{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:12:03Z","timestamp":1786983123781,"version":"build-2736575974"},"reference-count":93,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Discov Ment Health"],"DOI":"10.1007\/s44192-025-00301-7","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T10:38:40Z","timestamp":1763462320000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hemispheric disconnection as a basis for neurodegeneration in apraxia and Alzheimer\u2019s disease"],"prefix":"10.1007","volume":"5","author":[{"given":"Marco","family":"Sanna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"301_CR1","doi-asserted-by":"publisher","unstructured":"Abi Chebel N, Gaunet F, Chavet P, Assaiante C, Bourdin C, Sarlegna F. Does visual experience influence arm proprioception and its lateralization? Evidence from passive matching performance in congenitally-blind and sighted adults. PsyArXiv; 2023. https:\/\/doi.org\/10.31234\/osf.io\/hqvxa.","DOI":"10.31234\/osf.io\/hqvxa"},{"issue":"6","key":"301_CR2","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1080\/13554794.2013.826683","volume":"20","author":"LM Acosta","year":"2014","unstructured":"Acosta LM, Bennett JA, Heilman KM. Callosal disconnection and limb-kinetic apraxia. Neurocase. 2014;20(6):599\u2013605. https:\/\/doi.org\/10.1080\/13554794.2013.826683.","journal-title":"Neurocase"},{"key":"301_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-3-030-99550-8_14","volume-title":"Handbook of the cerebellum and cerebellar disorders","author":"M Adamaszek","year":"2022","unstructured":"Adamaszek M, S\u00f6r\u00f6s P, D\u2019Agata F. The cerebellum and creativity: clinical and experimental insights. In: Manto M, editor. Handbook of the cerebellum and cerebellar disorders. Springer; 2022. p. 1\u201324. https:\/\/doi.org\/10.1007\/978-3-030-99550-8_14."},{"key":"301_CR4","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.neurobiolaging.2024.03.008","volume":"137","author":"A Albadawi","year":"2024","unstructured":"Albadawi A. Neurodegenerative trajectories and callosal vulnerability in Alzheimer\u2019s disease: A microstructural DTI study. Neurobiol Aging. 2024;137:130\u201342. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2024.03.008.","journal-title":"Neurobiol Aging"},{"key":"301_CR5","doi-asserted-by":"publisher","DOI":"10.4236\/aad.2021.101001","author":"E Aligizakis","year":"2021","unstructured":"Aligizakis E, Sivaropoulos N, Gryllaki N. Alzheimer disease and music-therapy: an interesting therapeutic challenge and proposal. Adv Alzheimer\u2019s Dis. 2021. https:\/\/doi.org\/10.4236\/aad.2021.101001.","journal-title":"Adv Alzheimer's Dis"},{"key":"301_CR6","volume-title":"The birth of intersubjectivity: psychodynamics, neurobiology, and the self","author":"M Ammaniti","year":"2019","unstructured":"Ammaniti M, Gallese V. The birth of intersubjectivity: psychodynamics, neurobiology, and the self. Norton & Company; 2019."},{"key":"301_CR7","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1097\/01.ede.0000152116.32580.24","volume":"16","author":"K Andersen","year":"2005","unstructured":"Andersen K, Lolk A, Kragh-S\u00f8rensen P, Petersen N, Green A. Depression and the risk of Alzheimer disease. Epidemiology. 2005;16:233\u20138. https:\/\/doi.org\/10.1097\/01.ede.0000152116.32580.24.","journal-title":"Epidemiology"},{"issue":"1\u20133","key":"301_CR8","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.jphysparis.2008.03.001","volume":"102","author":"MA Arbib","year":"2008","unstructured":"Arbib MA. From grasp to language: Embodied concepts and the challenge of abstraction. J Physiol. 2008;102(1\u20133):4\u201320. https:\/\/doi.org\/10.1016\/j.jphysparis.2008.03.001.","journal-title":"J Physiol"},{"key":"301_CR9","doi-asserted-by":"publisher","DOI":"10.1075\/ais.12.01arb","volume-title":"Pantomime within and beyond the evolution of language","author":"MA Arbib","year":"2024","unstructured":"Arbib MA. Pantomime within and beyond the evolution of language. Amsterdam: John Benjamins Publishing Company; 2024. https:\/\/doi.org\/10.1075\/ais.12.01arb."},{"key":"301_CR10","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00103","author":"A Ardila","year":"2016","unstructured":"Ardila A. The evolutionary concept of \u201cpreadaptation\u201d applied to cognitive neurosciences. Front Neurosci Soc Evol Neurol. 2016. https:\/\/doi.org\/10.3389\/fnins.2016.00103.","journal-title":"Front Neurosci Soc Evol Neurol"},{"key":"301_CR11","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1159\/000366081","volume":"48","author":"S Arnfred","year":"2014","unstructured":"Arnfred S, Raballo A, M\u00f8rup M, Parnas J. Self-disorder and brain processing of proprioception in schizophrenia spectrum patients: a re-analysis. Psychopathology. 2014;48:60\u20134. https:\/\/doi.org\/10.1159\/000366081.","journal-title":"Psychopathology"},{"issue":"1","key":"301_CR12","doi-asserted-by":"publisher","first-page":"183","DOI":"10.3233\/JAD-2010-100177","volume":"22","author":"R Bajo","year":"2010","unstructured":"Bajo R, Maest\u00fa F, Nevado \u00c1, Sancho M, Guti\u00e9rrez R, Campo P, et al. Functional connectivity in mild cognitive impairment during a memory task: implications for the disconnection hypothesis. J Alzheimer\u2019s Dis JAD. 2010;22(1):183\u201393. https:\/\/doi.org\/10.3233\/JAD-2010-100177.","journal-title":"J Alzheimer's Dis JAD"},{"issue":"11","key":"301_CR13","doi-asserted-by":"publisher","first-page":"2666","DOI":"10.1152\/jn.00702.2012","volume":"109","author":"NH Bhanpuri","year":"2013","unstructured":"Bhanpuri NH, Okamura AM, Bastian AJ. Predictive control of movement in humans: The role of the cerebellum. J Neurophysiol. 2013;109(11):2666\u201371. https:\/\/doi.org\/10.1152\/jn.00702.2012.","journal-title":"J Neurophysiol"},{"key":"301_CR14","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.cortex.2020.11.010","volume":"135","author":"A Bartolo","year":"2021","unstructured":"Bartolo A, Cubelli R, Dalla Barba G. Ideomotor and ideational apraxia in Alzheimer\u2019s disease. Cortex. 2021;135:240\u201352. https:\/\/doi.org\/10.1016\/j.cortex.2020.11.010.","journal-title":"Cortex"},{"issue":"20","key":"301_CR15","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1016\/j.cub.2014.07.037","volume":"24","author":"RA Barton","year":"2014","unstructured":"Barton RA, Venditti C. Rapid evolution of the cerebellum in humans and other great apes. Curr Biol. 2014;24(20):2440\u20134. https:\/\/doi.org\/10.1016\/j.cub.2014.07.037.","journal-title":"Curr Biol"},{"issue":"1","key":"301_CR16","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1080\/13825585.2019.1674773","volume":"42","author":"J Baumard","year":"2020","unstructured":"Baumard J, Lesourd M, Remigereau C. Imitation of meaningless gestures in normal aging. J Clin Exp Neuropsychol. 2020;42(1):68\u201379. https:\/\/doi.org\/10.1080\/13825585.2019.1674773.","journal-title":"J Clin Exp Neuropsychol"},{"key":"301_CR17","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.cortex.2021.06.014","volume":"142","author":"J Baumard","year":"2021","unstructured":"Baumard J, Le Gall D. Cognitive mechanisms of apraxia: a comprehensive review. Cortex. 2021;142:140\u201357. https:\/\/doi.org\/10.1016\/j.cortex.2021.06.014.","journal-title":"Cortex"},{"key":"301_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2023.108519","volume":"182","author":"J Baumard","year":"2023","unstructured":"Baumard J, Caclin A, Souchay C. The role of semantic memory in tool use and apraxia. Neuropsychologia. 2023;182:108519. https:\/\/doi.org\/10.1016\/j.neuropsychologia.2023.108519.","journal-title":"Neuropsychologia"},{"key":"301_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2023.108525","volume":"183","author":"N Baumard","year":"2023","unstructured":"Baumard N, Lesourd M. Gesture, cognition, and symbolic action in neurodegenerative conditions. Neuropsychologia. 2023;183:108525. https:\/\/doi.org\/10.1016\/j.neuropsychologia.2023.108525.","journal-title":"Neuropsychologia"},{"key":"301_CR20","unstructured":"Barddakan M. Investigation into the cognitive underpinnings of apraxia: Insights from motor working memory and pantomiming object use (Ph,D Thesis , Universit\u00e4t zu K\u00f6ln); 2024. Retrieved from https:\/\/kups.ub.uni-koeln.de\/73275\/."},{"key":"301_CR21","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2015.00248","author":"E Ben-Shabat","year":"2015","unstructured":"Ben-Shabat E, Matyas T, Pell G, Brodtmann A, Carey L. The right supramarginal gyrus is important for proprioception in healthy and stroke-affected participants: a functional MRI study. Front Neurol. 2015. https:\/\/doi.org\/10.3389\/fneur.2015.00248.","journal-title":"Front Neurol"},{"key":"301_CR22","doi-asserted-by":"publisher","first-page":"14301","DOI":"10.1523\/JNEUROSCI.0784-13.2013","volume":"33","author":"N Bhanpuri","year":"2013","unstructured":"Bhanpuri N, Okamura A, Bastian A. Predictive modeling by the cerebellum improves proprioception. J Neurosci. 2013;33:14301\u20136. https:\/\/doi.org\/10.1523\/JNEUROSCI.0784-13.2013.","journal-title":"J Neurosci"},{"key":"301_CR23","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2014.00212","author":"M Boisgontier","year":"2014","unstructured":"Boisgontier M, Swinnen S. Proprioception in the cerebellum. Front Hum Neurosci. 2014. https:\/\/doi.org\/10.3389\/fnhum.2014.00212.","journal-title":"Front Hum Neurosci"},{"key":"301_CR24","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-230305","author":"A Boulares","year":"2023","unstructured":"Boulares A, Fabre C, Cherni A, Jdidi H. Incorporates exercises targeting balance, strength, and proprioception on cognitive functions and physical performance in old adults with mild cognitive impairment. J Alzheimer\u2019s Dis. 2023. https:\/\/doi.org\/10.3233\/JAD-230305.","journal-title":"J Alzheimer's Dis"},{"key":"301_CR25","doi-asserted-by":"publisher","DOI":"10.1177\/15333175221082834","author":"A Chaudhary","year":"2022","unstructured":"Chaudhary A, Sheikh S, Khemani P, Yusuf H. Apathy and emotional processing in Alzheimer\u2019s disease: Neurocognitive mechanisms and clinical implications. Am J Alzheimer\u2019s Dis Other Dementias. 2022. https:\/\/doi.org\/10.1177\/15333175221082834.","journal-title":"Am J Alzheimer's Dis Other Dementias"},{"key":"301_CR26","doi-asserted-by":"publisher","unstructured":"Chernigovskaja T. Biology, environment, and culture: from animal communication to human language and cognition. 2020;36:157\u2013170. https:\/\/doi.org\/10.21638\/spbu17.2020.113.","DOI":"10.21638\/spbu17.2020.113"},{"key":"301_CR27","doi-asserted-by":"publisher","unstructured":"Chernigovskaya T. \u201cNoise\u201d as a key to semiosis: the brain and culture (40 years later). Slovo.ru: Baltic accent; 2022. https:\/\/doi.org\/10.5922\/2225-5346-2022-2-1.","DOI":"10.5922\/2225-5346-2022-2-1"},{"issue":"3","key":"301_CR28","doi-asserted-by":"publisher","first-page":"739","DOI":"10.3233\/JAD-140324","volume":"42","author":"S Chi","year":"2014","unstructured":"Chi S, Yu J, Tan M, Tan L. Depression in Alzheimer\u2019s disease: epidemiology, mechanisms, and management. J Alzheimer\u2019s Dis JAD. 2014;42(3):739\u201355. https:\/\/doi.org\/10.3233\/JAD-140324.","journal-title":"J Alzheimer's Dis JAD"},{"key":"301_CR29","doi-asserted-by":"publisher","first-page":"e67600","DOI":"10.7554\/eLife.67600","volume":"10","author":"L Cheng","year":"2021","unstructured":"Cheng L, et al. Connectional asymmetry of the inferior parietal lobule shapes hemispheric specialization in humans, chimpanzees, and rhesus macaques. Elife. 2021;10:e67600.","journal-title":"Elife"},{"key":"301_CR30","doi-asserted-by":"publisher","first-page":"404","DOI":"10.3389\/fpsyg.2013.00404","volume":"4","author":"F Cignetti","year":"2013","unstructured":"Cignetti F, Vaugoyeau M, Assaiante C. Proprioceptive contribution to the perception of one\u2019s own body and space. Front Psychol. 2013;4:404. https:\/\/doi.org\/10.3389\/fpsyg.2013.00404.","journal-title":"Front Psychol"},{"issue":"1","key":"301_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/13803395.2016.11803","volume":"39","author":"AM Cimino-Knight","year":"2017","unstructured":"Cimino-Knight AM, Gonzalez Rothi LJ, He Y, Heilman KM. Callosal ideomotor apraxia in Alzheimer disease. J Clin Exp Neuropsychol. 2017;39(1):1\u20138. https:\/\/doi.org\/10.1080\/13803395.2016.11803.","journal-title":"J Clin Exp Neuropsychol"},{"issue":"1","key":"301_CR32","doi-asserted-by":"publisher","first-page":"13582","DOI":"10.1038\/s41598-023-42959-2","volume":"13","author":"N Corriveau-Lecavalier","year":"2024","unstructured":"Corriveau-Lecavalier N, Mellah S, Mahgoub N, Brambati SM, Belleville S. Narrative discourse in healthy aging and Alzheimer\u2019s disease: a review of default mode network function. Sci Rep. 2024;13(1):13582. https:\/\/doi.org\/10.1038\/s41598-023-42959-2.","journal-title":"Sci Rep"},{"key":"301_CR33","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1016\/j.jad.2020.12.092","volume":"282","author":"J Dunne","year":"2021","unstructured":"Dunne J, Flores M, Gawande R, Schuman-Olivier Z. Losing trust in body sensations: Interoceptive awareness and depression symptom severity among primary care patients. J Affect Disord. 2021;282:1210\u20139. https:\/\/doi.org\/10.1016\/j.jad.2020.12.092.","journal-title":"J Affect Disord"},{"key":"301_CR34","doi-asserted-by":"publisher","first-page":"1137745","DOI":"10.3389\/fpsyg.2023.1137745","volume":"14","author":"C Dzwiza-Ohlsen","year":"2023","unstructured":"Dzwiza-Ohlsen C, Kempermann G. Movement, memory, and meaning: An interdisciplinary model for the embodied self in dementia. Front Psychol. 2023;14:1137745. https:\/\/doi.org\/10.3389\/fpsyg.2023.1137745.","journal-title":"Front Psychol"},{"issue":"3","key":"301_CR35","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3390\/bs8030030","volume":"8","author":"MC Fastame","year":"2018","unstructured":"Fastame MC, Hitchcott PK, Mulas I, Ruiu M, Penna MP. Resilience in elders of the sardinian blue zone: an explorative study. Behav Sci. 2018;8(3):30. https:\/\/doi.org\/10.3390\/bs8030030.","journal-title":"Behav Sci"},{"issue":"2","key":"301_CR36","doi-asserted-by":"publisher","first-page":"162","DOI":"10.3390\/brainsci15020162","volume":"15","author":"V Florio","year":"2025","unstructured":"Florio V. Motor imagery and embodied cognition: a cortical integration perspective. Brain Sci. 2025;15(2):162.","journal-title":"Brain Sci"},{"key":"301_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhevol.2023.103505","volume":"160","author":"D Fragaszy","year":"2024","unstructured":"Fragaszy D, Kelty-Stephen D. Laterality and tool use: how early bipedalism shaped functional asymmetry. J Hum Evol. 2024;160:103505. https:\/\/doi.org\/10.1016\/j.jhevol.2023.103505.","journal-title":"J Hum Evol"},{"key":"301_CR38","doi-asserted-by":"publisher","first-page":"713","DOI":"10.2147\/NDT.S193645","volume":"15","author":"N Fujimoto","year":"2019","unstructured":"Fujimoto N, Nakamura H, Tsuda T, Wakutani Y, Takao T. Impaired comprehension of metaphorical expressions in very mild Alzheimer\u2019s disease. Neuropsychiatr Dis Treat. 2019;15:713\u201320. https:\/\/doi.org\/10.2147\/NDT.S193645.","journal-title":"Neuropsychiatr Dis Treat"},{"key":"301_CR39","doi-asserted-by":"publisher","DOI":"10.1093\/0199271941.001.0001","volume-title":"How the Body Shapes the Mind","author":"S Gallagher","year":"2005","unstructured":"Gallagher S. How the Body Shapes the Mind. Oxford University Press; 2005. https:\/\/doi.org\/10.1093\/0199271941.001.0001."},{"key":"301_CR40","doi-asserted-by":"publisher","DOI":"10.1017\/9781009209793","volume-title":"Embodied and enactive approaches to cognition","author":"S Gallagher","year":"2023","unstructured":"Gallagher S. Embodied and enactive approaches to cognition. Cambridge University Press; 2023. https:\/\/doi.org\/10.1017\/9781009209793."},{"issue":"11","key":"301_CR41","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/j.tics.2011.09.003","volume":"15","author":"V Gallese","year":"2011","unstructured":"Gallese V, Sinigaglia C. What is so special about embodied simulation? Trends Cogn Sci. 2011;15(11):512\u20139. https:\/\/doi.org\/10.1016\/j.tics.2011.09.003.","journal-title":"Trends Cogn Sci"},{"issue":"2","key":"301_CR42","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2478\/gth-2019-0010","volume":"41","author":"V Gallese","year":"2019","unstructured":"Gallese V. Embodied simulation. Its bearing on aesthetic experience and the dialogue between neuroscience and the humanities. Gestalt Theory. 2019;41(2):113\u201327. https:\/\/doi.org\/10.2478\/gth-2019-0010.","journal-title":"Gestalt Theory"},{"key":"301_CR43","first-page":"1","volume":"30","author":"V Gallese","year":"2018","unstructured":"Gallese V, Cuccio V. The neural exploitation hypothesis and its implications for an embodied approach to language and cognition: Insights from the study of action verbs processing and motor disorders in Parkinson\u2019s disease. Cortex. 2018;30:1\u201311.","journal-title":"Cortex"},{"issue":"7","key":"301_CR44","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1093\/brain\/123.7.1293","volume":"123","author":"MS Gazzaniga","year":"2000","unstructured":"Gazzaniga MS. Cerebral specialization and interhemispheric communication: Does the corpus callosum enable the human condition? Brain. 2000;123(7):1293\u2013326. https:\/\/doi.org\/10.1093\/brain\/123.7.1293.","journal-title":"Brain"},{"key":"301_CR45","volume-title":"Cognitive neuroscience: the biology of the mind","author":"MS Gazzaniga","year":"2019","unstructured":"Gazzaniga MS, Ivry RB, Mangun GR. Cognitive neuroscience: the biology of the mind. 5th ed. W. W. Norton & Company; 2019.","edition":"5"},{"key":"301_CR46","volume-title":"La parole litt\u00e9raire","author":"J Geninasca","year":"2008","unstructured":"Geninasca J. La parole litt\u00e9raire. Paris: \u00c9ditions du Seuil; 2008."},{"issue":"5","key":"301_CR47","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1002\/wcs.1241","volume":"4","author":"G Goldenberg","year":"2013","unstructured":"Goldenberg G. Apraxia. Wiley Interdiscip Rev Cognit Sci. 2013;4(5):453\u201362. https:\/\/doi.org\/10.1002\/wcs.1241.","journal-title":"Wiley Interdiscip Rev Cognit Sci"},{"key":"301_CR48","unstructured":"Greimas AJ. Du sens II: Essais s\u00e9miotiques (1re \u00e9d. [Broch\u00e9]). Paris, France: Seuil; 2012 ISBN\u202f978\u20112\u201102\u2011108116\u20119"},{"key":"301_CR49","volume-title":"S\u00e9miotique des passions: Des \u00e9tats de choses aux \u00e9tats d'\u00e2me","author":"AJ Greimas","year":"1991","unstructured":"Greimas AJ, Fontanille J. S\u00e9miotique des passions: Des \u00e9tats de choses aux \u00e9tats d\u2019\u00e2me. Gallimard Paris; 1991."},{"key":"301_CR50","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.3389\/fpsyg.2014.01228","volume":"5","author":"M Grist","year":"2021","unstructured":"Grist M, Scanlon T. Gestural and symbolic development among apes and humans: implications for cultural evolution. Front Psychol. 2021;5:1228. https:\/\/doi.org\/10.3389\/fpsyg.2014.01228.","journal-title":"Front Psychol"},{"key":"301_CR51","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.cortex.2017.08.019","volume":"100","author":"X Guell","year":"2018","unstructured":"Guell X, Gabrieli JDE, Schmahmann JD. Embodied cognition and the cerebellum: Perspectives from the dysmetria of thought and the universal cerebellar transform theories. Cortex. 2018;100:140\u20138. https:\/\/doi.org\/10.1016\/j.cortex.2017.08.019.","journal-title":"Cortex"},{"key":"301_CR52","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.842221","volume":"14","author":"R Kumar","year":"2022","unstructured":"Kumar R, Yadav P, Sharma A. Corpus callosum integrity and interhemispheric disconnection in early Alzheimer\u2019s disease: a DTI study. Front Aging Neurosci. 2022;14:842221. https:\/\/doi.org\/10.3389\/fnagi.2022.842221.","journal-title":"Front Aging Neurosci"},{"key":"301_CR53","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.576120","volume":"11","author":"AM Ladda","year":"2020","unstructured":"Ladda AM, Eggert T, Glasauer S, Straube A. The parietal cortex and its role in higher-order motor control and learning: Evidence from dancer and musician training. Front Psychol. 2020;11:576120. https:\/\/doi.org\/10.3389\/fpsyg.2020.576120.","journal-title":"Front Psychol"},{"issue":"4","key":"301_CR54","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.3233\/JAD-150725","volume":"50","author":"M Lacalle-Aurioles","year":"2016","unstructured":"Lacalle-Aurioles M, Alem\u00e1n-G\u00f3mez Y, Delgado-Alvarado M. Structural disconnection in Alzheimer\u2019s disease: Multimodal MRI analysis of corpus callosum integrity and its relationship with clinical symptoms. J Alzheimers Dis. 2016;50(4):1109\u201321. https:\/\/doi.org\/10.3233\/JAD-150725.","journal-title":"J Alzheimers Dis"},{"key":"301_CR55","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/978-3-030-99550-8_16","volume-title":"Embodied Emotions and Psychological Traits","author":"D Laricchiuta","year":"2022","unstructured":"Laricchiuta D, Picerni E, Cutuli D, Petrosini L. Cerebellum, embodied emotions, and psychological traits. In: Embodied Emotions and Psychological Traits. Springer; 2022. p. 257\u201375. https:\/\/doi.org\/10.1007\/978-3-030-99550-8_16."},{"key":"301_CR56","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.neubiorev.2019.05.016","volume":"102","author":"M Lesourd","year":"2019","unstructured":"Lesourd M, Baumard J, Osiurak F. From ideation to execution: A neurocognitive framework of apraxia. Neurosci Biobehav Rev. 2019;102:316\u201325. https:\/\/doi.org\/10.1016\/j.neubiorev.2019.05.016.","journal-title":"Neurosci Biobehav Rev"},{"key":"301_CR57","doi-asserted-by":"publisher","DOI":"10.7551\/mitpress\/15233.001.0001","volume-title":"The invisible hand: neurocognitive mechanisms of human hand function","author":"MR Longo","year":"2025","unstructured":"Longo MR. The invisible hand: neurocognitive mechanisms of human hand function. MIT Press; 2025. https:\/\/doi.org\/10.7551\/mitpress\/15233.001.0001."},{"key":"301_CR58","unstructured":"Lotman YM. Kul\u2019ture kak collektiv intellekt I problemy iskussiven nogo razuma (Prevaritel\u2019naia Publikacija), Akademija nauk SSSR Nau\u010dnyj sovet po kompleksno probleme \u201ckibernetika\u201d, Moskva 1977; 1977. p. 1\u201318. Culture as collective intellect and problems of artificial intelligence Translated by Ann Shukman (only link): https:\/\/monoskop.org\/File:Lotman_Yuri_1979_Culture_as_Collective_Intellect_and_the_Problems_of_Artificial_Intelligence.pdf."},{"key":"301_CR59","doi-asserted-by":"crossref","unstructured":"Lotman YM. Universe of Mind. A Semiotic Theory of Culture, Bloomington-Indianapolis: Indiana University Press [1990 Tauris Press London]; 2001.","DOI":"10.2979\/3231.0"},{"issue":"1","key":"301_CR60","doi-asserted-by":"publisher","first-page":"205","DOI":"10.12697\/SSS.2005.33.1.09","volume":"33","author":"YM Lotman","year":"2005","unstructured":"Lotman YM, Clark J. On the semiosphere. Sign Systems Studies. 2005;33(1):205\u201329. https:\/\/doi.org\/10.12697\/SSS.2005.33.1.09.","journal-title":"Sign Systems Studies"},{"issue":"1","key":"301_CR61","doi-asserted-by":"publisher","first-page":"12","DOI":"10.31249\/metodquarterly\/02.01.02","volume":"2","author":"YM Lotman","year":"2022","unstructured":"Lotman YM. Talk at Tartu State University, March 13, 1981. METHOD Moscow Quart J Soc Stud. 2022;2(1):12\u201327. https:\/\/doi.org\/10.31249\/metodquarterly\/02.01.02.","journal-title":"METHOD Moscow Quart J Soc Stud"},{"key":"301_CR62","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2024.119827","volume":"293","author":"M Lotze","year":"2024","unstructured":"Lotze M. Neural correlates of emotional embodiment: Evidence from insular lesions. Neuroimage. 2024;293:119827. https:\/\/doi.org\/10.1016\/j.neuroimage.2024.119827.","journal-title":"Neuroimage"},{"issue":"4","key":"301_CR63","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3390\/vision8040058","volume":"8","author":"RR MacNeil","year":"2024","unstructured":"MacNeil RR, Enns JT. The \u201cWhat\u201d and \u201cHow\u201d of pantomime actions. Vision. 2024;8(4):58. https:\/\/doi.org\/10.3390\/vision8040058.","journal-title":"Vision"},{"issue":"9","key":"301_CR64","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1093\/CERCOR\/13.9.962","volume":"13","author":"P MacDonald","year":"2003","unstructured":"MacDonald P, Paus T. The role of parietal cortex in awareness of self-generated movements: a transcranial magnetic stimulation study. Cereb Cortex. 2003;13(9):962\u20137. https:\/\/doi.org\/10.1093\/CERCOR\/13.9.962.","journal-title":"Cereb Cortex"},{"issue":"2","key":"301_CR65","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.tics.2003.12.008","volume":"8","author":"A Maravita","year":"2004","unstructured":"Maravita A, Iriki A. Tools for the body (schema). Trends Cogn Sci. 2004;8(2):79\u201386. https:\/\/doi.org\/10.1016\/j.tics.2003.12.008.","journal-title":"Trends Cogn Sci"},{"key":"301_CR66","volume-title":"Ph\u00e9nom\u00e9nologie de la perception","author":"M Merleau-Ponty","year":"1945","unstructured":"Merleau-Ponty M. Ph\u00e9nom\u00e9nologie de la perception. Paris: Gallimard; 1945."},{"key":"301_CR67","doi-asserted-by":"publisher","unstructured":"Merleau\u2011Ponty M. Phenomenology of perception (D.\u202fA.\u202fLandes, Trans.; 1st ed.). Routledge; 2012. https:\/\/doi.org\/10.4324\/9780203720714.","DOI":"10.4324\/9780203720714"},{"key":"301_CR68","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-021-01155-6","author":"DC Mograbi","year":"2021","unstructured":"Mograbi DC, Huntley J, Critchley H. Self-awareness in dementia: A taxonomy of processes, overview of findings, and integrative framework. Curr Neurol Neurosci Rep. 2021. https:\/\/doi.org\/10.1007\/s11910-021-01155-6.","journal-title":"Curr Neurol Neurosci Rep"},{"key":"301_CR69","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1159\/000356343","volume":"71","author":"Y Moon","year":"2014","unstructured":"Moon Y, Moon W, Kim H, Han S. Regional Atrophy of the Insular Cortex Is Associated with Neuropsychiatric Symptoms in Alzheimer\u2019s Disease Patients. Eur Neurol. 2014;71:223\u20139. https:\/\/doi.org\/10.1159\/000356343.","journal-title":"Eur Neurol"},{"key":"301_CR70","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.neures.2015.10.013","volume":"104","author":"E Naito","year":"2016","unstructured":"Naito E, Morita T, Amemiya K. Body representations in the human brain revealed by kinesthetic illusions and their essential contributions to motor control and corporeal awareness. Neurosci Res. 2016;104:16\u201330. https:\/\/doi.org\/10.1016\/j.neures.2015.10.013.","journal-title":"Neurosci Res"},{"issue":"2","key":"301_CR71","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1080\/23279095.2021.1890595","volume":"32","author":"A Naro","year":"2022","unstructured":"Naro A, Bramanti P, Leo A, Russo M, Manuli A, Calabr\u00f2 RS. Embodied cognition in neurological disorders: rehabilitative implications and clinical evidence. Neuropsychol Rehabil. 2022;32(2):220\u201341. https:\/\/doi.org\/10.1080\/23279095.2021.1890595.","journal-title":"Neuropsychol Rehabil"},{"issue":"6","key":"301_CR72","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.3758\/s13423-016-1052-3","volume":"23","author":"F Osiurak","year":"2016","unstructured":"Osiurak F, Badets A. Tool use and affordance: a synthesis. Psychon Bull Rev. 2016;23(6):1585\u2013606. https:\/\/doi.org\/10.3758\/s13423-016-1052-3.","journal-title":"Psychon Bull Rev"},{"key":"301_CR73","doi-asserted-by":"publisher","first-page":"1996","DOI":"10.3390\/ani11071996","volume":"11","author":"LJ Rogers","year":"2021","unstructured":"Rogers LJ. Brain lateralization and cognitive capacity. Animals. 2021;11:1996. https:\/\/doi.org\/10.3390\/ani11071996.","journal-title":"Animals"},{"key":"301_CR74","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1007\/s40520-021-02068-7","volume":"34","author":"M Ruiu","year":"2022","unstructured":"Ruiu M, Carta V, Deiana C, et al. Is the Sardinian Blue Zone the New Shangri-La for mental health? Evidence on depressive symptoms and its correlates in late adult life span. Aging Clin Exp Res. 2022;34:1315\u201322. https:\/\/doi.org\/10.1007\/s40520-021-02068-7.","journal-title":"Aging Clin Exp Res"},{"key":"301_CR75","unstructured":"Perciballi C. Hands as tools: how manual behavior shapes actions and spontaneous and task-evoked brain activity (Doctoral dissertation, Sapienza Universit\u00e0 di Roma); 2025. https:\/\/tesidottorato.depositolegale.it\/handle\/20.500.14242\/189706."},{"issue":"5","key":"301_CR76","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1007\/s40519-019-00780-y","volume":"25","author":"GM Pes","year":"2020","unstructured":"Pes GM, Loriga S, Errigo A, Tedde P, Dore MP. Is mini-nutritional assessment a reliable tool in detecting malnutrition in elderly with body weight excess? Eat Weight Disord. 2020;25(5):1425\u201335. https:\/\/doi.org\/10.1007\/s40519-019-00780-y.","journal-title":"Eat Weight Disord"},{"key":"301_CR77","doi-asserted-by":"publisher","DOI":"10.1177\/10738584221120187","author":"L Petrosini","year":"2024","unstructured":"Petrosini L, Picerni E, Termine A. The cerebellum as an embodying machine. Neuroscientist. 2024. https:\/\/doi.org\/10.1177\/10738584221120187.","journal-title":"Neuroscientist"},{"issue":"4","key":"301_CR78","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1152\/physrev.00048.2011","volume":"92","author":"U Proske","year":"2012","unstructured":"Proske U, Gandevia S. The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiol Rev. 2012;92(4):1651\u201397. https:\/\/doi.org\/10.1152\/physrev.00048.2011.","journal-title":"Physiol Rev"},{"issue":"7","key":"301_CR79","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158840","volume":"11","author":"T Qiu","year":"2016","unstructured":"Qiu T, Wang Y, Liu Q, Zhou J, Zhang Y, Yu C, et al. Disrupted interhemispheric coordination in Alzheimer\u2019s disease: a resting-state functional MRI study. PLoS ONE. 2016;11(7):e0158840. https:\/\/doi.org\/10.1371\/journal.pone.0158840.","journal-title":"PLoS ONE"},{"key":"301_CR80","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2014.00973","author":"C Roncero","year":"2014","unstructured":"Roncero C, Almeida R. The importance of being apt: metaphor comprehension in Alzheimer\u2019s disease. Front Hum Neurosci. 2014. https:\/\/doi.org\/10.3389\/fnhum.2014.00973.","journal-title":"Front Hum Neurosci"},{"issue":"5","key":"301_CR81","doi-asserted-by":"publisher","first-page":"2408","DOI":"10.1152\/jn.00901.2001","volume":"88","author":"RL Sainburg","year":"2000","unstructured":"Sainburg RL, Kalakanis D. Differences in intersegmental dynamics between dominant and non-dominant arms. J Neurophysiol. 2000;88(5):2408\u201321. https:\/\/doi.org\/10.1152\/jn.00901.2001.","journal-title":"J Neurophysiol"},{"issue":"7","key":"301_CR82","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1167\/13.7.2","volume":"13","author":"R Salomon","year":"2013","unstructured":"Salomon R, Lim M, Herbelin B, Hesselmann G, Blanke O. Posing for awareness: proprioception modulates access to visual consciousness in a continuous flash suppression task. J Vis. 2013;13(7):2. https:\/\/doi.org\/10.1167\/13.7.2.","journal-title":"J Vis"},{"issue":"2","key":"301_CR83","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3390\/neurosci6020042","volume":"6","author":"M Sanna","year":"2025","unstructured":"Sanna M. Proprioceptive resonance and multimodal semiotics: readiness to act, embodied cognition, and the dynamics of meaning. NeuroSci. 2025;6(2):42. https:\/\/doi.org\/10.3390\/neurosci6020042.","journal-title":"NeuroSci"},{"issue":"1","key":"301_CR84","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s00429-022-02598-7","volume":"229","author":"E Sanz-Morales","year":"2024","unstructured":"Sanz-Morales E, Melero H. Disruption of embodied simulation and self-processing mechanisms in Alzheimer\u2019s disease: The role of the inferior parietal lobule. Brain Struct Funct. 2024;229(1):223\u201341. https:\/\/doi.org\/10.1007\/s00429-022-02598-7.","journal-title":"Brain Struct Funct"},{"issue":"4","key":"301_CR85","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1177\/0305735605056155","volume":"33","author":"JA Seitz","year":"2005","unstructured":"Seitz JA. Dalcroze, the body, movement and musicality. Psychol Music. 2005;33(4):419\u201335. https:\/\/doi.org\/10.1177\/0305735605056155.","journal-title":"Psychol Music"},{"issue":"7","key":"301_CR86","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1038\/nrn1900","volume":"7","author":"DJ Serrien","year":"2006","unstructured":"Serrien DJ, Ivry RB, Swinnen SP. The missing link between action and cognition. Nat Rev Neurosci. 2006;7(7):492\u2013503. https:\/\/doi.org\/10.1038\/nrn1900.","journal-title":"Nat Rev Neurosci"},{"key":"301_CR87","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1038\/nrn3916","volume":"16","author":"Y Tang","year":"2015","unstructured":"Tang Y, H\u00f6lzel B, Posner M. The neuroscience of mindfulness meditation. Nat Rev Neurosci. 2015;16:213\u201325. https:\/\/doi.org\/10.1038\/nrn3916.","journal-title":"Nat Rev Neurosci"},{"issue":"3","key":"301_CR88","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1007\/s12311-020-01155-1","volume":"19","author":"F Van Overwalle","year":"2020","unstructured":"Van Overwalle F, Baetens K, Mari\u00ebn P, Vandekerckhove M. Consensus paper: cerebellum and social cognition. Cerebellum. 2020;19(3):833\u201368. https:\/\/doi.org\/10.1007\/s12311-020-01155-1.","journal-title":"Cerebellum"},{"issue":"2","key":"301_CR89","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1093\/scan\/nsab014","volume":"17","author":"F Van Overwalle","year":"2022","unstructured":"Van Overwalle F, Mari\u00ebn P. Posterior cerebellum supports prediction in social action sequences. Soc Cognit Affect Neurosci. 2022;17(2):241\u201351. https:\/\/doi.org\/10.1093\/scan\/nsab014.","journal-title":"Soc Cognit Affect Neurosci"},{"key":"301_CR90","doi-asserted-by":"publisher","DOI":"10.7551\/mitpress\/6730.001.0001","volume-title":"New ed. 2017. The embodied mind: cognitive science and human experience","author":"FJ Varela","year":"1991","unstructured":"Varela FJ, Thompson E, Rosch E. New ed. 2017. The embodied mind: cognitive science and human experience. MIT Press; 1991. https:\/\/doi.org\/10.7551\/mitpress\/6730.001.0001."},{"key":"301_CR91","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.975711","volume":"14","author":"C-C Wu","year":"2022","unstructured":"Wu C-C, Xiong H-Y, Zheng J-J, Wang X-Q. Dance movement therapy for neurodegenerative diseases: a systematic review. Front Aging Neurosci. 2022;14:975711. https:\/\/doi.org\/10.3389\/fnagi.2022.975711.","journal-title":"Front Aging Neurosci"},{"key":"301_CR92","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2017.00261","author":"C Yang","year":"2017","unstructured":"Yang C, Zhong S, Zhou X, Wei L, Wang L, Nie S. The abnormality of topological asymmetry between hemispheric brain white matter networks in Alzheimer\u2019s disease and mild cognitive impairment. Front Aging Neurosci. 2017. https:\/\/doi.org\/10.3389\/fnagi.2017.00261.","journal-title":"Front Aging Neurosci"},{"issue":"1","key":"301_CR93","doi-asserted-by":"publisher","first-page":"7","DOI":"10.31249\/metodquarterly\/02.01.01","volume":"2","author":"S Zolyan","year":"2022","unstructured":"Zolyan S. Preface to the publication of Yuri Lotman\u2019s talk. METHOD Moscow Quart J Soc Stud. 2022;2(1):7\u201311. https:\/\/doi.org\/10.31249\/metodquarterly\/02.01.01.","journal-title":"METHOD Moscow Quart J Soc Stud"}],"container-title":["Discover Mental Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s44192-025-00301-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s44192-025-00301-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s44192-025-00301-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T10:38:42Z","timestamp":1763462322000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s44192-025-00301-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":93,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["301"],"URL":"https:\/\/doi.org\/10.1007\/s44192-025-00301-7","relation":{},"ISSN":["2731-4383"],"issn-type":[{"value":"2731-4383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,18]]},"assertion":[{"value":"13 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"No animal studies are presented in this manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal ethics statement"}},{"value":"No studies involving human participants are presented in this manuscript.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics statement"}},{"value":"No potentially identifiable images or personal data are presented in this manuscript.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Inclusion of identifiable human data"}},{"value":"The authors declare no competing interests.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"178"}}