{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T14:53:31Z","timestamp":1743000811567,"version":"3.40.3"},"publisher-location":"Totowa, NJ","reference-count":235,"publisher":"Humana Press","isbn-type":[{"type":"print","value":"9781627030762"},{"type":"electronic","value":"9781627030779"}],"license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012]]},"DOI":"10.1007\/978-1-62703-077-9_19","type":"book-chapter","created":{"date-parts":[[2012,9,19]],"date-time":"2012-09-19T19:46:51Z","timestamp":1348084011000},"page":"373-395","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["TRP Channels in the Genitourinary Tract"],"prefix":"10.1007","author":[{"given":"Ana","family":"Charrua","sequence":"first","affiliation":[]},{"given":"Francisco","family":"Cruz","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2012,8,2]]},"reference":[{"key":"19_CR1","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1111\/j.1464-410X.2010.09650.x","volume":"106","author":"KE Andersson","year":"2010","unstructured":"Andersson KE, Gratzke C, Hedlund P (2010) The role of the transient receptor potential (TRP) superfamily of cation-selective channels in the management of the overactive bladder. BJU Int 106:1114\u20131127","journal-title":"BJU Int"},{"key":"19_CR2","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/S0306-4522(01)00496-1","volume":"109","author":"A Avelino","year":"2002","unstructured":"Avelino A, Cruz C, Nagy I et al (2002) Vanilloid receptor 1 expression in the rat urinary tract. Neuroscience 109:787\u2013798","journal-title":"Neuroscience"},{"key":"19_CR3","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1016\/j.eururo.2004.08.007","volume":"46","author":"M Lazzeri","year":"2004","unstructured":"Lazzeri M, Vannucchi MG, Zardo C et al (2004) Immunohistochemical evidence of vanilloid receptor 1 in normal human urinary bladder. Eur Urol 46:792\u2013798","journal-title":"Eur Urol"},{"key":"19_CR4","first-page":"213","volume":"65","author":"HA Saleh","year":"2006","unstructured":"Saleh HA (2006) Vanilloid receptor type 1-immunoreactive nerves in the rat urinary bladder and primary afferent neurones: the effects of age. Folia Morphol (Warsz) 65:213\u2013220","journal-title":"Folia Morphol (Warsz)"},{"key":"19_CR5","doi-asserted-by":"publisher","first-page":"3453","DOI":"10.1172\/JCI31766","volume":"117","author":"T Gevaert","year":"2010","unstructured":"Gevaert T, Vriens J, Segal A et al (2010) Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest 117:3453\u20133462","journal-title":"J Clin Invest"},{"key":"19_CR6","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1744-8069-5-5","volume":"5","author":"DS Cao","year":"2009","unstructured":"Cao DS, Yu SQ, Premkumar LS (2009) Modulation of transient receptor potential vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C. Mol Pain 5:5\u201317","journal-title":"Mol Pain"},{"key":"19_CR7","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1369\/jhc.2008.951962","volume":"57","author":"T Yamada","year":"2009","unstructured":"Yamada T, Ugawa S, Ueda T (2009) Differential localizations of the transient receptor potential channels TRPV4 and TRPV1 in the mouse urinary bladder. J Histochem Cytochem 57:277\u2013287","journal-title":"J Histochem Cytochem"},{"key":"19_CR8","doi-asserted-by":"crossref","unstructured":"Charrua A, Cruz CD, Cruz F (2012) TRPV1 and TRPV4 antagonists have synergistic effect for treating bladder overactivity in rats. 27th Annual meeting EAU, Paris (accepted)","DOI":"10.1016\/S1569-9056(12)60362-5"},{"key":"19_CR9","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1097\/01.ju.0000134886.44065.00","volume":"172","author":"RJ Stein","year":"2004","unstructured":"Stein RJ, Santos S, Nagatomi J et al (2004) Cool (TRPM8) and hot (TRPV1) receptors in the bladder and male genital tract. J Urol 172:1151\u20131178","journal-title":"J Urol"},{"key":"19_CR10","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.eururo.2007.10.024","volume":"53","author":"T Streng","year":"2008","unstructured":"Streng T, Axelsson HE, Hedlund P et al (2008) Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder. Eur Urol 53:391\u2013399","journal-title":"Eur Urol"},{"key":"19_CR11","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.urology.2004.10.006","volume":"65","author":"Y Tsukimi","year":"2005","unstructured":"Tsukimi Y, Mizuyachi K, Yamasaki T et al (2005) Cold response of the bladder in guinea pig: involvement of transient receptor potential channel, TRPM8. Urology 65:406\u2013410","journal-title":"Urology"},{"key":"19_CR12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1471-2490-6-6","volume":"6","author":"G Mukerji","year":"2006","unstructured":"Mukerji G, Yiangou Y, Corcoran SL et al (2006) Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations. BMC Urol 6:6\u201316","journal-title":"BMC Urol"},{"key":"19_CR13","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.neures.2009.07.005","volume":"65","author":"T Hayashi","year":"2009","unstructured":"Hayashi T, Kondo T, Ishimatsu M et al (2009) Expression of the TRPM8-immunoreactivity in dorsal root ganglion neurons innervating the rat urinary bladder. Neurosci Res 65:245\u2013251","journal-title":"Neurosci Res"},{"key":"19_CR14","doi-asserted-by":"publisher","first-page":"F692","DOI":"10.1152\/ajprenal.00599.2009","volume":"298","author":"W Everaerts","year":"2010","unstructured":"Everaerts W, Vriens J, Owsianik G et al (2010) Functional characterization of transient receptor potential channels in mouse urothelial cells. Am J Physiol Renal Physiol 298:F692\u2013F701","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR15","doi-asserted-by":"publisher","first-page":"13396","DOI":"10.1073\/pnas.231243698","volume":"98","author":"LA Birder","year":"2001","unstructured":"Birder LA, Kanai AJ, de Groat WC et al (2001) Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells. Proc Natl Acad Sci USA 98:13396\u201313401","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR16","doi-asserted-by":"publisher","first-page":"2944","DOI":"10.1016\/j.juro.2009.08.022","volume":"182","author":"A Charrua","year":"2009","unstructured":"Charrua A, Reguenga C, Cordeiro JM et al (2009) Functional transient receptor potential vanilloid 1 is expressed in human urothelial cells. J Urol 182:2944\u20132950","journal-title":"J Urol"},{"key":"19_CR17","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1124\/jpet.107.125435","volume":"323","author":"L Birder","year":"2007","unstructured":"Birder L, Kullmann FA, Lee H et al (2007) Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat. J Pharmacol Exp Ther 323:227\u2013235","journal-title":"J Pharmacol Exp Ther"},{"key":"19_CR18","doi-asserted-by":"publisher","first-page":"F892","DOI":"10.1152\/ajprenal.90718.2008","volume":"296","author":"FA Kullmann","year":"2009","unstructured":"Kullmann FA, Shah MA, Birder LA et al (2009) Functional TRP and ASIC-like channels in cultured urothelial cells from the rat. Am J Physiol Renal Physiol 296:F892\u2013F901","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR19","doi-asserted-by":"publisher","first-page":"F49","DOI":"10.1152\/ajprenal.00349.2010","volume":"300","author":"W Yu","year":"2010","unstructured":"Yu W, Hill WG, Apodaca G et al (2010) Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium. Am J Physiol Renal Physiol 300:F49\u2013F59","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR20","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.juro.2011.04.107","volume":"186","author":"DA Janssen","year":"2011","unstructured":"Janssen DA, Hoenderop JG, Jansen KC et al (2011) The mechanoreceptor TRPV4 is localized in adherence junctions of the human bladder urothelium: a morphological study. J Urol 186:1121\u20131127","journal-title":"J Urol"},{"key":"19_CR21","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.eururo.2007.10.016","volume":"54","author":"S Caprodossi","year":"2008","unstructured":"Caprodossi S, Lucciarini R, Amantini C et al (2008) Transient receptor potential vanilloid type 2 (TRPV2) expression in normal urothelium and in urothelial carcinoma of human bladder: correlation with the pathologic stage. Eur Urol 54:612\u2013620","journal-title":"Eur Urol"},{"key":"19_CR22","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1124\/jpet.108.139295","volume":"326","author":"KS Thorneloe","year":"2008","unstructured":"Thorneloe KS, Sulpizio AC, Lin Z et al (2008) N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: part I. J Pharmacol Exp Ther 326:432\u2013442","journal-title":"J Pharmacol Exp Ther"},{"key":"19_CR23","doi-asserted-by":"publisher","first-page":"1746","DOI":"10.1111\/j.1464-410X.2009.08658.x","volume":"104","author":"H Kobayashi","year":"2009","unstructured":"Kobayashi H, Yoshiyama M, Zakoji H et al (2009) Sex differences in the expression profile of acid-sensing ion channels in the mouse urinary bladder: a possible involvement in irritative bladder symptoms. BJU Int 104:1746\u20131751","journal-title":"BJU Int"},{"key":"19_CR24","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1038\/nn902","volume":"5","author":"LA Birder","year":"2002","unstructured":"Birder LA, Nakamura Y, Kiss S et al (2002) Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nat Neurosci 5:856\u2013860","journal-title":"Nat Neurosci"},{"key":"19_CR25","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1016\/j.juro.2006.11.046","volume":"177","author":"A Charrua","year":"2007","unstructured":"Charrua A, Cruz CD, Cruz F et al (2007) Transient receptor potential vanilloid subfamily 1 is essential for the generation of noxious bladder input and bladder overactivity in cystitis. J Urol 177:1537\u20131541","journal-title":"J Urol"},{"key":"19_CR26","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.juro.2008.08.121","volume":"181","author":"A Charrua","year":"2009","unstructured":"Charrua A, Cruz CD, Narayanan S et al (2009) GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models. J Urol 181:379\u2013386","journal-title":"J Urol"},{"key":"19_CR27","doi-asserted-by":"crossref","unstructured":"Charrua A, Boudes M, De Ridder D, Cruz CD, Cruz F (2012) TRPV1 and TRPV4 expression in bladder neurons during normal condition and during cystitis. 27th Annual meeting EAU, Paris (accepted)","DOI":"10.1016\/S1569-9056(12)60363-7"},{"key":"19_CR28","doi-asserted-by":"publisher","first-page":"F803","DOI":"10.1152\/ajprenal.90269.2008","volume":"295","author":"ES Lashinger","year":"2008","unstructured":"Lashinger ES, Steiginga MS, Hieble JP et al (2008) AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome. Am J Physiol Renal Physiol 295:F803\u2013F810","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR29","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1038\/nature719","volume":"416","author":"DD McKemy","year":"2002","unstructured":"McKemy DD, Neuhausser WM, Julius D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52\u201358","journal-title":"Nature"},{"key":"19_CR30","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/S0092-8674(02)00652-9","volume":"108","author":"AM Peier","year":"2002","unstructured":"Peier AM, Moqrich A, Hergarden AC et al (2002) A TRP channel that senses cold stimuli and menthol. Cell 108:705\u2013715","journal-title":"Cell"},{"key":"19_CR31","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1097\/WNR.0b013e3283424c9c","volume":"22","author":"Y Shibata","year":"2011","unstructured":"Shibata Y, Ugawa S, Imura M et al (2011) TRPM8-expressing dorsal root ganglion neurons project dichotomizing axons to both skin and bladder in rats. Neuroreport 22:61\u201367","journal-title":"Neuroreport"},{"key":"19_CR32","doi-asserted-by":"publisher","first-page":"F688","DOI":"10.1152\/ajprenal.00133.2008","volume":"295","author":"GP Sui","year":"2008","unstructured":"Sui GP, Wu C, Roosen A et al (2008) Modulation of bladder myofibroblast activity: implications for bladder function. Am J Physiol Renal Physiol 295:F688\u2013F697","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR33","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1016\/0140-6736(92)91186-C","volume":"339","author":"CJ Fowler","year":"1992","unstructured":"Fowler CJ, Jewkes D, McDonald WI et al (1992) Intravesical capsaicin for neurogenic bladder dysfunction. Lancet 339:1239","journal-title":"Lancet"},{"key":"19_CR34","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/S0022-5347(01)65211-X","volume":"157","author":"F Cruz","year":"1997","unstructured":"Cruz F, Guimar\u00e3es M, Silva C et al (1997) Desensitization of bladder sensory fibers by intravesical capsaicin has long lasting clinical and urodynamic effects in patients with hyperactive or hypersensitive bladder dysfunction. J Urol 157:585\u2013589","journal-title":"J Urol"},{"key":"19_CR35","doi-asserted-by":"publisher","first-page":"1825","DOI":"10.1016\/S0022-5347(01)66793-4","volume":"154","author":"G Geirsson","year":"1995","unstructured":"Geirsson G, Fall M, Sullivan L (1995) Clinical and urodynamic effects of intravesical capsaicin treatment in patients with chronic traumatic spinal detrusor hyperreflexia. J Urol 154:1825\u20131829","journal-title":"J Urol"},{"key":"19_CR36","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1080\/10790268.1996.11719431","volume":"19","author":"A Das","year":"1996","unstructured":"Das A, Chancellor MB, Watanabe T et al (1996) Intravesical capsaicin in neurologic impaired patients with detrusor hyperreflexia. J Spinal Cord Med 19:190\u2013193","journal-title":"J Spinal Cord Med"},{"key":"19_CR37","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1002\/(SICI)1520-6777(1998)17:5<513::AID-NAU7>3.0.CO;2-G","volume":"17","author":"M De S\u00e9ze","year":"1998","unstructured":"De S\u00e9ze M, Wiart L, Joseph PA et al (1998) Capsaicin and neurogenic detrusor hyperreflexia. A double blind placebo controlled study in 20 patients with spinal cord lesions. Neurourol Urodyn 17:513\u2013523","journal-title":"Neurourol Urodyn"},{"key":"19_CR38","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1080\/003655998750015287","volume":"32","author":"M Lazzeri","year":"1998","unstructured":"Lazzeri M, Spinelli M, Beneforti P et al (1998) Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord diseases. Scand J Urol Nephrol 32:331\u2013334","journal-title":"Scand J Urol Nephrol"},{"key":"19_CR39","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1046\/j.1464-410X.2003.04441.x","volume":"92","author":"HC Kuo","year":"2003","unstructured":"Kuo HC (2003) Effectiveness of intravesical resiniferatoxin in treating detrusor hyper-reflexia and external sphincter dyssynergia in patients with chronic spinal cord lesions. BJU Int 92:597\u2013601","journal-title":"BJU Int"},{"key":"19_CR40","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.eururo.2005.04.012","volume":"48","author":"C Silva","year":"2005","unstructured":"Silva C, Silva J, Ribeiro MJ (2005) Urodynamic effect of intravesical resiniferatoxin in patients with neurogenic detrusor overactivity of spinal origin: results of a double-blind randomized placebo-controlled trial. Eur Urol 48:650\u2013655","journal-title":"Eur Urol"},{"key":"19_CR41","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1111\/j.1464-410X.2005.05458.x","volume":"95","author":"HC Kuo","year":"2005","unstructured":"Kuo HC (2005) Multiple intravesical instillation of low-dose resiniferatoxin is effective in the treatment of detrusor overactivity refractory to anticholinergics. BJU Int 95:1023\u20131027","journal-title":"BJU Int"},{"key":"19_CR42","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/S0022-5347(01)63020-9","volume":"160","author":"TC Chai","year":"1998","unstructured":"Chai TC, Gray ML, Steers W (1998) The incidence of a positive ice water test in bladder outlet obstructed patients: evidence for bladder neural plasticity. J Urol 160:34\u201338","journal-title":"J Urol"},{"key":"19_CR43","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1136\/jnnp.57.2.169","volume":"57","author":"CJ Fowler","year":"1994","unstructured":"Fowler CJ, Beck RO, Gerrard S et al (1994) Intravesical capsaicin for treatment of detrusor hyperreflexia. J Neurol Neurosurg Psychiatry 57:169\u2013173","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"19_CR44","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1016\/S0022-5347(01)68162-X","volume":"158","author":"D De Ridder","year":"1997","unstructured":"De Ridder D, Chandiramani V, Dasgupta P et al (1997) Intravesical capsaicin as a treatment for refractory detrusor hyperreflexia: a dual center study with long-term followup. J Urol 158:2087\u20132092","journal-title":"J Urol"},{"key":"19_CR45","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/S0140-6736(05)63330-2","volume":"350","author":"F Cruz","year":"1997","unstructured":"Cruz F, Guimar\u00e3es M, Silva C et al (1997) Supression of bladder hyperreflexia by intravesical resiniferatoxin. Lancet 350:640\u2013641","journal-title":"Lancet"},{"key":"19_CR46","doi-asserted-by":"publisher","first-page":"2093","DOI":"10.1016\/S0022-5347(01)68164-3","volume":"158","author":"M Lazzeri","year":"1997","unstructured":"Lazzeri M, Beneforti P, Turini D (1997) Urodynamic effects of intravesical resiniferatoxin in humans: preliminary results in stable and unstable detrusor. J Urol 158:2093\u20132096","journal-title":"J Urol"},{"key":"19_CR47","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.juro.2006.03.087","volume":"176","author":"HC Kuo","year":"2006","unstructured":"Kuo HC, Liu HT, Yang WC (2006) Therapeutic effect of multiple resiniferatoxin intravesical instillations in patients with refractory detrusor overactivity: a randomized, double-blind, placebo controlled study. J Urol 176:641\u2013645","journal-title":"J Urol"},{"key":"19_CR48","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1159\/000020322","volume":"38","author":"C Silva","year":"2000","unstructured":"Silva C, Rio ME, Cruz F (2000) Desensitization of bladder sensory fibers by intravesical resiniferatoxin, a capsaicin analog: long-term results for the treatment of detrusor hyperreflexia. Eur Urol 38:444\u2013452","journal-title":"Eur Urol"},{"key":"19_CR49","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1097\/01.ju.0000169481.42259.54","volume":"174","author":"A Apostolidis","year":"2005","unstructured":"Apostolidis A, Popat R, Yiangou Y et al (2005) Decreased sensory receptors P2X3 and TRPV1 in suburothelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity. J Urol 174:977\u2013982, discussion 982\u2013983","journal-title":"J Urol"},{"key":"19_CR50","first-page":"7","volume":"11","author":"C Silva","year":"2007","unstructured":"Silva C, Silva J, Castro H et al (2007) Bladder sensory desensitization decreases urinary urgency. BMC Urol 11:7\u20139","journal-title":"BMC Urol"},{"key":"19_CR51","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S0022-5347(05)64683-6","volume":"168","author":"C Silva","year":"2002","unstructured":"Silva C, Ribeiro MJ, Cruz F (2002) The effect of intravesical resiniferatoxin in patients with idiopathic detrusor instability suggests that involuntary detrusor contractions are triggered by C-fiber input. J Urol 168:575\u2013579","journal-title":"J Urol"},{"key":"19_CR52","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1097\/01.ju.0000081652.31524.27","volume":"170","author":"HC Kuo","year":"2003","unstructured":"Kuo HC (2003) Effectiveness of intravesical resiniferatoxin for anticholinergic treatment refractory detrusor overactivity due to nonspinal cord lesions. J Urol 170:835\u2013839","journal-title":"J Urol"},{"key":"19_CR53","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.eururo.2004.01.016","volume":"46","author":"P Dinis","year":"2004","unstructured":"Dinis P, Silva J, Ribeiro MJ et al (2004) Bladder C-fiber desensitization induces a long-lasting improvement of BPH-associated storage LUTS: a pilot study. Eur Urol 46:88\u201393","journal-title":"Eur Urol"},{"key":"19_CR54","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/S0022-5347(05)67279-5","volume":"164","author":"M Lazzeri","year":"2000","unstructured":"Lazzeri M, Beneforti M, Spinelli A et al (2000) Intravesical resiniferatoxin for the treatment of hypersensitive disorder: a randomized placebo controlled study. J Urol 164:676\u2013679","journal-title":"J Urol"},{"key":"19_CR55","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1016\/j.eururo.2006.04.006","volume":"50","author":"A Apostolidis","year":"2006","unstructured":"Apostolidis A, Gonzales GE, Fowler CJ (2006) Effect of intravesical resiniferatoxin (RTX) on lower urinary tract symptoms, urodynamic parameters, and quality of life of patients with urodynamic increased bladder sensation. Eur Urol 50:1299\u20131305","journal-title":"Eur Urol"},{"key":"19_CR56","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.juro.2006.03.074","volume":"176","author":"G Mukerji","year":"2006","unstructured":"Mukerji G, Yiangou Y, Agarwal SK et al (2006) Transient receptor potential vanilloid receptor subtype 1 in painful bladder syndrome and its correlation with pain. J Urol 176:797\u2013801","journal-title":"J Urol"},{"key":"19_CR57","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s00192-005-1307-4","volume":"16","author":"TY Chen","year":"2005","unstructured":"Chen TY, Corcos J, Camel M et al (2005) Prospective, randomized, double-blind study of safety and tolerability of intravesical resiniferatoxin (RTX) in interstitial cystitis (IC). Int Urogynecol J Pelvic Floor Dysfunct 16:293\u2013297","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"key":"19_CR58","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1159\/000096940","volume":"78","author":"CH Peng","year":"2007","unstructured":"Peng CH, Kuo HC (2007) Multiple intravesical instillations of low-dose resiniferatoxin in the treatment of refractory interstitial cystitis. Urol Int 78:78\u201381","journal-title":"Urol Int"},{"key":"19_CR59","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1097\/01.ju.0000154631.92150.ef","volume":"173","author":"CK Payne","year":"2005","unstructured":"Payne CK, Mosbaugh PG, Forrest JB et al (2005) Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo controlled trial. J Urol 173:1590\u20131594","journal-title":"J Urol"},{"key":"19_CR60","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1002\/nau.20326","volume":"26","author":"L Liu","year":"2007","unstructured":"Liu L, Mansfield KJ, Kristiana I et al (2007) The molecular basis of urgency: regional difference of vanilloid receptor expression in the human urinary bladder. Neurourol Urodyn 26:433\u2013438","journal-title":"Neurourol Urodyn"},{"key":"19_CR61","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/S0161-813X(03)00146-3","volume":"24","author":"RM Caudle","year":"2003","unstructured":"Caudle RM, Karai L, Mena N et al (2003) Resiniferatoxin-induced loss of plasma membrane in vanilloid receptor expressing cells. Neurotoxicology 24:895\u2013908","journal-title":"Neurotoxicology"},{"key":"19_CR62","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1007\/BF02975122","volume":"27","author":"SY Lee","year":"2004","unstructured":"Lee SY, Hong Y, Oh U (2004) Decreased pain sensitivity of capsaicin-treated rats results from decreased VR1 expression. Arch Pharm Res 27:1154\u20131160","journal-title":"Arch Pharm Res"},{"key":"19_CR63","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.autneu.2011.09.005","volume":"166","author":"A Santos-Silva","year":"2012","unstructured":"Santos-Silva A, Charrua A, Cruz CD et al (2012) Rat detrusor overactivity induced by chronic spinalization can be abolished by a transient receptor potential vanilloid 1 (TRPV1) antagonist. Auton Neurosci 166:35\u201338","journal-title":"Auton Neurosci"},{"key":"19_CR64","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1111\/j.1464-410X.2003.04722.x","volume":"93","author":"CM Brady","year":"2004","unstructured":"Brady CM, Apostolidis AN, Harper M et al (2004) Parallel changes in bladder suburothelial vanilloid receptor TRPV1 and pan-neuronal marker PGP9.5 immunoreactivity in patients with neurogenic detrusor overactivity after intravesical resiniferatoxin treatment. BJU Int 93:770\u2013776","journal-title":"BJU Int"},{"key":"19_CR65","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1002\/jnr.21844","volume":"87","author":"X Xu","year":"2009","unstructured":"Xu X, Wang P, Zou X et al (2009) Increases in transient receptor potential vanilloid-1 mRNA and protein in primary afferent neurons stimulated by protein kinase C and their possible role in neurogenic inflammation. J Neurosci Res 87:482\u2013494","journal-title":"J Neurosci Res"},{"key":"19_CR66","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0896-6273(02)00908-X","volume":"36","author":"RR Ji","year":"2002","unstructured":"Ji RR, Samad TA, Jin SX et al (2002) p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36:57\u201368","journal-title":"Neuron"},{"key":"19_CR67","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/j.1471-4159.2006.04363.x","volume":"101","author":"Q Xue","year":"2007","unstructured":"Xue Q, Jong B, Chen T et al (2007) Transcription of rat TRPV1 utilizes a dual promoter system that is positively regulated by nerve growth factor. J Neurochem 101:212\u2013222","journal-title":"J Neurochem"},{"key":"19_CR68","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/S0022-5347(01)61915-3","volume":"161","author":"AJ Okragly","year":"1999","unstructured":"Okragly AJ, Niles AL, Saban R, Schmidt D, Hoffman RL, Warner TF, Moon TD, Uehling DT, Haak-Frendscho M (1999) Elevated tryptase, nerve growth factor, neurotrophin-3 and glial cell line-derived neurotrophic factor levels in the urine of interstitial cystitis and bladder cancer patients. J Urol 161:438\u2013441","journal-title":"J Urol"},{"key":"19_CR69","doi-asserted-by":"publisher","first-page":"1773","DOI":"10.1016\/S0022-5347(05)00992-4","volume":"151","author":"JC Kim","year":"2006","unstructured":"Kim JC, Park EY, Seo SI, Park YH, Hwang TK (2006) Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder. J Urol 151:1773\u20131776","journal-title":"J Urol"},{"key":"19_CR70","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1016\/S0022-5347(06)00258-8","volume":"151","author":"A Giannantoni","year":"2006","unstructured":"Giannantoni A, Di Stasi SM, Nardicchi V, Zucchi A, Macchioni L, Bini V, Goracci G, Porena M (2006) Botulinum-A toxin injections into the detrusor muscle decrease nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity. J Urol 151:2341\u20132344","journal-title":"J Urol"},{"key":"19_CR71","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1111\/j.1464-410X.2008.07757.x","volume":"102","author":"HT Liu","year":"2008","unstructured":"Liu HT, Chancellor MB, Kuo HC (2008) Urinary nerve growth factor level could be a biomarker in the differential diagnosis of mixed urinary incontinence in women. BJU Int 102:1440\u20131444","journal-title":"BJU Int"},{"key":"19_CR72","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/j.eururo.2008.04.037","volume":"56","author":"HT Liu","year":"2009","unstructured":"Liu HT, Chancellor MB, Kuo HC (2009) Urinary nerve growth factor levels are elevated in patients with detrusor overactivity and decreased in responders to detrusor botulinum toxin-A injection. Eur Urol 56:700\u2013706","journal-title":"Eur Urol"},{"key":"19_CR73","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1085\/jgp.200609576","volume":"128","author":"AT Stein","year":"2006","unstructured":"Stein AT, Ufret-Vincenty CA, Hua L et al (2006) Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol 128:509\u2013522","journal-title":"J Gen Physiol"},{"key":"19_CR74","doi-asserted-by":"publisher","first-page":"2756","DOI":"10.1074\/jbc.275.4.2756","volume":"275","author":"MA Schumacher","year":"2000","unstructured":"Schumacher MA, Moff I, Sudanagunta SP et al (2000) Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem 275:2756\u20132762","journal-title":"J Biol Chem"},{"issue":"4","key":"19_CR75","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1124\/mol.104.009852","volume":"67","author":"G Lu","year":"2005","unstructured":"Lu G, Henderson D, Liu L, Reinhart PH, Simon SA (2005) TRPV1b, a functional human vanilloid receptor splice variant. Mol Pharmacol 67(4):1119\u20131127","journal-title":"Mol Pharmacol"},{"key":"19_CR76","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1097\/WNR.0b013e32830f1e73","volume":"19","author":"A Charrua","year":"2008","unstructured":"Charrua A, Reguenga C, Paule CC et al (2008) Cystitis is associated with TRPV1b-downregulation in rat dorsal root ganglia. Neuroreport 19:1469\u20131472","journal-title":"Neuroreport"},{"key":"19_CR77","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/22761","volume":"400","author":"PM Zygmunt","year":"1999","unstructured":"Zygmunt PM, Petersson J, Andersson DA et al (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400:452\u2013457","journal-title":"Nature"},{"key":"19_CR78","doi-asserted-by":"publisher","first-page":"8400","DOI":"10.1073\/pnas.122196999","volume":"99","author":"SM Huang","year":"2002","unstructured":"Huang SM, Bisogno T, Trevisani M et al (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA 99:8400\u20138405","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR79","doi-asserted-by":"publisher","first-page":"13633","DOI":"10.1074\/jbc.M211231200","volume":"278","author":"CJ Chu","year":"2003","unstructured":"Chu CJ, Huang SM, De Petrocellis L et al (2003) N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J Biol Chem 278:13633\u201313639","journal-title":"J Biol Chem"},{"key":"19_CR80","doi-asserted-by":"publisher","first-page":"6155","DOI":"10.1073\/pnas.97.11.6155","volume":"97","author":"SW Hwang","year":"2000","unstructured":"Hwang SW, Cho H, Kwak J et al (2000) Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci USA 97:6155\u20136160","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR81","doi-asserted-by":"publisher","first-page":"11253","DOI":"10.1523\/JNEUROSCI.2657-04.2004","volume":"24","author":"P Dinis","year":"2004","unstructured":"Dinis P, Charrua A, Avelino A et al (2004) Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis. J Neurosci 24:11253\u201311263","journal-title":"J Neurosci"},{"key":"19_CR82","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/BF02977669","volume":"28","author":"SY Lee","year":"2005","unstructured":"Lee SY, Lee JH, Kang KK et al (2005) Sensitization of vanilloid receptor involves an increase in the phosphorylated form of the channel. Arch Pharm Res 28:405\u2013412","journal-title":"Arch Pharm Res"},{"key":"19_CR83","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.neulet.2005.01.080","volume":"381","author":"A Sculptoreanu","year":"2005","unstructured":"Sculptoreanu A, de Groat WC, Buffington CA et al (2005) Protein kinase C contributes to abnormal capsaicin responses in DRG neurons from cats with feline interstitial cystitis. Neurosci Lett 381:42\u201346","journal-title":"Neurosci Lett"},{"key":"19_CR84","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.1111\/j.1432-1033.2004.04082.x","volume":"271","author":"DN Cortright","year":"2004","unstructured":"Cortright DN, Szallasi A (2004) Biochemical pharmacology of the vanilloid receptor TRPV1. An update. Eur J Biochem 271:1814\u20131819","journal-title":"Eur J Biochem"},{"key":"19_CR85","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1002\/nau.21045","volume":"30","author":"M Li","year":"2011","unstructured":"Li M, Sun Y, Simard JM et al (2011) Increased transient receptor potential vanilloid type 1 (TRPV1) signaling in idiopathic overactive bladder urothelial cells. Neurourol Urodyn 30:606\u2013611","journal-title":"Neurourol Urodyn"},{"key":"19_CR86","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.urology.2004.10.007","volume":"65","author":"A Apostolidis","year":"2005","unstructured":"Apostolidis A, Brady CM, Yiangou Y et al (2005) Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin. Urology 65:400\u2013405","journal-title":"Urology"},{"key":"19_CR87","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/j.molmed.2006.09.001","volume":"12","author":"A Szallasi","year":"2006","unstructured":"Szallasi A, Cruz F, Geppetti P (2006) TRPV1: a therapeutic target for novel analgesic drugs? Trends Mol Med 12:545\u2013554","journal-title":"Trends Mol Med"},{"key":"19_CR88","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1113\/jphysiol.1970.sp009027","volume":"206","author":"A Jancs\u00f3-Gabor","year":"1970","unstructured":"Jancs\u00f3-Gabor A, Szolcsanyi J, Jancso N (1970) Irreversible impairment of thermoregulation induced by capsaicin and similar pungent substances in rats and guinea-pigs. J Physiol 206:495\u2013507","journal-title":"J Physiol"},{"key":"19_CR89","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1021\/jm0495071","volume":"48","author":"DM Swanson","year":"2005","unstructured":"Swanson DM, Dubin AE, Shah C et al (2005) Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist. J Med Chem 48:1857\u20131872","journal-title":"J Med Chem"},{"key":"19_CR90","doi-asserted-by":"publisher","first-page":"R37","DOI":"10.1152\/ajpregu.00668.2006","volume":"292","author":"AA Romanovsky","year":"2007","unstructured":"Romanovsky AA (2007) Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system. Am J Physiol Regul Integr Comp Physiol 292:R37\u2013R46","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"19_CR91","doi-asserted-by":"publisher","first-page":"7459","DOI":"10.1523\/JNEUROSCI.1483-07.2007","volume":"27","author":"AA Steiner","year":"2007","unstructured":"Steiner AA, Turek VF, Almeida MC et al (2007) Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors. J Neurosci 27:7459\u20137468","journal-title":"J Neurosci"},{"key":"19_CR92","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1016\/j.tips.2008.08.003","volume":"29","author":"NR Gavva","year":"2008","unstructured":"Gavva NR (2008) Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1. Trends Pharmacol Sci 29:550\u2013557","journal-title":"Trends Pharmacol Sci"},{"key":"19_CR93","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.pain.2008.01.024","volume":"136","author":"NR Gavva","year":"2008","unstructured":"Gavva NR, Treanor JJ, Garami A et al (2008) Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans. Pain 136:202\u2013210","journal-title":"Pain"},{"key":"19_CR94","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.brainresrev.2008.12.006","volume":"60","author":"GY Wong","year":"2008","unstructured":"Wong GY, Gavva NR (2008) Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: recent advances and setbacks. Brain Res Rev 60:267\u2013277","journal-title":"Brain Res Rev"},{"key":"19_CR95","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nrd2280","volume":"6","author":"A Szallasi","year":"2007","unstructured":"Szallasi A, Cortright DN, Blum CA et al (2007) The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 6:357\u2013372","journal-title":"Nat Rev Drug Discov"},{"key":"19_CR96","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1097\/HJH.0b013e328333af48","volume":"28","author":"W Huang","year":"2010","unstructured":"Huang W, Rubinstein J, Prieto AR et al (2010) Enhanced postmyocardial infarction fibrosis via stimulation of the transforming growth factor-beta-Smad2 signaling pathway: role of transient receptor potential vanilloid type 1 channels. J Hypertens 28:367\u2013376","journal-title":"J Hypertens"},{"key":"19_CR97","doi-asserted-by":"publisher","first-page":"19084","DOI":"10.1073\/pnas.1005333107","volume":"107","author":"W Everaerts","year":"2010","unstructured":"Everaerts W, Zhen X, Ghosh D et al (2010) Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci USA 107:19084\u201319089","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR98","first-page":"12","volume":"28","author":"T Miyamoto","year":"2009","unstructured":"Miyamoto T, Mochizuki T, Zakohji H et al (2009) The expression of transient receptor potential (TRP) V4, A1, and V1 in the human bladder mucosa of normal and bladder outlet obstruction \u2013 a novel mechanism in the obstruction-induced bladder overactivity. Neurourol Urodyn 28:12","journal-title":"Neurourol Urodyn"},{"key":"19_CR99","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.bcp.2006.04.003","volume":"72","author":"AE Lemos","year":"2006","unstructured":"Lemos AE, Ferreira J, Andr\u00e9 E et al (2006) Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder. Biochem Pharmacol 72:104\u2013114","journal-title":"Biochem Pharmacol"},{"key":"19_CR100","doi-asserted-by":"publisher","first-page":"F1223","DOI":"10.1152\/ajprenal.00535.2010","volume":"300","author":"EL Andrade","year":"2011","unstructured":"Andrade EL, Forner S, Bento AF et al (2011) TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury. Am J Physiol Renal Physiol 300:F1223\u2013F1234","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR101","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1016\/j.pain.2011.01.049","volume":"152","author":"J Chen","year":"2011","unstructured":"Chen J, Joshi SK, DiDomenico S et al (2011) Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation. Pain 152:1165\u20131172","journal-title":"Pain"},{"key":"19_CR102","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.urology.2007.11.127","volume":"72","author":"S Du","year":"2008","unstructured":"Du S, Akari I, Kobayashi H et al (2008) Differential expression profile of cold (TRPA1) and cool (TRPM8) receptors in human urogenital organs. Urology 72:450\u2013455","journal-title":"Urology"},{"key":"19_CR103","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.autneu.2011.05.006","volume":"164","author":"T Hayashi","year":"2011","unstructured":"Hayashi T, Kondo T, Ishimatsu M et al (2011) Function and expression pattern of TRPM8 in bladder afferent neurons associated with bladder outlet obstruction in rats. Auton Neurosci 164:27\u201333","journal-title":"Auton Neurosci"},{"key":"19_CR104","doi-asserted-by":"publisher","first-page":"7048","DOI":"10.1074\/jbc.M311448200","volume":"279","author":"J Jung","year":"2004","unstructured":"Jung J, Shin JS, Lee SY et al (2004) Phosphorylation of vanilloid receptor 1 by Ca2+\/calmodulin-dependent kinase II regulates its vanilloid binding. J Biol Chem 279:7048\u20137054","journal-title":"J Biol Chem"},{"key":"19_CR105","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1113\/jphysiol.2006.111534","volume":"575","author":"S Amadesi","year":"2006","unstructured":"Amadesi S, Cottrell GS, Divino L et al (2006) Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice. J Physiol 575:555\u2013571","journal-title":"J Physiol"},{"key":"19_CR106","doi-asserted-by":"publisher","first-page":"4300","DOI":"10.1523\/JNEUROSCI.5679-03.2004","volume":"24","author":"S Amadesi","year":"2004","unstructured":"Amadesi S, Nie J, Vergnolle N et al (2004) Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci 24:4300\u20134312","journal-title":"J Neurosci"},{"key":"19_CR107","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1113\/jphysiol.2006.112250","volume":"576","author":"T Ohta","year":"2006","unstructured":"Ohta T, Ikemi Y, Murakami M et al (2006) Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-HT receptors in rat primary sensory neurons. J Physiol 576:809\u2013822","journal-title":"J Physiol"},{"key":"19_CR108","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1097\/01.ju.0000143191.55468.1d","volume":"173","author":"A Dattilio","year":"2005","unstructured":"Dattilio A, Vizzard MA (2005) Up-regulation of protease activated receptors in bladder after cyclophosphamide induced cystitis and colocalization with capsaicin receptor (VR1) in bladder nerve fibers. J Urol 173:635\u2013639","journal-title":"J Urol"},{"key":"19_CR109","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.brainres.2008.10.066","volume":"1248","author":"SM Carlton","year":"2009","unstructured":"Carlton SM, Du J, Zhou S (2009) Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function. Brain Res 1248:86\u201395","journal-title":"Brain Res"},{"key":"19_CR110","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/1744-8069-2-22","volume":"2","author":"I Vetter","year":"2006","unstructured":"Vetter I, Wyse BD, Monteith GR et al (2006) The mu opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway. Mol Pain 2:22\u201337","journal-title":"Mol Pain"},{"key":"19_CR111","doi-asserted-by":"publisher","first-page":"19540","DOI":"10.1074\/jbc.M707865200","volume":"283","author":"I Vetter","year":"2008","unstructured":"Vetter I, Cheng W, Peiris M et al (2008) Rapid, opioid-sensitive mechanisms involved in transient receptor potential vanilloid 1 sensitization. J Biol Chem 283:19540\u201319550","journal-title":"J Biol Chem"},{"key":"19_CR112","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.neulet.2007.04.002","volume":"420","author":"M Yoshiyama","year":"2007","unstructured":"Yoshiyama M, de Groat WC (2007) Role of spinal metabotropic glutamate receptors in regulation of lower urinary tract function in the decerebrate unanesthetized rat. Neurosci Lett 420:18\u201322","journal-title":"Neurosci Lett"},{"key":"19_CR113","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S0090-4295(01)01637-5","volume":"59","author":"KE Andersson","year":"2002","unstructured":"Andersson KE (2002) Bladder activation: afferent mechanisms. Urology 59:43\u201350","journal-title":"Urology"},{"key":"19_CR114","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.eururo.2009.11.042","volume":"57","author":"V Kumar","year":"2010","unstructured":"Kumar V, Chapple CR, Rosario D et al (2010) In vitro release of adenosine triphosphate from the urothelium of human bladders with detrusor overactivity, both neurogenic and idiopathic. Eur Urol 57:1087\u20131092","journal-title":"Eur Urol"},{"key":"19_CR115","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1007\/978-3-642-16499-6_22","volume":"202","author":"AP Ford","year":"2011","unstructured":"Ford AP, Cockayne DA (2011) ATP and P2X purinoceptors in urinary tract disorders. Handb Exp Pharmacol 202:485\u2013526","journal-title":"Handb Exp Pharmacol"},{"key":"19_CR116","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1016\/S0022-5347(05)65726-6","volume":"166","author":"Y Sun","year":"2001","unstructured":"Sun Y, Keay S, de Deyne PG et al (2001) Augmented stretch activated adenosine triphosphate release from bladder uroepithelial cells in patients with interstitial cystitis. J Urol 166:1951\u20131956","journal-title":"J Urol"},{"key":"19_CR117","doi-asserted-by":"publisher","first-page":"S132","DOI":"10.1038\/sj.bjp.0706637","volume":"147","author":"APDW Ford","year":"2006","unstructured":"Ford APDW, Gever JR, Nunn PA et al (2006) Purinoceptors as therapeutic targets for lower urinary tract dysfunction. Br J Pharmacol 147:S132\u2013S143","journal-title":"Br J Pharmacol"},{"key":"19_CR118","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1111\/j.1476-5381.2009.00431.x","volume":"158","author":"P Sadananda","year":"2009","unstructured":"Sadananda P, Shang F, Liu L et al (2009) Release of ATP from rat urinary bladder mucosa: role of acid, vanilloids and stretch. Br J Pharmacol 158:1655\u20131662","journal-title":"Br J Pharmacol"},{"key":"19_CR119","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1159\/000056122","volume":"63","author":"S Elneil","year":"2001","unstructured":"Elneil S, Skepper JN, Kidd EJ et al (2001) Distribution of P2X(1) and P2X(3) receptors in the rat and human urinary bladder. Pharmacology 63:120\u2013128","journal-title":"Pharmacology"},{"key":"19_CR120","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1097\/01.ju.0000099660.46774.3c","volume":"171","author":"Y Sun","year":"2004","unstructured":"Sun Y, Chai TC (2004) Up-regulation of P2X3 receptor during stretch of bladder urothelial cells from patients with interstitial cystitis. J Urol 171:448\u2013452","journal-title":"J Urol"},{"key":"19_CR121","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1111\/j.1464-410X.2004.04858.x","volume":"93","author":"HV Tempest","year":"2004","unstructured":"Tempest HV, Dixon AK, Turner WH et al (2004) P2X and P2X receptor expression in human bladder urothelium and changes in interstitial cystitis. BJU Int 93:1344\u20131348","journal-title":"BJU Int"},{"key":"19_CR122","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.neuroscience.2009.01.050","volume":"159","author":"JS Walczak","year":"2009","unstructured":"Walczak JS, Price TJ, Cervero F (2009) Cannabinoid CB1 receptors are expressed in the mouse urinary bladder and their activation modulates afferent bladder activity. Neuroscience 159:1154\u20131163","journal-title":"Neuroscience"},{"key":"19_CR123","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/1744-8069-7-31","volume":"7","author":"JS Walczak","year":"2011","unstructured":"Walczak JS, Cervero F (2011) Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents. Mol Pain 7:31","journal-title":"Mol Pain"},{"key":"19_CR124","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1038\/35050121","volume":"408","author":"LS Premkumar","year":"2000","unstructured":"Premkumar LS, Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408:985\u2013990","journal-title":"Nature"},{"key":"19_CR125","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1111\/j.1469-7793.2001.00813.x","volume":"534","author":"V Vellani","year":"2001","unstructured":"Vellani V, Mapplebeck S, Moriondo A et al (2001) Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. J Physiol 534:813\u2013825","journal-title":"J Physiol"},{"key":"19_CR126","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1152\/jn.2002.88.1.544","volume":"88","author":"T Sugiura","year":"2002","unstructured":"Sugiura T, Tominaga M, Katsuya H et al (2002) Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J Neurophysiol 88:544\u2013548","journal-title":"J Neurophysiol"},{"key":"19_CR127","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1124\/jpet.102.043422","volume":"304","author":"MJ Carr","year":"2003","unstructured":"Carr MJ, Lollarik M, Meeker SN et al (2003) A role for TRPV1 in bradykinin-induced excitation of vagal airway afferent nerve terminals. J Pharmacol Exp Ther 304:1275\u20131279","journal-title":"J Pharmacol Exp Ther"},{"key":"19_CR128","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.ejphar.2004.07.076","volume":"498","author":"HB Tang","year":"2004","unstructured":"Tang HB, Inoue A, Oshita K et al (2004) Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons. Eur J Pharmacol 498:37\u201343","journal-title":"Eur J Pharmacol"},{"key":"19_CR129","first-page":"33","volume":"25","author":"K Mizumura","year":"2005","unstructured":"Mizumura K, Sugiur T, Koda H et al (2005) Pain and bradykinin receptors-sensory transduction mechanism in the nociceptor terminals and expression change of bradykinin receptors in inflamed condition. Nihon Shinkei Seishin Yakurigaku Zasshi 25:33\u201338","journal-title":"Nihon Shinkei Seishin Yakurigaku Zasshi"},{"key":"19_CR130","doi-asserted-by":"publisher","first-page":"10150","DOI":"10.1073\/pnas.152002699","volume":"99","author":"J Shin","year":"2002","unstructured":"Shin J, Cho H, Hwang SW et al (2002) Bradykinin-12-lipoxygenase-VR1 signalling pathway for inflammatory hyperalgesia. Proc Natl Acad Sci USA 99:10150\u201310155","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR131","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1038\/sj.bjp.0705546","volume":"141","author":"J Ferreira","year":"2004","unstructured":"Ferreira J, da Silva GL, Calixto JB (2004) Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice. Br J Pharmacol 141: 787\u2013794","journal-title":"Br J Pharmacol"},{"key":"19_CR132","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.2119\/molmed.2011.00063","volume":"17","author":"Y Wang","year":"2011","unstructured":"Wang Y, Wang DH (2011) Protective Effect of TRPV1 against Renal Fibrosis via Inhibition of TGF-\u03b2\/Smad Signaling in DOCA-Salt Hypertension. Mol Med 17:1204\u20131212","journal-title":"Mol Med"},{"key":"19_CR133","doi-asserted-by":"publisher","first-page":"F1550","DOI":"10.1152\/ajprenal.00012.2009","volume":"297","author":"Y Wang","year":"2009","unstructured":"Wang Y, Wang DH (2009) Aggravated renal inflammatory responses in TRPV1 gene knockout mice subjected to DOCA-salt hypertension. Am J Physiol Renal Physiol 297:F1550\u2013F1559","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR134","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1124\/jpet.108.146241","volume":"329","author":"K Ueda","year":"2009","unstructured":"Ueda K, Tsuji F, Hirata T et al (2009) Preventive effect of SA13353 [1-[2-(1-adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea], a novel transient receptor potential vanilloid 1 agonist, on ischemia\/reperfusion-induced renal injury in rats. J Pharmacol Exp Ther 329:202\u2013209","journal-title":"J Pharmacol Exp Ther"},{"key":"19_CR135","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1124\/jpet.108.136374","volume":"325","author":"C Xie","year":"2008","unstructured":"Xie C, Sachs JR, Wang DH (2008) Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors. J Pharmacol Exp Ther 325:751\u2013757","journal-title":"J Pharmacol Exp Ther"},{"key":"19_CR136","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1161\/01.HYP.0000174603.27383.67","volume":"46","author":"Y Zhu","year":"2005","unstructured":"Zhu Y, Wang Y, Wang DH (2005) Diuresis and natriuresis caused by activation of VR1-positive sensory nerves in renal pelvis of rats. Hypertension 46:992\u2013997","journal-title":"Hypertension"},{"key":"19_CR137","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.phrs.2008.01.011","volume":"57","author":"J Li","year":"2008","unstructured":"Li J, Wang DH (2008) Increased GFR and renal excretory function by activation of TRPV1 in the isolated perfused kidney. Pharmacol Res 57:239\u2013246","journal-title":"Pharmacol Res"},{"key":"19_CR138","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1016\/j.neuroscience.2008.04.010","volume":"154","author":"T Kawamata","year":"2008","unstructured":"Kawamata T, Ji W, Yamamoto J et al (2008) Contribution of transient receptor potential vanilloid subfamily 1 to endothelin-1-induced thermal hyperalgesia. Neuroscience 154:1067\u20131076","journal-title":"Neuroscience"},{"key":"19_CR139","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1097\/FJC.0b013e318168d120","volume":"51","author":"Y Zhu","year":"2008","unstructured":"Zhu Y, Wang DH (2008) Segmental regulation of sodium and water excretion by TRPV1 activation in the kidney. J Cardiovasc Pharmacol 51:437\u2013442","journal-title":"J Cardiovasc Pharmacol"},{"key":"19_CR140","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1161\/HYPERTENSIONAHA.108.117499","volume":"53","author":"F Gao","year":"2009","unstructured":"Gao F, Sui D, Garavito RM et al (2009) Salt intake augments hypotensive effects of transient receptor potential vanilloid 4: functional significance and implication. Hypertension 53:228\u2013235","journal-title":"Hypertension"},{"key":"19_CR141","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1161\/HYPERTENSIONAHA.109.147710","volume":"55","author":"F Gao","year":"2010","unstructured":"Gao F, Wang DH (2010) Impairment in function and expression of transient receptor potential vanilloid type 4 in Dahl salt-sensitive rats: significance and mechanism. Hypertension 55:1018\u20131025","journal-title":"Hypertension"},{"key":"19_CR142","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1159\/000316528","volume":"32","author":"C Xie","year":"2010","unstructured":"Xie C, Wang DH (2010) Effects of a high-salt diet on TRPV-1-dependent renal nerve activity in Dahl salt-sensitive rats. Am J Nephrol 32:194\u2013200","journal-title":"Am J Nephrol"},{"key":"19_CR143","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1161\/HYPERTENSIONAHA.109.132167","volume":"54","author":"C Xie","year":"2009","unstructured":"Xie C, Wang DH (2009) Ablation of transient receptor potential vanilloid 1 abolishes endothelin-induced increases in afferent renal nerve activity: mechanisms and functional significance. Hypertension 54:1298\u20131305","journal-title":"Hypertension"},{"key":"19_CR144","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1159\/000107665","volume":"27","author":"Y Zhu","year":"2007","unstructured":"Zhu Y, Xie C, Wang DH (2007) TRPV1-mediated diuresis and natriuresis induced by hypertonic saline perfusion of the renal pelvis. Am J Nephrol 27:530\u2013537","journal-title":"Am J Nephrol"},{"key":"19_CR145","doi-asserted-by":"publisher","first-page":"F316","DOI":"10.1152\/ajprenal.00308.2007","volume":"294","author":"NH Feng","year":"2008","unstructured":"Feng NH, Lee HH, Shiang JC et al (2008) Transient receptor potential vanilloid type 1 channels act as mechanoreceptors and cause substance P release and sensory activation in rat kidneys. Am J Physiol Renal Physiol 294:F316\u2013F325","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR146","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1097\/01.hjh.0000249706.42230.a8","volume":"24","author":"J Li","year":"2006","unstructured":"Li J, Wang DH (2006) Differential mechanisms mediating depressor and diuretic effects of anandamide. J Hypertens 24:2271\u20132276","journal-title":"J Hypertens"},{"issue":"3","key":"19_CR147","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/S0306-4522(01)00373-6","volume":"107","author":"JF Sanchez","year":"2001","unstructured":"Sanchez JF, Krause JE, Cortright DN (2001) The distribution and regulation of vanilloid receptor VR1 and VR1 5\u2032 splice variant RNA expression in rat. Neuroscience 107(3):373\u2013381","journal-title":"Neuroscience"},{"key":"19_CR148","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1111\/j.1471-4159.2006.04145.x","volume":"99","author":"MH Vos","year":"2006","unstructured":"Vos MH, Neelands TR, McDonald HA et al (2006) TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells. J Neurochem 99:1088\u20131102","journal-title":"J Neurochem"},{"key":"19_CR149","doi-asserted-by":"publisher","first-page":"37423","DOI":"10.1074\/jbc.M407205200","volume":"279","author":"C Wang","year":"2004","unstructured":"Wang C, Hu HZ, Colton CK et al (2004) An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. J Biol Chem 279:37423\u201337430","journal-title":"J Biol Chem"},{"key":"19_CR150","doi-asserted-by":"publisher","first-page":"F117","DOI":"10.1152\/ajprenal.00143.2005","volume":"290","author":"W Tian","year":"2006","unstructured":"Tian W, Fu Y, Wang DH et al (2006) Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant. Am J Physiol Renal Physiol 290:F117\u2013F126","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR151","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1097\/WNR.0b013e328165d1a2","volume":"18","author":"H Eilers","year":"2007","unstructured":"Eilers H, Lee SY, Hau CW et al (2007) The rat vanilloid receptor splice variant VR.5\u2032sv blocks TRPV1 activation. Neuroreport 18:969\u2013973","journal-title":"Neuroreport"},{"key":"19_CR152","doi-asserted-by":"publisher","first-page":"F17","DOI":"10.1152\/ajprenal.00397.2003","volume":"287","author":"W Tian","year":"2004","unstructured":"Tian W, Salanova M, Xu H et al (2004) Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments. Am J Physiol Renal Physiol 287:F17\u2013F24","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR153","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/s00424-005-1456-9","volume":"451","author":"DM Cohen","year":"2005","unstructured":"Cohen DM (2005) TRPV4 and the mammalian kidney. Pflugers Arch 451:168\u2013175","journal-title":"Pflugers Arch"},{"key":"19_CR154","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1152\/physiolgenomics.2001.4.3.165","volume":"4","author":"NS Delany","year":"2001","unstructured":"Delany NS, Hurle M, Facer P et al (2001) Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2. Physiol Genomics 4:165\u2013174","journal-title":"Physiol Genomics"},{"key":"19_CR155","doi-asserted-by":"publisher","first-page":"F667","DOI":"10.1152\/ajprenal.00458.2005","volume":"292","author":"J Taniguchi","year":"2006","unstructured":"Taniguchi J, Tsuruoka S, Mizuno A et al (2006) TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct. Am J Physiol Renal Physiol 292:F667\u2013F673","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR156","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1023\/A:1020521308985","volume":"30","author":"M Haas","year":"1998","unstructured":"Haas M, Forbush B 3rd (1998) The Na-K-Cl cotransporters. J Bioenerg Biomembr 30:161\u2013172","journal-title":"J Bioenerg Biomembr"},{"key":"19_CR157","first-page":"773","volume":"25","author":"JA Kim","year":"2011","unstructured":"Kim JA, Yang H, Hwang I et al (2011) Expression patterns and potential action of the calcium transport genes trpv5, trpv6, ncx1 and pmca1b in the canine duodenum, kidney and uterus. In Vivo 25:773\u2013780","journal-title":"In Vivo"},{"issue":"11","key":"19_CR158","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1292\/jvms.11-0141","volume":"73","author":"I Hwang","year":"2011","unstructured":"Hwang I, Jung EM, Yang H et al (2011) Tissue-specific expression of the calcium transporter genes TRPV5, TRPV6, NCX1, and PMCA1b in the duodenum, kidney and heart of Equus caballus. J Vet Med Sci 73(11):1437\u20131444","journal-title":"J Vet Med Sci"},{"key":"19_CR159","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1006\/geno.2001.6606","volume":"76","author":"JB Peng","year":"2001","unstructured":"Peng JB, Brown EM, Hedigerb MA (2001) Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. Genomics 76:99\u2013109","journal-title":"Genomics"},{"key":"19_CR160","doi-asserted-by":"crossref","first-page":"28186","DOI":"10.1074\/jbc.M909686199","volume":"275","author":"JB Peng","year":"2000","unstructured":"Peng JB, Chen XZ, Berger UV et al (2000) A rat kidney-specific calcium transporter in the distal nephron. J Biol Chem 275:28186\u201328194","journal-title":"J Biol Chem"},{"key":"19_CR161","doi-asserted-by":"publisher","first-page":"8375","DOI":"10.1074\/jbc.274.13.8375","volume":"274","author":"JGJ Hoenderop","year":"1999","unstructured":"Hoenderop JGJ, Van der Kemp AW, Hartog A et al (1999) Molecular identification of the apical epithelial Ca2+ channel in 1, 25-vitamin D3 responsive epithelia. J Biol Chem 274:8375\u20138378","journal-title":"J Biol Chem"},{"key":"19_CR162","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1113\/jphysiol.2001.012917","volume":"537","author":"JG Hoenderop","year":"2001","unstructured":"Hoenderop JG, Vennekens R, M\u00fcller D et al (2001) Function and expression of the epithelial Ca(2+) channel family: comparison of mammalian ECaC1 and 2. J Physiol 537:747\u2013761","journal-title":"J Physiol"},{"key":"19_CR163","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/978-3-540-34891-7_12","volume":"179","author":"AR Mensenkamp","year":"2007","unstructured":"Mensenkamp AR, Hoenderop JG, Bindels RJ (2007) TRPV5, the gateway to Ca2+ homeostasis. Handb Exp Pharmacol 179:207\u2013220","journal-title":"Handb Exp Pharmacol"},{"key":"19_CR164","doi-asserted-by":"publisher","first-page":"F1241","DOI":"10.1152\/ajprenal.00376.2005","volume":"290","author":"M Goel","year":"2006","unstructured":"Goel M, Sinkins WG, Zuo CD et al (2006) Identification and localization of TRPC channels in the rat kidney. Am J Physiol Renal Physiol 290:F1241\u2013F1252","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR165","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.bbrc.2011.04.005","volume":"408","author":"DV Ilatovskaya","year":"2011","unstructured":"Ilatovskaya DV, Levchenko V, Ryan RP et al (2011) NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli. Biochem Biophys Res Commun 408:242\u2013247","journal-title":"Biochem Biophys Res Commun"},{"key":"19_CR166","doi-asserted-by":"publisher","first-page":"C357","DOI":"10.1152\/ajpcell.00068.2004","volume":"287","author":"X Wang","year":"2004","unstructured":"Wang X, Pluznick JL, Wei P et al (2004) TRPC4 forms store-operated Ca2+ channels in mouse mesangial cells. Am J Physiol Cell Physiol 287:C357\u2013C364","journal-title":"Am J Physiol Cell Physiol"},{"key":"19_CR167","doi-asserted-by":"publisher","first-page":"F1381","DOI":"10.1152\/ajprenal.00185.2007","volume":"293","author":"S Graham","year":"2007","unstructured":"Graham S, Ding M, Sours-Brothers S et al (2007) Downregulation of TRPC6 protein expression by high glucose, a possible mechanism for the impaired Ca2+ signaling in glomerular mesangial cells in diabetes. Am J Physiol Renal Physiol 293:F1381\u2013F1390","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR168","doi-asserted-by":"publisher","first-page":"F1507","DOI":"10.1152\/ajprenal.00268.2005","volume":"290","author":"S Sours","year":"2006","unstructured":"Sours S, Du J, Chu S et al (2006) Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. Am J Physiol Renal Physiol 290:F1507\u2013F1515","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR169","doi-asserted-by":"publisher","first-page":"673","DOI":"10.3181\/0809-RM-279","volume":"234","author":"S Sours-Brothers","year":"2009","unstructured":"Sours-Brothers S, Ding M, Graham S et al (2009) Interaction between TRPC1\/TRPC4 assembly and STIM1 contributes to store-operated Ca2+ entry in mesangial cells. Exp Biol Med (Maywood) 234:673\u2013682","journal-title":"Exp Biol Med (Maywood)"},{"key":"19_CR170","doi-asserted-by":"publisher","first-page":"34718","DOI":"10.1074\/jbc.M507793200","volume":"280","author":"MK Raychowdhury","year":"2005","unstructured":"Raychowdhury MK, McLaughlin M, Ramos AJ et al (2005) Characterization of single channel currents from primary cilia of renal epithelial cells. J Biol Chem 280:34718\u201334722","journal-title":"J Biol Chem"},{"key":"19_CR171","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1097\/01.ASN.0000029587.47950.25","volume":"13","author":"BK Yoder","year":"2002","unstructured":"Yoder BK, Hou X, Guay-Woodford LM (2002) The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 13:2508\u20132516","journal-title":"J Am Soc Nephrol"},{"key":"19_CR172","doi-asserted-by":"publisher","first-page":"2600","DOI":"10.1128\/MCB.23.7.2600-2607.2003","volume":"23","author":"Y Luo","year":"2003","unstructured":"Luo Y, Vassilev PM, Li X et al (2003) Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia. Mol Cell Biol 23:2600\u20132607","journal-title":"Mol Cell Biol"},{"key":"19_CR173","doi-asserted-by":"publisher","first-page":"F1476","DOI":"10.1152\/ajprenal.00186.2007","volume":"293","author":"M Goel","year":"2007","unstructured":"Goel M, Sinkins WG, Zuo CD et al (2007) Vasopressin-induced membrane trafficking of TRPC3 and AQP2 channels in cells of the rat renal collecting duct. Am J Physiol Renal Physiol 293:F1476\u2013F1488","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR174","doi-asserted-by":"publisher","first-page":"12908","DOI":"10.1074\/jbc.M410013200","volume":"280","author":"BC Bandyopadhyay","year":"2005","unstructured":"Bandyopadhyay BC, Swaim WD, Liu X et al (2005) Apical localization of a functional TRPC3\/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. J Biol Chem 280:12908\u201312916","journal-title":"J Biol Chem"},{"key":"19_CR175","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1111\/j.1748-1716.2010.02141.x","volume":"200","author":"M Salomonsson","year":"2010","unstructured":"Salomonsson M, Braunstein TH, Holstein-Rathlou NH et al (2010) Na+-independent, nifedipine-resistant rat afferent arteriolar Ca2+ responses to noradrenaline: possible role of TRPC channels. Acta Physiol (Oxf) 200:265\u2013278","journal-title":"Acta Physiol (Oxf)"},{"key":"19_CR176","doi-asserted-by":"publisher","first-page":"C942","DOI":"10.1152\/ajpcell.00417.2004","volume":"288","author":"W Lee-Kwon","year":"2005","unstructured":"Lee-Kwon W, Wade JB, Zhang Z et al (2005) Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta. Am J Physiol Cell Physiol 288:C942\u2013C949","journal-title":"Am J Physiol Cell Physiol"},{"key":"19_CR177","doi-asserted-by":"publisher","first-page":"2086","DOI":"10.1172\/JCI33004","volume":"117","author":"S Muallem","year":"2007","unstructured":"Muallem S, Moe OW (2007) When EGF is offside, magnesium is wasted. J Clin Invest 117:2086\u20132089","journal-title":"J Clin Invest"},{"key":"19_CR178","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1074\/jbc.M311201200","volume":"279","author":"T Voets","year":"2004","unstructured":"Voets T, Nilius B, Hoefs S et al (2004) TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem 279:19\u201325","journal-title":"J Biol Chem"},{"key":"19_CR179","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1111\/j.1474-8673.1989.tb00214.x","volume":"9","author":"CA Maggi","year":"1989","unstructured":"Maggi CA, Santicioli P, Manzini S et al (1989) Functional studies on the cholinergic and sympathetic innervation of the rat proximal urethra: effect of pelvic ganglionectomy or experimental diabetes. J Auton Pharmacol 9:231\u2013241","journal-title":"J Auton Pharmacol"},{"key":"19_CR180","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1111\/j.1748-1716.1990.tb09011.x","volume":"140","author":"PO Andersson","year":"1990","unstructured":"Andersson PO, Malmgren A, Uvelius B (1990) Functional responses of different muscle types of the female rat urethra in vitro. Acta Physiol Scand 140:365\u2013372","journal-title":"Acta Physiol Scand"},{"key":"19_CR181","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0014-2999(87)90736-9","volume":"143","author":"CA Maggi","year":"1987","unstructured":"Maggi CA, Giuliani S, Santicioli P et al (1987) Visceromotor responses to calcitonin gene-related peptide (CGRP) in the rat lower urinary tract: evidence for a transmitter role in the capsaicin-sensitive nerves of the ureter. Eur J Pharmacol 143:73\u201382","journal-title":"Eur J Pharmacol"},{"key":"19_CR182","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0014-2999(97)01223-5","volume":"335","author":"S Nishizawa","year":"1997","unstructured":"Nishizawa S, Igawa Y, Okada N et al (1997) Capsaicin-induced nitric-oxide-dependent relaxation in isolated dog urethra. Eur J Pharmacol 335:211\u2013219","journal-title":"Eur J Pharmacol"},{"key":"19_CR183","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/S0022-5347(17)35759-2","volume":"150","author":"B Conte","year":"1993","unstructured":"Conte B, Maggi CA, Giachetti A et al (1993) Intraurethral capsaicin produces reflex \u00adactivation of the striated urethral sphincter in urethane-anesthetized male rats. J Urol 150:1271\u20131277","journal-title":"J Urol"},{"key":"19_CR184","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1007\/BF00166980","volume":"335","author":"CA Maggi","year":"1987","unstructured":"Maggi CA, Santicioli P, Abelli L et al (1987) Regional differences in the effects of capsaicin and tachykinins on motor activity and vascular permeability of the rat lower urinary tract. Naunyn Schmiedebergs Arch Pharmacol 335:636\u2013645","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"19_CR185","doi-asserted-by":"publisher","first-page":"E559","DOI":"10.1152\/ajpendo.90289.2008","volume":"295","author":"HY Peng","year":"2008","unstructured":"Peng HY, Huang PC, Liao JM et al (2008) Estrous cycle variation of TRPV1-mediated cross-organ sensitization between uterus and NMDA-dependent pelvic-urethra reflex activity. Am J Physiol Endocrinol Metab 295:E559\u2013E568","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"19_CR186","doi-asserted-by":"publisher","first-page":"F1324","DOI":"10.1152\/ajprenal.00126.2008","volume":"295","author":"HY Peng","year":"2008","unstructured":"Peng HY, Chang HM, Lee SD et al (2008) TRPV1 mediates the uterine capsaicin-induced NMDA NR2B-dependent cross-organ reflex sensitization in anesthetized rats. Am J Physiol Renal Physiol 295:F1324\u2013F1335","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR187","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1016\/j.eururo.2008.04.042","volume":"55","author":"C Gratzke","year":"2009","unstructured":"Gratzke C, Streng T, Waldkirch E et al (2009) Transient receptor potential A1 (TRPA1) activity in the human urethra \u2013 evidence for a functional role for TRPA1 in the outflow region. Eur Urol 55:696\u2013704","journal-title":"Eur Urol"},{"key":"19_CR188","doi-asserted-by":"publisher","first-page":"2070","DOI":"10.1016\/j.juro.2009.12.093","volume":"183","author":"P Weinhold","year":"2010","unstructured":"Weinhold P, Gratzke C, Streng T et al (2010) TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation. J Urol 183:2070\u20132076","journal-title":"J Urol"},{"key":"19_CR189","first-page":"519","volume":"29","author":"ZP Xu","year":"2009","unstructured":"Xu ZP, Gao WC, Wang HP et al (2009) Expression of transient receptor potential subfamily mRNAs in rat testes. Nan Fang Yi Ke Da Xue Xue Bao 29:519\u2013520","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"key":"19_CR190","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1016\/j.fertnstert.2007.10.081","volume":"90","author":"SC Mizrak","year":"2008","unstructured":"Mizrak SC, van Dissel-Emiliani FM (2008) Transient receptor potential vanilloid receptor-1 confers heat resistance to male germ cells. Fertil Steril 90:1290\u20131293","journal-title":"Fertil Steril"},{"key":"19_CR191","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1007\/s11033-009-9503-9","volume":"37","author":"S Li","year":"2010","unstructured":"Li S, Wang X, Ye H et al (2010) Distribution profiles of transient receptor potential melastatin- and vanilloid-related channels in rat spermatogenic cells and sperm. Mol Biol Rep 37:1287\u20131293","journal-title":"Mol Biol Rep"},{"key":"19_CR192","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1002\/jcp.22493","volume":"226","author":"P Mart\u00ednez-L\u00f3pez","year":"2011","unstructured":"Mart\u00ednez-L\u00f3pez P, Trevi\u00f1o CL, de la Vega-Beltr\u00e1n JL et al (2011) TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction. J Cell Physiol 226:1620\u20131631","journal-title":"J Cell Physiol"},{"key":"19_CR193","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.bcp.2007.09.004","volume":"75","author":"C Auzanneau","year":"2008","unstructured":"Auzanneau C, Norez C, Antigny F et al (2008) Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel. Biochem Pharmacol 75:476\u2013483","journal-title":"Biochem Pharmacol"},{"key":"19_CR194","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/1477-7827-6-52","volume":"6","author":"SC Mizrak","year":"2008","unstructured":"Mizrak SC, Gadella BM, Erdost H et al (2008) Spermatogonial stem cell sensitivity to capsaicin: an in vitro study. Reprod Biol Endocrinol 6:52","journal-title":"Reprod Biol Endocrinol"},{"key":"19_CR195","first-page":"17","volume":"55","author":"OI Boldyrev","year":"2009","unstructured":"Boldyrev OI, Sotkis HV, IeM K et al (2009) Expression of the cold receptor TRPM8 in the smooth muscles of the seminal ejaculatory ducts in rats. Fiziol Zh 55:17\u201327","journal-title":"Fiziol Zh"},{"key":"19_CR196","first-page":"30","volume":"55","author":"IB Filippov","year":"2009","unstructured":"Filippov IB, Vladymyrova IA, IeM K (2009) Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol. Fiziol Zh 55:30\u201340","journal-title":"Fiziol Zh"},{"key":"19_CR197","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/j.1474-8673.1987.tb00153.x","volume":"7","author":"CA Maggi","year":"1987","unstructured":"Maggi CA, Giuliani S, Santicioli P et al (1987) Capsaicin-induced inhibition of motility of the rat isolated vas deferens: do multiple neuropeptides mediate the visceromotor effects of capsaicin? J Auton Pharmacol 7:243\u2013255","journal-title":"J Auton Pharmacol"},{"key":"19_CR198","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1111\/j.1476-5381.1989.tb12646.x","volume":"98","author":"JL Ellis","year":"1989","unstructured":"Ellis JL, Burnstock G (1989) Modulation of neurotransmission in the guinea-pig vas deferens by capsaicin: involvement of calcitonin gene-related peptide and substance P. Br J Pharmacol 98:707\u2013713","journal-title":"Br J Pharmacol"},{"key":"19_CR199","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1111\/j.2042-7158.1996.tb05918.x","volume":"48","author":"KA Wardle","year":"1996","unstructured":"Wardle KA, Furey G, Sanger GJ (1996) Pharmacological characterization of the vanilloid receptor in the rat isolated vas deferens. J Pharm Pharmacol 48:285\u2013291","journal-title":"J Pharm Pharmacol"},{"key":"19_CR200","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/S0014-2999(98)00841-3","volume":"364","author":"A Filippelli","year":"1999","unstructured":"Filippelli A, Falciani M, Piucci B (1999) Endothelin-1 affects capsaicin-evoked release of neuropeptides from rat vas deferens. Eur J Pharmacol 364:183\u2013191","journal-title":"Eur J Pharmacol"},{"key":"19_CR201","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1038\/sj.bjp.0703850","volume":"132","author":"RA Ross","year":"2001","unstructured":"Ross RA, Gibson TM, Brockie HC et al (2001) Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. Br J Pharmacol 132:631\u2013640","journal-title":"Br J Pharmacol"},{"key":"19_CR202","first-page":"191","volume":"123","author":"A Thomas","year":"2006","unstructured":"Thomas A, Pertwee RG (2006) The bioassay of cannabinoids using the mouse isolated vas deferens. Methods Mol Med 123:191\u2013207","journal-title":"Methods Mol Med"},{"key":"19_CR203","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.ejphar.2011.06.031","volume":"667","author":"M Sheykhzade","year":"2011","unstructured":"Sheykhzade M, Gupta S, S\u00f8rensen T et al (2011) Characterization of capsaicin induced responses in mice vas deferens: evidence of CGRP uptake. Eur J Pharmacol 667:375\u2013382","journal-title":"Eur J Pharmacol"},{"key":"19_CR204","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1111\/j.1745-7262.2007.00291.x","volume":"9","author":"HP Wang","year":"2007","unstructured":"Wang HP, Pu XY, Wang XH (2007) Distribution profiles of transient receptor potential melastatin-related and vanilloid-related channels in prostatic tissue in rat. Asian J Androl 9:634\u2013640","journal-title":"Asian J Androl"},{"key":"19_CR205","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.eururo.2005.01.009","volume":"48","author":"P Dinis","year":"2005","unstructured":"Dinis P, Charrua A, Avelino A et al (2005) The distribution of sensory fibres immunoreactive for the TRPV1 (capsaicin) receptor in the human prostate. Eur Urol 48:162\u2013167","journal-title":"Eur Urol"},{"key":"19_CR206","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1002\/pros.10264","volume":"56","author":"F Van der Aa","year":"2003","unstructured":"Van der Aa F, Roskams T, Blyweert W et al (2003) Interstitial cells in the human prostate: a new therapeutic target? Prostate 56:250\u2013255","journal-title":"Prostate"},{"key":"19_CR207","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1016\/j.eururo.2009.08.019","volume":"57","author":"C Gratzke","year":"2009","unstructured":"Gratzke C, Weinhold P, Reich O et al (2009) Transient receptor potential A1 and cannabinoid receptor activity in human normal and hyperplastic prostate: relation to nerves and interstitial cells. Eur Urol 57:902\u2013910","journal-title":"Eur Urol"},{"key":"19_CR208","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1677\/erc.1.00969","volume":"12","author":"G Bidaux","year":"2005","unstructured":"Bidaux G, Roudbaraki M, Merle C et al (2005) Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: functional androgen receptor requirement. Endocr Relat Cancer 12:367\u2013382","journal-title":"Endocr Relat Cancer"},{"key":"19_CR209","first-page":"3","volume":"53","author":"AP Kondrats\u2019ky\u012d","year":"2007","unstructured":"Kondrats\u2019ky\u012d AP, Sotkis HV, Boldyriev OI (2007) Functional identification of the TRPM8 cold receptor in rat prostate epithelial cells. Fiziol Zh 53:3\u201313","journal-title":"Fiziol Zh"},{"key":"19_CR210","first-page":"3760","volume":"61","author":"L Tsavaler","year":"2001","unstructured":"Tsavaler L, Shapero MH, Morkowski S et al (2001) Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res 61:3760\u20133769","journal-title":"Cancer Res"},{"key":"19_CR211","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1172\/JCI30168","volume":"117","author":"G Bidaux","year":"2007","unstructured":"Bidaux G, Flourakis M, Thebault S et al (2007) Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function. J Clin Invest 117:1647\u20131657","journal-title":"J Clin Invest"},{"key":"19_CR212","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3109\/00365599409180522","volume":"28","author":"M Lazzeri","year":"1994","unstructured":"Lazzeri M, Barbanti G, Beneforti P et al (1994) Intraurethrally infused capsaicin induces penile erection in humans. Scand J Urol Nephrol 28:409\u2013412","journal-title":"Scand J Urol Nephrol"},{"key":"19_CR213","first-page":"443","volume":"36","author":"VU Bai","year":"2010","unstructured":"Bai VU, Murthy S, Chinnakannu K et al (2010) Androgen regulated TRPM8 expression: a potential mRNA marker for metastatic prostate cancer detection in body fluids. Int J Oncol 36:443\u2013450","journal-title":"Int J Oncol"},{"key":"19_CR214","doi-asserted-by":"publisher","first-page":"40174","DOI":"10.1074\/jbc.M605779200","volume":"281","author":"AF Vanden","year":"2006","unstructured":"Vanden AF, Zholos A, Bidaux G et al (2006) Ca2+-independent phospholipase A2-dependent gating of TRPM8 by lysophospholipids. J Biol Chem 281:40174\u201340182","journal-title":"J Biol Chem"},{"key":"19_CR215","doi-asserted-by":"publisher","first-page":"8365","DOI":"10.1158\/0008-5472.CAN-04-2146","volume":"64","author":"L Zhang","year":"2004","unstructured":"Zhang L, Barritt GJ (2004) Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells. Cancer Res 64:8365\u20138373","journal-title":"Cancer Res"},{"key":"19_CR216","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bbadis.2008.09.012","volume":"1792","author":"SH Kim","year":"2008","unstructured":"Kim SH, Nam JH, Park EJ et al (2008) Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells. Biochim Biophys Acta 1792:33\u201338","journal-title":"Biochim Biophys Acta"},{"key":"19_CR217","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.bbrc.2011.01.094","volume":"406","author":"SH Kim","year":"2011","unstructured":"Kim SH, Kim SY, Park EJ et al (2011) Icilin induces G1 arrest through activating JNK and p38 kinase in a TRPM8-independent manner. Biochem Biophys Res Commun 406:30\u201335","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"19_CR218","doi-asserted-by":"publisher","first-page":"4797","DOI":"10.1007\/s11033-011-1271-7","volume":"39","author":"Z Yang","year":"2012","unstructured":"Yang Z, Wang X, Zhu G et al (2012) Effect of surgical castration on expression of TRPM8 in urogenital tract of male rats. Mol Biol Rep 39(4):4797\u20134802","journal-title":"Mol Biol Rep"},{"key":"19_CR219","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1002\/mrd.20312","volume":"71","author":"SC Teilmann","year":"2005","unstructured":"Teilmann SC, Byskov AG, Pedersen PA et al (2005) Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs. Mol Reprod Dev 71:444\u2013452","journal-title":"Mol Reprod Dev"},{"key":"19_CR220","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1083\/jcb.200409070","volume":"168","author":"YN Andrade","year":"2005","unstructured":"Andrade YN, Fernandes J, V\u00e1zquez E et al (2005) TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity. J Cell Biol 168:869\u2013874","journal-title":"J Cell Biol"},{"key":"19_CR221","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1007\/978-94-007-0265-3_47","volume":"704","author":"J D\u00f6rr","year":"2011","unstructured":"D\u00f6rr J, Fecher-Trost C (2011) TRP channels in female reproductive organs and placenta. Adv Exp Med Biol 704:909\u2013928","journal-title":"Adv Exp Med Biol"},{"issue":"3","key":"19_CR222","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1523\/JNEUROSCI.4772-07.2008","volume":"28","author":"V Meseguer","year":"2008","unstructured":"Meseguer V, Karashima Y, Talavera K et al (2008) Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole. J Neurosci 28(3):576\u2013586","journal-title":"J Neurosci"},{"key":"19_CR223","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1111\/j.1365-2559.2010.03683.x","volume":"57","author":"C Kalogris","year":"2010","unstructured":"Kalogris C, Caprodossi S, Amantini C et al (2010) Expression of transient receptor potential vanilloid-1 (TRPV1) in urothelial cancers of human bladder: relation to clinicopathological and molecular parameters. Histopathology 57:744\u2013752","journal-title":"Histopathology"},{"key":"19_CR224","doi-asserted-by":"publisher","first-page":"509.e1","DOI":"10.1016\/j.urology.2010.03.029","volume":"76","author":"T Yamada","year":"2010","unstructured":"Yamada T, Ueda T, Shibata Y et al (2010) TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer. Urology 76:509.e1\u2013509.e7","journal-title":"Urology"},{"key":"19_CR225","first-page":"13","volume":"80","author":"F Ziglioli","year":"2009","unstructured":"Ziglioli F, Frattini A, Maestroni U et al (2009) Vanilloid-mediated apoptosis in prostate cancer cells through a TRPV-1 dependent and a TRPV-1-independent mechanism. Acta Biomed 80:13\u201320","journal-title":"Acta Biomed"},{"key":"19_CR226","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s10495-005-3275-z","volume":"11","author":"AM S\u00e1nchez","year":"2006","unstructured":"S\u00e1nchez AM, S\u00e1nchez MG, Malagarie-Cazenave S et al (2006) Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin. Apoptosis 11:89\u201399","journal-title":"Apoptosis"},{"key":"19_CR227","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.cyto.2011.03.010","volume":"54","author":"S Malagarie-Cazenave","year":"2011","unstructured":"Malagarie-Cazenave S, Olea-Herrero N, Vara D et al (2011) The vanilloid capsaicin induces IL-6 secretion in prostate PC-3 cancer cells. Cytokine 54:330\u2013337","journal-title":"Cytokine"},{"key":"19_CR228","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1007\/s10495-007-0119-z","volume":"12","author":"AM S\u00e1nchez","year":"2007","unstructured":"S\u00e1nchez AM, Malagarie-Cazenave S, Olea N et al (2007) Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide \u00adaccumulation, neutral sphingomyelinase, and JNK activation. Apoptosis 12:2013\u20132024","journal-title":"Apoptosis"},{"key":"19_CR229","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.1158\/0008-5472.CAN-05-0087","volume":"66","author":"A Mori","year":"2006","unstructured":"Mori A, Lehmann S, O\u2019Kelly J et al (2006) Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells. Cancer Res 66:3222\u20133229","journal-title":"Cancer Res"},{"key":"19_CR230","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/j.bbrc.2008.05.138","volume":"372","author":"AM S\u00e1nchez","year":"2008","unstructured":"S\u00e1nchez AM, Mart\u00ednez-Botas J, Malagarie-Cazenave S et al (2008) Induction of the endoplasmic reticulum stress protein GADD153\/CHOP by capsaicin in prostate PC-3 cells: a microarray study. Biochem Biophys Res Commun 372:785\u2013791","journal-title":"Biochem Biophys Res Commun"},{"key":"19_CR231","doi-asserted-by":"crossref","first-page":"E9","DOI":"10.5489\/cuaj.784","volume":"4","author":"B Jankovic","year":"2010","unstructured":"Jankovic B, Loblaw DA, Nam R (2010) Capsaicin may slow PSA doubling time: case report and literature review. Can Urol Assoc J 4:E9\u2013E11","journal-title":"Can Urol Assoc J"},{"key":"19_CR232","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.tiv.2005.09.014","volume":"20","author":"JK Huang","year":"2005","unstructured":"Huang JK, Cheng HH, Huang CJ et al (2005) Effect of capsazepine on cytosolic Ca(2+) levels and proliferation of human prostate cancer cells. Toxicol In Vitro 20:567\u2013574","journal-title":"Toxicol In Vitro"},{"key":"19_CR233","doi-asserted-by":"publisher","first-page":"4611","DOI":"10.1038\/onc.2010.210","volume":"29","author":"D Gkika","year":"2010","unstructured":"Gkika D, Flourakis M, Lemonnier L et al (2010) PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression. Oncogene 29:4611\u20134616","journal-title":"Oncogene"},{"issue":"5","key":"19_CR234","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1038\/aja.2011.18","volume":"13","author":"D Gkika","year":"2011","unstructured":"Gkika D, Prevarskaya N (2011) TRP channels in prostate cancer: the good, the bad and the ugly? Asian J Androl 13(5):673\u2013676","journal-title":"Asian J Androl"},{"key":"19_CR235","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/aja.2009.1","volume":"11","author":"ZH Yang","year":"2009","unstructured":"Yang ZH, Wang XH, Wang HP et al (2009) Effects of TRPM8 on the proliferation and motility of prostate cancer PC-3 cells. Asian J Androl 11:157\u2013165","journal-title":"Asian J Androl"}],"container-title":["Methods in Pharmacology and Toxicology","TRP Channels in Drug Discovery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-62703-077-9_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T15:30:22Z","timestamp":1714404622000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-62703-077-9_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"ISBN":["9781627030762","9781627030779"],"references-count":235,"URL":"https:\/\/doi.org\/10.1007\/978-1-62703-077-9_19","relation":{},"ISSN":["1557-2153","1940-6053"],"issn-type":[{"type":"print","value":"1557-2153"},{"type":"electronic","value":"1940-6053"}],"subject":[],"published":{"date-parts":[[2012]]},"assertion":[{"value":"2 August 2012","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}