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The raw and processed sequencing data are publicly available in the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO) repository under accession GSE100197 and can be accessed at:\n                      \n                      .The external validation dataset, comprising 20 EOPE and 20 control samples, is publicly available in the NCBI GEO repository [\n                      \n                      ] under accession GSE44667 and can be accessed at:\n                      \n                      .The machine learning analysis was conducted using the WEKA platform.","order":1,"name":"Ethics","label":"Data Disposition","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This is a theoretical article based on published anonymized data. 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