{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T16:46:40Z","timestamp":1763830000857},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"2-3","license":[{"start":{"date-parts":[[1993,5,1]],"date-time":"1993-05-01T00:00:00Z","timestamp":736214400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioprocess Eng."],"published-print":{"date-parts":[[1993,5]]},"DOI":"10.1007\/bf00369042","type":"journal-article","created":{"date-parts":[[2004,11,2]],"date-time":"2004-11-02T18:22:52Z","timestamp":1099419772000},"page":"129-133","source":"Crossref","is-referenced-by-count":8,"title":["Optimum temperature policy for batch reactors performing biochemical reactions in the presence of enzyme deactivation"],"prefix":"10.1007","volume":"9","author":[{"given":"T. I.","family":"Lopes","sequence":"first","affiliation":[]},{"given":"F. X.","family":"Malcata","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0009-2509(56)80021-3","volume":"5","author":"O. Bilous","year":"1956","unstructured":"Bilous, O.; Amundson, N.R.: Optimal temperature gradient in tubular reactor ? I. General theory and methods. Chem. Eng. Sci. 5 (1956) 81","journal-title":"Chem. Eng. Sci."},{"key":"CR2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0009-2509(58)80043-3","volume":"8","author":"K. G. Denbigh","year":"1958","unstructured":"Denbigh, K. G.: Optimum temperature sequence in reactors, Chem. Eng. Sci. 8 (1958) 125","journal-title":"Eng. Sci."},{"key":"CR3","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1749-6632.1960.tb39085.x","volume":"84","author":"S. Katz","year":"1960","unstructured":"Katz, S.: Best temperature profiles in plug flow reactors: Methods of the calculus of variations. Ann. New York Acad. Sci. 84 (1960) 443","journal-title":"Ann. New York Acad. Sci."},{"key":"CR4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0009-2509(61)85055-0","volume":"14","author":"F. Horn","year":"1961","unstructured":"Horn, F.: Optimale temperatur und Konzentrationsverl\u00e4ufe, Chem. Eng. Sci. 14 (1961) 77","journal-title":"Eng. Sci."},{"key":"CR5","volume-title":"Ph. D. Thesis","author":"S. Szepe","year":"1966","unstructured":"Szepe, S.: The deactivation of catalysts and some related optimization problems. Ph. D. Thesis, III. Inst. Technol., Chicago (1966)"},{"key":"CR6","first-page":"T153","volume":"45","author":"A. Chou","year":"1967","unstructured":"Chou, A.; Ray, W. H.; Aris, R.: Simple control policy for reactors with catalyst decay. Trans. Inst. Chem. Eng. 45 (1967) T153","journal-title":"Trans. Inst. Chem. Eng."},{"key":"CR7","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/0009-2509(68)80022-3","volume":"23","author":"S. Szepe","year":"1968","unstructured":"Szepe, S.; Levenspiel, O.: Optimal temperature policies for reactors subject to catalyst deactivation ? I. Batch reactors. Chem. Eng. Sci. 23 (1968) 881","journal-title":"Chem. Eng. Sci."},{"key":"CR8","first-page":"T225","volume":"46","author":"A. F. Ogunye","year":"1968","unstructured":"Ogunye, A. F.; Ray, W. H.: Non-simple control policies for reactors with catalyst decay. Trans. Inst. Chem. Eng. 46 (1968) T225","journal-title":"Trans. Inst. Chem. Eng."},{"key":"CR9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/cjce.5450480516","volume":"48","author":"C. M. Crowe","year":"1970","unstructured":"Crowe, C. M.: Optimization of reactors with catalyst decay. I ? Single tubular reactor with uniform temperature. Can. J. Chem. Eng. 48 (1970) 576","journal-title":"Can. J. Chem. Eng."},{"key":"CR10","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/0009-2509(70)85105-3","volume":"25","author":"S. I. Lee","year":"1970","unstructured":"Lee, S. I.; Crowe, C. M.: Optimal temperature policies for batch reactors with decaying catalyst. Chem. Eng. Sci. 25 (1970a) 743","journal-title":"Chem. Eng. Sci."},{"key":"CR11","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/cjce.5450480217","volume":"48","author":"S. I. Lee","year":"1970","unstructured":"Lee, S. I.; Crowe, C. M.: The optimization of reactors with decaying catalyst. The effect of macromixing. Can. J. Chem. Eng. 48 (1970b) 192","journal-title":"Can. J. Chem. Eng."},{"key":"CR12","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/cjce.5450490315","volume":"49","author":"C. M. Crowe","year":"1971","unstructured":"Crowe, C. M.; Lee, S. I.: Optimization of reactors with catalyst decay. III ? Tubular reactor with several beds of uniform temperature. Can. J. Chem. Eng. 49 (1971) 385","journal-title":"Can. J. Chem. Eng."},{"key":"CR13","first-page":"533","volume":"15","author":"J. Y. Park","year":"1976","unstructured":"Park, J. Y.; Levenspiel, O.: Optimal operating cycle for systems with deactivating catalysts. 2. Applications to reactors. Ind. Eng. Chem. Process Design Develop. 15 (1976) 533","journal-title":"Ind. Eng. Chem. Process Design Develop."},{"key":"CR14","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/0009-2509(78)85122-7","volume":"33","author":"O. Levenspiel","year":"1978","unstructured":"Levenspiel, O.; Sadana, A.: The optimum temperature policy for a deactivating catalytic packed-bed reactor. Chem. Eng. Sci. 33 (1978) 1393","journal-title":"Chem. Eng. Sci."},{"key":"CR15","unstructured":"Drouin, J.-G.: Computational study of the optimization of a catalytic reactor for a reversible reaction with catalyst decay. M.Sc. Thesis, McMasters Univ. (1969)"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/aic.690200411","volume":"20","author":"W. R. Haas","year":"1974","unstructured":"Haas, W. R.; Tavlarides, L. L.; Wnek, W. J.: Optimal temperature policy for reversible reactions with deactivation: Applied to enzyme reactors. AIChE J. 20 (1974) 707","journal-title":"AIChE J."},{"key":"CR17","unstructured":"Chandra, K.; Pommersheim, J. M.: Optimal policies for deactivating batch reactor with conversion dependent catalyst decay. Presented at the 66th Annual AIChE Meeting, Philadelphia (1973)."},{"key":"CR18","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1002\/aic.690250320","volume":"25","author":"A. Sadana","year":"1979","unstructured":"Sadana, A.: A Generalized optimum temperature operations criterion for a deactivating immobilized enzyme batch reactor. AIChE J. 25 (1979) 535","journal-title":"AIChE J."},{"key":"CR19","first-page":"132","volume-title":"Biochemical Engineering Fundamentals","author":"J. E. Bailey","year":"1986","unstructured":"Bailey, J. E.; Ollis, D. F.: Biochemical Engineering Fundamentals, p. 132, McGraw-Hill, New York (1986)"},{"key":"CR20","first-page":"930","volume-title":"Enzyme Kinetics","author":"I. H. Segel","year":"1975","unstructured":"Segel, I. H.: Enzyme Kinetics, pp. 930?941, Wiley, New York (1975)"},{"key":"CR21","first-page":"489","volume-title":"Mathematical Methods for Science Students","author":"G. Stephenson","year":"1973","unstructured":"Stephenson, G.: Mathematical Methods for Science Students, p. 489, Longman, London (1973)"}],"container-title":["Bioprocess Engineering"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00369042.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF00369042\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00369042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T01:43:37Z","timestamp":1554774217000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF00369042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,5]]},"references-count":21,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[1993,5]]}},"alternative-id":["BF00369042"],"URL":"https:\/\/doi.org\/10.1007\/bf00369042","relation":{},"ISSN":["0178-515X","1615-7605"],"issn-type":[{"value":"0178-515X","type":"print"},{"value":"1615-7605","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,5]]}}}