{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:44:09Z","timestamp":1756993449200},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1979,1,1]],"date-time":"1979-01-01T00:00:00Z","timestamp":283996800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molec. Gen. Genet."],"published-print":{"date-parts":[[1979,1]]},"DOI":"10.1007\/bf00382276","type":"journal-article","created":{"date-parts":[[2004,11,7]],"date-time":"2004-11-07T16:49:28Z","timestamp":1099846168000},"page":"299-314","source":"Crossref","is-referenced-by-count":30,"title":["Mutations affecting the formation of acetohydroxy acid synthase II in Escherichia coli K-12"],"prefix":"10.1007","volume":"169","author":[{"given":"John M.","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank J.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. E.","family":"Umbarger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF00382276_CR1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1128\/JB.112.1.40-47.1972","volume":"112","author":"A. Avitabile","year":"1972","unstructured":"Avitabile, A., Carlomagno-Cerillo, M.S., Favre, R., Blasi, F.: Isolation of transducing phages for the histidine and isoleucinevaline operons in Escherichia coli K-12. J. Bacteriol. 112, 40\u201347 (1972)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF00382275","volume":"169","author":"M. Baez","year":"1979","unstructured":"Baez, M., Patin, D.W., Calhoun, D.H.: Deletion mapping of the ilvGOEDAC genes of Escherichia coli K-12. Mol. Gen. Genet. 169, 289\u2013297 (1979)","journal-title":"Mol. Gen. Genet."},{"key":"BF00382276_CR3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1128\/JB.62.3.293-300.1951","volume":"62","author":"G. Bertani","year":"1951","unstructured":"Bertani, G.: Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli. J. Bacteriol. 62, 293\u2013300 (1951)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1093\/genetics\/83.2.201","volume":"83","author":"B.M. Cohen","year":"1976","unstructured":"Cohen, B.M., Jones, E.: New map location of ilvO in Escherichia coli. Genetics 83, 201\u2013225 (1976)","journal-title":"Genetics"},{"key":"BF00382276_CR5","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1128\/JB.90.5.1238-1250.1965","volume":"90","author":"R. Curtiss","year":"1965","unstructured":"Curtiss, R., Charamella, L.J., Berg, C.M., Harris, P.E.: Kinetic and genetic analysis of D-cycloserine inhibition and resistance in Escherichia coli. J. Bacteriol. 90, 1238\u20131250 (1965)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR6","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1128\/JB.60.1.17-28.1950","volume":"60","author":"B.D. Davis","year":"1950","unstructured":"Davis, B.D., Mingioli, E.S.: Mutants of Escherichia coli requiring methionine or vitamin B12. J. Bacteriol. 60, 17\u201328 (1950)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0003-2697(73)90453-3","volume":"51","author":"D.E. Duggan","year":"1973","unstructured":"Duggan, D.E., Wechsler, J.A.: An assay for transaminase B enzyme activity in Escherichia coli K-12. Analyt. Biochem. 51, 67\u201379 (1973)","journal-title":"Analyt. Biochem."},{"key":"BF00382276_CR8","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/BF00269400","volume":"143","author":"R. Favre","year":"1976","unstructured":"Favre, R., Wiater, A., Puppo, S., Iaccarino, M., Noelle, R., Freundlich, M.: Expression of a valine resistant acetolactate synthase activity mediated by the ilvO and ilvG genes of Escherichia coli K-12. Mol. Gen. Genet. 143, 243\u2013252 (1976)","journal-title":"Mol. Gen. Genet."},{"key":"BF00382276_CR9","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0021-9258(18)72397-1","volume":"147","author":"T.E. Friedemann","year":"1943","unstructured":"Friedemann T.E., Haugen, G.E.: Pyruvic acid. II. The determination of keto acids in blood and urine. J. Biol. Chem. 147, 415\u2013442 (1943)","journal-title":"J. Biol. Chem."},{"key":"BF00382276_CR10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF00272247","volume":"156","author":"J. Guardiola","year":"1977","unstructured":"Guardiola, J., DeFelice, M., Lamberti, A., Iaccarino, M.: The acetolactate synthase isozymes of Escherichia coli K-12. Mol. Gen. Genet. 156, 17\u201325 (1977)","journal-title":"Mol. Gen. Genet."},{"key":"BF00382276_CR11","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1126\/science.1103291","volume":"190","author":"M.M. Howe","year":"1975","unstructured":"Howe, M.M., Bade, E.G.: Molecular biology of bacteriophage Mu. Science 190, 624\u2013632 (1975)","journal-title":"Science"},{"key":"BF00382276_CR12","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/0006-291X(74)90816-X","volume":"57","author":"E.L. Kline","year":"1974","unstructured":"Kline, E.L., Brown, C.S., Coleman, W.G., Jr., Umbarger, H.E.: Regulation of isoleucine-valine biosynthesis in an ilvDAC deletion strain of Escherichia coli K-12. Biochem. Biophys. Res. Commun. 57, 1144\u20131151 (1974)","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF00382276_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/JB.120.1.1-5.1974","volume":"120","author":"J. Louarn","year":"1974","unstructured":"Louarn, J., Funderburgh, M., Bird, R.E.: More precise mapping of the replication origin in Escherichia coli K-12. J. Bacteriol. 120, 1\u20135 (1974)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O.H. Lowry","year":"1951","unstructured":"Lowry, O.H., Rosebrough, N.J., Farr, A.L.: Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265\u2013275 (1951)","journal-title":"J. Biol. Chem."},{"key":"BF00382276_CR15","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1128\/JB.109.2.730-740.1972","volume":"109","author":"N.J. Marsh","year":"1972","unstructured":"Marsh, N.J., Duggan, D.E.: Ordering of mutant sites in the isoleucine-valine genes of Escherichia coli by use of merogenotes derived from F14: a new procedure for fine-structure mapping. J. Bacteriol. 109, 730\u2013740 (1972)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR16","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1128\/JB.120.2.715-723.1974","volume":"120","author":"D. McGilvray","year":"1974","unstructured":"McGilvray, D., Umbarger, H.E.: Regulation of transaminase C synthesis in Escherichia coli: conditional leucine auxotrophy. J. Bacteriol. 120, 715\u2013723 (1974)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR17","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1128\/JB.114.1.183-194.1973","volume":"114","author":"W.J. Pledger","year":"1973","unstructured":"Pledger, W.J., Umbarger, H.E.: Isoleucine and valine metabolism in Escherichia coli. XXI. Mutations affecting depression and valine resistance. J. Bacteriol. 114, 183\u2013194 (1973a)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR18","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1128\/JB.114.1.195-207.1973","volume":"114","author":"W.J. Pledger","year":"1973","unstructured":"Pledger, W.J., Umbarger, H.E.: Isoleucine and valine metabolism in Escherichia coli. XII. A pleiotropic mutation affecting induction of isomeroreductase activity. J. Bacteriol. 114, 195\u2013207 (1973b)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR19","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1128\/JB.89.3.654-660.1965","volume":"89","author":"T. Ramakrishnan","year":"1965","unstructured":"Ramakrishnan, T., Adelberg, E.A.: Regulatory mechanisms in the biosynthesis of isoleucine and valine. II. Identification of two operator genes. J. Bacteriol. 89, 654\u2013660 (1965)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR20","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/0042-6822(72)90152-3","volume":"49","author":"J.L. Rosner","year":"1972","unstructured":"Rosner, J.L.: Formation, induction, and curing of bacteriophage P1 lysogens. Virology 49, 679\u2013689 (1972)","journal-title":"Virology"},{"key":"BF00382276_CR21","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/BF00268374","volume":"148","author":"J.M. Smith","year":"1976","unstructured":"Smith, J.M., Smolin, D.E., Umbarger, H.E.: Polarity and the regulation of the ilv gene cluster in Escherichia coli strain K-12. Mol. Gen. Genet. 148, 111\u2013124 (1976)","journal-title":"Mol. Gen. Genet."},{"key":"BF00382276_CR22","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1128\/JB.132.3.870-875.1977","volume":"132","author":"J.M. Smith","year":"1977","unstructured":"Smith, J.M., Umbarger, H.E.: Characterization of fusions between the lac operon and the ilv gene cluster in Escherichia coli: ilvC-lac fusions. J. Bacteriol. 132, 870\u2013875 (1977)","journal-title":"J. Bacteriol."},{"key":"BF00382276_CR23","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0021-9258(17)41484-0","volume":"161","author":"W.W. Westerfeld","year":"1945","unstructured":"Westerfeld, W.W.: A colorimetric determination of blood acetoin. J. Biol. Chem. 161, 495\u2013502 (1945)","journal-title":"J. Biol. Chem."}],"container-title":["Molecular and General Genetics MGG"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00382276.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00382276\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00382276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00382276.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,27]],"date-time":"2021-06-27T21:07:45Z","timestamp":1624828065000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00382276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,1]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1979,1]]}},"alternative-id":["BF00382276"],"URL":"https:\/\/doi.org\/10.1007\/bf00382276","relation":{},"ISSN":["0026-8925","1432-1874"],"issn-type":[{"value":"0026-8925","type":"print"},{"value":"1432-1874","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,1]]}}}