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The coexistence of sudden cardiac dysfunction and long-standing HTN may amplify morbidity and mortality and contribute to persistent demographic and geographic disparities. This study characterizes 2000\u20132024 national trends in CA with concurrent HTN among U.S. adults and projects age-adjusted mortality rates (AAMRs) through 2035.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of Multiple Cause-of-Death data from the CDC WONDER database for CA with HTN mortality among adults aged\u2009\u2265\u200925 years (2000\u20132024). We calculated AAMRs and used joinpoint regression to estimate annual percent changes (APCs) and the average APC (AAPC) with 95% confidence intervals (CIs). We projected AAMRs through 2035 using Auto-ARIMA and Prophet time-series models in R (v4.5.0) and evaluated model performance using the root mean squared error (RMSE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From 2000 to 2024, there were 1,693,840 deaths from CA with concurrent HTN. Overall AAMR rose from 24.56 to 31.68, with an AAPC of 0.82 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.000001). Men had higher AAMRs than women (overall AAMR: men 32.89; women 25.95). Among races, non-Hispanic (NH) Black\/African American adults had the highest mortality (AAMR: 58.25). Older adults (\u2265\u200965 years) bore the highest burden (AAMR: 122.60). Geographic differences were observed, with the West having the highest burden (AAMR: 43.75). Urban areas had higher AAMRs than rural areas (28.88 vs. 25.50). Most deaths (43.78%) occurred in medical facilities. Forecasting to 2035 indicates continued rises, particularly among men, NH Black\/African American adults, older adults, West and rural areas.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CA with concurrent HTN imposes a substantial and rising mortality burden, with pronounced demographic and geographic disparities. Continued surveillance and targeted public-health interventions are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s44197-026-00588-x","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T02:44:46Z","timestamp":1779677086000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Temporal Trends and Forecasted Cardiac Arrest and Hypertension-Related Mortality in U.S. Adults, 2000\u20132035: A Nationwide CDC WONDER Multiple Cause-of-Death Study"],"prefix":"10.1007","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6278-9971","authenticated-orcid":false,"given":"Saifullah","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FNU","family":"Arsheen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muneeb","family":"Fareed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahreem","family":"Mari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preet","family":"Memon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S M Aleem","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Naz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusra","family":"Ejaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg C.","family":"Fonarow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasibullah","family":"Aminpoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"issue":"6","key":"588_CR1","doi-asserted-by":"publisher","DOI":"10.1002\/emp2.13070","volume":"4","author":"CY Fan","year":"2023","unstructured":"Fan CY, Sung CW, Chen CY, Chen CH, Chen L, Chen YC, et al. 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