{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T17:12:19Z","timestamp":1725556339541},"publisher-location":"Berlin, Heidelberg","reference-count":25,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783642132131"},{"type":"electronic","value":"9783642132148"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010]]},"DOI":"10.1007\/978-3-642-13214-8_25","type":"book-chapter","created":{"date-parts":[[2010,5,18]],"date-time":"2010-05-18T23:48:39Z","timestamp":1274226519000},"page":"193-200","source":"Crossref","is-referenced-by-count":1,"title":["Applying a Metabolic Footprinting Approach to Characterize the Impact of the Recombinant Protein Production in Escherichia coli"],"prefix":"10.1007","author":[{"given":"S\u00f3nia","family":"Carneiro","sequence":"first","affiliation":[]},{"given":"Silas G.","family":"Villas-B\u00f4as","sequence":"additional","affiliation":[]},{"given":"Isabel","family":"Rocha","sequence":"additional","affiliation":[]},{"given":"Eug\u00e9nio C.","family":"Ferreira","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"25_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1002\/bit.1054","volume":"73","author":"M. Akesson","year":"2001","unstructured":"Akesson, M., Hagander, P., Axelsson, J.P.: Avoiding acetate accumulation in Escherichia coli cultures using feedback control of glucose feeding. Biotechnol. Bioeng.\u00a073, 223\u2013230 (2001)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR2","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1002\/bit.260350704","volume":"35","author":"W.E. Bentley","year":"1990","unstructured":"Bentley, W.E., Mirjalili, N., Andersen, D.C., et al.: Plasmid-encoded protein - the principal factor in the metabolic burden associated with recombinant bacteria. Biotechnol. Bioeng.\u00a035, 668\u2013681 (1990)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR3","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/bit.20436","volume":"90","author":"J. Bonomo","year":"2005","unstructured":"Bonomo, J., Gill, R.T.: Amino acid content of recombinant proteins influences the metabolic burden response. Biotechnol. Bioeng.\u00a090, 116\u2013126 (2005)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR4","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1002\/bit.10845","volume":"84","author":"T. Bulter","year":"2003","unstructured":"Bulter, T., Bernstein, J.R., Liao, J.C.: A perspective of metabolic engineering strategies: Moving up the systems hierarchy. Biotechnol. Bioeng.\u00a084, 815\u2013821 (2003)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR5","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s00253-007-1039-0","volume":"76","author":"C.P. Chou","year":"2007","unstructured":"Chou, C.P.: Engineering cell physiology to enhance recombinant protein production in Escherichia coli. Appl. Microbiol. Biotechnol.\u00a076, 521\u2013532 (2007)","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"25_CR6","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1021\/bp050073s","volume":"21","author":"C.R. Dittrich","year":"2005","unstructured":"Dittrich, C.R., Bennett, G.N., San, K.Y.: Characterization of the acetate-producing pathways in Escherichia coli. Biotechnol. Progr.\u00a021, 1062\u20131067 (2005)","journal-title":"Biotechnol. Progr."},{"key":"25_CR7","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.tibtech.2006.09.001","volume":"24","author":"M.A. Eiteman","year":"2006","unstructured":"Eiteman, M.A., Altman, E.: Overcoming acetate in Escherichia coli recombinant protein fermentations. Trends Biotechnol.\u00a024, 530\u2013536 (2006)","journal-title":"Trends Biotechnol."},{"key":"25_CR8","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1006\/jtbi.2002.3101","volume":"219","author":"V.V. Ganusov","year":"2002","unstructured":"Ganusov, V.V., Brilkov, A.V.: Estimating the instability parameters of plasmid-bearing cells. I. Chemostat culture. J Theor. Biol.\u00a0219, 193\u2013205 (2002)","journal-title":"J Theor. Biol."},{"key":"25_CR9","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0734-9750(95)00004-A","volume":"13","author":"B.R. Glick","year":"1995","unstructured":"Glick, B.R.: Metabolic load and heterologous gene-expression. Biotechnol. Adv.\u00a013, 247\u2013261 (1995)","journal-title":"Biotechnol. Adv."},{"key":"25_CR10","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s00253-004-1814-0","volume":"67","author":"S. Jana","year":"2005","unstructured":"Jana, S., Deb, J.K.: Strategies for efficient production of heterologous proteins in Escherichia coli. Appl. Microbiol. Biotechnol.\u00a067, 289\u2013298 (2005)","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"25_CR11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00449-002-0305-x","volume":"25","author":"D. Levisauskas","year":"2003","unstructured":"Levisauskas, D., Galvanauskas, V., Henrich, S., et al.: Model-based optimization of viral capsid protein production in fed-batch culture of recombinant Escherichia coli. Bioprocess Biosyst. Eng.\u00a025, 255\u2013262 (2003)","journal-title":"Bioprocess Biosyst. Eng."},{"key":"25_CR12","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1021\/bp025546z","volume":"19","author":"R. Mahadevan","year":"2003","unstructured":"Mahadevan, R., Doyle, F.J.: On-line optimization of recombinant product in a fed-batch bioreactor. Biotechnol. Progr.\u00a019, 639\u2013646 (2003)","journal-title":"Biotechnol. Progr."},{"key":"25_CR13","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.tibtech.2008.05.008","volume":"26","author":"V. Mapelli","year":"2008","unstructured":"Mapelli, V., Olsson, L., Nielsen, J.: Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology. Trends Biotechnol.\u00a026, 490\u2013497 (2008)","journal-title":"Trends Biotechnol."},{"key":"25_CR14","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1002\/bit.10630","volume":"82","author":"H.G. Menzella","year":"2003","unstructured":"Menzella, H.G., Ceccarelli, E.A., Gramajo, H.C.: Novel Escherichia coli strain allows efficient recombinant protein production using lactose as inducer. Biotechnol. Bioeng.\u00a082, 809\u2013817 (2003)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR15","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.bej.2004.09.012","volume":"22","author":"P. Ozkan","year":"2005","unstructured":"Ozkan, P., Sariyar, B., Utkur, F.O., et al.: Metabolic flux analysis of recombinant protein overproduction in Escherichia coli. Biochem. Eng. J.\u00a022, 167\u2013195 (2005)","journal-title":"Biochem. Eng. J."},{"key":"25_CR16","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/S0003-2670(02)00347-1","volume":"462","author":"I. Rocha","year":"2002","unstructured":"Rocha, I., Ferreira, E.C.: On-line simultaneous monitoring of glucose and acetate with FIA during high cell density fermentation of recombinant E. coli. Anal. Chim. Acta.\u00a0462, 293\u2013304 (2002)","journal-title":"Anal. Chim. Acta."},{"key":"25_CR17","doi-asserted-by":"crossref","unstructured":"Rocha, I., Veloso, A.C.A., Carneiro, S., et al.: Implementation of a specific rate controller in a fed-batch E. coli fermentation. In: Proceedings of the 17th World Congress The International Federation of Automatic Control (2008)","DOI":"10.3182\/20080706-5-KR-1001.02632"},{"key":"25_CR18","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1002\/bit.20327","volume":"88","author":"A. Rozkov","year":"2004","unstructured":"Rozkov, A., vignone-Rossa, C.A., Ertl, P.F., et al.: Characterization of the metabolic burden on Escherichia coli DH1 cells imposed by the presence of a plasmid containing a gene therapy sequence. Biotechnol. Bioeng.\u00a088, 909\u2013915 (2004)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR19","doi-asserted-by":"crossref","first-page":"374","DOI":"10.2144\/03342mt01","volume":"34","author":"A.I. Saeed","year":"2003","unstructured":"Saeed, A.I., Sharov, V., White, J., et al.: TM4: a free, open-source system for microarray data management and analysis. Biotechniques\u00a034, 374\u2013378 (2003)","journal-title":"Biotechniques"},{"key":"25_CR20","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/S0922-338X(97)87330-8","volume":"83","author":"V.M. Saucedo","year":"1997","unstructured":"Saucedo, V.M., Karim, M.N.: Analysis and comparison of input-output models in a recombinant fed-batch fermentation. J. Ferment. Bioeng.\u00a083, 70\u201378 (1997)","journal-title":"J. Ferment. Bioeng."},{"key":"25_CR21","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1002\/(SICI)1097-0290(19960220)49:4<421::AID-BIT9>3.0.CO;2-R","volume":"49","author":"J. Shiloach","year":"1996","unstructured":"Shiloach, J., Kaufman, J., Guillard, A.S., et al.: Effect of glucose supply strategy on acetate accumulation, growth, and recombinant protein production by Escherichia coli BL21 ((\u03bbDE3) and Escherichia coli JM109. Biotechnol. Bioeng.\u00a049, 421\u2013428 (1996)","journal-title":"Biotechnol. Bioeng."},{"key":"25_CR22","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/0385-6380(88)90046-5","volume":"66","author":"N. Shimizu","year":"1988","unstructured":"Shimizu, N., Fukuzono, S., Fujimori, K., et al.: Fed-batch cultures of recombinant Escherichia coli with inhibitory substance concentration monitoring. J. Ferment. Technol.\u00a066, 187\u2013191 (1988)","journal-title":"J. Ferment. Technol."},{"key":"25_CR23","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1016\/S1044-0305(99)00047-1","volume":"10","author":"S.E. Stein","year":"1999","unstructured":"Stein, S.E.: An integrated method for spectrum extraction and compound identification from gas chromatography\/mass spectrometry data. J. Am. Soc. Mass Spectrom.\u00a010, 770\u2013781 (1999)","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"25_CR24","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/S0032-9592(00)00140-0","volume":"35","author":"D.C. Suarez","year":"2000","unstructured":"Suarez, D.C., Kilikian, B.V.: Acetic acid accumulation in aerobic growth of recombinant Escherichia coli. Process Biochem.\u00a035, 1051\u20131055 (2000)","journal-title":"Process Biochem."},{"key":"25_CR25","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.ab.2003.07.018","volume":"322","author":"S.G. Villas-Boas","year":"2003","unstructured":"Villas-Boas, S.G., Delicado, D.G., Akesson, M., et al.: Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry. Anal. Biochem.\u00a0322, 134\u2013138 (2003)","journal-title":"Anal. Biochem."}],"container-title":["Advances in Intelligent and Soft Computing","Advances in Bioinformatics"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-642-13214-8_25.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T07:58:12Z","timestamp":1619769492000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-642-13214-8_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"ISBN":["9783642132131","9783642132148"],"references-count":25,"URL":"https:\/\/doi.org\/10.1007\/978-3-642-13214-8_25","relation":{},"ISSN":["1867-5662","1867-5670"],"issn-type":[{"type":"print","value":"1867-5662"},{"type":"electronic","value":"1867-5670"}],"subject":[],"published":{"date-parts":[[2010]]}}}