{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:46:10Z","timestamp":1762659970750},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"28","license":[{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UIDB\/00709\/2020"],"award-info":[{"award-number":["UIDB\/00709\/2020"]}]},{"name":"Fundo Europeu de Desenvolvimento Regional (FEDER) through the Programa Operacional Regional Centro","award":["C4_WP2.6_M1 \u2013 Bioinformatics; Opera\u00e7\u00e3o UBIMEDI"],"award-info":[{"award-number":["C4_WP2.6_M1 \u2013 Bioinformatics; Opera\u00e7\u00e3o UBIMEDI"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1007\/s00216-020-02929-6","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T10:03:54Z","timestamp":1600769034000},"page":"7963-7976","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["New miniaturized clean-up procedure for hair samples by means of microextraction by packed sorbent: determination of cocaine and metabolites"],"prefix":"10.1007","volume":"412","author":[{"given":"Tiago","family":"Rosado","sequence":"first","affiliation":[]},{"given":"Eugenia","family":"Gallardo","sequence":"additional","affiliation":[]},{"given":"Duarte N.","family":"Vieira","sequence":"additional","affiliation":[]},{"given":"M\u00e1rio","family":"Barroso","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2020,9,22]]},"reference":[{"key":"2929_CR1","unstructured":"European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) (2019) EU Drug Markets Report. https:\/\/www.emcdda.europa.eu\/system\/files\/publications\/12078\/20192630_TD0319332ENN_PDF.pdf. Accessed 20 May 2020."},{"key":"2929_CR2","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.drugalcdep.2017.08.036","volume":"180","author":"AJ Butler","year":"2017","unstructured":"Butler AJ, Rehm J, Fischer B. Health outcomes associated with crack-cocaine use: systematic review and meta-analyses. Drug Alcohol Depend. 2017;180:401\u201316. https:\/\/doi.org\/10.1016\/j.drugalcdep.2017.08.036.","journal-title":"Drug Alcohol Depend"},{"key":"2929_CR3","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.forsciint.2004.02.027","volume":"142","author":"P Kintz","year":"2004","unstructured":"Kintz P. Value of hair analysis in postmortem toxicology. Forensic Sci Int. 2004;142:127\u201334. https:\/\/doi.org\/10.1016\/j.forsciint.2004.02.027.","journal-title":"Forensic Sci Int"},{"key":"2929_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4155\/bio.13.291","volume":"6","author":"M Barroso","year":"2014","unstructured":"Barroso M, Gallardo E. Hair analysis for forensic applications: is the future bright? Bioanalysis. 2014;6:1\u20133. https:\/\/doi.org\/10.4155\/bio.13.291.","journal-title":"Bioanalysis"},{"key":"2929_CR5","doi-asserted-by":"publisher","first-page":"4358","DOI":"10.1021\/ac049555t","volume":"76","author":"KB Scheidweiler","year":"2004","unstructured":"Scheidweiler KB, Huestis MA. Simultaneous quantification of opiates, cocaine, and metabolites in hair by LC-APCI-MS\/MS. Anal Chem. 2004;76:4358\u201363. https:\/\/doi.org\/10.1021\/ac049555t.","journal-title":"Anal Chem"},{"key":"2929_CR6","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0379-0738(00)00162-6","volume":"110","author":"KM Clauwaert","year":"2000","unstructured":"Clauwaert KM, Van Bocxlaer JF, Lambert WE, De Leenheer AP. Segmental analysis for cocaine and metabolites by HPLC in hair of suspected drug overdose cases. Forensic Sci Int. 2000;110:157\u201366. https:\/\/doi.org\/10.1016\/S0379-0738(00)00162-6.","journal-title":"Forensic Sci Int"},{"key":"2929_CR7","doi-asserted-by":"publisher","first-page":"67","DOI":"10.4155\/bio.10.171","volume":"3","author":"M Barroso","year":"2011","unstructured":"Barroso M, Gallardo E, Vieira DN, L\u00f3pez-Rivadulla M, Queiroz JA. Hair: a complementary source of bioanalytical information in forensic toxicology. Bioanalysis. 2011;3:67\u201379. https:\/\/doi.org\/10.4155\/bio.10.171.","journal-title":"Bioanalysis"},{"key":"2929_CR8","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.forsciint.2007.07.020","volume":"176","author":"C Hoelzle","year":"2008","unstructured":"Hoelzle C, Scheufler F, Uhl M, Sachs H, Thieme D. Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination. Forensic Sci Int. 2008;176:13\u20138. https:\/\/doi.org\/10.1016\/j.forsciint.2007.07.020.","journal-title":"Forensic Sci Int"},{"key":"2929_CR9","doi-asserted-by":"publisher","first-page":"437","DOI":"10.4155\/bio.14.291","volume":"7","author":"T Baciu","year":"2015","unstructured":"Baciu T, Borrull F, Calull M, Aguilar C. Determination of cocaine in abuser hairs by CE: monitoring compliance to a detoxification program. Bioanalysis. 2015;7:437\u201347. https:\/\/doi.org\/10.4155\/bio.14.291.","journal-title":"Bioanalysis"},{"key":"2929_CR10","doi-asserted-by":"publisher","first-page":"977","DOI":"10.4155\/bio.09.72","volume":"1","author":"M Barroso","year":"2009","unstructured":"Barroso M, Gallardo E, Queiroz JA. Bioanalytical methods for the determination of cocaine and metabolites in human biological samples. Bioanalysis. 2009;1:977\u20131000. https:\/\/doi.org\/10.4155\/bio.09.72.","journal-title":"Bioanalysis"},{"key":"2929_CR11","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.forsciint.2018.04.007","volume":"288","author":"T Franz","year":"2018","unstructured":"Franz T, Scheufler F, Stein K, Uhl M, Dame T, Schwarz G, et al. Determination of hydroxy metabolites of cocaine from hair samples and comparison with street cocaine samples. Forensic Sci Int. 2018;288:223\u20136. https:\/\/doi.org\/10.1016\/j.forsciint.2018.04.007.","journal-title":"Forensic Sci Int"},{"key":"2929_CR12","doi-asserted-by":"publisher","first-page":"6299","DOI":"10.1007\/s00216-013-7046-3","volume":"405","author":"MNR Alves","year":"2013","unstructured":"Alves MNR, Zanchetti G, Piccinotti A, Tameni S, De Martinis BS, Polettini A. Determination of cocaine and metabolites in hair by column-switching LC-MS-MS analysis. Anal Bioanal Chem. 2013;405:6299\u2013306. https:\/\/doi.org\/10.1007\/s00216-013-7046-3.","journal-title":"Anal Bioanal Chem"},{"key":"2929_CR13","first-page":"450","volume":"93","author":"T Gray","year":"2013","unstructured":"Gray T, Brace L, Shah S, Tolhurst T, Juhascik M, Negrusz A. Detection and quantitation of cocaine and metabolites in urine and hair after consumption of coca tea. Probl Forensic Sci. 2013;93:450\u201364.","journal-title":"Probl Forensic Sci"},{"key":"2929_CR14","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.forsciint.2011.05.007","volume":"215","author":"C Vignali","year":"2012","unstructured":"Vignali C, Stramesi C, Vecchio M, Groppi A. Hair testing and self-report of cocaine use. Forensic Sci Int. 2012;215:77\u201380. https:\/\/doi.org\/10.1016\/j.forsciint.2011.05.007.","journal-title":"Forensic Sci Int"},{"key":"2929_CR15","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1016\/j.jchromb.2009.04.035","volume":"877","author":"P Fern\u00e1ndez","year":"2009","unstructured":"Fern\u00e1ndez P, Lago M, Lorenzo RA, Carro AM, Bermejo AM, Tabernero MJ. Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair. J Chromatogr B Anal Technol Biomed Life Sci. 2009;877:1743\u201350. https:\/\/doi.org\/10.1016\/j.jchromb.2009.04.035.","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"2929_CR16","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.forsciint.2011.10.024","volume":"218","author":"GAA Cooper","year":"2012","unstructured":"Cooper GAA, Kronstrand R, Kintz P. Society of Hair Testing guidelines for drug testing in hair. Forensic Sci Int. 2012;218:20\u20134. https:\/\/doi.org\/10.1016\/j.forsciint.2011.10.024.","journal-title":"Forensic Sci Int"},{"key":"2929_CR17","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s00216-006-0721-x","volume":"387","author":"F David","year":"2007","unstructured":"David F, Van Hoeck E, Sandra P. Towards automated, miniaturized and solvent-free sample preparation methods. Anal Bioanal Chem. 2007;387:141\u20134. https:\/\/doi.org\/10.1007\/s00216-006-0721-x.","journal-title":"Anal Bioanal Chem"},{"key":"2929_CR18","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1002\/dta.1903","volume":"9","author":"C Gambelunghe","year":"2017","unstructured":"Gambelunghe C, Rossi R, Aroni K, Gili A, Bacci M, Pascali V, et al. Norcocaine and cocaethylene distribution patterns in hair samples from light, moderate, and heavy cocaine users. Drug Test Anal. 2017;9:161\u20137. https:\/\/doi.org\/10.1002\/dta.1903.","journal-title":"Drug Test Anal"},{"key":"2929_CR19","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1097\/FTD.0000000000000076","volume":"36","author":"N Fucci","year":"2014","unstructured":"Fucci N, Gambelunghe C, Aroni K, Rossi R. A direct immersion solid-phase microextraction gas chromatography\/mass spectrometry method for the simultaneous detection of levamisole and minor cocaine congeners in hair samples from chronic abusers. Ther Drug Monit. 2014;36:789\u201395. https:\/\/doi.org\/10.1097\/FTD.0000000000000076.","journal-title":"Ther Drug Monit"},{"key":"2929_CR20","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.forsciint.2014.05.019","volume":"241","author":"S Poon","year":"2014","unstructured":"Poon S, Gareri J, Walasek P, Koren G. Norcocaine in human hair as a biomarker of heavy cocaine use in a high risk population. Forensic Sci Int. 2014;241:150\u20134. https:\/\/doi.org\/10.1016\/j.forsciint.2014.05.019.","journal-title":"Forensic Sci Int"},{"key":"2929_CR21","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.forsciint.2011.10.002","volume":"218","author":"K Aleksa","year":"2012","unstructured":"Aleksa K, Walasek P, Fulga N, Kapur B, Gareri J, Koren G. Simultaneous detection of seventeen drugs of abuse and metabolites in hair using solid phase micro extraction (SPME) with GC\/MS. Forensic Sci Int. 2012;218:31\u20136. https:\/\/doi.org\/10.1016\/j.forsciint.2011.10.002.","journal-title":"Forensic Sci Int"},{"key":"2929_CR22","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.trac.2012.10.006","volume":"43","author":"EAS Silva","year":"2013","unstructured":"Silva EAS, Risticevic S, Pawliszyn J. Recent trends in SPME concerning sorbent materials, configurations and in vivo applications. TrAC Trends Anal Chem. 2013;43:24\u201336. https:\/\/doi.org\/10.1016\/j.trac.2012.10.006.","journal-title":"TrAC Trends Anal Chem"},{"key":"2929_CR23","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.forsciint.2016.12.024","volume":"274","author":"AMF Pego","year":"2017","unstructured":"Pego AMF, Roveri FL, Kuninari RY, Leyton V, Miziara ID, Yonamine M. Determination of cocaine and its derivatives in hair samples by liquid phase microextraction (LPME) and gas chromatography\u2013mass spectrometry (GC\u2013MS). Forensic Sci Int. 2017;274:83\u201390. https:\/\/doi.org\/10.1016\/j.forsciint.2016.12.024.","journal-title":"Forensic Sci Int"},{"key":"2929_CR24","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.trac.2014.12.003","volume":"67","author":"M Mahdi","year":"2015","unstructured":"Mahdi M, Abdel-rehim A, Abdel-rehim M. Trends in analytical chemistry microextraction by packed sorbent (MEPS). Trends Anal Chem. 2015;67:34\u201344. https:\/\/doi.org\/10.1016\/j.trac.2014.12.003.","journal-title":"Trends Anal Chem"},{"key":"2929_CR25","doi-asserted-by":"publisher","first-page":"4063","DOI":"10.1016\/j.chroma.2009.02.093","volume":"1216","author":"H Miyaguchi","year":"2009","unstructured":"Miyaguchi H, Iwata YT, Kanamori T, Tsujikawa K, Kuwayama K, Inoue H. Rapid identification and quantification of methamphetamine and amphetamine in hair by gas chromatography\/mass spectrometry coupled with micropulverized extraction, aqueous acetylation and microextraction by packed sorbent. J Chromatogr A. 2009;1216:4063\u201370. https:\/\/doi.org\/10.1016\/j.chroma.2009.02.093.","journal-title":"J Chromatogr A"},{"key":"2929_CR26","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1093\/jat\/bkz029","volume":"43","author":"E Gallardo","year":"2019","unstructured":"Gallardo E, Rosado T, Barroso M, Vieira DN. Determination of selected opiates in hair samples using microextraction by packed sorbent: a new approach for sample clean-up. J Anal Toxicol. 2019;43:465\u201376. https:\/\/doi.org\/10.1093\/jat\/bkz029.","journal-title":"J Anal Toxicol"},{"key":"2929_CR27","doi-asserted-by":"publisher","unstructured":"Rosado T, Gallardo E, Vieira DN, Barroso M. Microextraction by packed sorbent as a novel strategy for sample clean-up in the determination of methadone and Eddp in hair. J Anal Toxicol. 2020. https:\/\/doi.org\/10.1093\/jat\/bkaa040.","DOI":"10.1093\/jat\/bkaa040"},{"key":"2929_CR28","unstructured":"Food and Drug Administration (2018) Bioanalytical Method Validation Guidance for Industry. https:\/\/www.fda.gov\/files\/drugs\/published\/Bioanalytical-Method-Validation-Guidance-for-Industry.pdf. Accessed 20 May 2020."},{"key":"2929_CR29","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1093\/jat\/bkt054","volume":"37","author":"Scientific Working Group for Forensic Toxicology","year":"2013","unstructured":"Scientific Working Group for Forensic Toxicology. Scientific Working Group for Forensic Toxicology (SWGTOX) standard practices for method validation in forensic toxicology. J Anal Toxicol. 2013;37:452\u201374. https:\/\/doi.org\/10.1093\/jat\/bkt054.","journal-title":"J Anal Toxicol"},{"key":"2929_CR30","doi-asserted-by":"publisher","unstructured":"Rosado T, Gon\u00e7alves A, Margalho C, Barroso M, Gallardo E (2017) Rapid analysis of cocaine and metabolites in urine using microextraction in packed sorbent and GC\/MS. Anal Bioanal Chem 409. https:\/\/doi.org\/10.1007\/s00216-016-0152-2.","DOI":"10.1007\/s00216-016-0152-2"},{"key":"2929_CR31","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jchromb.2005.07.043","volume":"826","author":"E Cognard","year":"2005","unstructured":"Cognard E, Rudaz S, Bouchonnet S, Staub C. Analysis of cocaine and three of its metabolites in hair by gas chromatography-mass spectrometry using ion-trap detection for CI\/MS\/MS. J Chromatogr B Anal Technol Biomed Life Sci. 2005;826:17\u201325. https:\/\/doi.org\/10.1016\/j.jchromb.2005.07.043.","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"2929_CR32","unstructured":"World Anti-Doping Agency (2015) Minimum criteria for chromatographic-mass spectrometric confirmation of the identity of analytes for doping control purposes. https:\/\/www.wada-ama.org\/sites\/default\/files\/resources\/files\/td2015idcr_-_eng.pdf. Accessed 8 Jan 2018."},{"key":"2929_CR33","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1002\/dta.1999","volume":"8","author":"A Salomone","year":"2016","unstructured":"Salomone A, Tsanaclis L, Agius R, Kintz P, Baumgartner MR. European guidelines for workplace drug and alcohol testing in hair. Drug Test Anal. 2016;8:996\u20131004. https:\/\/doi.org\/10.1002\/dta.1999.","journal-title":"Drug Test Anal"},{"key":"2929_CR34","doi-asserted-by":"publisher","first-page":"2987","DOI":"10.1007\/s00216-010-3882-6","volume":"397","author":"G Merola","year":"2010","unstructured":"Merola G, Gentili S, Tagliaro F, MacChia T. Determination of different recreational drugs in hair by HS-SPME and GC\/MS. Anal Bioanal Chem. 2010;397:2987\u201395. https:\/\/doi.org\/10.1007\/s00216-010-3882-6.","journal-title":"Anal Bioanal Chem"},{"key":"2929_CR35","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.jchromb.2003.11.034","volume":"801","author":"S Gentili","year":"2004","unstructured":"Gentili S, Cornetta M, Macchia T. Rapid screening procedure based on headspace solid-phase microextraction and gas chromatography-mass spectrometry for the detection of many recreational drugs in hair. J Chromatogr B Anal Technol Biomed Life Sci. 2004;801:289\u201396. https:\/\/doi.org\/10.1016\/j.jchromb.2003.11.034.","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"2929_CR36","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1080\/00085030.2007.10757156","volume":"40","author":"S Schiavone","year":"2007","unstructured":"Schiavone S, Marsili R, Iuliano G, Ghizzoni O, Chiarotti M. Cocaine analysis in hair: solid-phase microextraction (SPME) versus supercritical fluid extraction (SFE). J Can Soc Forensic Sci. 2007;40:143\u20139. https:\/\/doi.org\/10.1080\/00085030.2007.10757156.","journal-title":"J Can Soc Forensic Sci"},{"key":"2929_CR37","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.forsciint.2005.09.007","volume":"156","author":"AM Bermejo","year":"2006","unstructured":"Bermejo AM, L\u00f3pez P, \u00c1lvarez I, Tabernero MJ, Fern\u00e1ndez P. Solid-phase microextraction for the determination of cocaine and cocaethylene in human hair by gas chromatography-mass spectrometry. Forensic Sci Int. 2006;156:2\u20138. https:\/\/doi.org\/10.1016\/j.forsciint.2005.09.007.","journal-title":"Forensic Sci Int"},{"key":"2929_CR38","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1002\/jat.1054","volume":"25","author":"C Gambelunghe","year":"2005","unstructured":"Gambelunghe C, Rossi R, Ferranti C, Rossi R, Bacci M. Hair analysis by GC\/MS\/MS to verify abuse of drugs. J Appl Toxicol. 2005;25:205\u201311. https:\/\/doi.org\/10.1002\/jat.1054.","journal-title":"J Appl Toxicol"},{"key":"2929_CR39","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/S0379-0738(99)00161-9","volume":"107","author":"M Uhl","year":"2000","unstructured":"Uhl M. Tandem mass spectrometry: a helpful tool in hair analysis for the forensic expert. Forensic Sci Int. 2000;107:169\u201379. https:\/\/doi.org\/10.1016\/S0379-0738(99)00161-9.","journal-title":"Forensic Sci Int"},{"key":"2929_CR40","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1093\/jat\/23.5.343","volume":"23","author":"S Pichini","year":"1999","unstructured":"Pichini S, Pacifici R, Altieri I, Pellegrini M, Zuccaro P. Determination of opiates and cocaine in hair as trimethylsilyl derivatives using gas chromatography-tandem mass spectrometry. J Anal Toxicol. 1999;23:343\u20138. https:\/\/doi.org\/10.1093\/jat\/23.5.343.","journal-title":"J Anal Toxicol"},{"key":"2929_CR41","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0379-0738(96)02051-8","volume":"84","author":"DA Kidwell","year":"1997","unstructured":"Kidwell DA, Blanco MA, Smith FP. Cocaine detection in a university population by hair analysis and skin swab testing. Forensic Sci Int. 1997;84:75\u201386. https:\/\/doi.org\/10.1016\/S0379-0738(96)02051-8.","journal-title":"Forensic Sci Int"},{"key":"2929_CR42","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1002\/dta.2317","volume":"10","author":"F Musshoff","year":"2018","unstructured":"Musshoff F, Thieme D, Schwarz G, Sachs H, Skopp G, Franz T. Determination of hydroxy metabolites of cocaine in hair samples for proof of consumption. Drug Test Anal. 2018;10:681\u20138. https:\/\/doi.org\/10.1002\/dta.2317.","journal-title":"Drug Test Anal"},{"key":"2929_CR43","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.jchromb.2014.05.055","volume":"965","author":"MR Fern\u00e1ndez M del","year":"2014","unstructured":"Fern\u00e1ndez M del MR, Di Fazio V, Wille SMR, Kummer N, Samyn N. A quantitative, selective and fast ultra-high performance liquid chromatography tandem mass spectrometry method for the simultaneous analysis of 33 basic drugs in hair (amphetamines, cocaine, opiates, opioids and metabolites). J Chromatogr B Anal Technol Biomed Life Sci. 2014;965:7\u201318. https:\/\/doi.org\/10.1016\/j.jchromb.2014.05.055.","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"2929_CR44","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1007\/s00216-016-9354-x","volume":"408","author":"M Schaffer","year":"2016","unstructured":"Schaffer M, Cheng CC, Chao O, Hill V, Matsui P. Analysis of cocaine and metabolites in hair: validation and application of measurement of hydroxycocaine metabolites as evidence of cocaine ingestion. Anal Bioanal Chem. 2016;408:2043\u201354. https:\/\/doi.org\/10.1007\/s00216-016-9354-x.","journal-title":"Anal Bioanal Chem"},{"key":"2929_CR45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13065-014-0073-0","volume":"8","author":"I Shah","year":"2014","unstructured":"Shah I, Petroczi A, Uvacsek M, R\u00e1nky M, Naughton DP. Hair-based rapid analyses for multiple drugs in forensics and doping: application of dynamic multiple reaction monitoring with LC-MS\/MS. Chem Cent J. 2014;8:1\u201310. https:\/\/doi.org\/10.1186\/s13065-014-0073-0.","journal-title":"Chem Cent J"},{"key":"2929_CR46","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.forsciint.2013.11.004","volume":"234","author":"L Imbert","year":"2014","unstructured":"Imbert L, Dulaurent S, Mercerolle M, Morichon J, Lach\u00e2tre G, Gaulier JM. Development and validation of a single LC-MS\/MS assay following SPE for simultaneous hair analysis of amphetamines, opiates, cocaine and metabolites. Forensic Sci Int. 2014;234:132\u20138. https:\/\/doi.org\/10.1016\/j.forsciint.2013.11.004.","journal-title":"Forensic Sci Int"},{"key":"2929_CR47","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1093\/jat\/24.7.489","volume":"24","author":"JA Bourland","year":"2000","unstructured":"Bourland JA, Hayes EF, Kelly RC, Sweeney SA, Hatab MM. Quantification of cocaine, benzoylecgonine, cocaethylene, methylecgonine, and norcocaine in human hair by positive ion chemical ionization (PICI) gas chromatography-tandem mass spectrometry. J Anal Toxicol. 2000;24:489\u201395. https:\/\/doi.org\/10.1093\/jat\/24.7.489.","journal-title":"J Anal Toxicol"},{"key":"2929_CR48","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1007\/s00216-009-3393-5","volume":"396","author":"O Quintela","year":"2010","unstructured":"Quintela O, Lendoiro E, Cruz A, de Castro A, Quevedo A, Jurado C, et al. Hydrophilic interaction liquid chromatography\u2013tandem mass spectrometry (HILIC-MS\/MS) determination of cocaine and its metabolites benzoylecgonine, ecgonine methyl ester, and cocaethylene in hair samples. Anal Bioanal Chem. 2010;396:1703\u201312. https:\/\/doi.org\/10.1007\/s00216-009-3393-5.","journal-title":"Anal Bioanal Chem"},{"key":"2929_CR49","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1093\/jat\/19.6.479","volume":"19","author":"P Kintz","year":"1995","unstructured":"Kintz P, Cirimele V, Sengler C, Mangin P. Testing human hair and urine for anhydroecgonine methyl ester, a pyrolysis product of cocaine. J Anal Toxicol. 1995;19:479\u201382. https:\/\/doi.org\/10.1093\/jat\/19.6.479.","journal-title":"J Anal Toxicol"},{"key":"2929_CR50","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/0379-0738(95)01725-X","volume":"73","author":"P Kintz","year":"1995","unstructured":"Kintz P, Mangin P. Simultaneous determination of opiates, cocaine and major metabolites of cocaine in human hair by gas chromotography\/mass spectrometry (GC\/MS). Forensic Sci Int. 1995;73:93\u2013100. https:\/\/doi.org\/10.1016\/0379-0738(95)01725-X.","journal-title":"Forensic Sci Int"},{"key":"2929_CR51","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1093\/jat\/16.5.291","volume":"16","author":"MR M\u00f6ller","year":"1992","unstructured":"M\u00f6ller MR, Fey P, Rimbach S. Identification and quantitation of cocaine and its metabolites, benzoylecgonine and ecgonine methyl ester, in hair of Bolivian coca chewers by gas chromatography\/mass spectrometry. J Anal Toxicol. 1992;16:291\u20136. https:\/\/doi.org\/10.1093\/jat\/16.5.291.","journal-title":"J Anal Toxicol"},{"key":"2929_CR52","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.jchromb.2003.10.008","volume":"798","author":"FC Pereira De Toledo","year":"2003","unstructured":"Pereira De Toledo FC, Yonamine M, De Moraes Moreau RL, Silva OA. Determination of cocaine, benzoylecgonine and cocaethylene in human hair by solid-phase microextraction and gas chromatography-mass spectrometry. J Chromatogr B Anal Technol Biomed Life Sci. 2003;798:361\u20135. https:\/\/doi.org\/10.1016\/j.jchromb.2003.10.008.","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"2929_CR53","first-page":"466","volume":"19","author":"A Natekar","year":"2012","unstructured":"Natekar A, Matok I, Walasek P, Rao C, Clare-Fasullo G, Koren G. Cocaethylene as a hair biomarker to predict heavy alcohol exposure among cocaine users. J Popul Ther Clin Pharmacol. 2012;19:466\u201372.","journal-title":"J Popul Ther Clin Pharmacol"},{"key":"2929_CR54","doi-asserted-by":"publisher","first-page":"3320","DOI":"10.1002\/rcm.3738","volume":"22","author":"M Barroso","year":"2008","unstructured":"Barroso M, Dias M, Vieira DN, Queiroz JA, L\u00f3pez-Rivadulla M. Development and validation of an analytical method for the simultaneous determination of cocaine and its main metabolite, benzoylecgonine, in human hair by gas chromatography\/mass spectrometry. Rapid Commun Mass Spectrom An Int J Devoted to Rapid Dissem Up-to-the-Minute Res Mass Spectrom. 2008;22:3320\u20136. https:\/\/doi.org\/10.1002\/rcm.3738.","journal-title":"Rapid Commun Mass Spectrom An Int J Devoted to Rapid Dissem Up-to-the-Minute Res Mass Spectrom"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-020-02929-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00216-020-02929-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-020-02929-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:17:29Z","timestamp":1632269849000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00216-020-02929-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,22]]},"references-count":54,"journal-issue":{"issue":"28","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["2929"],"URL":"https:\/\/doi.org\/10.1007\/s00216-020-02929-6","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,22]]},"assertion":[{"value":"5 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"This study was conducted according to ethical standards and was approved by the ethics committee from Casas de Santiago. All analyses were carried out according to the ethical standards of the institution, and the analyzed samples were obtained from individuals who provided informed consent for their use (including the drug-free samples used in the validation experiments, provided by laboratory staff).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}