{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T19:20:58Z","timestamp":1793733658340,"version":"4.6.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Blood Res."],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s44313-025-00118-x","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T04:25:57Z","timestamp":1766550357000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Awareness and real-world practices in chronic lymphocytic leukemia: insights from a nationwide survey of Korean hematologists"],"prefix":"10.1007","volume":"61","author":[{"given":"Seungah","family":"Cha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwai Han","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EunHee","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ja Min","family":"Byun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"issue":"1","key":"118_CR1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3322\/caac.21820","volume":"74","author":"RL Siegel","year":"2024","unstructured":"Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74(1):17\u201348. https:\/\/doi.org\/10.3322\/caac.21820.","journal-title":"CA Cancer J Clin"},{"key":"118_CR2","doi-asserted-by":"publisher","first-page":"840616","DOI":"10.3389\/fonc.2022.840616","volume":"12","author":"Y Ou","year":"2022","unstructured":"Ou Y, Long Y, Ji L, Zhan Y, Qiao T, Wang X, et al. Trends in disease burden of chronic lymphocytic leukemia at the global, regional, and national levels from 1990 to 2019, and projections until 2030: a population-based epidemiologic study. Front Oncol. 2022;12:840616. https:\/\/doi.org\/10.3389\/fonc.2022.840616.","journal-title":"Front Oncol"},{"issue":"5","key":"118_CR3","doi-asserted-by":"publisher","first-page":"747","DOI":"10.3904\/kjim.2022.408","volume":"38","author":"JS Kim","year":"2023","unstructured":"Kim JS, Kim TM, Kang MJ, Koh SA, Park H, Nam SH, et al. Treatment pattern of chronic lymphocytic leukemia\/small lymphocytic lymphoma in Korea: a multicenter retrospective study (KCSG LY20-06). Korean J Intern Med. 2023;38(5):747\u201357. https:\/\/doi.org\/10.3904\/kjim.2022.408.","journal-title":"Korean J Intern Med"},{"issue":"2","key":"118_CR4","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s10147-024-02645-6","volume":"30","author":"J Yuda","year":"2025","unstructured":"Yuda J, Wang C, Terasawa T, Tajimi M, Osaga S, Miura M, et al. Treatment selection and influencing factors for chronic lymphocytic leukemia: a physician survey in Japan. Int J Clin Oncol. 2025;30(2):157\u201367. https:\/\/doi.org\/10.1007\/s10147-024-02645-6.","journal-title":"Int J Clin Oncol"},{"issue":"Suppl 1","key":"118_CR5","doi-asserted-by":"publisher","first-page":"7601","DOI":"10.1182\/blood-2024-208406","volume":"144","author":"RP Topping","year":"2024","unstructured":"Topping RP, Quill TA, Awan FT, Cohen JB. Treatment patterns and attitudes among US-based physicians in using BTK inhibitors to treat relapsed\/refractory CLL and MCL. Blood. 2024;144(Suppl 1):7601\u20132. https:\/\/doi.org\/10.1182\/blood-2024-208406.","journal-title":"Blood"},{"issue":"8","key":"118_CR6","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1182\/blood.2022018818","volume":"142","author":"JF Seymour","year":"2023","unstructured":"Seymour JF, Byrd JC, Ghia P, Kater AP, Chanan-Khan A, Furman RR, et al. Detailed safety profile of acalabrutinib vs ibrutinib in previously treated chronic lymphocytic leukemia in the ELEVATE-RR trial. Blood. 2023;142(8):687\u201399. https:\/\/doi.org\/10.1182\/blood.2022018818.","journal-title":"Blood"},{"issue":"4","key":"118_CR7","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1056\/NEJMoa2211582","volume":"388","author":"JR Brown","year":"2023","unstructured":"Brown JR, Eichhorst B, Hillmen P, Jurczak W, Ka\u017amierczak M, Lamanna N, et al. Zanubrutinib or ibrutinib in relapsed or refractory chronic lymphocytic leukemia. N Engl J Med. 2023;388(4):319\u201332. https:\/\/doi.org\/10.1056\/NEJMoa2211582.","journal-title":"N Engl J Med"},{"issue":"12","key":"118_CR8","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1056\/NEJMoa1713976","volume":"378","author":"JF Seymour","year":"2018","unstructured":"Seymour JF, Kipps TJ, Eichhorst B, Hillmen P, D\u2019Rozario J, Assouline S, et al. Venetoclax\u2013rituximab in relapsed or refractory chronic lymphocytic leukemia. N Engl J Med. 2018;378(12):1107\u201320. https:\/\/doi.org\/10.1056\/NEJMoa1713976.","journal-title":"N Engl J Med"},{"key":"118_CR9","unstructured":"National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Chronic Lymphocytic Leukemia\/Small Lymphocytic Lymphoma. Version 1.2024. Plymouth Meeting (PA): National Comprehensive Cancer Network; 2024."},{"key":"118_CR10","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.3109\/10428194.2013.869801","volume":"55","author":"MJ Conte","year":"2014","unstructured":"Conte MJ, Bowen DA, Wiseman GA, et al. Use of positron emission tomography-computed tomography in the management of patients with chronic lymphocytic leukemia\/small lymphocytic lymphoma. Leuk Lymphoma. 2014;55:2079\u201384. https:\/\/doi.org\/10.3109\/10428194.2013.869801.","journal-title":"Leuk Lymphoma"},{"key":"118_CR11","doi-asserted-by":"publisher","first-page":"2783","DOI":"10.1182\/blood-2013-11-536169","volume":"123","author":"L Falchi","year":"2014","unstructured":"Falchi L, Keating MJ, Marom EM, et al. Correlation between FDG\/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia. Blood. 2014;123:2783\u201390. https:\/\/doi.org\/10.1182\/blood-2013-11-536169.","journal-title":"Blood"},{"issue":"1","key":"118_CR12","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1002\/cncr.31738","volume":"125","author":"EK Seymour","year":"2019","unstructured":"Seymour EK, Ruterbusch JJ, Beebe-Dimmer JL, Schiffer CA. Real-world testing and treatment patterns in chronic lymphocytic leukemia: a SEER patterns of care analysis. Cancer. 2019;125(1):135\u201343. https:\/\/doi.org\/10.1002\/cncr.31738.","journal-title":"Cancer"},{"issue":"8","key":"118_CR13","doi-asserted-by":"publisher","first-page":"2895","DOI":"10.1007\/s10238-023-01007-2","volume":"23","author":"E Tse","year":"2023","unstructured":"Tse E, Kwong YL, Goh YT, Bee PC, Ng SC, Tan D, et al. Expert consensus on the management of chronic lymphocytic leukaemia in Asia. Clin Exp Med. 2023;23(8):2895\u2013907. https:\/\/doi.org\/10.1007\/s10238-023-01007-2.","journal-title":"Clin Exp Med"},{"issue":"4","key":"118_CR14","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1111\/bjh.12659","volume":"164","author":"D Chihara","year":"2014","unstructured":"Chihara D, Ito H, Matsuda T, Shibata A, Katsumi A, Nakamura S, et al. Differences in incidence and trends of haematological malignancies in Japan and the United States. Br J Haematol. 2014;164(4):536\u201345. https:\/\/doi.org\/10.1111\/bjh.12659.","journal-title":"Br J Haematol"},{"issue":"4","key":"118_CR15","doi-asserted-by":"publisher","first-page":"243","DOI":"10.5045\/br.2021.2021102","volume":"56","author":"JH Yi","year":"2021","unstructured":"Yi JH, Lee GW, Lee JH, Yoo KH, Jung CW, Kim DS, et al. Multicenter retrospective analysis of patients with chronic lymphocytic leukemia in Korea. Blood Res. 2021;56(4):243\u201351. https:\/\/doi.org\/10.5045\/br.2021.2021102.","journal-title":"Blood Res"},{"issue":"3","key":"118_CR16","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s12185-013-1286-z","volume":"97","author":"MA Jang","year":"2013","unstructured":"Jang MA, Yoo EH, Kim K, Kim WS, Jung CW, Kim SH, et al. Chronic lymphocytic leukemia in Korean patients: frequent atypical immunophenotype and relatively aggressive clinical behavior. Int J Hematol. 2013;97(3):403\u20138. https:\/\/doi.org\/10.1007\/s12185-013-1286-z.","journal-title":"Int J Hematol"}],"container-title":["Blood Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s44313-025-00118-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s44313-025-00118-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s44313-025-00118-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T12:31:53Z","timestamp":1769517113000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s44313-025-00118-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["118"],"URL":"https:\/\/doi.org\/10.1007\/s44313-025-00118-x","relation":{},"ISSN":["2287-979X","2288-0011"],"issn-type":[{"value":"2287-979X","type":"print"},{"value":"2288-0011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,24]]},"assertion":[{"value":"14 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Institutional Review Board of Seoul National University Hospital. The requirement for informed consent was waived owing to the anonymous, minimal-risk survey design. All procedures were performed in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"4"}}