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But there is lack of expert consensus on the optimal MCGR lengthening interval. EOS 24-Item Questionnaire (EOSQ) is validated for assessing health-related quality of life (HrQOL), family burden, and satisfaction. This is the first study assessing how MCGR lengthening intervals affects patient-perceived outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This is a multicentred cohort study with subjects recruited from 2012 to 2018 and followed till fusion. EOS subjects who underwent MCGR surgeries were grouped into high, medium\u00a0or low lengthening interval subgroups based on 16 and 20\u00a0week cut-offs. Repeated measure analysis was performed on EOSQ\u2019s specified 12 domains. EOSQ results were taken: before index surgery, after index surgery, and prior to definitive treatment. Demographic, clinical and radiographic data were included in model adjustment.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>133 subjects with mean follow-up of 3.5 (\u00b1\u20091.3)\u00a0years were included, with 60 males and 73 females; 45 idiopathic, 23 congenital, 38 neuromuscular, and 27 syndromic patients. Mean Cobb angle at surgery was 67\u00b0 (\u00b1\u200922\u00b0) with mean age of 8.3 (\u00b1\u20092.5)\u00a0years. Between groups, clinical and radiographic parameters were comparable. Higher EOSQ scores in medium\u00a0lengthening interval subgroup was present in fatigue (<jats:italic>p<\/jats:italic>\u2009=\u20090.019), emotion (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), and parental impact (<jats:italic>p<\/jats:italic>\u2009=\u20090.049) domains, and overall score (<jats:italic>p<\/jats:italic>\u2009=\u20090.046). Trendline contrast between subgroups were present in general health (<jats:italic>p<\/jats:italic>\u2009=\u20090.006) and physical function (<jats:italic>p<\/jats:italic>\u2009=\u20090.025) domains.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Patient-perceived outcome improvements appear similar between lengthening interval subgroups. All MCGR lengthening intervals were tolerated by patients and family, with no negative impact observed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Level of evidence<\/jats:title>\n                <jats:p>Prognostic Level III.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s43390-024-00923-x","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T06:02:00Z","timestamp":1720245720000},"page":"1841-1850","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Increased lengthening frequency does not adversely affect the EOSQ scores in magnetically controlled growing rod surgeries in 133 subjects followed to final fusion"],"prefix":"10.1007","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1712-4427","authenticated-orcid":false,"given":"Sheryl Zhi Wen","family":"Saw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1983-0958","authenticated-orcid":false,"given":"Jack Zijian","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7052-0875","authenticated-orcid":false,"given":"Jason Pui Yin","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4034-8525","authenticated-orcid":false,"given":"Kenny Yat Hong","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Pediatric Spine Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8304-0419","authenticated-orcid":false,"given":"Kenneth Man Chee","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,6]]},"reference":[{"issue":"2","key":"923_CR1","doi-asserted-by":"publisher","first-page":"478","DOI":"10.52312\/jdrs.2021.49","volume":"32","author":"OF Kilicaslan","year":"2021","unstructured":"Kilicaslan OF, Tokgoz MA, Butun S, Nabi V, Akalin S (2021) Management and results of early-onset scoliosis with dual magnetically controlled growing rods: additional preliminary results of spinal fusion surgery. 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