{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T11:29:06Z","timestamp":1761391746759,"version":"3.40.3"},"publisher-location":"Cham","reference-count":97,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783030230807"},{"type":"electronic","value":"9783030230814"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/10_2018_66","type":"book-chapter","created":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T10:22:00Z","timestamp":1525861320000},"page":"1-29","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ionic Liquids in Bioseparation Processes"],"prefix":"10.1007","author":[{"given":"Diana C. V.","family":"Belchior","sequence":"first","affiliation":[]},{"given":"Iola F.","family":"Duarte","sequence":"additional","affiliation":[]},{"given":"Mara G.","family":"Freire","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2018,5,10]]},"reference":[{"key":"66_CR1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.seppur.2008.01.028","volume":"65","author":"M Mart\u00ednez-Arag\u00f3n","year":"2009","unstructured":"Mart\u00ednez-Arag\u00f3n M, Burghoff S, Goetheer ELV, de Haan AB (2009) Guidelines for solvent selection for carrier mediated extraction of proteins. Sep Purif Technol 65:65\u201372. https:\/\/doi.org\/10.1016\/j.seppur.2008.01.028","journal-title":"Sep Purif Technol"},{"key":"66_CR2","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.fluid.2005.12.011","volume":"241","author":"T Ahamed","year":"2006","unstructured":"Ahamed T, Ottens M, Nfor BK et al (2006) A generalized approach to thermodynamic properties of biomolecules for use in bioseparation process design. Fluid Phase Equilib 241:268\u2013282. https:\/\/doi.org\/10.1016\/j.fluid.2005.12.011","journal-title":"Fluid Phase Equilib"},{"key":"66_CR3","doi-asserted-by":"publisher","first-page":"B1","DOI":"10.1016\/0923-0467(94)87012-8","volume":"55","author":"CM Bhawsar","year":"1994","unstructured":"Bhawsar CM, Pandit B, Sawant B, Joshi B (1994) Enzyme mass transfer coefficient in a sieve plate extraction column. Chem Eng J 55:B1\u2013B17. https:\/\/doi.org\/10.1016\/0923-0467(94)87012-8","journal-title":"Chem Eng J"},{"key":"66_CR4","doi-asserted-by":"publisher","first-page":"6984","DOI":"10.1021\/acs.chemrev.6b00550","volume":"117","author":"SPM Ventura","year":"2017","unstructured":"Ventura SPM, Silva FA, Quental MV et al (2017) Ionic-liquid-mediated extraction and separation processes for bioactive compounds: past, present, and future trends. Chem Rev 117:6984\u20137052. https:\/\/doi.org\/10.1021\/acs.chemrev.6b00550","journal-title":"Chem Rev"},{"key":"66_CR5","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1039\/B006677J","volume":"37","author":"NV Plechkova","year":"2008","unstructured":"Plechkova NV, Seddon KR (2008) Applications of ionic liquids in the chemical industry. Chem Soc Rev 37:123\u2013150. https:\/\/doi.org\/10.1039\/B006677J","journal-title":"Chem Soc Rev"},{"key":"66_CR6","volume-title":"Partition of cell particles and macromolecules: separation and purification of biomolecules, cell organelles, membranes, and cells in aqueous polymer two-phase systems and their use in biochemical analysis and biotechnology","author":"P Albertsson","year":"1986","unstructured":"Albertsson P (1986) Partition of cell particles and macromolecules: separation and purification of biomolecules, cell organelles, membranes, and cells in aqueous polymer two-phase systems and their use in biochemical analysis and biotechnology.3rd edn. Wiley, Chichester","edition":"3"},{"key":"66_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12575-016-0048-8","volume":"18","author":"M Iqbal","year":"2016","unstructured":"Iqbal M, Tao Y, Xie S et al (2016) Aqueous two-phase system (ATPS): an overview and advances in its applications. Biol Proced Online 18:1\u201318. https:\/\/doi.org\/10.1186\/s12575-016-0048-8","journal-title":"Biol Proced Online"},{"key":"66_CR8","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1080\/15422119.2014.983128","volume":"45","author":"AL Grilo","year":"2014","unstructured":"Grilo AL, Aires-Barros MR, Azevedo AM (2014) Partitioning in aqueous two-phase systems: fundamentals, applications and trends. Sep Purif Rev 45:68\u201380. https:\/\/doi.org\/10.1080\/15422119.2014.983128","journal-title":"Sep Purif Rev"},{"key":"66_CR9","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1002\/(SICI)1097-4660(199911)74:11<1110::AID-JCTB149>3.0.CO;2-B","volume":"74","author":"AM Azevedo","year":"1999","unstructured":"Azevedo AM, Fonseca LP, Prazeres DMF (1999) Stability and stabilisation of penicillin acylase. J Chem Technol Biotechnol 74:1110\u20131116. https:\/\/doi.org\/10.1002\/(SICI)1097-4660(199911)74:11<1110::AID-JCTB149>3.0.CO;2-B","journal-title":"J Chem Technol Biotechnol"},{"key":"66_CR10","doi-asserted-by":"publisher","first-page":"19580","DOI":"10.1039\/c3cp53701c","volume":"15","author":"JFB Pereira","year":"2013","unstructured":"Pereira JFB, Rebelo LPN, Rogers RD et al (2013) Combining ionic liquids and polyethylene glycols to boost the hydrophobic-hydrophilic range of aqueous biphasic systems. Phys Chem Chem Phys 15:19580\u201319583. https:\/\/doi.org\/10.1039\/c3cp53701c","journal-title":"Phys Chem Chem Phys"},{"key":"66_CR11","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1021\/bm034069l","volume":"4","author":"J Li","year":"2003","unstructured":"Li J, Kao WJ (2003) Synthesis of polyethylene glycol (PEG) derivatives and PEGylated - peptide biopolymer conjugates. Biomacromolecules 4:1055\u20131067. https:\/\/doi.org\/10.1021\/bm034069l","journal-title":"Biomacromolecules"},{"key":"66_CR12","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.chroma.2007.03.067","volume":"1162","author":"PAJ Rosa","year":"2007","unstructured":"Rosa PAJ, Azevedo AM, Ferreira IF et al (2007) Affinity partitioning of human antibodies in aqueous two-phase systems. J Chromatogr A 1162:103\u2013113. https:\/\/doi.org\/10.1016\/j.chroma.2007.03.067","journal-title":"J Chromatogr A"},{"key":"66_CR13","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1039\/c003578e","volume":"12","author":"JFB Pereira","year":"2010","unstructured":"Pereira JFB, Lima \u00c1S, Freire MG, Coutinho JAP (2010) Ionic liquids as adjuvants for the tailored extraction of biomolecules in aqueous biphasic systems. Green Chem 12:1661. https:\/\/doi.org\/10.1039\/c003578e","journal-title":"Green Chem"},{"key":"66_CR14","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.chroma.2014.02.069","volume":"1339","author":"VL Dhadge","year":"2014","unstructured":"Dhadge VL, Rosa SASL, Azevedo AM et al (2014) Magnetic aqueous two-phase fishing: a hybrid process technology for antibody purification. J Chromatogr A 1339:59\u201364. https:\/\/doi.org\/10.1016\/j.chroma.2014.02.069","journal-title":"J Chromatogr A"},{"key":"66_CR15","doi-asserted-by":"publisher","first-page":"6632","DOI":"10.1021\/ja0351802","volume":"125","author":"KE Gutowski","year":"2003","unstructured":"Gutowski KE, Broker GA, Willauer HD et al (2003) Controlling the aqueous miscibility of ionic liquids: aqueous biphasic systems of water-miscible ionic liquids and water-structuring salts for recycle, metathesis, and separations. J Am Chem Soc 125:6632\u20136633. https:\/\/doi.org\/10.1021\/ja0351802","journal-title":"J Am Chem Soc"},{"key":"66_CR16","doi-asserted-by":"publisher","first-page":"4966","DOI":"10.1039\/c2cs35151j","volume":"41","author":"MG Freire","year":"2012","unstructured":"Freire MG, Cl\u00e1udio AFM, Ara\u00fajo JMM et al (2012) Aqueous biphasic systems: a boost brought about by using ionic liquids. Chem Soc Rev 41:4966\u20134995. https:\/\/doi.org\/10.1039\/c2cs35151j","journal-title":"Chem Soc Rev"},{"key":"66_CR17","doi-asserted-by":"publisher","first-page":"162","DOI":"10.11648\/j.css.20170204.15","volume":"2","author":"A Abd","year":"2017","unstructured":"Abd A, Ahmed A, Xiashi Z (2017) Developments\/application of ionic liquids\/poly ionic liquids in magnetic solid-phase extraction and solid phase microextraction. Colloid Surf Sci 2:162\u2013170. https:\/\/doi.org\/10.11648\/j.css.20170204.15","journal-title":"Colloid Surf Sci"},{"key":"66_CR18","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s00216-002-1684-1","volume":"375","author":"S Carda-Broch","year":"2003","unstructured":"Carda-Broch S, Berthod A, Armstrong DW (2003) Solvent properties of the 1-butyl-3-methylimidazolium hexafluorophosphate ionic liquid. Anal Bioanal Chem 375:191\u2013199. https:\/\/doi.org\/10.1007\/s00216-002-1684-1","journal-title":"Anal Bioanal Chem"},{"key":"66_CR19","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1007\/s00216-003-2398-8","volume":"378","author":"SV Smirnova","year":"2004","unstructured":"Smirnova SV, Torocheshnikova II, Formanovsky AA, Pletnev IV (2004) Solvent extraction of amino acids into a room temperature ionic liquid with dicyclohexano-18-crown-6. Anal Bioanal Chem 378:1369\u20131375. https:\/\/doi.org\/10.1007\/s00216-003-2398-8","journal-title":"Anal Bioanal Chem"},{"key":"66_CR20","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1039\/b415842c","volume":"7","author":"J Wang","year":"2005","unstructured":"Wang J, Pei Y, Zhao Y, Hu Z (2005) Recovery of amino acids by imidazolium based ionic liquids from aqueous media. Green Chem 7:196\u2013202. https:\/\/doi.org\/10.1039\/b415842c","journal-title":"Green Chem"},{"key":"66_CR21","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/s00726-009-0391-z","volume":"39","author":"G Absalan","year":"2010","unstructured":"Absalan G, Akhond M, Sheikhian L (2010) Partitioning of acidic, basic and neutral amino acids into imidazolium-based ionic liquids. Amino Acids 39:167\u2013174. https:\/\/doi.org\/10.1007\/s00726-009-0391-z","journal-title":"Amino Acids"},{"key":"66_CR22","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.seppur.2010.02.002","volume":"72","author":"LIN Tom\u00e9","year":"2010","unstructured":"Tom\u00e9 LIN, Catambas VR, Teles ARR et al (2010) Tryptophan extraction using hydrophobic ionic liquids. Sep Purif Technol 72:167\u2013173. https:\/\/doi.org\/10.1016\/j.seppur.2010.02.002","journal-title":"Sep Purif Technol"},{"key":"66_CR23","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1039\/c2gc16560k","volume":"14","author":"L Huaxi","year":"2012","unstructured":"Huaxi L, Zhuo L, Jingmei Y et al (2012) Liquid\u2013liquid extraction process of amino acids by a new amide-based functionalized ionic liquid. Green Chem 14:172\u20131727. https:\/\/doi.org\/10.1039\/c2gc16560k","journal-title":"Green Chem"},{"key":"66_CR24","doi-asserted-by":"publisher","first-page":"4669","DOI":"10.1016\/j.chroma.2010.05.013","volume":"1217","author":"F Tang","year":"2010","unstructured":"Tang F, Zhang Q, Ren D et al (2010) Functional amino acid ionic liquids as solvent and selector in chiral extraction. J Chromatogr A 1217:4669\u20134674. https:\/\/doi.org\/10.1016\/j.chroma.2010.05.013","journal-title":"J Chromatogr A"},{"key":"66_CR25","doi-asserted-by":"publisher","first-page":"7735","DOI":"10.1021\/ac0612877","volume":"78","author":"K Shimojo","year":"2006","unstructured":"Shimojo K, Kamiya N, Tani F et al (2006) Functional conversion of cytochrome c in ionic liquids via crown ether Complexation. Anal Chem 78:7735\u20137742. https:\/\/doi.org\/10.1021\/ac0612877","journal-title":"Anal Chem"},{"key":"66_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.chroma.2008.02.118","volume":"1193","author":"YP Tzeng","year":"2008","unstructured":"Tzeng YP, Shen CW, Yu T (2008) Liquid-liquid extraction of lysozyme using a dye-modified ionic liquid. J Chromatogr A 1193:1\u20136. https:\/\/doi.org\/10.1016\/j.chroma.2008.02.118","journal-title":"J Chromatogr A"},{"key":"66_CR27","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1039\/c0py00364f","volume":"2","author":"Y Kohno","year":"2011","unstructured":"Kohno Y, Saita S, Murata K et al (2011) Extraction of proteins with temperature sensitive and reversible phase change of ionic liquid\/water mixture. Polym Chem 2:862\u2013867. https:\/\/doi.org\/10.1039\/c0py00364f","journal-title":"Polym Chem"},{"key":"66_CR28","doi-asserted-by":"publisher","first-page":"18350","DOI":"10.3390\/ijms140918350","volume":"14","author":"Y Ito","year":"2013","unstructured":"Ito Y, Kohno Y, Nakamura N, Ohno H (2013) Design of phosphonium-type zwitterion as an additive to improve saturated water content of phase-separated ionic liquid from aqueous phase toward reversible extraction of proteins. Int J Mol Sci 14:18350\u201318361. https:\/\/doi.org\/10.3390\/ijms140918350","journal-title":"Int J Mol Sci"},{"key":"66_CR29","doi-asserted-by":"publisher","first-page":"5665","DOI":"10.1007\/s00253-014-5737-0","volume":"98","author":"W Xu","year":"2014","unstructured":"Xu W, Cao H, Ren G et al (2014) An AIL\/IL-based liquid\/liquid extraction system for the purification of His-tagged proteins. Appl Microbiol Biotechnol 98:5665\u20135675. https:\/\/doi.org\/10.1007\/s00253-014-5737-0","journal-title":"Appl Microbiol Biotechnol"},{"key":"66_CR30","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.seppur.2015.03.025","volume":"146","author":"G Ren","year":"2015","unstructured":"Ren G, Gong X, Wang B et al (2015) Affinity ionic liquids for the rapid liquid-liquid extraction purification of hexahistidine tagged proteins. Sep Purif Technol 146:114\u2013120. https:\/\/doi.org\/10.1016\/j.seppur.2015.03.025","journal-title":"Sep Purif Technol"},{"key":"66_CR31","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1016\/j.talanta.2008.01.044","volume":"75","author":"DH Cheng","year":"2008","unstructured":"Cheng DH, Chen XW, Shu Y, Wang JH (2008) Selective extraction\/isolation of hemoglobin with ionic liquid 1-butyl-3-trimethylsilylimidazolium hexafluorophosphate (BtmsimPF6). Talanta 75:1270\u20131278. https:\/\/doi.org\/10.1016\/j.talanta.2008.01.044","journal-title":"Talanta"},{"key":"66_CR32","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/S1872-2040(08)60066-3","volume":"36","author":"D-H Cheng","year":"2008","unstructured":"Cheng D-H, Chen X-W, Shu Y, Wang J-H (2008) Extraction of cytochrome C by ionic liquid 1-butyl-3-trimethylsilylimidazolium hexafluorophosphate. Chinese J Anal Chem 36:1187\u20131190. https:\/\/doi.org\/10.1016\/S1872-2040(08)60066-3","journal-title":"Chinese J Anal Chem"},{"key":"66_CR33","doi-asserted-by":"publisher","first-page":"14103(10)","DOI":"10.1063\/1.3298608","volume":"4","author":"YS Huh","year":"2010","unstructured":"Huh YS, Jeong CM, Chang HN et al (2010) Rapid separation of bacteriorhodopsin using a laminar-flow extraction system in a microfluidic device. Biomicrofluidics 4:14103(10)\u201314103(1). https:\/\/doi.org\/10.1063\/1.3298608","journal-title":"Biomicrofluidics"},{"key":"66_CR34","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.seppur.2012.08.010","volume":"98","author":"E Alvarez-Guerra","year":"2012","unstructured":"Alvarez-Guerra E, Irabien A (2012) Extraction of lactoferrin with hydrophobic ionic liquids. Sep Purif Technol 98:432\u2013440. https:\/\/doi.org\/10.1016\/j.seppur.2012.08.010","journal-title":"Sep Purif Technol"},{"key":"66_CR35","doi-asserted-by":"publisher","first-page":"9304","DOI":"10.1021\/jp900293v","volume":"113","author":"PM Ventura","year":"2009","unstructured":"Ventura PM, Neves CMSS, Freire MG et al (2009) Evaluation of anion influence on the formation and extraction capability of ionic-liquid-based aqueous biphasic systems. J Phys Chem B 113:9304\u20139310. https:\/\/doi.org\/10.1021\/jp900293v","journal-title":"J Phys Chem B"},{"key":"66_CR36","doi-asserted-by":"publisher","first-page":"5194","DOI":"10.1021\/jp900293v","volume":"113","author":"CMSS Neves","year":"2009","unstructured":"Neves CMSS, Ventura SPM, Freire MG et al (2009) Evaluation of cation influence on the formation and extraction capability of ionic-liquid-based aqueous biphasic systems. J Phys Chem B 113:5194\u20135199. https:\/\/doi.org\/10.1021\/jp900293v","journal-title":"J Phys Chem B"},{"key":"66_CR37","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1016\/j.jct.2010.03.010","volume":"42","author":"Z Li","year":"2010","unstructured":"Li Z, Pei Y, Liu L, Wang J (2010) (Liquid+liquid) equilibria for (acetate-based ionic liquids + inorganic salts) aqueous two-phase systems. J Chem Thermodyn 42:932\u2013937. https:\/\/doi.org\/10.1016\/j.jct.2010.03.010","journal-title":"J Chem Thermodyn"},{"key":"66_CR38","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.chroma.2012.01.087","volume":"1231","author":"Y Pei","year":"2012","unstructured":"Pei Y, Li Z, Liu L, Wang J (2012) Partitioning behavior of amino acids in aqueous two-phase systems formed by imidazolium ionic liquid and dipotassium hydrogen phosphate. J Chromatogr A 1231:2\u20137. https:\/\/doi.org\/10.1016\/j.chroma.2012.01.087","journal-title":"J Chromatogr A"},{"key":"66_CR39","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.3390\/ijms11041777","volume":"11","author":"CLS Louros","year":"2010","unstructured":"Louros CLS, Claudio AFM, Neves CMSS et al (2010) Extraction of biomolecules using phosphonium-based ionic liquids + K3PO4 aqueous biphasic systems. Int J Mol Sci 11:1777\u20131791. https:\/\/doi.org\/10.3390\/ijms11041777","journal-title":"Int J Mol Sci"},{"key":"66_CR40","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1002\/btpr.613","volume":"27","author":"MT Zafarani-Moattar","year":"2011","unstructured":"Zafarani-Moattar MT, Hamzehzadeh S (2011) Partitioning of amino acids in the aqueous biphasic system containing the water-miscible ionic liquid 1-butyl-3-methylimidazolium bromide and the water-structuring salt potassium citrate. Biotechnol Prog 27:986\u2013997. https:\/\/doi.org\/10.1002\/btpr.613","journal-title":"Biotechnol Prog"},{"key":"66_CR41","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.bej.2012.05.004","volume":"67","author":"H Passos","year":"2012","unstructured":"Passos H, Ferreira AR, Cl\u00e1udio AFM et al (2012) Characterization of aqueous biphasic systems composed of ionic liquids and a citrate-based biodegradable salt. Biochem Eng J 67:68\u201376. https:\/\/doi.org\/10.1016\/j.bej.2012.05.004","journal-title":"Biochem Eng J"},{"key":"66_CR42","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.chroma.2015.03.047","volume":"1395","author":"D Wu","year":"2015","unstructured":"Wu D, Zhou Y, Cai P et al (2015) Specific cooperative effect for the enantiomeric separation of amino acids using aqueous two-phase systems with task-specific ionic liquids. J Chromatogr A 1395:65\u201372. https:\/\/doi.org\/10.1016\/j.chroma.2015.03.047","journal-title":"J Chromatogr A"},{"key":"66_CR43","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1021\/je700727u","volume":"53","author":"A Salabat","year":"2008","unstructured":"Salabat A, Abnosi MH, Motahari A (2008) Investigation of amino acid partitioning in aqueous two-phase systems containing polyethylene glycol and inorganic salts. J Chem Eng Data 53:2018\u20132021. https:\/\/doi.org\/10.1021\/je700727u","journal-title":"J Chem Eng Data"},{"key":"66_CR44","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1002\/btpr.718","volume":"28","author":"MT Zafarani-Moattar","year":"2011","unstructured":"Zafarani-Moattar MT, Hamzehzadeh S, Nasiri S (2011) A new aqueous biphasic system containing polypropylene glycol and a water-miscible ionic liquid. Biotechnol Prog 28:146\u2013156. https:\/\/doi.org\/10.1002\/btpr.718","journal-title":"Biotechnol Prog"},{"key":"66_CR45","doi-asserted-by":"publisher","first-page":"3365","DOI":"10.1021\/acssuschemeng.5b01068","volume":"3","author":"Y Xie","year":"2015","unstructured":"Xie Y, Xing H, Yang Q et al (2015) Aqueous biphasic system containing long chain anion-functionalized ionic liquids for high-performance extraction. ACS Sustain Chem Eng 3:3365\u20133372. https:\/\/doi.org\/10.1021\/acssuschemeng.5b01068","journal-title":"ACS Sustain Chem Eng"},{"key":"66_CR46","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1039\/c1gc15110j","volume":"13","author":"MG Freire","year":"2011","unstructured":"Freire MG, Louros CLS, Rebelo LPN, Coutinho JAP (2011) Aqueous biphasic systems composed of a water-stable ionic liquid + carbohydrates and their applications. Green Chem 13:1536\u20131545. https:\/\/doi.org\/10.1039\/c1gc15110j","journal-title":"Green Chem"},{"key":"66_CR47","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.bej.2015.05.008","volume":"101","author":"A Luis","year":"2015","unstructured":"Luis A, Dinis TBV, Passos H et al (2015) Good\u2019s buffers as novel phase-forming components of ionic-liquid-based aqueous biphasic systems. Biochem Eng J 101:142\u2013149. https:\/\/doi.org\/10.1016\/j.bej.2015.05.008","journal-title":"Biochem Eng J"},{"key":"66_CR48","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1039\/C6GC03060B","volume":"19","author":"EV Capela","year":"2017","unstructured":"Capela EV, Quental MV, Domingues P et al (2017) Effective separation of aromatic and aliphatic amino acid mixtures using ionic-liquid-based aqueous biphasic systems. Green Chem 19:1850\u20131854. https:\/\/doi.org\/10.1039\/C6GC03060B","journal-title":"Green Chem"},{"key":"66_CR49","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.fluid.2014.08.029","volume":"382","author":"S Hamzehzadeh","year":"2014","unstructured":"Hamzehzadeh S, Vasiresh M (2014) Ionic liquid 1-butyl-3-methylimidazolium bromide as a promoter for the formation and extraction capability of poly(ethylene glycol)-potassium citrate aqueous biphasic system at T=298.15K. Fluid Phase Equilib 382:80\u201388. https:\/\/doi.org\/10.1016\/j.fluid.2014.08.029","journal-title":"Fluid Phase Equilib"},{"key":"66_CR50","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1016\/j.talanta.2011.06.058","volume":"85","author":"Y Lu","year":"2011","unstructured":"Lu Y, Lu W, Wang W et al (2011) Thermodynamic studies of partitioning behavior of cytochrome c in ionic liquid-based aqueous two-phase system. Talanta 85:1621\u20131626. https:\/\/doi.org\/10.1016\/j.talanta.2011.06.058","journal-title":"Talanta"},{"key":"66_CR51","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.bej.2009.05.005","volume":"46","author":"S Dreyer","year":"2009","unstructured":"Dreyer S, Salim P, Kragl U (2009) Driving forces of protein partitioning in an ionic liquid-based aqueous two-phase system. Biochem Eng J 46:176\u2013185. https:\/\/doi.org\/10.1016\/j.bej.2009.05.005","journal-title":"Biochem Eng J"},{"key":"66_CR52","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1080\/01496395.2011.609241","volume":"47","author":"Y Pei","year":"2012","unstructured":"Pei Y, Li L, Li Z et al (2012) Partitioning behavior of wastewater proteins in some ionic liquids-based aqueous two-phase systems. Sep Sci Technol 47:277\u2013283. https:\/\/doi.org\/10.1080\/01496395.2011.609241","journal-title":"Sep Sci Technol"},{"key":"66_CR53","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1016\/j.jlumin.2011.10.026","volume":"132","author":"H Yan","year":"2012","unstructured":"Yan H, Wu J, Dai G et al (2012) Interaction mechanisms of ionic liquids [Cnmim]Br (n = 4, 6, 8, 10) with bovine serum albumin. J Lumin 132:622\u2013628. https:\/\/doi.org\/10.1016\/j.jlumin.2011.10.026","journal-title":"J Lumin"},{"key":"66_CR54","doi-asserted-by":"publisher","first-page":"6445","DOI":"10.1039\/c3an01301d","volume":"138","author":"X Lin","year":"2013","unstructured":"Lin X, Wang Y, Zeng Q et al (2013) Extraction and separation of proteins by ionic liquid aqueous two-phase system. Analyst 138:6445\u20136453. https:\/\/doi.org\/10.1039\/c3an01301d","journal-title":"Analyst"},{"key":"66_CR55","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1007\/s11426-010-4025-9","volume":"53","author":"Y Pei","year":"2010","unstructured":"Pei Y, Li Z, Liu L et al (2010) Selective separation of protein and saccharides by ionic liquids aqueous two-phase systems. Sci China Chem 53:1554\u20131560. https:\/\/doi.org\/10.1007\/s11426-010-4025-9","journal-title":"Sci China Chem"},{"key":"66_CR56","doi-asserted-by":"publisher","first-page":"2372","DOI":"10.1080\/01496395.2013.804086","volume":"48","author":"L Sheikhian","year":"2013","unstructured":"Sheikhian L, Akhond M, Absalan G, Goltz DM (2013) Dye-affinity partitioning of acidic, basic, and neutral proteins in ionic liquid-based aqueous biphasic systems. Sep Sci Technol 48:2372\u20132380. https:\/\/doi.org\/10.1080\/01496395.2013.804086","journal-title":"Sep Sci Technol"},{"key":"66_CR57","doi-asserted-by":"publisher","first-page":"4067","DOI":"10.1039\/c4ay00233d","volume":"6","author":"J Chen","year":"2014","unstructured":"Chen J, Wang Y, Zeng Q et al (2014) Partition of proteins with extraction in aqueous two-phase system by hydroxyl ammonium-based ionic liquid. Anal Methods 6:4067\u20134076. https:\/\/doi.org\/10.1039\/c4ay00233d","journal-title":"Anal Methods"},{"key":"66_CR58","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1016\/j.ijbiomac.2015.09.036","volume":"81","author":"M Bisht","year":"2015","unstructured":"Bisht M, Kumar A, Venkatesu P (2015) Analysis of the driving force that rule the stability of lysozyme in alkylammonium-based ionic liquids. Int J Biol Macromol 81:1074\u20131081. https:\/\/doi.org\/10.1016\/j.ijbiomac.2015.09.036","journal-title":"Int J Biol Macromol"},{"key":"66_CR59","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.procbio.2015.02.001","volume":"50","author":"JHPM Santos","year":"2015","unstructured":"Santos JHPM, E Silva FA, Coutinho JAP et al (2015) Ionic liquids as a novel class of electrolytes in polymeric aqueous biphasic systems. Process Biochem 50:661\u2013668. https:\/\/doi.org\/10.1016\/j.procbio.2015.02.001","journal-title":"Process Biochem"},{"key":"66_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.chroma.2013.06.066","volume":"1305","author":"C Wu","year":"2013","unstructured":"Wu C, Wang J, Li Z et al (2013) Relative hydrophobicity between the phases and partition of cytochrome-c in glycine ionic liquids aqueous two-phase systems. J Chromatogr A 1305:1\u20136. https:\/\/doi.org\/10.1016\/j.chroma.2013.06.066","journal-title":"J Chromatogr A"},{"key":"66_CR61","doi-asserted-by":"publisher","first-page":"3395","DOI":"10.1016\/B978-1-895198-85-0.50012-1","volume":"5","author":"S Huang","year":"2013","unstructured":"Huang S, Wang Y, Zhou Y et al (2013) Choline-like ionic liquid-based aqueous two-phase extraction of selected proteins. Anal Methods 5:3395\u20133402. https:\/\/doi.org\/10.1016\/B978-1-895198-85-0.50012-1","journal-title":"Anal Methods"},{"key":"66_CR62","doi-asserted-by":"publisher","first-page":"2941","DOI":"10.1039\/c2gc35890e","volume":"14","author":"Z Li","year":"2012","unstructured":"Li Z, Liu X, Pei Y et al (2012) Design of environmentally friendly ionic liquid aqueous two-phase systems for the efficient and high activity extraction of proteins. Green Chem 14:2941. https:\/\/doi.org\/10.1039\/c2gc35890e","journal-title":"Green Chem"},{"key":"66_CR63","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1016\/j.procbio.2015.03.020","volume":"50","author":"M Taha","year":"2015","unstructured":"Taha M, Quental MV, Correia I et al (2015) Extraction and stability of bovine serum albumin (BSA) using cholinium-based Good\u2019s buffers ionic liquids. Process Biochem 50:1158\u20131166. https:\/\/doi.org\/10.1016\/j.procbio.2015.03.020","journal-title":"Process Biochem"},{"key":"66_CR64","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1002\/biot.201500003","volume":"10","author":"MV Quental","year":"2015","unstructured":"Quental MV, Caban M, Pereira MM et al (2015) Enhanced extraction of proteins using cholinium-based ionic liquids as phase-forming components of aqueous biphasic systems. Biotechnol J 10:1457\u20131466. https:\/\/doi.org\/10.1002\/biot.201500003","journal-title":"Biotechnol J"},{"key":"66_CR65","doi-asserted-by":"publisher","first-page":"3291","DOI":"10.1021\/acssuschemeng.5b00881","volume":"3","author":"CP Song","year":"2015","unstructured":"Song CP, Ramanan RN, Vijayaraghavan R et al (2015) Aqueous two-phase systems based on cholinium aminoate ionic liquids with tunable hydrophobicity and charge density. ACS Sustain Chem Eng 3:3291\u20133298. https:\/\/doi.org\/10.1021\/acssuschemeng.5b00881","journal-title":"ACS Sustain Chem Eng"},{"key":"66_CR66","doi-asserted-by":"publisher","first-page":"3149","DOI":"10.1039\/C4GC00328D","volume":"16","author":"M Taha","year":"2014","unstructured":"Taha M, e Silva FA, Quental MV et al (2014) Good\u2019s buffers as a basis for developing self-buffering and biocompatible ionic liquids for biological research. Green Chem 16:3149\u20133159. https:\/\/doi.org\/10.1039\/C4GC00328D","journal-title":"Green Chem"},{"key":"66_CR67","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/srep20276","volume":"6","author":"H Passos","year":"2016","unstructured":"Passos H, Lu\u00eds A, Coutinho JAP, Freire MG (2016) Thermoreversible (ionic-liquid- based) aqueous biphasic systems. Sci Rep 6:1\u20137. https:\/\/doi.org\/10.1038\/srep20276","journal-title":"Sci Rep"},{"key":"66_CR68","doi-asserted-by":"publisher","first-page":"4781","DOI":"10.1002\/chem.201405693","volume":"21","author":"M Taha","year":"2015","unstructured":"Taha M, Almeida MR, Francisca A, Domingues P (2015) Novel biocompatible and self-buffering ionic liquids for biopharmaceutical applications. Chem Eur J 21:4781\u20134788. https:\/\/doi.org\/10.1002\/chem.201405693","journal-title":"Chem Eur J"},{"key":"66_CR69","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jbiotec.2016.08.015","volume":"236","author":"AM Ferreira","year":"2016","unstructured":"Ferreira AM, Faustino VFM, Mondal D et al (2016) Improving the extraction and purification of immunoglobulin G by the use of ionic liquids as adjuvants in aqueous biphasic systems. J Biotechnol 236:166\u2013175. https:\/\/doi.org\/10.1016\/j.jbiotec.2016.08.015","journal-title":"J Biotechnol"},{"issue":"7","key":"66_CR70","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1002\/jctb.5594","volume":"93","author":"Catarina C Ramalho","year":"2018","unstructured":"Ramalho CC, Neves CMSS, Quental MV et al (2018) Separation of immunoglobulin G using aqueous biphasic systems composed of cholinium-based ionic liquids and poly(propylene glycol). J Chem Technol Biotechnol. https:\/\/doi.org\/10.1002\/jctb.5594","journal-title":"Journal of Chemical Technology & Biotechnology"},{"key":"66_CR71","doi-asserted-by":"publisher","first-page":"6071","DOI":"10.1039\/C6GC01482H","volume":"18","author":"D Mondal","year":"2016","unstructured":"Mondal D, Sharma M, Quental MV et al (2016) Suitability of bio-based ionic liquids for the extraction and purification of IgG antibodies. Green Chem 18:6071\u20136081. https:\/\/doi.org\/10.1039\/C6GC01482H","journal-title":"Green Chem"},{"key":"66_CR72","doi-asserted-by":"publisher","first-page":"2670","DOI":"10.1039\/C3GC42631A","volume":"16","author":"RK Desai","year":"2014","unstructured":"Desai RK, Streefland M, Wijffels RH, Eppink MHM (2014) Extraction and stability of selected proteins in ionic liquid based aqueous two-phase systems. Green Chem 16:2670\u20132679. https:\/\/doi.org\/10.1039\/C3GC42631A","journal-title":"Green Chem"},{"key":"66_CR73","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.desal.2011.11.053","volume":"286","author":"ZJ Tan","year":"2012","unstructured":"Tan ZJ, Li FF, Xu XL, Xing JM (2012) Simultaneous extraction and purification of aloe poly saccharides and proteins using ionic liquid based aqueous two-phase system coupled with dialysis membrane. Desalination 286:389\u2013393. https:\/\/doi.org\/10.1016\/j.desal.2011.11.053","journal-title":"Desalination"},{"key":"66_CR74","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.seppur.2014.03.020","volume":"135","author":"JK Yan","year":"2014","unstructured":"Yan JK, Ma HL, Pei JJ et al (2014) Facile and effective separation of polysaccharides and proteins from Cordyceps sinensis mycelia by ionic liquid aqueous two-phase system. Sep Purif Technol 135:278\u2013284. https:\/\/doi.org\/10.1016\/j.seppur.2014.03.020","journal-title":"Sep Purif Technol"},{"key":"66_CR75","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jbiotec.2015.03.028","volume":"206","author":"MM Pereira","year":"2015","unstructured":"Pereira MM, Pedro SN, Quental MV et al (2015) Enhanced extraction of bovine serum albumin with aqueous biphasic systems of phosphonium- and ammonium-based ionic liquids. J Biotechnol 206:17\u201325. https:\/\/doi.org\/10.1016\/j.jbiotec.2015.03.028","journal-title":"J Biotechnol"},{"key":"66_CR76","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1039\/C0GC00075B","volume":"13","author":"FJ Deive","year":"2011","unstructured":"Deive FJ, Rodr\u00edguez A, Pereiro AB et al (2011) Ionic liquid-based aqueous biphasic system for lipase extraction. Green Chem 13:390\u2013396. https:\/\/doi.org\/10.1039\/C0GC00075B","journal-title":"Green Chem"},{"key":"66_CR77","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.seppur.2011.12.013","volume":"97","author":"FJ Deive","year":"2012","unstructured":"Deive FJ, Rodr\u00edguez A, Rebelo LPN, Marrucho IM (2012) Extraction of Candida antarctica lipase A from aqueous solutions using imidazolium-based ionic liquids. Sep Purif Technol 97:205\u2013210. https:\/\/doi.org\/10.1016\/j.seppur.2011.12.013","journal-title":"Sep Purif Technol"},{"key":"66_CR78","doi-asserted-by":"publisher","first-page":"2679","DOI":"10.1016\/j.jchromb.2011.07.022","volume":"879","author":"SPM Ventura","year":"2011","unstructured":"Ventura SPM, Sousa SG, Freire MG et al (2011) Design of ionic liquids for lipase purification. J Chromatogr B Anal Technol Biomed Life Sci 879:2679\u20132687. https:\/\/doi.org\/10.1016\/j.jchromb.2011.07.022","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"66_CR79","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1039\/c2gc16428k","volume":"14","author":"SPM Ventura","year":"2012","unstructured":"Ventura SPM, de Barros RLF, de Pinho Barbosa JM et al (2012) Production and purification of an extracellular lipolytic enzyme using ionic liquid-based aqueous two-phase systems. Green Chem 14:734\u2013740. https:\/\/doi.org\/10.1039\/c2gc16428k","journal-title":"Green Chem"},{"key":"66_CR80","doi-asserted-by":"publisher","first-page":"3026","DOI":"10.1039\/C5GC00262A","volume":"17","author":"RL Souza","year":"2015","unstructured":"Souza RL, Ventura SPM, Soares CMF et al (2015) Lipase purification using ionic liquids as adjuvants in aqueous two-phase systems. Green Chem 17:3026\u20133034. https:\/\/doi.org\/10.1039\/C5GC00262A","journal-title":"Green Chem"},{"key":"66_CR81","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.seppur.2015.05.021","volume":"155","author":"RL Souza","year":"2015","unstructured":"Souza RL, Lima RA, Coutinho JAP et al (2015) Aqueous two-phase systems based on cholinium salts and tetrahydrofuran and their use for lipase purification. Sep Purif Technol 155:118\u2013126. https:\/\/doi.org\/10.1016\/j.seppur.2015.05.021","journal-title":"Sep Purif Technol"},{"key":"66_CR82","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.procbio.2017.08.020","volume":"63","author":"SY Lee","year":"2017","unstructured":"Lee SY, Khoiroh I, Coutinho JAP et al (2017) Lipase production and purification by self-buffering ionic liquid-based aqueous biphasic systems. Process Biochem 63:221\u2013228. https:\/\/doi.org\/10.1016\/j.procbio.2017.08.020","journal-title":"Process Biochem"},{"key":"66_CR83","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2013\/938154","volume":"2013","author":"Z Bai","year":"2013","unstructured":"Bai Z, Chao Y, Zhang M et al (2013) Partitioning behavior of papain in ionic liquids-based aqueous two-phase systems. J Chem 2013:1\u20136. https:\/\/doi.org\/10.1155\/2013\/938154","journal-title":"J Chem"},{"key":"66_CR84","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.talanta.2008.05.055","volume":"77","author":"Q Cao","year":"2008","unstructured":"Cao Q, Quan L, He C et al (2008) Talanta partition of horseradish peroxidase with maintained activity in aqueous biphasic system based on ionic liquid. Talanta 77:160\u2013165. https:\/\/doi.org\/10.1016\/j.talanta.2008.05.055","journal-title":"Talanta"},{"key":"66_CR85","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1002\/btpr.1979","volume":"30","author":"J Simental-Mart\u00ednez","year":"2014","unstructured":"Simental-Mart\u00ednez J, Rito-Palomares M, Benavides J (2014) Potential application of aqueous two-phase systems and three-phase partitioning for the recovery of superoxide dismutase from a clarified homogenate of Kluyveromyces marxianus. Biotechnol Prog 30:1326\u20131334. https:\/\/doi.org\/10.1002\/btpr.1979","journal-title":"Biotechnol Prog"},{"issue":"7","key":"66_CR86","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.1002\/jctb.5455","volume":"93","author":"Jo\u00e3o HPM Santos","year":"2017","unstructured":"Santos JHPM, Santos JC et al (2018) In situ purification of periplasmatic L-asparaginase by aqueous two phase systems with ionic liquids (ILs) as adjuvants. J Chem Technol Biotechnol. https:\/\/doi.org\/10.1002\/jctb.5455","journal-title":"Journal of Chemical Technology & Biotechnology"},{"key":"66_CR87","doi-asserted-by":"publisher","first-page":"2878","DOI":"10.1007\/s13197-014-1319-5","volume":"52","author":"B Jiang","year":"2015","unstructured":"Jiang B, Feng Z, Liu C et al (2015) Extraction and purification of wheat-esterase using aqueous two-phase systems of ionic liquid and salt. J Food Sci Technol 52:2878\u20132885. https:\/\/doi.org\/10.1007\/s13197-014-1319-5","journal-title":"J Food Sci Technol"},{"key":"66_CR88","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.seppur.2012.01.033","volume":"97","author":"U Novak","year":"2012","unstructured":"Novak U, Pohar A, Plazl I, \u017dnidar\u0161i\u010d-Plazl P (2012) Ionic liquid-based aqueous two-phase extraction within a microchannel system. Sep Purif Technol 97:172\u2013178. https:\/\/doi.org\/10.1016\/j.seppur.2012.01.033","journal-title":"Sep Purif Technol"},{"key":"66_CR89","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.aca.2011.11.050","volume":"715","author":"L Vidal","year":"2012","unstructured":"Vidal L, Riekkola ML, Canals A (2012) Ionic liquid-modified materials for solid-phase extraction and separation: a review. Anal Chim Acta 715:19\u201341. https:\/\/doi.org\/10.1016\/j.aca.2011.11.050","journal-title":"Anal Chim Acta"},{"key":"66_CR90","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.trac.2015.04.011","volume":"71","author":"BH Fumes","year":"2015","unstructured":"Fumes BH, Silva MR, Andrade FN et al (2015) Recent advances and future trends in new materials for sample preparation. TrAC Trends Anal Chem 71:9\u201325. https:\/\/doi.org\/10.1016\/j.trac.2015.04.011","journal-title":"TrAC Trends Anal Chem"},{"key":"66_CR91","doi-asserted-by":"crossref","first-page":"7948","DOI":"10.1016\/S1452-3981(23)11018-2","volume":"9","author":"HM Marwani","year":"2014","unstructured":"Marwani HM, Bakhsh EM, Al-Turaif HA et al (2014) Enantioselective separation and detection of D-phenylalanine based on newly developed chiral ionic liquid immobilized silica gel surface. Int J Electrochem Sci 9:7948\u20137964","journal-title":"Int J Electrochem Sci"},{"key":"66_CR92","doi-asserted-by":"publisher","first-page":"42485(1)","DOI":"10.1002\/app.42485","volume":"132","author":"L Yang","year":"2015","unstructured":"Yang L, Hu X, Guan P et al (2015) Molecularly imprinted polymers for the selective recognition of L-phenylalanine based on 1-buty-3-methylimidazolium ionic liquid. J Appl Polym Sci 132:42485(1)\u201342485(9). https:\/\/doi.org\/10.1002\/app.42485","journal-title":"J Appl Polym Sci"},{"key":"66_CR93","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.talanta.2009.12.059","volume":"81","author":"Y Shu","year":"2010","unstructured":"Shu Y, Chen XW, Wang JH (2010) Ionic liquid-polyvinyl chloride ionomer for highly selective isolation of basic proteins. Talanta 81:637\u2013642. https:\/\/doi.org\/10.1016\/j.talanta.2009.12.059","journal-title":"Talanta"},{"key":"66_CR94","doi-asserted-by":"publisher","first-page":"5353","DOI":"10.1007\/s00216-013-6889-y","volume":"405","author":"G Zhao","year":"2013","unstructured":"Zhao G, Chen S, Chen XW, He RH (2013) Selective isolation of hemoglobin by use of imidazolium-modified polystyrene as extractant. Anal Bioanal Chem 405:5353\u20135358. https:\/\/doi.org\/10.1007\/s00216-013-6889-y","journal-title":"Anal Bioanal Chem"},{"key":"66_CR95","doi-asserted-by":"publisher","first-page":"52147","DOI":"10.1039\/C4RA05713A","volume":"4","author":"Y Liu","year":"2014","unstructured":"Liu Y, Ma R, Deng Q et al (2014) Preparation of ionic liquid polymer materials and their recognition properties for proteins. RSC Adv 4:52147\u201352154. https:\/\/doi.org\/10.1039\/C4RA05713A","journal-title":"RSC Adv"},{"key":"66_CR96","doi-asserted-by":"publisher","first-page":"8358","DOI":"10.1039\/C4AY01786B","volume":"6","author":"J Chen","year":"2014","unstructured":"Chen J, Wang Y, Ding X et al (2014) Magnetic solid-phase extraction of proteins based on hydroxy functional ionic liquid-modified magnetic nanoparticles. Anal Methods 6:8358\u20138367. https:\/\/doi.org\/10.1039\/C4AY01786B","journal-title":"Anal Methods"},{"key":"66_CR97","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.talanta.2016.07.031","volume":"160","author":"Q Wen","year":"2016","unstructured":"Wen Q, Wang Y, Xu K et al (2016) Magnetic solid-phase extraction of protein by ionic liquid-coated Fe@graphene oxide. Talanta 160:481\u2013488. https:\/\/doi.org\/10.1016\/j.talanta.2016.07.031","journal-title":"Talanta"}],"container-title":["Advances in Biochemical Engineering\/Biotechnology","Application of Ionic Liquids in Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/10_2018_66","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T14:26:24Z","timestamp":1693664784000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/10_2018_66"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9783030230807","9783030230814"],"references-count":97,"URL":"https:\/\/doi.org\/10.1007\/10_2018_66","relation":{},"ISSN":["0724-6145","1616-8542"],"issn-type":[{"type":"print","value":"0724-6145"},{"type":"electronic","value":"1616-8542"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"10 May 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}