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1186\/s13287-019-1503-7","volume":"10","author":"L Chen","year":"2019","unstructured":"Chen L, Qu J, Cheng T, Chen X, Xiang C. Menstrual blood-derived stem cells: toward therapeutic mechanisms, novel strategies, and future perspectives in the treatment of diseases. Stem Cell Res Ther. 2019;10:406. https:\/\/doi.org\/10.1186\/s13287-019-1503-7.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR30","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13287-016-0453-6","volume":"8","author":"L Chen","year":"2017","unstructured":"Chen L, Xiang B, Wang X, Xiang C. Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure. Stem Cell Res Ther. 2017;8:9. https:\/\/doi.org\/10.1186\/s13287-016-0453-6.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR31","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1089\/scd.2009.0340","volume":"19","author":"CV Borlongan","year":"2010","unstructured":"Borlongan CV, Kaneko Y, Maki M, Yu SJ, Ali M, Allickson JG, et al. Menstrual blood cells display stem cell-like phenotypic markers and exert neuroprotection following transplantation in experimental stroke. Stem Cells Dev. 2010;19:439\u201352. https:\/\/doi.org\/10.1089\/scd.2009.0340.","journal-title":"Stem Cells Dev"},{"key":"2175_CR32","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1634\/stemcells.2007-0826","volume":"26","author":"N Hida","year":"2008","unstructured":"Hida N, Nishiyama N, Miyoshi S, Kira S, Segawa K, Uyama T, et al. Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells. Stem Cells. 2008;26:1695\u2013704. https:\/\/doi.org\/10.1634\/stemcells.2007-0826.","journal-title":"Stem Cells"},{"key":"2175_CR33","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1111\/jcmm.12100","volume":"17","author":"Z Jiang","year":"2013","unstructured":"Jiang Z, Hu X, Yu H, Xu Y, Wang L, Chen H, et al. Human endometrial stem cells confer enhanced myocardial salvage and regeneration by paracrine mechanisms. J Cell Mol Med. 2013;17:1247\u201360. https:\/\/doi.org\/10.1111\/jcmm.12100.","journal-title":"J Cell Mol Med"},{"key":"2175_CR34","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1016\/j.ijcard.2013.03.126","volume":"168","author":"Z Zhang","year":"2013","unstructured":"Zhang Z, Wang JA, Xu Y, Jiang Z, Wu R, Wang L, et al. Menstrual blood derived mesenchymal cells ameliorate cardiac fibrosis via inhibition of endothelial to mesenchymal transition in myocardial infarction. Int J Cardiol. 2013;168:1711\u20134. https:\/\/doi.org\/10.1016\/j.ijcard.2013.03.126.","journal-title":"Int J Cardiol"},{"key":"2175_CR35","doi-asserted-by":"publisher","first-page":"209","DOI":"10.5966\/sctm.2015-0386","volume":"6","author":"K Wang","year":"2017","unstructured":"Wang K, Jiang Z, Webster KA, Chen J, Hu H, Zhou Y, et al. Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal MicroRNA-21. Stem Cells Transl Med. 2017;6:209\u201322. https:\/\/doi.org\/10.5966\/sctm.2015-0386","journal-title":"Stem cells translational Med"},{"key":"2175_CR36","doi-asserted-by":"publisher","first-page":"140","DOI":"10.3389\/fnmol.2018.00140","volume":"11","author":"Y Zhao","year":"2018","unstructured":"Zhao Y, Chen X, Wu Y, Wang Y, Li Y, Xiang C. Transplantation of human menstrual blood-derived mesenchymal stem cells alleviates Alzheimer\u2019s disease-like pathology in APP\/PS1 transgenic mice. Front Mol Neurosci. 2018;11:140. https:\/\/doi.org\/10.3389\/fnmol.2018.00140.","journal-title":"Front Mol Neurosci"},{"key":"2175_CR37","doi-asserted-by":"publisher","unstructured":"Xiang B, Chen L, Wang X, Zhao Y, Wang Y, Xiang C. Transplantation of menstrual blood-derived mesenchymal stem cells promotes the repair of LPS-induced acute lung injury. Int J Mol Sci. 2017;18. https:\/\/doi.org\/10.3390\/ijms18040689.","DOI":"10.3390\/ijms18040689"},{"key":"2175_CR38","doi-asserted-by":"publisher","first-page":"464","DOI":"10.3389\/fphys.2018.00464","volume":"9","author":"J Cuenca","year":"2018","unstructured":"Cuenca J, Le-Gatt A, Castillo V, Belletti J, D\u00edaz M, Kurte GM, et al. The reparative abilities of menstrual stem cells modulate the wound matrix signals and improve cutaneous regeneration. Front Physiol. 2018;9:464. https:\/\/doi.org\/10.3389\/fphys.2018.00464.","journal-title":"Front Physiol"},{"key":"2175_CR39","doi-asserted-by":"publisher","first-page":"2447","DOI":"10.1210\/clinem\/dgad463","volume":"108","author":"HJ Teede","year":"2023","unstructured":"Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, et al. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. J Clin Endocrinol Metab. 2023;108:2447\u201369. https:\/\/doi.org\/10.1210\/clinem\/dgad463","journal-title":"J Clin Endocrinol Metab"},{"key":"2175_CR40","unstructured":"Li W. Effect of CYP19A1 in rat ovary with polycystic ovary syndrome by human menstrual blood-derived mesenchymal stem cells. Master\u2019s thesis, Qingdao University; 2020."},{"key":"2175_CR41","doi-asserted-by":"publisher","first-page":"10365","DOI":"10.1002\/jcb.27380","volume":"119","author":"H Jafarzadeh","year":"2018","unstructured":"Jafarzadeh H, Nazarian H, Ghaffari Novin M, Shams Mofarahe Z, Eini F, Piryaei A. Improvement of oocyte in vitro maturation from mice with polycystic ovary syndrome by human mesenchymal stromal cell-conditioned media. J Cell Biochem. 2018;119:10365\u201375. https:\/\/doi.org\/10.1002\/jcb.27380.","journal-title":"J Cell Biochem"},{"key":"2175_CR42","doi-asserted-by":"publisher","first-page":"291","DOI":"10.2174\/011574888x298902240523103352","volume":"20","author":"H Rastegari","year":"2025","unstructured":"Rastegari H, Kazemnejad S, Hayati Roodbari N, Ansaripour S. Role of menstrual blood stem cell-derived secretome, follicular fluid, and melatonin in oocyte maturation and embryo development in polycystic ovary syndrome. Curr Stem Cell Res Ther. 2025;20:291\u2013301. https:\/\/doi.org\/10.2174\/011574888x298902240523103352","journal-title":"Curr Stem Cell Res Therapy"},{"key":"2175_CR43","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.biopha.2018.03.056","volume":"102","author":"G Sheikhansari","year":"2018","unstructured":"Sheikhansari G, Aghebati-Maleki L, Nouri M, Jadidi-Niaragh F, Yousefi M. Current approaches for the treatment of premature ovarian failure with stem cell therapy. Biomed Pharmacother. 2018;102:254\u201362. https:\/\/doi.org\/10.1016\/j.biopha.2018.03.056","journal-title":"Biomed pharmacotherapy = Biomedecine pharmacotherapie"},{"key":"2175_CR44","doi-asserted-by":"publisher","first-page":"2169","DOI":"10.1200\/jco.2017.76.3441","volume":"36","author":"W van Dorp","year":"2018","unstructured":"van Dorp W, Haupt R, Anderson RA, Mulder RL, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, et al. Reproductive function and outcomes in female survivors of childhood, adolescent, and young adult cancer: a review. J Clin Oncol. 2018;36:2169\u201380. https:\/\/doi.org\/10.1200\/jco.2017.76.3441","journal-title":"J Clin oncology: official J Am Soc Clin Oncol"},{"key":"2175_CR45","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1089\/cell.2019.0020","volume":"21","author":"P Noory","year":"2019","unstructured":"Noory P, Navid S, Zanganeh BM, Talebi A, Borhani-Haghighi M, Gholami K, et al. Human menstrual blood stem cell-derived granulosa cells participate in ovarian follicle formation in a rat model of premature ovarian failure in vivo. Cell Reprogram. 2019;21:249\u201359. https:\/\/doi.org\/10.1089\/cell.2019.0020","journal-title":"Cell reprogramming"},{"key":"2175_CR46","doi-asserted-by":"publisher","first-page":"3826","DOI":"10.18632\/aging.204043","volume":"14","author":"Q Zhang","year":"2022","unstructured":"Zhang Q, Liu C, Yu L, Wang X, Hao J. Menstrual blood-derived stem cells and its mitochondrial treatment improve the ovarian condition of aged mice. Aging. 2022;14:3826\u201335. https:\/\/doi.org\/10.18632\/aging.204043.","journal-title":"Aging"},{"key":"2175_CR47","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1186\/s13287-023-03568-1","volume":"14","author":"S Zafardoust","year":"2023","unstructured":"Zafardoust S, Kazemnejad S, Fathi-Kazerooni M, Darzi M, Sadeghi MR, Sadeghi Tabar A, et al. The effects of intraovarian injection of autologous menstrual blood-derived mesenchymal stromal cells on pregnancy outcomes in women with poor ovarian response. Stem Cell Res Ther. 2023;14:332. https:\/\/doi.org\/10.1186\/s13287-023-03568-1.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR48","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.reth.2023.11.007","volume":"25","author":"F Kuchakzadeh","year":"2024","unstructured":"Kuchakzadeh F, Ai J, Ebrahimi-Barough S. Tissue engineering and stem cell-based therapeutic strategies for premature ovarian insufficiency. Regen Ther. 2024;25:10\u201323. https:\/\/doi.org\/10.1016\/j.reth.2023.11.007","journal-title":"Regenerative therapy"},{"key":"2175_CR49","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1002\/jemt.23120","volume":"82","author":"MD Manshadi","year":"2019","unstructured":"Manshadi MD, Navid S, Hoshino Y, Daneshi E, Noory P, Abbasi M. The effects of human menstrual blood stem cells-derived granulosa cells on ovarian follicle formation in a rat model of premature ovarian failure. Microsc Res Tech. 2019;82:635\u201342. https:\/\/doi.org\/10.1002\/jemt.23120.","journal-title":"Microsc Res Tech"},{"key":"2175_CR50","doi-asserted-by":"publisher","first-page":"100477","DOI":"10.1016\/j.repbio.2020.100477","volume":"21","author":"A Sheikholeslami","year":"2021","unstructured":"Sheikholeslami A, Kalhor N, Sheykhhasan M, Jannatifar R, Sahraei SS. Evaluating differentiation potential of the human menstrual blood-derived stem cells from infertile women into oocyte-like cells. Reprod Biol. 2021;21:100477. https:\/\/doi.org\/10.1016\/j.repbio.2020.100477.","journal-title":"Reprod Biol"},{"key":"2175_CR51","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1007\/s43032-024-01739-w","volume":"32","author":"H Song","year":"2025","unstructured":"Song H, Zhang R, Liu Y, Wu J, Fan W, Wu J, et al. Menstrual blood-derived endometrial stem cells ameliorate ovarian senescence by relieving oxidative stress-induced inflammation. Reprod Sci (Thousand Oaks, Calif.). 2025;32:1566\u201379. https:\/\/doi.org\/10.1007\/s43032-024-01739-w","journal-title":"Reproductive Sci (Thousand Oaks Calif)"},{"key":"2175_CR52","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1089\/scd.2013.0371","volume":"23","author":"T Liu","year":"2014","unstructured":"Liu T, Huang Y, Zhang J, Qin W, Chi H, Chen J, et al. Transplantation of human menstrual blood stem cells to treat premature ovarian failure in mouse model. Stem Cells Dev. 2014;23:1548\u201357. https:\/\/doi.org\/10.1089\/scd.2013.0371","journal-title":"Stem Cells Dev"},{"key":"2175_CR53","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s13287-016-0458-1","volume":"8","author":"Z Wang","year":"2017","unstructured":"Wang Z, Wang Y, Yang T, Li J, Yang X. Study of the reparative effects of menstrual-derived stem cells on premature ovarian failure in mice. Stem Cell Res Ther. 2017;8:11. https:\/\/doi.org\/10.1186\/s13287-016-0458-1.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR54","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1002\/cbf.3669","volume":"39","author":"NN Yamchi","year":"2021","unstructured":"Yamchi NN, Rahbarghazi R, Bedate AM, Mahdipour M, Nouri M, Khanbabaee R. Menstrual blood CD146(+) mesenchymal stem cells reduced fibrosis rate in the rat model of premature ovarian failure. Cell Biochem Funct. 2021;39:998\u20131008. https:\/\/doi.org\/10.1002\/cbf.3669.","journal-title":"Cell Biochem Funct"},{"key":"2175_CR55","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s13287-018-1101-0","volume":"10","author":"Z Yan","year":"2019","unstructured":"Yan Z, Guo F, Yuan Q, Shao Y, Zhang Y, Wang H, et al. Endometrial mesenchymal stem cells isolated from menstrual blood repaired epirubicin-induced damage to human ovarian granulosa cells by inhibiting the expression of Gadd45b in cell cycle pathway. Stem Cell Res Ther. 2019;10:4. https:\/\/doi.org\/10.1186\/s13287-018-1101-0.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR56","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/s12015-018-9867-0","volume":"15","author":"P Feng","year":"2019","unstructured":"Feng P, Li P, Tan J. Human menstrual blood-derived stromal cells promote recovery of premature ovarian insufficiency via regulating the ECM-dependent FAK\/AKT signaling. Stem Cell Rev Rep. 2019;15:241\u201355. https:\/\/doi.org\/10.1007\/s12015-018-9867-0","journal-title":"Stem cell reviews Rep"},{"key":"2175_CR57","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.reprotox.2022.03.012","volume":"110","author":"X Fu","year":"2022","unstructured":"Fu X, Zhang S, Li T, Zhang R, Lu Y, Cheng H, et al. Menstrual blood-derived endometrial stem cells ameliorate the viability of ovarian granulosa cells injured by cisplatin through activating autophagy. Reprod Toxicol (Elmsford, NY). 2022;110:39\u201348. https:\/\/doi.org\/10.1016\/j.reprotox.2022.03.012","journal-title":"Reproductive Toxicol (Elmsford, NY)"},{"key":"2175_CR58","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1186\/s13287-021-02255-3","volume":"12","author":"S Zhang","year":"2021","unstructured":"Zhang S, Huang B, Su P, Chang Q, Li P, Song A, et al. Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency. Stem Cell Res Ther. 2021;12:178. https:\/\/doi.org\/10.1186\/s13287-021-02255-3.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR59","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1016\/s0140-6736(04)17403-5","volume":"364","author":"LC Giudice","year":"2004","unstructured":"Giudice LC, Kao LC. Endometriosis. Lancet. 2004;364:1789\u201399. https:\/\/doi.org\/10.1016\/s0140-6736(04)17403-5.","journal-title":"England)"},{"key":"2175_CR60","doi-asserted-by":"publisher","unstructured":"Taylor RN, Lebovic DI, Mueller MD. Angiogenic factors in endometriosis. Ann NY Acad Sci . 2002; 955:89\u2013100; discussion 18, 396\u2013406. https:\/\/doi.org\/10.1111\/j.1749-6632.2002.tb02769.x","DOI":"10.1111\/j.1749-6632.2002.tb02769.x"},{"key":"2175_CR61","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.thromres.2009.06.013","volume":"124","author":"G Krikun","year":"2009","unstructured":"Krikun G, Lockwood CJ, Paidas MJ. Tissue factor and the endometrium: from physiology to pathology. Thromb Res. 2009;124:393\u20136. https:\/\/doi.org\/10.1016\/j.thromres.2009.06.013.","journal-title":"Thromb Res"},{"key":"2175_CR62","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1055\/s-0035-1564609","volume":"33","author":"D Hufnagel","year":"2015","unstructured":"Hufnagel D, Li F, Cosar E, Krikun G, Taylor HS. The role of stem cells in the etiology and pathophysiology of endometriosis. Semin Reprod Med. 2015;33:333\u201340. https:\/\/doi.org\/10.1055\/s-0035-1564609.","journal-title":"Semin Reprod Med"},{"key":"2175_CR63","doi-asserted-by":"publisher","first-page":"e070750","DOI":"10.1136\/bmj-2022-070750","volume":"379","author":"AW Horne","year":"2022","unstructured":"Horne AW, Missmer SA. Pathophysiology, diagnosis, and management of endometriosis. BMJ (Clin Res Ed). 2022;379:e070750. https:\/\/doi.org\/10.1136\/bmj-2022-070750","journal-title":"BMJ (Clinical Res ed)"},{"key":"2175_CR64","doi-asserted-by":"publisher","unstructured":"Boucher A, Brichant G, Gridelet V, Nisolle M, Ravet S, Timmermans M, et al. Implantation failure in endometriosis patients: etiopathogenesis. J Clin Med. 2022;11. https:\/\/doi.org\/10.3390\/jcm11185366.","DOI":"10.3390\/jcm11185366"},{"key":"2175_CR65","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1056\/NEJMra0804690","volume":"360","author":"SE Bulun","year":"2009","unstructured":"Bulun SE. Endometriosis. N Engl J Med. 2009;360:268\u201379. https:\/\/doi.org\/10.1056\/NEJMra0804690.","journal-title":"N Engl J Med"},{"key":"2175_CR66","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1093\/humupd\/dmv045","volume":"22","author":"U Leone Roberti Maggiore","year":"2016","unstructured":"Leone Roberti Maggiore U, Ferrero S, Mangili G, Bergamini A, Inversetti A, Giorgione V, et al. A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes. Hum Reprod Update. 2016;22:70\u2013103. https:\/\/doi.org\/10.1093\/humupd\/dmv045.","journal-title":"Hum Reprod Update"},{"key":"2175_CR67","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1007\/s13669-017-0187-1","volume":"6","author":"P Parasar","year":"2017","unstructured":"Parasar P, Ozcan P, Terry KL. Endometriosis: epidemiology, diagnosis and clinical management. Curr Obstet Gynecol Rep. 2017;6:34\u201341. https:\/\/doi.org\/10.1007\/s13669-017-0187-1.","journal-title":"Curr Obstet Gynecol Rep"},{"key":"2175_CR68","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.ejogrb.2016.12.002","volume":"210","author":"M Hirsch","year":"2017","unstructured":"Hirsch M, Duffy JMN, Deguara CS, Davis CJ, Khan KS. Diagnostic accuracy of cancer antigen 125 (CA125) for endometriosis in symptomatic women: A multi-center study. Eur J Obstet Gynecol Reprod Biol. 2017;210:102\u201307. https:\/\/doi.org\/10.1016\/j.ejogrb.2016.12.002.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2175_CR69","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1093\/biolre\/ioaa011","volume":"102","author":"Y Liu","year":"2020","unstructured":"Liu Y, Zhang Z, Yang F, Wang H, Liang S, Wang H, et al. The role of endometrial stem cells in the pathogenesis of endometriosis and their application to its early diagnosis. Biol Reprod. 2020;102:1153\u201359. https:\/\/doi.org\/10.1093\/biolre\/ioaa011.","journal-title":"Biol Reprod"},{"key":"2175_CR70","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1186\/s13104-020-05070-w","volume":"13","author":"TH Madjid","year":"2020","unstructured":"Madjid TH, Jumadi, Judistiani RTD, Hernowo BS, Faried A. Detection of endometriosis using immunocytochemistry of P450 Aromatase expressions in eutopic endometrial cells obtained from menstrual sloughing: a diagnostic study. BMC Res Notes. 2020;13:233. https:\/\/doi.org\/10.1186\/s13104-020-05070-w.","journal-title":"BMC Res Notes"},{"key":"2175_CR71","doi-asserted-by":"publisher","first-page":"100","DOI":"10.5115\/acb.21.169","volume":"55","author":"SS Sahraei","year":"2022","unstructured":"Sahraei SS, Kowsari A, Asl FD, Sheykhhasan M, Naserpoor L, Sheikholeslami A. Evaluating the effect of conditioned medium from endometrial stem cells on endometriosis-derived endometrial stem cells. Anat Cell Biol. 2022;55:100\u201308. https:\/\/doi.org\/10.5115\/acb.21.169","journal-title":"Anat cell biology"},{"key":"2175_CR72","doi-asserted-by":"publisher","first-page":"100788","DOI":"10.1016\/j.repbio.2023.100788","volume":"23","author":"F Davoodi Asl","year":"2023","unstructured":"Davoodi Asl F, Sahraei SS, Kalhor N, Fazaeli H, Sheykhhasan M, Soleimani Moud S, et al. Promising effects of exosomes from menstrual blood-derived mesenchymal stem cells on endometriosis. Reprod Biol. 2023;23:100788. https:\/\/doi.org\/10.1016\/j.repbio.2023.100788.","journal-title":"Reprod Biol"},{"key":"2175_CR73","doi-asserted-by":"publisher","first-page":"8347","DOI":"10.1038\/s41598-023-35373-4","volume":"13","author":"Y Zhang","year":"2023","unstructured":"Zhang Y, He T, Lin T, Guo Q, Huo C, Roberts SZ, et al. Novel in vivo endometriotic models associated eutopic endometrium by implanting menstrual blood-derived stromal cells from patients with endometriosis. Sci Rep. 2023;13:8347. https:\/\/doi.org\/10.1038\/s41598-023-35373-4.","journal-title":"Sci Rep"},{"key":"2175_CR74","doi-asserted-by":"publisher","first-page":"2447","DOI":"10.3892\/etm.2016.3671","volume":"12","author":"AP Domnina","year":"2016","unstructured":"Domnina AP, Novikova PV, Lyublinskaya OG, Zenin VV, Fridlyanskaya II, Mikhailov VM, et al. Mesenchymal stem cells with irreversibly arrested proliferation stimulate decidua development in rats. Exp Ther Med. 2016;12:2447\u201354. https:\/\/doi.org\/10.3892\/etm.2016.3671","journal-title":"Experimental therapeutic Med"},{"key":"2175_CR75","doi-asserted-by":"publisher","first-page":"4599","DOI":"10.1038\/srep04599","volume":"4","author":"K Sugawara","year":"2014","unstructured":"Sugawara K, Hamatani T, Yamada M, Ogawa S, Kamijo S, Kuji N, et al. Derivation of human decidua-like cells from amnion and menstrual blood. Sci Rep. 2014;4:4599. https:\/\/doi.org\/10.1038\/srep04599.","journal-title":"Sci Rep"},{"key":"2175_CR76","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1097\/gco.0000000000000378","volume":"29","author":"CA Salazar","year":"2017","unstructured":"Salazar CA, Isaacson K, Morris S. A comprehensive review of Asherman\u2019s syndrome: causes, symptoms and treatment options. Curr Opin Obst Gynecol. 2017;29:249\u201356. https:\/\/doi.org\/10.1097\/gco.0000000000000378.","journal-title":"Curr Opin Obst Gynecol"},{"key":"2175_CR77","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1093\/humrep\/dez001","volume":"34","author":"H Zhu","year":"2019","unstructured":"Zhu H, Pan Y, Jiang Y, Li J, Zhang Y, Zhang S. Activation of the Hippo\/TAZ pathway is required for menstrual stem cells to suppress myofibroblast and inhibit transforming growth factor \u03b2 signaling in human endometrial stromal cells. Hum Reprod (Oxford England). 2019;34:635\u201345. https:\/\/doi.org\/10.1093\/humrep\/dez001.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2175_CR78","doi-asserted-by":"publisher","first-page":"2723","DOI":"10.1093\/humrep\/dew235","volume":"31","author":"J Tan","year":"2016","unstructured":"Tan J, Li P, Wang Q, Li Y, Li X, Zhao D, et al. Autologous menstrual blood-derived stromal cells transplantation for severe Asherman\u2019s syndrome. Hum Reprod (Oxford England). 2016;31:2723\u201329. https:\/\/doi.org\/10.1093\/humrep\/dew235.","journal-title":"Hum Reprod (Oxford England)"},{"key":"2175_CR79","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s13287-019-1155-7","volume":"10","author":"S Zhang","year":"2019","unstructured":"Zhang S, Li P, Yuan Z, Tan J. Platelet-rich plasma improves therapeutic effects of menstrual blood-derived stromal cells in rat model of intrauterine adhesion. Stem Cell Res Ther. 2019;10:61. https:\/\/doi.org\/10.1186\/s13287-019-1155-7.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR80","doi-asserted-by":"publisher","first-page":"3325","DOI":"10.1007\/s43032-023-01282-0","volume":"30","author":"S Zhang","year":"2023","unstructured":"Zhang S, Zhang R, Yin X, Lu Y, Cheng H, Pan Y, et al. MenSCs transplantation improve the viability of injured endometrial cells through activating PI3K\/Akt pathway. Reprod Sci (Thousand Oaks, Calif.). 2023;30:3325\u201338. https:\/\/doi.org\/10.1007\/s43032-023-01282-0","journal-title":"Reproductive Sci (Thousand Oaks Calif)"},{"key":"2175_CR81","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1186\/s13287-024-03996-7","volume":"15","author":"B Luo","year":"2024","unstructured":"Luo B, Zeng X, Luo L. Intrauterine adhesions repair with menstrual blood-derived mesenchymal stem cells via CXCL13-CXCR5 signal axis and its mechanism. Stem Cell Res Ther. 2024;15:380. https:\/\/doi.org\/10.1186\/s13287-024-03996-7.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR82","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.reprotox.2022.03.001","volume":"109","author":"X Hu","year":"2022","unstructured":"Hu X, Dai Z, Pan R, Zhang Y, Liu L, Wang Y, et al. Long-term transplantation human menstrual blood mesenchymal stem cell loaded collagen scaffolds repair endometrium histological injury. Reprod Toxicol (Elmsford, NY). 2022;109:53\u201360. https:\/\/doi.org\/10.1016\/j.reprotox.2022.03.001","journal-title":"Reproductive Toxicol (Elmsford, NY)"},{"key":"2175_CR83","first-page":"4941","volume":"12","author":"L Chen","year":"2020","unstructured":"Chen L, Guo L, Chen F, Xie Y, Zhang H, Quan P, et al. Transplantation of menstrual blood-derived mesenchymal stem cells (MbMSCs) promotes the regeneration of mechanical injuried endometrium. Am J Transl Res. 2020;12:4941\u201354.","journal-title":"Am J translational Res"},{"key":"2175_CR84","doi-asserted-by":"publisher","first-page":"104486","DOI":"10.1016\/j.rbmo.2024.104486","volume":"50","author":"S Huang","year":"2025","unstructured":"Huang S, Cheng C, Wang Z, Li R, Li W, Yu K, et al. Low-intensity-pulsed-ultrasound-treated menstrual-blood-derived mesenchymal stem cells repair endometrial injury by PI3K\/AKT pathway inhibition. Reprod Biomed Online. 2025;50:104486. https:\/\/doi.org\/10.1016\/j.rbmo.2024.104486.","journal-title":"Reprod Biomed Online"},{"key":"2175_CR85","doi-asserted-by":"publisher","first-page":"8496","DOI":"10.1039\/d5tb00902b","volume":"13","author":"P Liao","year":"2025","unstructured":"Liao P, Xie J, Wang J, Lin J, Zhang X, Qin C, et al. Effective repair of endometrial injury in rats using enzyme cross-linked gelatin hydrogels with human menstrual blood-derived stem cells. J Mater Chem B. 2025;13:8496\u2013509. https:\/\/doi.org\/10.1039\/d5tb00902b.","journal-title":"J Mater Chem B"},{"key":"2175_CR86","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1016\/j.fertnstert.2007.04.031","volume":"89","author":"T El-Toukhy","year":"2008","unstructured":"El-Toukhy T, Coomarasamy A, Khairy M, Sunkara K, Seed P, Khalaf Y, et al. The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles. Fertil Steril. 2008;89:832\u20139. https:\/\/doi.org\/10.1016\/j.fertnstert.2007.04.031.","journal-title":"Fertil Steril"},{"key":"2175_CR87","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/s1472-6483(10)60428-2","volume":"18","author":"B Kumbak","year":"2009","unstructured":"Kumbak B, Erden HF, Tosun S, Akbas H, Ulug U, Bah\u00e7eci M. Outcome of assisted reproduction treatment in patients with endometrial thickness less than 7\u00a0mm. Reprod Biomed Online. 2009;18:79\u201384. https:\/\/doi.org\/10.1016\/s1472-6483(10)60428-2.","journal-title":"Reprod Biomed Online"},{"key":"2175_CR88","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1007\/bf01135678","volume":"7","author":"Y Gonen","year":"1990","unstructured":"Gonen Y, Casper RF. Prediction of implantation by the sonographic appearance of the endometrium during controlled ovarian stimulation for in vitro fertilization (IVF). Assist Reprod Genet. 1990;7:146\u201352. https:\/\/doi.org\/10.1007\/bf01135678.","journal-title":"Assist Reprod Genet"},{"key":"2175_CR89","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.fertnstert.2015.05.036","volume":"104","author":"JA Gingold","year":"2015","unstructured":"Gingold JA, Lee JA, Rodriguez-Purata J, Whitehouse MC, Sandler B, Grunfeld L, et al. Endometrial pattern, but not endometrial thickness, affects implantation rates in euploid embryo transfers. Fertil Steril. 2015;104:620\u2013e85. https:\/\/doi.org\/10.1016\/j.fertnstert.2015.05.036.","journal-title":"Fertil Steril"},{"key":"2175_CR90","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4103\/0974-1208.178632","volume":"9","author":"N Mahajan","year":"2016","unstructured":"Mahajan N, Sharma S. The endometrium in assisted reproductive technology: How thin is thin? J Hum Reprod Sci. 2016;9:3\u20138. https:\/\/doi.org\/10.4103\/0974-1208.178632","journal-title":"J Hum reproductive Sci"},{"key":"2175_CR91","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/j.fertnstert.2008.01.029","volume":"91","author":"I Miwa","year":"2009","unstructured":"Miwa I, Tamura H, Takasaki A, Yamagata Y, Shimamura K, Sugino N. Pathophysiologic features of thin endometrium. Fertil Steril. 2009;91:998\u20131004. https:\/\/doi.org\/10.1016\/j.fertnstert.2008.01.029.","journal-title":"Fertil Steril"},{"key":"2175_CR92","doi-asserted-by":"publisher","first-page":"1476","DOI":"10.21037\/atm-21-4652","volume":"9","author":"M Zhao","year":"2021","unstructured":"Zhao M, Chi F, Zhang T, Teng X, Li K. Human menstrual blood-derived mesenchymal stem cells regulation of the EGF\/Ras p21 pathway as a potential therapeutic target for thin endometrium. Ann Transl Med. 2021;9:1476. https:\/\/doi.org\/10.21037\/atm-21-4652","journal-title":"Annals Transl Med"},{"key":"2175_CR93","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1530\/REP-16-0286","volume":"152","author":"Y Zhang","year":"2016","unstructured":"Zhang Y, Lin X, Dai Y, Hu X, Zhu H, Jiang Y, et al. Endometrial stem cells repair injured endometrium and induce angiogenesis via AKT and ERK pathways. Reprod (Cambridge England). 2016;152:389\u2013402. http:\/\/doi.org\/10.1530\/rep-16-0286.","journal-title":"Reprod (Cambridge England)"},{"key":"2175_CR94","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.repbio.2018.06.003","volume":"18","author":"H Zhu","year":"2018","unstructured":"Zhu H, Jiang Y, Pan Y, Shi L, Zhang S. Human menstrual blood-derived stem cells promote the repair of impaired endometrial stromal cells by activating the p38 MAPK and AKT signaling pathways. Reprod Biol. 2018;18:274\u201381. https:\/\/doi.org\/10.1016\/j.repbio.2018.06.003.","journal-title":"Reprod Biol"},{"key":"2175_CR95","doi-asserted-by":"publisher","first-page":"813","DOI":"10.3892\/mmr.2018.9744","volume":"19","author":"J Hu","year":"2019","unstructured":"Hu J, Song K, Zhang J, Zhang Y, Tan BZ. Effects of menstrual blood\u2013derived stem cells on endometrial injury repair. Mol Med Rep. 2019;19:813\u201320. https:\/\/doi.org\/10.3892\/mmr.2018.9744.","journal-title":"Mol Med Rep"},{"key":"2175_CR96","doi-asserted-by":"publisher","first-page":"1662","DOI":"10.1007\/s43032-024-01458-2","volume":"31","author":"K Chen","year":"2024","unstructured":"Chen K, Wang H, Zhao X, Wang J, Jin Q, Tong X, et al. A novel method to repair thin endometrium and restore fertility based on menstruation-derived stem cell. Reprod Sci (Thousand Oaks, Calif.). 2024;31:1662\u201373. https:\/\/doi.org\/10.1007\/s43032-024-01458-2","journal-title":"Reproductive Sci (Thousand Oaks Calif)"},{"key":"2175_CR97","doi-asserted-by":"publisher","first-page":"102827","DOI":"10.1016\/j.tice.2025.102827","volume":"95","author":"Y Wang","year":"2025","unstructured":"Wang Y, Zhao Y, Liu Y, Wang J, Liu F. Effects of mesenchymal stem cells on repair of injured endometrium in mice. Tissue Cell. 2025;95:102827. https:\/\/doi.org\/10.1016\/j.tice.2025.102827.","journal-title":"Tissue Cell"},{"key":"2175_CR98","doi-asserted-by":"publisher","unstructured":"Abu-Musa A, Haahr T, Humaidan P. Novel Physiology and Definition of Poor Ovarian Response; Clinical Recommendations. Int J Mol Sci. 2020;21. https:\/\/doi.org\/10.3390\/ijms21062110.","DOI":"10.3390\/ijms21062110"},{"key":"2175_CR99","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s12015-020-09969-6","volume":"16","author":"S Zafardoust","year":"2020","unstructured":"Zafardoust S, Kazemnejad S, Darzi M, Fathi-Kazerooni M, Rastegari H, Mohammadzadeh A. Improvement of pregnancy rate and live birth rate in poor ovarian responders by intraovarian administration of autologous menstrual blood derived- mesenchymal stromal cells: phase I\/II clinical trial. Stem Cell Rev Rep. 2020;16:755\u201363. https:\/\/doi.org\/10.1007\/s12015-020-09969-6","journal-title":"Stem cell reviews Rep"},{"key":"2175_CR100","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1186\/s13287-025-04278-6","volume":"16","author":"S Zafardoust","year":"2025","unstructured":"Zafardoust S, Didar H, Ganagard MG, Tavakoli M, Arefi S, Arjmandinaloo S, et al. Intra-ovarian injection of autologous menstrual blood-derived-mesenchymal stromal cells: a safe and promising method to improve pregnancy rate in poor ovarian responders. Stem Cell Res Ther. 2025;16:171. https:\/\/doi.org\/10.1186\/s13287-025-04278-6.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR101","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.rbmo.2013.08.011","volume":"28","author":"C Coughlan","year":"2014","unstructured":"Coughlan C, Ledger W, Wang Q, Liu F, Demirol A, Gurgan T, et al. Recurrent implantation failure: definition and management. Reprod Biomed Online. 2014;28:14\u201338. https:\/\/doi.org\/10.1016\/j.rbmo.2013.08.011.","journal-title":"Reprod Biomed Online"},{"key":"2175_CR102","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/s12958-018-0414-2","volume":"16","author":"A Bashiri","year":"2018","unstructured":"Bashiri A, Halper KI, Orvieto R. Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions. Reprod Biol Endocrinol. 2018;16:121. https:\/\/doi.org\/10.1186\/s12958-018-0414-2","journal-title":"Reproductive biology endocrinology"},{"key":"2175_CR103","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.fertnstert.2006.05.064","volume":"87","author":"KS Richter","year":"2007","unstructured":"Richter KS, Bugge KR, Bromer JG, Levy MJ. Relationship between endometrial thickness and embryo implantation, based on 1,294 cycles of in vitro fertilization with transfer of two blastocyst-stage embryos. Fertil Steril. 2007;87:53\u20139. https:\/\/doi.org\/10.1016\/j.fertnstert.2006.05.064.","journal-title":"Fertil Steril"},{"key":"2175_CR104","doi-asserted-by":"publisher","first-page":"118","DOI":"10.5935\/1518-0557.20190061","volume":"24","author":"AE Tersoglio","year":"2020","unstructured":"Tersoglio AE, Tersoglio S, Salatino DR, Castro M, Gonzalez A, Hinojosa M, et al. Regenerative therapy by endometrial mesenchymal stem cells in thin endometrium with repeated implantation failure. A novel strategy. JBRA Assist Reprod. 2020;24:118\u201327. https:\/\/doi.org\/10.5935\/1518-0557.20190061.","journal-title":"JBRA Assist Reprod"},{"key":"2175_CR105","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1089\/cell.2024.0071","volume":"27","author":"C Ma","year":"2025","unstructured":"Ma C, Yi Y, Guan C. Menstrual blood-derived mesenchymal stem cells improve endometrial receptivity in a mouse model of embryonic implantation dysfunction. Cell Reprogram. 2025;27:124\u201333. https:\/\/doi.org\/10.1089\/cell.2024.0071","journal-title":"Cell reprogramming"},{"key":"2175_CR106","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1089\/ten.tea.2020.0034","volume":"26","author":"MF Gon\u00e7alves","year":"2020","unstructured":"Gon\u00e7alves MF, Asensi KD, Nascimento ALL, de Barros JHO, Santos RA, Andrade CBV, et al. Human menstrual blood-derived mesenchymal cells improve mouse embryonic development. Tissue Eng Part A. 2020;26:769\u201379. https:\/\/doi.org\/10.1089\/ten.tea.2020.0034.","journal-title":"Tissue Eng Part A"},{"key":"2175_CR107","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1093\/biolre\/ioy263","volume":"100","author":"F Marinaro","year":"2019","unstructured":"Marinaro F, Mac\u00edas-Garc\u00eda B, S\u00e1nchez-Margallo FM, Bl\u00e1zquez R, \u00c1lvarez V, Matilla E, et al. Extracellular vesicles derived from endometrial human mesenchymal stem cells enhance embryo yield and quality in an aged murine model. Biol Reprod. 2019;100:1180\u201392. https:\/\/doi.org\/10.1093\/biolre\/ioy263.","journal-title":"Biol Reprod"},{"issue":"Suppl 2","key":"2175_CR108","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1111\/rda.13314","volume":"53","author":"F Marinaro","year":"2018","unstructured":"Marinaro F, Pericuesta E, S\u00e1nchez-Margallo FM, Casado JG, \u00c1lvarez V, Matilla E, et al. Extracellular vesicles derived from endometrial human mesenchymal stem cells improve IVF outcome in an aged murine model. Reprod Domest Anim. 2018;53(Suppl 2):46\u20139. https:\/\/doi.org\/10.1111\/rda.13314","journal-title":"Reprod Domest Anim = Zuchthygiene"},{"key":"2175_CR109","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1186\/s13287-023-03551-w","volume":"14","author":"S Zhang","year":"2023","unstructured":"Zhang S, Yahaya BH, Pan Y, Liu Y, Lin J. Menstrual blood-derived endometrial stem cell, a unique and promising alternative in the stem cell-based therapy for chemotherapy-induced premature ovarian insufficiency. Stem Cell Res Ther. 2023;14:327. https:\/\/doi.org\/10.1186\/s13287-023-03551-w.","journal-title":"Stem Cell Res Ther"},{"key":"2175_CR110","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1177\/1933719117725824","volume":"25","author":"SM Almasry","year":"2018","unstructured":"Almasry SM, Elfayomy AK, El-Sherbiny MH. Regeneration of the fallopian tube mucosa using bone marrow mesenchymal stem cell transplantation after induced chemical injury in a rat model. Reprod Sci (Thousand Oaks, Calif.). 2018;25:773\u201381. https:\/\/doi.org\/10.1177\/1933719117725824","journal-title":"Reproductive Sci (Thousand Oaks Calif)"},{"key":"2175_CR111","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s00404-019-05209-6","volume":"300","author":"W Liao","year":"2019","unstructured":"Liao W, Tang X, Li X, Li T. Therapeutic effect of human umbilical cord mesenchymal stem cells on tubal factor infertility using a chronic salpingitis murine model. Arch Gynecol Obstet. 2019;300:421\u201329. https:\/\/doi.org\/10.1007\/s00404-019-05209-6.","journal-title":"Arch Gynecol Obstet"}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-026-02175-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43032-026-02175-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43032-026-02175-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:35:27Z","timestamp":1787319327000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43032-026-02175-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,21]]},"references-count":111,"alternative-id":["2175"],"URL":"https:\/\/doi.org\/10.1007\/s43032-026-02175-8","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,21]]},"assertion":[{"value":"4 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors contributed to the writing of the article and thoroughly reviewed the manuscript. They have authorized the publication of this article.","order":3,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":4,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}