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[\n                      \n                      ], the PDMH study protocol was approved by the Durham VAMC Institutional Review Board (IRB) and subsequently approved by local review boards of each participating site. Each enrolled study participant was asked to separately consent to baseline data collection and to repository data collection. Written informed consent specifically requested permission to (1) use blood samples for DNA\/RNA analyses, protein characterization, neurosteroid, and other small molecule analyses; (2) retrieve health care information from VA electronic medical records; (3) contact a friend or family member in the event that he\/she could not be reached for future studies or for emergencies; and (4) add blood, questionnaire data, neuroimaging, contact information (for him\/herself and friend\/family member), and\/or medical record information to a repository for future analyses or follow\u2010up studies. Participants were provided the opportunity to consent or decline consent\/access for each of these items separately.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable as data for this study were combined across participants.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"183"}}