{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:26:59Z","timestamp":1792160819561,"version":"4.4.0"},"reference-count":77,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Spine Deform"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is used for low-grade lumbar spondylolisthesis to reduce access morbidity. However, whether this compromises construct durability versus open surgery (OS) remains uncertain. We conducted a systematic review and meta-analysis to determine whether MIS-TLIF preserves fusion and reoperation outcomes while improving perioperative outcomes compared with OS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed, Embase, and CENTRAL were searched from inception to 1 December 2025. Adult MIS-TLIF was compared with OS-TLIF. Primary outcomes were fusion, overall complications, and reoperation. Secondary outcomes were operative time, blood loss, length of stay (LOS), surgical site infection (SSI), adjacent segment disease, and patient-reported outcomes. Random-effects models were used. Risk of bias (ROBINS-I\/RoB) and certainty (GRADE) were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nineteen studies encompassing 2117 patients (MIS 948, OS 1169) were included. Fusion was equivalent (RR 1.13; 95% CI 0.74\u20131.74;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.51; I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.0%). Reoperation was similar (RR 0.72; 95% CI 0.46\u20131.14;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.13; I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.0%), with no evidence of early technical failure in MIS cohorts. MIS reduced overall complications (RR 0.75; 95% CI 0.59\u20130.95;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.02; I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.0%) and SSI (RR 0.30; 95% CI 0.14\u20130.65;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.007; I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.0%). MIS lowered blood loss (MD \u2212194.0 mL; 95% CI \u2212281.98\u2013\u2212106.04;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001; I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200997.6%) and LOS (MD\u2009\u2212\u20092.1 days; 95% CI \u22122.92\u2013\u22121.24;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001; I\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200996.3%). Pain and disability converged by 1\u20132 years. Most studies had moderate risk of bias; certainty for primary outcomes was moderate overall.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MIS-TLIF achieves comparable fusion and reoperation outcomes while reducing perioperative burden, consistent with task-contingent, tissue-sparing use in appropriately selected patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s43390-026-01508-6","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T16:37:30Z","timestamp":1784565450000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Minimally invasive versus open transforaminal lumbar interbody fusion for low grade lumbar spondylolisthesis: a systematic review and meta-analysis"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2657-8874","authenticated-orcid":false,"given":"Shaan","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6625-5706","authenticated-orcid":false,"given":"Shiva A.","family":"Nischal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Griffin W.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelette","family":"Mendonca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gargee Sree","family":"Nallanukala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5512-1729","authenticated-orcid":false,"given":"Jack","family":"Jallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0943-3406","authenticated-orcid":false,"given":"James S.","family":"Harrop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivas K.","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"1508_CR1","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1007\/s00586-023-07818-x","volume":"33","author":"K Rangwalla","year":"2024","unstructured":"Rangwalla K, Filley A, El Naga A, Gendelberg D, Baldwin A, Maziad A, Arora A, Wague A, O\u2019Donnell J, Chryssikos T, Kasir R, Shah J, Theologis A, Tan L, Mummaneni P, Alamin T, Berven SH (2024) Degenerative lumbar spondylolisthesis: review of current classifications and proposal of a novel classification system. 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