{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T08:41:22Z","timestamp":1761986482183,"version":"3.40.5"},"publisher-location":"New York, NY","reference-count":47,"publisher":"Springer New York","isbn-type":[{"type":"print","value":"9781493918713"},{"type":"electronic","value":"9781493918720"}],"license":[{"start":{"date-parts":[[2014,10,18]],"date-time":"2014-10-18T00:00:00Z","timestamp":1413590400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2014,10,18]],"date-time":"2014-10-18T00:00:00Z","timestamp":1413590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"DOI":"10.1007\/978-1-4939-1872-0_5","type":"book-chapter","created":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T11:51:37Z","timestamp":1415965897000},"page":"83-100","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Glycoprotein Enrichment Method Using a Selective Magnetic Nano-Probe Platform (MNP) Functionalized with Lectins"],"prefix":"10.1007","author":[{"given":"Marta","family":"Cova","sequence":"first","affiliation":[]},{"given":"Rui","family":"Oliveira-Silva","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9 Alexandre","family":"Ferreira","sequence":"additional","affiliation":[]},{"given":"Rita","family":"Ferreira","sequence":"additional","affiliation":[]},{"given":"Francisco","family":"Amado","sequence":"additional","affiliation":[]},{"given":"Ana Lu\u00edsa","family":"Daniel-da-Silva","sequence":"additional","affiliation":[]},{"given":"Rui","family":"Vitorino","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2014,10,18]]},"reference":[{"key":"5_CR1","doi-asserted-by":"publisher","first-page":"207691","DOI":"10.4061\/2011\/207691","volume":"2011","author":"TM Karve","year":"2011","unstructured":"Karve TM, Cheema AK (2011) Small changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and disease. J Amino Acids 2011:207691","journal-title":"J Amino Acids"},{"key":"5_CR2","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1038\/446993a","volume":"446","author":"G Grotenbreg","year":"2007","unstructured":"Grotenbreg G, Ploegh H (2007) Chemical biology: dressed-up proteins. Nature 446:993\u2013995","journal-title":"Nature"},{"key":"5_CR3","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/j.cell.2006.08.019","volume":"126","author":"K Ohtsubo","year":"2006","unstructured":"Ohtsubo K, Marth JD (2006) Glycosylation in cellular mechanisms of health and disease. Cell 126:855\u2013867","journal-title":"Cell"},{"key":"5_CR4","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1136\/jcp.2009.071035","volume":"63","author":"CA Reis","year":"2010","unstructured":"Reis CA, Osorio H, Silva L et al (2010) Alterations in glycosylation as biomarkers for cancer detection. J Clin Pathol 63:322\u2013329","journal-title":"J Clin Pathol"},{"key":"5_CR5","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1093\/glycob\/3.2.97","volume":"3","author":"A Varki","year":"1993","unstructured":"Varki A (1993) Biological roles of oligosaccharides: all of the theories are correct. Glycobiology 3:97\u2013130","journal-title":"Glycobiology"},{"key":"5_CR6","doi-asserted-by":"publisher","first-page":"2364","DOI":"10.1126\/science.291.5512.2364","volume":"291","author":"A Helenius","year":"2001","unstructured":"Helenius A, Aebi M (2001) Intracellular functions of N-linked glycans. Science 291:2364\u20132369","journal-title":"Science"},{"key":"5_CR7","volume-title":"Essentials of glycobiology, chapter 18","author":"GW Hart","year":"2009","unstructured":"Hart GW, Akimoto Y (2009) The O-GlcNAc modification. In: Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME (eds) Essentials of glycobiology, chapter 18, 2nd edn. Cold Spring Harbor Laboratory Press, New York","edition":"2"},{"key":"5_CR8","volume-title":"Essentials of glycobiology, chapter 9","author":"I Brockhausen","year":"2009","unstructured":"Brockhausen I, Schachter H, Stanley P (2009) O-GalNAc Glycans. In: Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME (eds) Essentials of glycobiology, chapter 9, 2nd edn. Cold Spring Harbor Laboratory Press, New York","edition":"2"},{"key":"5_CR9","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1146\/annurev.biochem.72.121801.161809","volume":"72","author":"JB Lowe","year":"2003","unstructured":"Lowe JB, Marth JD (2003) A genetic approach to mammalian glycan function. Annu Rev Biochem 72:643\u2013691","journal-title":"Annu Rev Biochem"},{"key":"5_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/640923","volume":"2012","author":"Z Roth","year":"2012","unstructured":"Roth Z, Yehezkel G, Khalaila I (2012) Identification and quantification of protein glycosylation. Int J Carbohydr Chem 2012:1\u201310","journal-title":"Int J Carbohydr Chem"},{"key":"5_CR11","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1093\/bfgp\/eln053","volume":"8","author":"X Wei","year":"2009","unstructured":"Wei X, Li L (2009) Comparative glycoproteomics: approaches and applications. Brief Funct Genomic Proteomic 8:104\u2013113","journal-title":"Brief Funct Genomic Proteomic"},{"key":"5_CR12","doi-asserted-by":"publisher","first-page":"7035","DOI":"10.1021\/ac200916j","volume":"83","author":"JA Ferreira","year":"2011","unstructured":"Ferreira JA, Daniel-da-Silva AL, Alves RM et al (2011) Synthesis and optimization of lectin functionalized nanoprobes for the selective recovery of glycoproteins from human body fluids. Anal Chem 83:7035\u20137043","journal-title":"Anal Chem"},{"key":"5_CR13","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1039\/c2mb25288k","volume":"9","author":"Y Zhang","year":"2013","unstructured":"Zhang Y, Wang H, Lu H (2013) Sequential selective enrichment of phosphopeptides and glycopeptides using amine-functionalized magnetic nanoparticles. Mol Biosyst 9:492\u2013500","journal-title":"Mol Biosyst"},{"key":"5_CR14","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1038\/nmeth.2153","volume":"9","author":"A Doerr","year":"2012","unstructured":"Doerr A (2012) Making PTMs a priority. Nat Methods 9:862\u2013863","journal-title":"Nat Methods"},{"key":"5_CR15","doi-asserted-by":"publisher","first-page":"R73","DOI":"10.1186\/gb-2006-7-8-r73","volume":"7","author":"H Zhang","year":"2006","unstructured":"Zhang H, Loriaux P, Eng J et al (2006) UniPep\u2014a database for human N-linked glycosites: a resource for biomarker discovery. Genome Biol 7:R73","journal-title":"Genome Biol"},{"key":"5_CR16","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1074\/mcp.M600176-MCP200","volume":"5","author":"RR Drake","year":"2006","unstructured":"Drake RR, Schwegler EE, Malik G et al (2006) Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers. Mol Cell Proteomics 5:1957\u20131967","journal-title":"Mol Cell Proteomics"},{"key":"5_CR17","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1002\/jssc.201200434","volume":"35","author":"S Ongay","year":"2012","unstructured":"Ongay S, Boichenko A, Govorukhina N et al (2012) Glycopeptide enrichment and separation for protein glycosylation analysis. J Sep Sci 35:2341\u20132372","journal-title":"J Sep Sci"},{"key":"5_CR18","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/978-1-62703-146-2_10","volume":"951","author":"PH Jensen","year":"2013","unstructured":"Jensen PH, Mysling S, Hojrup P et al (2013) Glycopeptide enrichment for MALDI-TOF mass spectrometry analysis by hydrophilic interaction liquid chromatography solid phase extraction (HILIC SPE). Methods Mol Biol 951:131\u2013144","journal-title":"Methods Mol Biol"},{"key":"5_CR19","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/0021-9673(95)00220-0","volume":"720","author":"T Endo","year":"1996","unstructured":"Endo T (1996) Fractionation of glycoprotein-derived oligosaccharides by affinity chromatography using immobilized lectin columns. J Chromatogr A 720:251\u2013261","journal-title":"J Chromatogr A"},{"key":"5_CR20","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1002\/prca.201100042","volume":"6","author":"QK Li","year":"2012","unstructured":"Li QK, Gabrielson E, Zhang H (2012) Application of glycoproteomics for the discovery of biomarkers in lung cancer. Proteomics Clin Appl 6:244\u2013256","journal-title":"Proteomics Clin Appl"},{"issue":"R110","key":"5_CR21","first-page":"003251","volume":"10","author":"S Pan","year":"2011","unstructured":"Pan S, Chen R, Aebersold R et al (2011) Mass spectrometry based glycoproteomics\u2014from a proteomics perspective. Mol Cell Proteomics 10(R110):003251","journal-title":"Mol Cell Proteomics"},{"key":"5_CR22","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/S0021-9258(19)41842-5","volume":"250","author":"JW Becker","year":"1975","unstructured":"Becker JW, Reeke GN Jr, Wang JL et al (1975) The covalent and three-dimensional structure of concanavalin A. III. Structure of the monomer and its interactions with metals and saccharides. J Biol Chem 250:1513\u20131524","journal-title":"J Biol Chem"},{"key":"5_CR23","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0022-3565(25)20272-5","volume":"258","author":"N Bakry","year":"1991","unstructured":"Bakry N, Kamata Y, Simpson LL (1991) Lectins from Triticum vulgaris and Limax flavus are universal antagonists of botulinum neurotoxin and tetanus toxin. J Pharmacol Exp Ther 258:830\u2013836","journal-title":"J Pharmacol Exp Ther"},{"key":"5_CR24","doi-asserted-by":"publisher","first-page":"20890","DOI":"10.3390\/ijms141020890","volume":"14","author":"X Wang","year":"2013","unstructured":"Wang X, Xia N, Liu L (2013) Boronic Acid-based approach for separation and immobilization of glycoproteins and its application in sensing. Int J Mol Sci 14:20890\u201320912","journal-title":"Int J Mol Sci"},{"key":"5_CR25","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/nbt827","volume":"21","author":"H Zhang","year":"2003","unstructured":"Zhang H, Li XJ, Martin DB et al (2003) Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. Nat Biotechnol 21:660\u2013666","journal-title":"Nat Biotechnol"},{"key":"5_CR26","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1021\/pr034112b","volume":"3","author":"P Hagglund","year":"2004","unstructured":"Hagglund P, Bunkenborg J, Elortza F et al (2004) A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation. J Proteome Res 3:556\u2013566","journal-title":"J Proteome Res"},{"key":"5_CR27","doi-asserted-by":"publisher","first-page":"R167","DOI":"10.1088\/0022-3727\/36\/13\/201","volume":"36","author":"QA Pankhurst","year":"2003","unstructured":"Pankhurst QA, Connolly J, Jones SK et al (2003) Applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys 36:R167\u2013R181","journal-title":"J Phys D Appl Phys"},{"key":"5_CR28","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1477-3155-2-3","volume":"2","author":"O Salata","year":"2004","unstructured":"Salata O (2004) Applications of nanoparticles in biology and medicine. J Nanobiotechnol 2:3","journal-title":"J Nanobiotechnol"},{"key":"5_CR29","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1002\/anie.200602866","volume":"46","author":"A-H Lu","year":"2007","unstructured":"Lu A-H, Salabas EL, Sch\u00fcth F (2007) Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew Chem Int Ed Engl 46:1222\u20131244","journal-title":"Angew Chem Int Ed Engl"},{"key":"5_CR30","doi-asserted-by":"publisher","first-page":"8204","DOI":"10.1021\/ja026501x","volume":"124","author":"S Sun","year":"2002","unstructured":"Sun S, Zeng H (2002) Size-controlled synthesis of magnetite nanoparticles. J Am Chem Soc 124:8204\u20138205","journal-title":"J Am Chem Soc"},{"key":"5_CR31","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.1126\/science.1057553","volume":"291","author":"VF Puntes","year":"2001","unstructured":"Puntes VF, Krishnan KM, Alivisatos AP (2001) Colloidal nanocrystal shape and size control: the case of cobalt. Science 291:2115\u20132117","journal-title":"Science"},{"key":"5_CR32","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1021\/cm403047v","volume":"26","author":"KO Abdulwahab","year":"2014","unstructured":"Abdulwahab KO, Malik MA, O\u2019Brien P et al (2014) A one-pot synthesis of monodispersed iron cobalt oxide and iron manganese oxide nanoparticles from bimetallic pivalate clusters. Chem Mater 26:999\u20131013","journal-title":"Chem Mater"},{"key":"5_CR33","doi-asserted-by":"publisher","first-page":"10278","DOI":"10.1021\/la0491908","volume":"20","author":"X Liu","year":"2004","unstructured":"Liu X, Guan Y, Ma Z et al (2004) Surface modification and characterization of magnetic polymer nanospheres prepared by miniemulsion polymerization. Langmuir 20:10278\u201310282","journal-title":"Langmuir"},{"key":"5_CR34","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.jmmm.2005.11.003","volume":"303","author":"V Salgueiri\u00f1o-Maceira","year":"2006","unstructured":"Salgueiri\u00f1o-Maceira V, Correa-Duarte MA, Hucht A et al (2006) One-dimensional assemblies of silica-coated cobalt nanoparticles: Magnetic pearl necklaces. J Magn Magn Mater 303:163\u2013166","journal-title":"J Magn Magn Mater"},{"key":"5_CR35","doi-asserted-by":"publisher","first-page":"225601","DOI":"10.1088\/0957-4484\/23\/22\/225601","volume":"23","author":"R Mendoza-Resendez","year":"2012","unstructured":"Mendoza-Resendez R, Luna C, Barriga-Castro ED et al (2012) Control of crystallite orientation and size in Fe and FeCo nanoneedles. Nanotechnology 23:225601","journal-title":"Nanotechnology"},{"key":"5_CR36","doi-asserted-by":"publisher","first-page":"5046","DOI":"10.1002\/pmic.200900033","volume":"9","author":"J Tang","year":"2009","unstructured":"Tang J, Liu Y, Qi D et al (2009) On-plate-selective enrichment of glycopeptides using boronic acid-modified gold nanoparticles for direct MALDI-QIT-TOF MS analysis. Proteomics 9:5046\u20135055","journal-title":"Proteomics"},{"key":"5_CR37","doi-asserted-by":"publisher","first-page":"2000","DOI":"10.1002\/pmic.200900377","volume":"10","author":"J Tang","year":"2010","unstructured":"Tang J, Liu Y, Yin P et al (2010) Concanavalin A-immobilized magnetic nanoparticles for selective enrichment of glycoproteins and application to glycoproteomics in hepatocelluar carcinoma cell line. Proteomics 10:2000\u20132014","journal-title":"Proteomics"},{"key":"5_CR38","doi-asserted-by":"publisher","first-page":"10895","DOI":"10.1021\/ac402332z","volume":"85","author":"ED Bodnar","year":"2013","unstructured":"Bodnar ED, Perreault H (2013) Qualitative and quantitative assessment on the use of magnetic nanoparticles for glycopeptide enrichment. Anal Chem 85:10895\u201310903","journal-title":"Anal Chem"},{"key":"5_CR39","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1002\/smll.200500387","volume":"2","author":"P-C Lin","year":"2006","unstructured":"Lin P-C, Chou P-H, Chen S-H et al (2006) Ethylene glycol-protected magnetic nanoparticles for a multiplexed immunoassay in human plasma. Small 2:485\u2013489","journal-title":"Small"},{"key":"5_CR40","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1093\/bioinformatics\/btp101","volume":"25","author":"G Bindea","year":"2009","unstructured":"Bindea G, Mlecnik B, Hackl H et al (2009) ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics 25:1091\u20131093","journal-title":"Bioinformatics"},{"key":"5_CR41","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1093\/bioinformatics\/btt019","volume":"29","author":"G Bindea","year":"2013","unstructured":"Bindea G, Galon J, Mlecnik B (2013) CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data. Bioinformatics 29:661\u2013663","journal-title":"Bioinformatics"},{"key":"5_CR42","doi-asserted-by":"publisher","first-page":"5875","DOI":"10.1002\/anie.200901566","volume":"48","author":"J Liu","year":"2009","unstructured":"Liu J, Sun Z, Deng Y et al (2009) Highly water-dispersible biocompatible magnetite particles with low cytotoxicity stabilized by citrate groups. Angew Chem Int Ed Engl 48:5875\u20135879","journal-title":"Angew Chem Int Ed Engl"},{"key":"5_CR43","doi-asserted-by":"publisher","first-page":"335601","DOI":"10.1088\/0957-4484\/19\/33\/335601","volume":"19","author":"A Bumb","year":"2008","unstructured":"Bumb A, Brechbiel MW, Choyke PL et al (2008) Synthesis and characterization of ultra-small superparamagnetic iron oxide nanoparticles thinly coated with silica. Nanotechnology 19:335601","journal-title":"Nanotechnology"},{"key":"5_CR44","doi-asserted-by":"publisher","first-page":"3401","DOI":"10.1021\/ac070195u","volume":"79","author":"P-C Lin","year":"2007","unstructured":"Lin P-C, Tseng M-C, Su A-K et al (2007) Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification. Anal Chem 79:3401\u20133408","journal-title":"Anal Chem"},{"key":"5_CR45","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/75556","volume":"25","author":"M Ashburner","year":"2000","unstructured":"Ashburner M, Ball CA, Blake JA et al (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25:25\u201329","journal-title":"Nat Genet"},{"key":"5_CR46","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1093\/nar\/30.1.42","volume":"30","author":"M Kanehisa","year":"2002","unstructured":"Kanehisa M, Goto S, Kawashima S et al (2002) The KEGG databases at GenomeNet. Nucleic Acids Res 30:42\u201346","journal-title":"Nucleic Acids Res"},{"key":"5_CR47","unstructured":"BioCarta LLC (2000) Available from http:\/\/www.biocarta.com"}],"container-title":["Methods in Molecular Biology","Clinical Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-1872-0_5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T17:58:21Z","timestamp":1747159101000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-4939-1872-0_5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,18]]},"ISBN":["9781493918713","9781493918720"],"references-count":47,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-1872-0_5","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2014,10,18]]},"assertion":[{"value":"18 October 2014","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}