{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T02:22:50Z","timestamp":1780366970718,"version":"3.54.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T00:00:00Z","timestamp":1635292800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T00:00:00Z","timestamp":1635292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Spine Deform"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1007\/s43390-021-00422-3","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T14:03:53Z","timestamp":1635343433000},"page":"285-294","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Management of NF-1 dystrophic scoliosis associated with rib heads dislocation into the spinal canal in neurological intact patients: a systematic literature review"],"prefix":"10.1007","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7327-8703","authenticated-orcid":false,"given":"Martin M.","family":"Estefan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaston","family":"Camino-Willhuber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago T.","family":"Bosio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Puigdevall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben A.","family":"Maenza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,27]]},"reference":[{"key":"422_CR1","volume-title":"GeneReviews(\u00ae)","author":"JM Friedman","year":"1993","unstructured":"Friedman JM (1993) Neurofibromatosis 1. In: Pagon RA, Adam MP, Ardinger HH et al (eds) GeneReviews(\u00ae). University of Washington, Seattle"},{"issue":"3","key":"422_CR2","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1097\/01.bpo.0000217719.10728.39","volume":"26","author":"AH Crawford","year":"2006","unstructured":"Crawford AH, Schorry EK (2006) Neurofibromatosis update. J Pediatr Orthop 26(3):413\u2013423. https:\/\/doi.org\/10.1097\/01.bpo.0000217719.10728.39","journal-title":"J Pediatr Orthop"},{"key":"422_CR3","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/00003086-200208000-00013","volume":"401","author":"MG Vitale","year":"2002","unstructured":"Vitale MG, Guha A, Skaggs DL (2002) Orthopaedic manifestations of neurofibromatosis in children: an update. Clin Orthop Relat Res 401:107\u2013118. https:\/\/doi.org\/10.1097\/00003086-200208000-00013","journal-title":"Clin Orthop Relat Res"},{"issue":"8","key":"422_CR4","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/S1474-4422(14)70063-8","volume":"13","author":"AC Hirbe","year":"2014","unstructured":"Hirbe AC, Gutmann DH (2014) Neurofibromatosis type 1: a multidisciplinary approach to care. Lancet Neurol 13(8):834\u2013843. https:\/\/doi.org\/10.1016\/S1474-4422(14)70063-8","journal-title":"Lancet Neurol"},{"issue":"5","key":"422_CR5","doi-asserted-by":"publisher","first-page":"677","DOI":"10.2106\/00004623-197961050-00006","volume":"61","author":"RB Winter","year":"1979","unstructured":"Winter RB, Moe JH, Bradford DS et al (1979) Spine deformity in neurofibromatosis. A review of one hundred and two patients. J Bone Joint Surg Am 61(5):677\u2013694","journal-title":"J Bone Joint Surg Am"},{"issue":"8 Suppl","key":"422_CR6","doi-asserted-by":"publisher","first-page":"S244","DOI":"10.1097\/00007632-199208001-00005","volume":"17","author":"BA Akbarnia","year":"1992","unstructured":"Akbarnia BA, Gabriel KR, Beckman E et al (1992) Prevalence of scoliosis in neurofibromatosis. Spine 17(8 Suppl):S244\u2013S248. https:\/\/doi.org\/10.1097\/00007632-199208001-00005","journal-title":"Spine"},{"issue":"5","key":"422_CR7","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1111\/j.1399-0004.2005.00410.x","volume":"67","author":"S Alwan","year":"2005","unstructured":"Alwan S, Tredwell SJ, Friedman JM (2005) Is osseous dysplasia a primary feature of neurofibromatosis 1 (NF1)? Clin Genet 67(5):378\u2013390. https:\/\/doi.org\/10.1111\/j.1399-0004.2005.00410.x","journal-title":"Clin Genet"},{"issue":"5","key":"422_CR8","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1016\/j.jspd.2018.02.011","volume":"6","author":"AN Larson","year":"2018","unstructured":"Larson AN, Ledonio CGT, Brearley AM et al (2018) Predictive value and interrater reliability of radiographic factors in neurofibromatosis patients with dystrophic scoliosis. Spine Deform 6(5):560\u2013567. https:\/\/doi.org\/10.1016\/j.jspd.2018.02.011","journal-title":"Spine Deform"},{"issue":"6","key":"422_CR9","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1097\/00004694-200011000-00020","volume":"20","author":"KI Khoshhal","year":"2000","unstructured":"Khoshhal KI, Ellis RD (2000) Paraparesis after posterior spinal fusion in neurofibromatosis secondary to rib displacement: case report and literature review. J Pediatr Orthop 20(6):799\u2013801. https:\/\/doi.org\/10.1097\/00004694-200011000-00020","journal-title":"J Pediatr Orthop"},{"issue":"7","key":"422_CR10","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.2106\/00004623-198870070-00023","volume":"70","author":"MR Major","year":"1988","unstructured":"Major MR, Huizenga BA (1988) Spinal cord compression by displaced ribs in neurofibromatosis. A report of three cases. J Bone Joint Surg Am 70(7):1100\u20131102","journal-title":"J Bone Joint Surg Am"},{"issue":"1","key":"422_CR11","first-page":"57","volume":"89","author":"B Legrand","year":"2003","unstructured":"Legrand B, Filipe G, Blamoutier A et al (2003) Intraspinal rib penetration in four patients in neurofibromatosis vertebral deformities. Rev Chir Orthop Reparatrice Appar Mot 89(1):57\u201361","journal-title":"Rev Chir Orthop Reparatrice Appar Mot"},{"issue":"12","key":"422_CR12","doi-asserted-by":"publisher","first-page":"1902","DOI":"10.1007\/s00247-010-1789-1","volume":"40","author":"J Ton","year":"2010","unstructured":"Ton J, Stein-Wexler R, Yen P et al (2010) Rib head protrusion into the central canal in type 1 neurofibromatosis. Pediatr Radiol 40(12):1902\u20131909. https:\/\/doi.org\/10.1007\/s00247-010-1789-1","journal-title":"Pediatr Radiol"},{"key":"422_CR13","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1748-7161-1-10","volume":"1","author":"A Gkiokas","year":"2006","unstructured":"Gkiokas A, Hadzimichalis S, Vasiliadis E et al (2006) Painful rib hump: a new clinical sign for detecting intraspinal rib displacement in scoliosis due to neurofibromatosis. Scoliosis 1:10. https:\/\/doi.org\/10.1186\/1748-7161-1-10","journal-title":"Scoliosis"},{"issue":"3","key":"422_CR14","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s10195-008-0010-x","volume":"9","author":"M Cappella","year":"2008","unstructured":"Cappella M, Bettini N, Dema E et al (2008) Late post-operative paraparesis after rib penetration of the spinal canal in a patient with neurofibromatous scoliosis. J Orthop Traumatol 9(3):163\u2013166. https:\/\/doi.org\/10.1007\/s10195-008-0010-x","journal-title":"J Orthop Traumatol"},{"issue":"7","key":"422_CR15","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1007\/BF02015788","volume":"25","author":"SV Kamath","year":"1995","unstructured":"Kamath SV, Kleinman PK, Ragland RL et al (1995) Intraspinaldislocation of the rib in neuroibromatosis: a case report. Pediatr Radiol 25(7):538\u2013539. https:\/\/doi.org\/10.1007\/BF02015788","journal-title":"Pediatr Radiol"},{"issue":"23","key":"422_CR16","doi-asserted-by":"publisher","first-page":"E881","DOI":"10.1097\/BRS.0b013e318184efad","volume":"33","author":"N Yalcin","year":"2008","unstructured":"Yalcin N, Bar-on E, Yazici M (2008) Impingement of spinal cord by dislocated rib in dystrophic scoliosis secondary to neuroibromatosis type 1: radiological signs and management strategies. Spine 33(23):E881\u2013E886. https:\/\/doi.org\/10.1097\/BRS.0b013e318184efad","journal-title":"Spine"},{"issue":"1","key":"422_CR17","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1097\/BPO.0b013e3182032029","volume":"31","author":"MH Abdulian","year":"2011","unstructured":"Abdulian MH, Liu RW, Son-Hing JP et al (2011) Double rib penetration of the spinal canal in a patient with neurofibromatosis. J Pediatr Orthop 31(1):6\u201310. https:\/\/doi.org\/10.1097\/BPO.0b013e3182032029","journal-title":"J Pediatr Orthop"},{"issue":"13","key":"422_CR18","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31824d590d","volume":"78","author":"R Krishnakumar","year":"2012","unstructured":"Krishnakumar R, Renjitkumar J (2012) Teaching neuroimages: rib penciling and intraspinal dislocation of rib heads in type 1 neurofibromatosis. Neurology 78(13):e85. https:\/\/doi.org\/10.1212\/WNL.0b013e31824d590d","journal-title":"Neurology"},{"issue":"12","key":"422_CR19","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.6061\/clinics\/2013(12)08","volume":"68","author":"D Sun","year":"2013","unstructured":"Sun D, Dai F, Liu YY et al (2013) Posterior-only spinal fusion without rib head resection for treating type I neurofibromatosis with intra-canal rib head dislocation. Clinics (Sao Paulo) 68(12):1521\u20131527. https:\/\/doi.org\/10.6061\/clinics\/2013(12)08","journal-title":"Clinics (Sao Paulo)"},{"issue":"7","key":"422_CR20","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1007\/s00586-014-3741-9","volume":"24","author":"S Mao","year":"2015","unstructured":"Mao S, Shi B, Wang S et al (2015) Migration of the penetrated rib head following deformity correction surgery without rib head excision in dystrophic scoliosis secondary to type 1 Neurofibromatosis. Eur Spine J 24(7):1502\u20131509. https:\/\/doi.org\/10.1007\/s00586-014-3741-9","journal-title":"Eur Spine J"},{"key":"422_CR21","doi-asserted-by":"publisher","first-page":"2908915","DOI":"10.1155\/2016\/2908915","volume":"2016","author":"GI Mataliotakis","year":"2016","unstructured":"Mataliotakis GI, Bounakis N, Garrido-Stratenwerth E (2016) Surgical management of intracanal rib head dislocation in neurofibromatosis type 1 dystrophic kyphoscoliosis: report of two cases and literature review. Case Rep Orthop 2016:2908915. https:\/\/doi.org\/10.1155\/2016\/2908915","journal-title":"Case Rep Orthop"},{"issue":"1","key":"422_CR22","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1097\/BSD.0000000000000240","volume":"30","author":"S Cai","year":"2017","unstructured":"Cai S, Zhang J, Shen J et al (2017) Posterior correction without rib-head resection for patients with neurofibromatosis type 1, dystrophic scoliosis, and rib-head protrusion into the spinal canal. Clin Spine Surg 30(1):32\u201337. https:\/\/doi.org\/10.1097\/BSD.0000000000000240","journal-title":"Clin Spine Surg"},{"issue":"14","key":"422_CR23","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003292","volume":"95","author":"X Zhao","year":"2016","unstructured":"Zhao X, Li J, Shi L et al (2016) Surgical treatment of dystrophic spinal curves caused by neurofibromatosis type 1: a retrospective study of 26 patients. Medicine (Baltimore) 95(14):e3292. https:\/\/doi.org\/10.1097\/MD.0000000000003292","journal-title":"Medicine (Baltimore)"},{"issue":"8","key":"422_CR24","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3941\/jrcr.v11i8.3113","volume":"11","author":"AM Chen","year":"2017","unstructured":"Chen AM, Neustadt JB, Kucera JN (2017) Rib head dislocation causing spinal canal stenosis in a child with neurofibromatosis, type 1. J Radiol Case Rep 11(8):8\u201315. https:\/\/doi.org\/10.3941\/jrcr.v11i8.3113","journal-title":"J Radiol Case Rep"},{"issue":"2","key":"422_CR25","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4103\/jcvjs.JCVJS_50_20","volume":"11","author":"P Cinnella","year":"2020","unstructured":"Cinnella P, Amico S, Rava A et al (2020) Surgical treatment of scoliosis in neurofibromatosis type I: a retrospective study on posterior-only correction with third-generation instrumentation. J Craniovert Jun Spine 11(2):104\u2013110. https:\/\/doi.org\/10.4103\/jcvjs.JCVJS_50_20","journal-title":"J Craniovert Jun Spine"},{"issue":"6","key":"422_CR26","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1177\/028418517801900614","volume":"19","author":"S Aaro","year":"1978","unstructured":"Aaro S, Dahlborn M, Svensson L (1978) Estimation of vertebral rotation in structural scoliosis by computer tomography. Acta Radiol Diagn (Stockh) 19(6):990\u2013992. https:\/\/doi.org\/10.1177\/028418517801900614","journal-title":"Acta Radiol Diagn (Stockh)"},{"issue":"11","key":"422_CR27","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1016\/j.crad.2004.04.006","volume":"59","author":"AI Tsirikos","year":"2004","unstructured":"Tsirikos AI, Ramachandran M, Lee J et al (2004) Assessment of vertebral scalloping in neurofibromatosis type 1 with plain radiography and MRI. Clin Radiol 59(11):1009\u20131017. https:\/\/doi.org\/10.1016\/j.crad.2004.04.006","journal-title":"Clin Radiol"},{"issue":"5","key":"422_CR28","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/s00776-003-0690-2","volume":"8","author":"T Asazuma","year":"2003","unstructured":"Asazuma T, Hashimoto T, Masuoka K et al (2003) Acute thoracic myelopathy after a traumatic episode in a patient with neurofibromatosis associated with sharply angular scoliosis: a case report. J Orthop Sci 8(5):721\u2013724. https:\/\/doi.org\/10.1007\/s00776-003-0690-2","journal-title":"J Orthop Sci"},{"issue":"5","key":"422_CR29","first-page":"414","volume":"48","author":"IA Mukhtar","year":"2005","unstructured":"Mukhtar IA, Letts M, Kontio K (2005) Spinal cord impingement by a displaced rib in scoliosis due to neurofibromatosis. Can J Surg 48(5):414\u2013415","journal-title":"Can J Surg"},{"issue":"1","key":"422_CR30","doi-asserted-by":"publisher","first-page":"96","DOI":"10.3171\/2016.7.PEDS16125","volume":"19","author":"A Deng","year":"2017","unstructured":"Deng A, Zhang H-Q, Tang M-X et al (2017) Posterior-only surgical correction of dystrophic scoliosis in 31 patients with neurofibromatosis Type 1 using the multiple anchor point method. J Neurosurg Pediatr 19(1):96\u2013101. https:\/\/doi.org\/10.3171\/2016.7.PEDS16125","journal-title":"J Neurosurg Pediatr"},{"issue":"4","key":"422_CR31","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.spinee.2014.10.014","volume":"15","author":"Z Wang","year":"2015","unstructured":"Wang Z, Fu C, Leng J et al (2015) Treatment of dystrophic scoliosis in neurofibromatosis Type 1 with one-stage posterior pedicle screw technique. Spine J 15(4):587\u2013595. https:\/\/doi.org\/10.1016\/j.spinee.2014.10.014","journal-title":"Spine J"},{"issue":"6","key":"422_CR32","doi-asserted-by":"publisher","first-page":"738","DOI":"10.3340\/jkns.2019.0218","volume":"63","author":"B-J Park","year":"2020","unstructured":"Park B-J, Hyun S-J, Wui S-H et al (2020) Surgical outcomes and complications following all posterior approach for spinal deformity associated with neurofibromatosis type-1. J Korean Neurosurg Soc 63(6):738\u2013746. https:\/\/doi.org\/10.3340\/jkns.2019.0218","journal-title":"J Korean Neurosurg Soc"},{"key":"422_CR33","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0000000000001069","author":"F Jia","year":"2020","unstructured":"Jia F, Wang G, Sun J et al (2020) Combined anterior-posterior versus posterior-only spinal fusion in treating dystrophic neurofibromatosis scoliosis with modern instrumentation: a systematic review and meta-analysis. Clin Spine Surg. https:\/\/doi.org\/10.1097\/BSD.0000000000001069","journal-title":"Clin Spine Surg."},{"key":"422_CR34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and metaanalyses: the PRISMA statement. PLoS Med. https:\/\/doi.org\/10.1371\/journal.pmed.1000097","journal-title":"PLoS Med"}],"container-title":["Spine Deformity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43390-021-00422-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s43390-021-00422-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s43390-021-00422-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T10:00:31Z","timestamp":1644573631000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s43390-021-00422-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,27]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["422"],"URL":"https:\/\/doi.org\/10.1007\/s43390-021-00422-3","relation":{},"ISSN":["2212-134X","2212-1358"],"issn-type":[{"value":"2212-134X","type":"print"},{"value":"2212-1358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,27]]},"assertion":[{"value":"21 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the investigators of this manuscript have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The conduct of this research will be carried out in compliance with the ethical principles in accordance with the regulatory standards at the national and international level, in accordance with the Resolution of the Ministry of the Nation, the Declaration of Helsinki of the World Medical Association and all its amendments, and respecting the Good Clinical Practice Standards. The institutional electronic medical record of Hospital Italiano de Buenos Aires was used as a secondary basis. All study data has been treated with the utmost confidentiality anonymously, with restricted access only for personnel authorized for the purposes of the study in accordance with current legal regulations National Personal Data Protection Law 25.326 \/ 00 (Habeas data Law) and Law 26. 529\/09. The identity of the personal data will be kept under absolute confidentiality and anonymity, only the researchers involved and the evaluating Ethics Committee have access to them.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical considerations"}},{"value":"The patient has consented in a separate document to the public publication of his personal data.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}