{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T10:16:17Z","timestamp":1788516977282,"version":"build-2803163510"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:00:00Z","timestamp":1783728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:00:00Z","timestamp":1783728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"crossref","award":["LQ21H120007"],"award-info":[{"award-number":["LQ21H120007"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ophthalmic Physiol. Opt."],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s44402-026-00134-z","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T11:31:55Z","timestamp":1783769515000},"page":"1033-1039","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Decreasing Radial Peripapillary Capillary Perfusion Density Correlated With Visual Field Impairment in High Myopia"],"prefix":"10.1007","volume":"46","author":[{"given":"Chen","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilei","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meixiao","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,11]]},"reference":[{"key":"134_CR1","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","volume":"123","author":"BA Holden","year":"2016","unstructured":"Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, et al. Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology. 2016;123:1036\u201342. https:\/\/doi.org\/10.1016\/j.ophtha.2016.01.006.","journal-title":"Ophthalmology"},{"key":"134_CR2","doi-asserted-by":"publisher","first-page":"2800","DOI":"10.1167\/iovs.18-26085","volume":"60","author":"Y Wang","year":"2019","unstructured":"Wang Y, Ye J, Shen M, Yao A, Xue A, Fan Y, et al. Photoreceptor degeneration is correlated with the deterioration of macular retinal sensitivity in high myopia. Invest Ophthalmol Vis Sci. 2019;60:2800\u201310. https:\/\/doi.org\/10.1167\/iovs.18-26085.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"134_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.710344","volume":"15","author":"J Ye","year":"2021","unstructured":"Ye J, Sinha P, Hou F, He X, Shen M, Lu F, et al. Impact of temporal visual flicker on spatial contrast sensitivity in myopia. Front Neurosci. 2021;15:710344. https:\/\/doi.org\/10.3389\/fnins.2021.710344.","journal-title":"Front Neurosci"},{"key":"134_CR4","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1016\/S0140-6736(17)31469-1","volume":"390","author":"JB Jonas","year":"2017","unstructured":"Jonas JB, Aung T, Bourne RR, Bron AM, Ritch R, Panda-Jonas S. Glaucoma. Lancet. 2017;390:2183\u201393. https:\/\/doi.org\/10.1016\/S0140-6736(17)31469-1.","journal-title":"Lancet"},{"key":"134_CR5","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1136\/bjophthalmol-2020-318674","volume":"106","author":"C Lanca","year":"2022","unstructured":"Lanca C, Sun CH, Chong R, Wong YL, Nongpiur ME, Htoon HM, et al. Visual field defects and myopic macular degeneration in Singapore adults with high myopia. Br J Ophthalmol. 2022;106:1423\u20138. https:\/\/doi.org\/10.1136\/bjophthalmol-2020-318674.","journal-title":"Br J Ophthalmol"},{"key":"134_CR6","doi-asserted-by":"publisher","first-page":"4430.","DOI":"10.3390\/jcm11154430","volume":"11","author":"A Lee","year":"2022","unstructured":"Lee A, Shin JW, Lee JY, Baek MS, Kook MS. Association of superficial and deep macular microvasculature with central visual field sensitivity in glaucomatous eyes with high myopia. J Clin Med. 2022;11:4430. https:\/\/doi.org\/10.3390\/jcm11154430.","journal-title":"J Clin Med"},{"key":"134_CR7","doi-asserted-by":"publisher","unstructured":"Shin JW, Kwon J, Lee J, Kook MS. Relationship between vessel density and visual field sensitivity in glaucomatous eyes with high myopia. Br J Ophthalmol. 2019;103:585\u201391. https:\/\/doi.org\/10.1136\/bjophthalmol-2018-312085.","DOI":"10.1136\/bjophthalmol-2018-312085"},{"key":"134_CR8","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.ophtha.2018.07.007","volume":"126","author":"MW Lee","year":"2019","unstructured":"Lee MW, Kim JM, Shin YI, Jo YJ, Kim JY. Longitudinal changes in peripapillary retinal nerve fiber layer thickness in high myopia: a prospective, observational study. Ophthalmology. 2019;126:522\u20138. https:\/\/doi.org\/10.1016\/j.ophtha.2018.07.007.","journal-title":"Ophthalmology"},{"key":"134_CR9","doi-asserted-by":"publisher","first-page":"30.","DOI":"10.1167\/iovs.61.10.30","volume":"61","author":"HB Lim","year":"2020","unstructured":"Lim HB, Shin YI, Lee MW, Lee JU, Lee WH, Kim JY. Association of myopia with peripapillary retinal nerve fiber layer thickness in diabetic patients without diabetic retinopathy. Invest Ophthalmol Vis Sci. 2020;61:30. https:\/\/doi.org\/10.1167\/iovs.61.10.30.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"134_CR10","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.ajo.2021.03.019","volume":"229","author":"SS Swaminathan","year":"2021","unstructured":"Swaminathan SS, Jammal AA, Berchuck SI, Medeiros FA. Rapid initial OCT RNFL thinning is predictive of faster visual field loss during extended follow-up in glaucoma. Am J Ophthalmol. 2021;229:100\u20137. https:\/\/doi.org\/10.1016\/j.ajo.2021.03.019.","journal-title":"Am J Ophthalmol"},{"key":"134_CR11","doi-asserted-by":"publisher","first-page":"69.","DOI":"10.1167\/iovs.66.4.69","volume":"66","author":"SK Ha","year":"2025","unstructured":"Ha SK, Ding X, Romano F, Overbey KM, Vingopoulos F, Garg I, et al. Structure-function associations between quantitative contrast sensitivity function and peripapillary optical coherence tomography angiography in diabetic retinopathy. Invest Ophthalmol Vis Sci. 2025;66:69. https:\/\/doi.org\/10.1167\/iovs.66.4.69.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"134_CR12","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/j.ajo.2015.01.022","volume":"159","author":"K Ohno-Matsui","year":"2015","unstructured":"Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, et al. International photographic classification and grading system for myopic maculopathy. Am J Ophthalmol. 2015;159:877\u201383.e7. https:\/\/doi.org\/10.1016\/j.ajo.2015.01.022.","journal-title":"Am J Ophthalmol"},{"key":"134_CR13","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.ajo.2018.05.022","volume":"192","author":"MS Sung","year":"2018","unstructured":"Sung MS, Heo H, Park SW. Microstructure of parapapillary atrophy is associated with parapapillary microvasculature in myopic eyes. Am J Ophthalmol. 2018;192:157\u201368. https:\/\/doi.org\/10.1016\/j.ajo.2018.05.022.","journal-title":"Am J Ophthalmol"},{"key":"134_CR14","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1016\/s0161-6420(00)00284-0","volume":"107","author":"DF Garway-Heath","year":"2000","unstructured":"Garway-Heath DF, Poinoosawmy D, Fitzke FW, Hitchings RA. Mapping the visual field to the optic disc in normal tension glaucoma eyes. Ophthalmology. 2000;107:1809\u201315. https:\/\/doi.org\/10.1016\/s0161-6420(00)00284-0.","journal-title":"Ophthalmology"},{"key":"134_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.941051","volume":"13","author":"J Ye","year":"2022","unstructured":"Ye J, Liu W, Hu X, Jiang H, Xu M, Jin H, et al. Elevated pulse pressure correlated with reduced retinal peripapillary capillary in thyroid-associated ophthalmology with visual field defect. Front Endocrinol. 2022;13:941051. https:\/\/doi.org\/10.3389\/fendo.2022.941051.","journal-title":"Front Endocrinol"},{"key":"134_CR16","doi-asserted-by":"publisher","first-page":"e013571.","DOI":"10.1136\/bmjopen-2016-013571","volume":"7","author":"J Mo","year":"2017","unstructured":"Mo J, Duan A, Chan S, Wang X, Wei W. Vascular flow density in pathological myopia: an optical coherence tomography angiography study. BMJ Open. 2017;7:e013571. https:\/\/doi.org\/10.1136\/bmjopen-2016-013571.","journal-title":"BMJ Open"},{"key":"134_CR17","doi-asserted-by":"publisher","first-page":"274","DOI":"10.18240\/ijo.2018.02.16","volume":"11","author":"ELM Tai","year":"2018","unstructured":"Tai ELM, Ling JL, Gan EH, Adil H, Wan-Hazabbah WH. Comparison of peripapillary retinal nerve fiber layer thickness between myopia severity groups and controls. Int J Ophthalmol. 2018;11:274\u20138. https:\/\/doi.org\/10.18240\/ijo.2018.02.16.","journal-title":"Int J Ophthalmol"},{"key":"134_CR18","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.818530","volume":"16","author":"J Ye","year":"2022","unstructured":"Ye J, Lin J, Shen M, Chen W, Zhang R, Lu F, et al. Reduced radial peripapillary capillary in pathological myopia is correlated with visual acuity. Front Neurosci. 2022;16:818530. https:\/\/doi.org\/10.3389\/fnins.2022.818530.","journal-title":"Front Neurosci"},{"key":"134_CR19","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.ajo.2018.01.033","volume":"188","author":"MS Sung","year":"2018","unstructured":"Sung MS, Lee TH, Heo H, Park SW. Association between optic nerve head deformation and retinal microvasculature in high myopia. Am J Ophthalmol. 2018;188:81\u201390. https:\/\/doi.org\/10.1016\/j.ajo.2018.01.033.","journal-title":"Am J Ophthalmol"},{"key":"134_CR20","doi-asserted-by":"publisher","first-page":"e010791.","DOI":"10.1136\/bmjopen-2015-010791","volume":"6","author":"X Wang","year":"2016","unstructured":"Wang X, Kong X, Jiang C, Li M, Yu J, Sun X. Is the peripapillary retinal perfusion related to myopia in healthy eyes? A prospective comparative study. BMJ Open. 2016;6:e010791. https:\/\/doi.org\/10.1136\/bmjopen-2015-010791.","journal-title":"BMJ Open"},{"key":"134_CR21","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.ajo.2018.05.027","volume":"192","author":"HL Park","year":"2018","unstructured":"Park HL, Jeon SJ, Park CK. Features of the choroidal microvasculature in peripapillary atrophy are associated with visual field damage in myopic patients. Am J Ophthalmol. 2018;192:206\u201316. https:\/\/doi.org\/10.1016\/j.ajo.2018.05.027.","journal-title":"Am J Ophthalmol"},{"key":"134_CR22","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1097\/IAE.0000000000003333","volume":"42","author":"F Zheng","year":"2022","unstructured":"Zheng F, Chua J, Sim YC, Tan B, Yu M, Wong QY, et al. Macular sensitivity and capillary perfusion in highly myopic eyes with myopic macular degeneration. Retina. 2022;42:529\u201339. https:\/\/doi.org\/10.1097\/IAE.0000000000003333.","journal-title":"Retina"},{"key":"134_CR23","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1136\/bjophthalmol-2015-307942","volume":"100","author":"X Ding","year":"2016","unstructured":"Ding X, Chang RT, Guo X, Liu X, Johnson CA, Holden BA, et al. Visual field defect classification in the Zhongshan Ophthalmic Center-Brien Holden Vision Institute High Myopia Registry Study. Br J Ophthalmol. 2016;100:1697\u2013702. https:\/\/doi.org\/10.1136\/bjophthalmol-2015-307942.","journal-title":"Br J Ophthalmol"},{"key":"134_CR24","first-page":"66","volume":"25","author":"DC Broadway","year":"2012","unstructured":"Broadway DC. Visual field testing for glaucoma\u2014a practical guide. Community Eye Health. 2012;25:66\u201370.","journal-title":"Community Eye Health"},{"key":"134_CR25","doi-asserted-by":"publisher","first-page":"5713","DOI":"10.1167\/iovs.17-22865","volume":"58","author":"G Triolo","year":"2017","unstructured":"Triolo G, Rabiolo A, Shemonski ND, Fard A, Di Matteo F, Sacconi R, et al. Optical coherence tomography angiography macular and peripapillary vessel perfusion density in healthy subjects, glaucoma suspects, and glaucoma patients. Invest Ophthalmol Vis Sci. 2017;58:5713\u201322. https:\/\/doi.org\/10.1167\/iovs.17-22865.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"134_CR26","doi-asserted-by":"publisher","first-page":"4146","DOI":"10.4103\/ijo.IJO_1456_22","volume":"70","author":"A Dutta","year":"2022","unstructured":"Dutta A, Thulasidas M, Sasidharan A, Pradeep B, Rajesh Prabu V. Comparison of peripapillary capillary plexus using optical coherence tomography angiography and retinal nerve fibre layer analysis using spectral domain optical coherence tomography in glaucoma patients, glaucoma suspects, and healthy subjects. Indian J Ophthalmol. 2022;70:4146\u201351. https:\/\/doi.org\/10.4103\/ijo.IJO_1456_22.","journal-title":"Indian J Ophthalmol"},{"key":"134_CR27","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/j.ajo.2012.03.028","volume":"154","author":"HY Park","year":"2012","unstructured":"Park HY, Jung KI, Na KS, Park SH, Park CK. Visual field characteristics in normal-tension glaucoma patients with autonomic dysfunction and abnormal peripheral microcirculation. Am J Ophthalmol. 2012;154:466\u201375.e1. https:\/\/doi.org\/10.1016\/j.ajo.2012.03.028.","journal-title":"Am J Ophthalmol"},{"key":"134_CR28","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1097\/IAE.0000000000001464","volume":"37","author":"JB Jonas","year":"2017","unstructured":"Jonas JB, Ohno-Matsui K, Jiang WJ, Panda-Jonas S. Bruch membrane and the mechanism of myopization: a new theory. Retina. 2017;37:1428\u201340. https:\/\/doi.org\/10.1097\/IAE.0000000000001464.","journal-title":"Retina"},{"key":"134_CR29","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1016\/j.ophtha.2018.02.002","volume":"125","author":"KM Lee","year":"2018","unstructured":"Lee KM, Choung HK, Kim M, Oh S, Kim SH. Positional change of optic nerve head vasculature during axial elongation as evidence of lamina cribrosa shifting: Boramae Myopia Cohort Study Report 2. Ophthalmology. 2018;125:1224\u201333. https:\/\/doi.org\/10.1016\/j.ophtha.2018.02.002.","journal-title":"Ophthalmology"},{"key":"134_CR30","doi-asserted-by":"publisher","first-page":"45.","DOI":"10.1167\/iovs.61.4.45","volume":"61","author":"J Ye","year":"2020","unstructured":"Ye J, Wang M, Shen M, Huang S, Xue A, Lin J, et al. Deep retinal capillary plexus decreasing correlated with the outer retinal layer alteration and visual acuity impairment in pathological myopia. Invest Ophthalmol Vis Sci. 2020;61:45. https:\/\/doi.org\/10.1167\/iovs.61.4.45.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"134_CR31","doi-asserted-by":"publisher","first-page":"e0159911.","DOI":"10.1371\/journal.pone.0159911","volume":"11","author":"X Wang","year":"2016","unstructured":"Wang X, Zheng Y, Kong X, Zhu L, Sun X. The characteristics of peripapillary retinal perfusion by optical coherence tomography angiography in tessellated fundus eyes. PLoS ONE. 2016;11:e0159911. https:\/\/doi.org\/10.1371\/journal.pone.0159911.","journal-title":"PLoS ONE"},{"key":"134_CR32","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1016\/j.ophtha.2017.12.005","volume":"125","author":"Y Fang","year":"2018","unstructured":"Fang Y, Yokoi T, Nagaoka N, Shinohara K, Onishi Y, Ishida T, et al. Progression of myopic maculopathy during 18-year follow-up. Ophthalmology. 2018;125:863\u201377. https:\/\/doi.org\/10.1016\/j.ophtha.2017.12.005.","journal-title":"Ophthalmology"}],"container-title":["Ophthalmic and Physiological Optics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s44402-026-00134-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s44402-026-00134-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s44402-026-00134-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T09:51:43Z","timestamp":1788515503000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s44402-026-00134-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,11]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["134"],"URL":"https:\/\/doi.org\/10.1007\/s44402-026-00134-z","relation":{},"ISSN":["0275-5408","1475-1313"],"issn-type":[{"value":"0275-5408","type":"print"},{"value":"1475-1313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,11]]},"assertion":[{"value":"12 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 June 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing Interests","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"The current study was approved by the Ethics Committee of the Eye Hospital of Wenzhou Medical University, China, in accordance with the tenets of the Declaration of Helsinki. The reference number was 2021-014-K-11.","order":2,"name":"Ethics","label":"ETHICAL APPROVAL","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"Patients signed informed consent regarding publishing their data and photographs.","order":4,"name":"Ethics","label":"Consent to Publish","group":{"name":"EthicsHeading","label":"Ethics"}}]}}