{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T16:01:20Z","timestamp":1776960080085,"version":"3.51.4"},"reference-count":114,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Membrane Biol"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1007\/s00232-010-9294-x","type":"journal-article","created":{"date-parts":[[2010,8,9]],"date-time":"2010-08-09T06:38:18Z","timestamp":1281335898000},"page":"215-224","source":"Crossref","is-referenced-by-count":101,"title":["Tubular Fluid Secretion in the Seminiferous Epithelium: Ion Transporters and Aquaporins in Sertoli Cells"],"prefix":"10.1007","volume":"236","author":[{"given":"Lu\u00eds","family":"Rato","sequence":"first","affiliation":[]},{"given":"S\u00edlvia","family":"Socorro","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9 E. B.","family":"Cavaco","sequence":"additional","affiliation":[]},{"given":"Pedro F.","family":"Oliveira","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2010,8,10]]},"reference":[{"key":"9294_CR1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1113\/jphysiol.2002.020818","volume":"542","author":"P Agre","year":"2002","unstructured":"Agre P, King LS, Yasui M, Guggino WB, Ottersen OP, Fujiyoshi Y, Engel A, Nielsen S (2002) Aquaporin water channels\u2014from atomic structure to clinical medicine. J Physiol 542:3\u201316","journal-title":"J Physiol"},{"key":"9294_CR2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1113\/jphysiol.1980.sp013517","volume":"309","author":"C Au","year":"1980","unstructured":"Au C, Wong P (1980) Luminal acidification by the perfused rat cauda epididymidis. J Physiol 309:419","journal-title":"J Physiol"},{"key":"9294_CR3","doi-asserted-by":"crossref","first-page":"19230","DOI":"10.1074\/jbc.M301096200","volume":"278","author":"C Auzanneau","year":"2003","unstructured":"Auzanneau C, Thoreau V, Kitzis A, Becq F (2003) A novel voltage-dependent chloride current activated by extracellular acidic pH in cultured rat Sertoli cells. J Biol Chem 278:19230\u201319236","journal-title":"J Biol Chem"},{"key":"9294_CR4","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.bcp.2007.09.004","volume":"75","author":"C Auzanneau","year":"2008","unstructured":"Auzanneau C, Norez C, Antigny F, Thoreau V, Jougla C, Cantereau A, Becq F, Vandebrouck C (2008) Transient receptor potential vanilloid 1 (TRPV1) channels in cultured rat Sertoli cells regulate an acid sensing chloride channel. Biochem Pharmacol 75:476\u2013483","journal-title":"Biochem Pharmacol"},{"key":"9294_CR5","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1146\/annurev.physiol.60.1.667","volume":"60","author":"A Babenko","year":"1998","unstructured":"Babenko A, Aguilar-Bryan L, Bryan J (1998) A view of sur\/KIR6. X, KATP channels. Annu Rev Physiol 60:667\u2013687","journal-title":"Annu Rev Physiol"},{"key":"9294_CR6","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/j.1939-4640.2002.tb02243.x","volume":"23","author":"HH Badran","year":"2002","unstructured":"Badran HH, Hermo LS (2002) Expression and regulation of aquaporins 1, 8, and 9 in the testis, efferent ducts, and epididymis of adult rats and during postnatal development. J Androl 23:358\u2013373","journal-title":"J Androl"},{"key":"9294_CR7","doi-asserted-by":"crossref","first-page":"4820","DOI":"10.1167\/iovs.02-1317","volume":"44","author":"LE Ball","year":"2003","unstructured":"Ball LE, Little M, Nowak MW, Garland DL, Crouch RK, Schey KL (2003) Water permeability of C-terminally truncated aquaporin 0 (AQP0 1\u2013243) observed in the aging human lens. Invest Ophthalmol Vis Sci 44:4820\u20134828","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9294_CR8","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/0092-8674(92)90155-6","volume":"68","author":"C Bear","year":"1992","unstructured":"Bear C, Li C, Kartner N, Bridges R, Jensen T, Ramjeesingh M, Riordan J (1992) Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR). Cell 68:809\u2013818","journal-title":"Cell"},{"key":"9294_CR9","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1152\/physrev.1999.79.3.763","volume":"79","author":"MP Blaustein","year":"1999","unstructured":"Blaustein MP, Lederer WJ (1999) Sodium\/calcium exchange: its physiological implications. Physiol Rev 79:763\u2013854","journal-title":"Physiol Rev"},{"key":"9294_CR10","doi-asserted-by":"crossref","first-page":"C922","DOI":"10.1152\/ajpcell.1998.274.4.C922","volume":"274","author":"FR Boockfor","year":"1998","unstructured":"Boockfor FR, Morris RA, DeSimone DC, Hunt DM, Walsh KB (1998) Sertoli cell expression of the cystic fibrosis transmembrane conductance regulator. Am J Physiol Cell Physiol 274:C922\u2013C930","journal-title":"Am J Physiol Cell Physiol"},{"key":"9294_CR11","first-page":"176","volume":"2","author":"WF Boron","year":"2001","unstructured":"Boron WF (2001) Sodium-coupled bicarbonate transporters. J Pancreas 2:176\u2013181","journal-title":"J Pancreas"},{"key":"9294_CR12","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1152\/advan.00045.2004","volume":"28","author":"W Boron","year":"2004","unstructured":"Boron W (2004) Regulation of intracellular pH. Am J Physiol Adv Physiol Educ 28:160\u2013179","journal-title":"Am J Physiol Adv Physiol Educ"},{"key":"9294_CR13","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1242\/jeb.028563","volume":"212","author":"W Boron","year":"2009","unstructured":"Boron W, Chen L, Parker M (2009) Modular structure of sodium-coupled bicarbonate transporters. J Exp Biol 212:1697","journal-title":"J Exp Biol"},{"key":"9294_CR14","first-page":"264","volume":"61","author":"D Brown","year":"1993","unstructured":"Brown D, Verbavatz J, Valenti G, Lui B, Sabolic I (1993) Localization of the CHIP28 water channel in reabsorptive segments of the rat male reproductive tract. Eur J Cell Biol 61:264\u2013273","journal-title":"Eur J Cell Biol"},{"key":"9294_CR15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/aja.1001880105","volume":"188","author":"S Byers","year":"1990","unstructured":"Byers S, Graham R (1990) Distribution of sodium\u2013potassium ATPase in the rat testis and epididymis. Am J Anat 188:31\u201343","journal-title":"Am J Anat"},{"key":"9294_CR16","doi-asserted-by":"crossref","first-page":"E143","DOI":"10.1152\/ajpendo.1990.258.1.E143","volume":"258","author":"C Caflisch","year":"1990","unstructured":"Caflisch C, DuBose T Jr (1990) Direct evaluation of acidification by rat testis and epididymis: role of carbonic anhydrase. Am J Physiol Endocrinol Metab 258:E143","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"9294_CR17","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1016\/S0021-9258(18)45848-6","volume":"267","author":"E Carafoli","year":"1992","unstructured":"Carafoli E (1992) The Ca2+ pump of the plasma membrane. J Biol Chem 267:2115\u20132118","journal-title":"J Biol Chem"},{"key":"9294_CR18","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/jcp.20952","volume":"211","author":"S Catalano","year":"2007","unstructured":"Catalano S, Rizza P, Gu G, Barone I, Giordano C, Marsico S, Casaburi I, Middea E, Lanzino M, Pellegrino M, Ando S (2007) Fas ligand expression in TM4 Sertoli cells is enhanced by estradiol \u201cin situ\u201d production. J Cell Physiol 211:448\u2013456","journal-title":"J Cell Physiol"},{"key":"9294_CR19","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1095\/biolreprod.104.031401","volume":"71","author":"J Clulow","year":"2004","unstructured":"Clulow J, Jones R (2004) Composition of luminal fluid secreted by the seminiferous tubules and after reabsorption by the extratesticular ducts of the Japanese quail, Coturnix coturnix japonica. Biol Reprod 71:1508","journal-title":"Biol Reprod"},{"key":"9294_CR20","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1095\/biolreprod46.3.414","volume":"46","author":"A D\u2019Agostino","year":"1992","unstructured":"D\u2019Agostino A, Mene P, Stefanini M (1992) Voltage-gated calcium channels in rat Sertoli cells. Biol Reprod 46:414\u2013418","journal-title":"Biol Reprod"},{"key":"9294_CR21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1152\/physrev.00028.2002","volume":"83","author":"T Decoursey","year":"2003","unstructured":"Decoursey T (2003) Voltage-gated proton channels and other proton transfer pathways. Physiol Rev 83:475","journal-title":"Physiol Rev"},{"key":"9294_CR22","doi-asserted-by":"crossref","first-page":"25677","DOI":"10.1016\/S0021-9258(18)47302-4","volume":"269","author":"E Delpire","year":"1994","unstructured":"Delpire E, Rauchman M, Beier D, Hebert S, Gullans S (1994) Molecular cloning and chromosome localization of a putative basolateral Na+-K+-2Cl-cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells. J Biol Chem 269:25677","journal-title":"J Biol Chem"},{"key":"9294_CR23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0304-4157(91)90012-L","volume":"1071","author":"M Dunne","year":"1991","unstructured":"Dunne M, Petersen O (1991) Potassium selective ion channels in insulin-secreting cells: physiology, pharmacology and their role in stimulus\u2013secretion coupling. Biochim Biophys Acta Rev Biomembr 1071:67\u201382","journal-title":"Biochim Biophys Acta Rev Biomembr"},{"key":"9294_CR24","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/biolreprod\/3.3.308","volume":"3","author":"M Dym","year":"1970","unstructured":"Dym M, Fawcett D (1970) The blood\u2013testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol Reprod 3:308\u2013326","journal-title":"Biol Reprod"},{"key":"9294_CR25","doi-asserted-by":"crossref","first-page":"F1047","DOI":"10.1152\/ajprenal.0158.2001","volume":"281","author":"M-L Elkjar","year":"2001","unstructured":"Elkjar M-L, Nejsum LN, Gresz V, Kwon T-H, Jensen UB, Frokiar J, Nielsen S (2001) Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways. Am J Physiol Renal Physiol 281:F1047\u2013F1057","journal-title":"Am J Physiol Renal Physiol"},{"key":"9294_CR26","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/jemt.20329","volume":"69","author":"H Feng","year":"2006","unstructured":"Feng H, Hershlag A, Han Y, Zheng L (2006) Localizations of intracellular calcium and Ca 2-ATPase in hamster spermatogenic cells and spermatozoa. Microsc Res Tech 69:618\u2013623","journal-title":"Microsc Res Tech"},{"key":"9294_CR27","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1113\/jphysiol.2002.018648","volume":"542","author":"D Fisher","year":"2002","unstructured":"Fisher D (2002) New light shed on fluid formation in the seminiferous tubules of the rat. J Physiol 542:445\u2013452","journal-title":"J Physiol"},{"key":"9294_CR28","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0960-0760(92)90079-X","volume":"43","author":"G Forti","year":"1992","unstructured":"Forti G, Vannelli G, Barni T, Balboni G, Orlando C, Serio M (1992) Sertoli\u2013germ cells interactions in the human testis. J Steroid Biochem Mol Biol 43:419\u2013422","journal-title":"J Steroid Biochem Mol Biol"},{"key":"9294_CR29","doi-asserted-by":"crossref","first-page":"23739","DOI":"10.1016\/S0021-9258(18)54345-3","volume":"266","author":"E Gorczynska","year":"1991","unstructured":"Gorczynska E, Handelsman D (1991) The role of calcium in follicle-stimulating hormone signal transduction in Sertoli cells. J Biol Chem 266:23739","journal-title":"J Biol Chem"},{"key":"9294_CR30","doi-asserted-by":"crossref","first-page":"E863","DOI":"10.1152\/ajpendo.1993.264.6.E863","volume":"264","author":"E Gorczynska","year":"1993","unstructured":"Gorczynska E, Handelsman DJ (1993) Requirement for transmembrane sodium flux in maintenance of cytosolic calcium levels in rat Sertoli cells. Am J Physiol Endocrinol Metab 264:E863\u2013E867","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"9294_CR31","first-page":"219","volume":"4","author":"E Gorczy\u0144ska-Fj\u00e4lling","year":"2004","unstructured":"Gorczy\u0144ska-Fj\u00e4lling E (2004) The role of calcium in signal transduction processes in Sertoli cells. Reprod Biol 4:219\u2013241","journal-title":"Reprod Biol"},{"key":"9294_CR32","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0092-8674(84)90190-9","volume":"39","author":"M Gorin","year":"1984","unstructured":"Gorin M, Yancey S, Cline J, Revel J, Horwitz J (1984) The major intrinsic protein (MIP) of the bovine lens fiber membrane: characterization and structure based on cDNA cloning. Cell 39:49\u201359","journal-title":"Cell"},{"key":"9294_CR33","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1210\/endo-128-1-158","volume":"128","author":"P Grasso","year":"1991","unstructured":"Grasso P, Joseph MP, Reichert LE Jr (1991) A new role for follicle-stimulating hormone in the regulation of calcium flux in Sertoli cells: inhibition of Na+\/Ca2+ exchange. Endocrinology 128:158\u2013164","journal-title":"Endocrinology"},{"key":"9294_CR34","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/aja.1001470403","volume":"147","author":"C Gravis","year":"1976","unstructured":"Gravis C, Yates R, Chen I (1976) Light and electron microscopic localization of ATPase in normal and degenerating testes of Syrian hamsters. Am J Anat 147:419\u2013431","journal-title":"Am J Anat"},{"key":"9294_CR35","first-page":"411","volume-title":"The central role of Sertoli cells in spermatogenesis","author":"M Griswold","year":"1998","unstructured":"Griswold M (1998) The central role of Sertoli cells in spermatogenesis. Academic Press, London, pp 411\u2013416"},{"key":"9294_CR36","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1007\/BF02138866","volume":"27","author":"R Henning","year":"1971","unstructured":"Henning R, Young J (1971) Electrolyte transport in the seminiferous tubules of the rat studied by the stopped-flow microperfusion technique. Cell Mol Life Sci 27:1037\u20131039","journal-title":"Cell Mol Life Sci"},{"key":"9294_CR37","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1095\/biolreprod64.6.1699","volume":"64","author":"CM Herak-Kramberger","year":"2001","unstructured":"Herak-Kramberger CM, Breton S, Brown D, Kraus O, Sabolic I (2001) Distribution of the vacuolar H+ATPase along the rat and human male reproductive tract. Biol Reprod 64:1699\u20131707","journal-title":"Biol Reprod"},{"key":"9294_CR38","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/j.1939-4640.2004.tb02820.x","volume":"25","author":"L Hermo","year":"2004","unstructured":"Hermo L, Krzeczunowicz D, Ruz R (2004) Cell specificity of aquaporins 0, 3, and 10 expressed in the testis, efferent ducts, and epididymis of adult rats. J Androl 25:494\u2013505","journal-title":"J Androl"},{"key":"9294_CR39","first-page":"249","volume-title":"The Sertoli cell","author":"B Hinton","year":"1993","unstructured":"Hinton B, Setchell B (1993) Fluid secretion and movement. In: Russell L, Griswold M (eds) The Sertoli cell. Cache River Press, Clearwater, FL, pp 249\u2013267"},{"key":"9294_CR40","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1093\/humupd\/dml035","volume":"12","author":"H-F Huang","year":"2006","unstructured":"Huang H-F, He R-H, Sun C-C, Zhang Y, Meng Q-X, Ma Y-Y (2006) Function of aquaporins in female and male reproductive systems. Hum Reprod Update 12:785\u2013795","journal-title":"Hum Reprod Update"},{"key":"9294_CR41","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1093\/hmg\/11.20.2435","volume":"11","author":"C Hubner","year":"2002","unstructured":"Hubner C, Jentsch T (2002) Ion channel diseases. Hum Mol Genet 11:2435","journal-title":"Hum Mol Genet"},{"key":"9294_CR42","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1254\/jphs.CRJ06007X","volume":"100","author":"Y Ishikawa","year":"2006","unstructured":"Ishikawa Y, Cho G, Yuan Z, Skowronski M, Pan Y, Ishida H (2006) Water channels and zymogen granules in salivary glands. J Pharmacol Sci 100:495\u2013512","journal-title":"J Pharmacol Sci"},{"key":"9294_CR43","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1055\/s-2005-861414","volume":"37","author":"A Jacobus","year":"2005","unstructured":"Jacobus A, Rodrigues D, Borba P, Loss E, Wassermann G (2005) Isoproterenol opens K+(ATP) channels via a beta2-adrenoceptor-linked mechanism in Sertoli cells from immature rats. Horm Metab Res 37:198\u2013204","journal-title":"Horm Metab Res"},{"key":"9294_CR44","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0074-7696(08)60766-4","volume":"147","author":"B Jegou","year":"1993","unstructured":"Jegou B (1993) The Sertoli\u2013germ cell communication network in mammals. Int Rev Cytol 147:25\u201396","journal-title":"Int Rev Cytol"},{"key":"9294_CR45","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1095\/biolreprod27.3.590","volume":"27","author":"B Jegou","year":"1982","unstructured":"Jegou B, Le Gac F, de Kretser D (1982) Seminiferous tubule fluid and interstitial fluid production. I. Effects of age and hormonal regulation in immature rats. Biol Reprod 27:590\u2013595","journal-title":"Biol Reprod"},{"key":"9294_CR46","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1365-2605.1983.tb00539.x","volume":"6","author":"B Jegou","year":"1983","unstructured":"Jegou B, Le Gac F, Irby DC, de Kretser DM (1983) Studies on seminiferous tubule fluid production in the adult rat: effect of hypophysectomy and treatment with FSH, LH and testosterone. Int J Androl 6:249\u2013260","journal-title":"Int J Androl"},{"key":"9294_CR47","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1095\/biolreprod23.5.981","volume":"23","author":"AD Jenkins","year":"1980","unstructured":"Jenkins AD, Lechene CP, Howards SS (1980) Concentrations of seven elements in the intraluminal fluids of the rat seminiferous tubules, rete testis, and epididymis. Biol Reprod 23:981\u2013987","journal-title":"Biol Reprod"},{"key":"9294_CR48","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1152\/physrev.00029.2001","volume":"82","author":"T Jentsch","year":"2002","unstructured":"Jentsch T, Stein V, Weinreich F, Zdebik A (2002) Molecular structure and physiological function of chloride channels. Physiol Rev 82:503","journal-title":"Physiol Rev"},{"key":"9294_CR49","first-page":"116","volume":"15","author":"AL Kierszenbaum","year":"1994","unstructured":"Kierszenbaum AL (1994) Mammalian spermatogenesis in vivo and in vitro: a partnership of spermatogenic and somatic cell lineages. Endocr Rev 15:116\u2013134","journal-title":"Endocr Rev"},{"key":"9294_CR114","doi-asserted-by":"crossref","unstructured":"Ko WH, Chan HC, Chew SB, Wong PDY (1998) Regulated anion secretion in cultured epithelia from sertoli cells of imature rats. J Physiol 512:471\u2013480","DOI":"10.1111\/j.1469-7793.1998.471be.x"},{"key":"9294_CR50","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1530\/jrf.0.0340433","volume":"34","author":"A Koskimies","year":"1973","unstructured":"Koskimies A, Kormano M (1973) The proteins in fluids from the seminiferous tubules and rete testis of the rat. Reproduction 34:433\u2013434","journal-title":"Reproduction"},{"key":"9294_CR51","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1006\/geno.1998.5552","volume":"54","author":"N Koyama","year":"1998","unstructured":"Koyama N, Ishibashi K, Kuwahara M, Inase N, Ichioka M, Sasaki S, Marumo F (1998) Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene. Genomics 54:169\u2013172","journal-title":"Genomics"},{"key":"9294_CR52","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1095\/biolreprod56.3.680","volume":"56","author":"N Lalevee","year":"1997","unstructured":"Lalevee N, Pluciennik F, Joffre M (1997) Voltage-dependent calcium current with properties of T-type current in Sertoli cells from immature rat testis in primary cultures. Biol Reprod 56:680\u2013687","journal-title":"Biol Reprod"},{"key":"9294_CR53","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/aja.1000900202","volume":"90","author":"C Leblond","year":"1952","unstructured":"Leblond C, Clermont Y (1952) Spermiogenesis of rat, mouse, hamster and guinea pig as revealed by the periodic acid-fuchsin sulfurous acid\u201d technique. Am J Anat 90:167\u2013216","journal-title":"Am J Anat"},{"key":"9294_CR54","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1113\/jphysiol.1971.sp009400","volume":"213","author":"N Levine","year":"1971","unstructured":"Levine N, Marsh D (1971) Micropuncture studies of the electrochemical aspects of fluid and electrolyte transport in individual seminiferous tubules, the epididymis and the vas deferens in rats. J Physiol 213:557\u2013570","journal-title":"J Physiol"},{"key":"9294_CR55","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1530\/jrf.0.0430547","volume":"43","author":"N Levine","year":"1975","unstructured":"Levine N, Marsh D (1975) Micropuncture study of the fluid composition of \u201cSertoli cell-only\u201d seminiferous tubules in rats. Reproduction 43:547\u2013549","journal-title":"Reproduction"},{"key":"9294_CR56","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF00768847","volume":"24","author":"J Lingrel","year":"1992","unstructured":"Lingrel J (1992) Na, K-ATPase: isoform structure, function, and expression. J Bioenerg Biomembr 24:263\u2013270","journal-title":"J Bioenerg Biomembr"},{"key":"9294_CR57","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1055\/s-2004-825753","volume":"36","author":"E Loss","year":"2004","unstructured":"Loss E, Jacobsen M, Costa Z, Jacobus A, Borelli F, Wassermann G (2004) Testosterone modulates K+ATP channels in Sertoli cell membrane via the PLC-PIP2 pathway. Horm Metab Res 36:519\u2013525","journal-title":"Horm Metab Res"},{"key":"9294_CR58","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1095\/biolreprod.102.011379","volume":"68","author":"W Lui","year":"2003","unstructured":"Lui W, Lee W, Cheng C (2003a) Sertoli\u2013germ cell adherens junction dynamics in the testis are regulated by RhoB GTPase via the ROCK\/LIMK signaling pathway. Biol Reprod 68:2189","journal-title":"Biol Reprod"},{"key":"9294_CR59","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1095\/biolreprod.102.010371","volume":"68","author":"W Lui","year":"2003","unstructured":"Lui W, Mruk D, Lee W, Cheng C (2003b) Sertoli cell tight junction dynamics: their regulation during spermatogenesis. Biol Reprod 68:1087","journal-title":"Biol Reprod"},{"key":"9294_CR60","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1006\/bbrc.1997.7664","volume":"240","author":"T Ma","year":"1997","unstructured":"Ma T, Yang B, Verkman A (1997) Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver, and heart. Biochem Biophys Res Commun 240:324\u2013328","journal-title":"Biochem Biophys Res Commun"},{"key":"9294_CR61","doi-asserted-by":"crossref","first-page":"G383","DOI":"10.1152\/ajpgi.1999.277.2.G383","volume":"277","author":"J Malakooti","year":"1999","unstructured":"Malakooti J, Dahdal RY, Schmidt L, Layden TJ, Dudeja PK, Ramaswamy K (1999) Molecular cloning, tissue distribution, and functional expression of the human Na+\/H+ exchanger NHE2. Am J Physiol Gastrointest Liver Physiol 277:G383\u2013G390","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"9294_CR62","first-page":"1084","volume":"84","author":"ME Malo","year":"2006","unstructured":"Malo ME, Fliegel L (2006) Physiological role and regulation of the Na+\/H+ exchanger. Can J Physiol Pharmacol 84:1084\u20131095","journal-title":"Can J Physiol Pharmacol"},{"key":"9294_CR63","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jsbmb.2010.01.011","volume":"119","author":"D Menegaz","year":"2010","unstructured":"Menegaz D, Barrientos-Duran A, Kline A, Silva F, Norman A, Mizwicki M, Zanello L (2010) 1\u03b1, 25(OH)2-Vitamin D3 stimulation of secretion via chloride channel activation in Sertoli cells. J Steroid Biochem Mol Biol 119:127\u2013134","journal-title":"J Steroid Biochem Mol Biol"},{"key":"9294_CR64","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.ceca.2006.05.002","volume":"40","author":"B Minke","year":"2006","unstructured":"Minke B (2006) TRP channels and Ca2+ signaling. Cell Calcium 40:261\u2013275","journal-title":"Cell Calcium"},{"key":"9294_CR65","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1210\/er.2003-0022","volume":"25","author":"DD Mruk","year":"2004","unstructured":"Mruk DD, Cheng CY (2004) Sertoli\u2013Sertoli and Sertoli\u2013germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 25:747\u2013806","journal-title":"Endocr Rev"},{"key":"9294_CR66","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1095\/biolreprod33.5.1245","volume":"33","author":"K Muffly","year":"1985","unstructured":"Muffly K, Turner T, Brown M, Hall P (1985) Content of K+ and Na+ in seminiferous tubule and rete testis fluids from Sertoli cell-enriched testes. Biol Reprod 33:1245","journal-title":"Biol Reprod"},{"key":"9294_CR67","doi-asserted-by":"crossref","first-page":"C177","DOI":"10.1152\/ajpcell.1987.253.2.C177","volume":"253","author":"SM O\u2019Grady","year":"1987","unstructured":"O\u2019Grady SM, Palfrey HC, Field M (1987) Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am J Physiol Cell Physiol 253:C177\u2013C192","journal-title":"Am J Physiol Cell Physiol"},{"key":"9294_CR68","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1530\/REP-08-0363","volume":"137","author":"P Oliveira","year":"2009","unstructured":"Oliveira P, Sousa M, Barros A, Moura T, Rebelo da Costa A (2009a) Intracellular pH regulation in human Sertoli cells: role of membrane transporters. Reproduction 137:353","journal-title":"Reproduction"},{"key":"9294_CR69","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00232-008-9139-z","volume":"227","author":"PF Oliveira","year":"2009","unstructured":"Oliveira PF, Sousa M, Barros A, Moura T, Rebelo da Costa A (2009b) Membrane transporters and cytoplasmatic pH regulation on bovine Sertoli cells. J Membr Biol 227:49\u201355","journal-title":"J Membr Biol"},{"key":"9294_CR70","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1172\/JCI8553","volume":"105","author":"AJ Pace","year":"2000","unstructured":"Pace AJ, Lee E, Athirakul K, Coffman TM, O\u2019Brien DA, Koller BH (2000) Failure of spermatogenesis in mouse lines deficient in the Na+-K+-2Cl\u2212 cotransporter. J Clin Invest 105:441\u2013450","journal-title":"J Clin Invest"},{"key":"9294_CR71","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1152\/physiolgenomics.90259.2008","volume":"34","author":"MD Parker","year":"2008","unstructured":"Parker MD, Bouyer P, Daly CM, Boron WF (2008) Cloning and characterization of novel human SLC4A8 gene products encoding Na+-driven Cl\u2212\/HCO3 \u2212 exchanger variants NDCBE-A, -C, and -D. Physiol Genomics 34:265\u2013276","journal-title":"Physiol Genomics"},{"key":"9294_CR72","first-page":"153","volume":"66","author":"C Petersen","year":"2006","unstructured":"Petersen C, Soder O (2006) The Sertoli cell\u2014a hormonal target and \u201csuper\u201dnurse for germ cells that determines testicular size. Horm Res 66:153\u2013161","journal-title":"Horm Res"},{"key":"9294_CR73","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1146\/annurev.physiol.62.1.111","volume":"62","author":"KD Philipson","year":"2000","unstructured":"Philipson KD, Nicoll DA (2000) Sodium\u2013calcium exchange: a molecular perspective. Annu Rev Physiol 62:111\u2013133","journal-title":"Annu Rev Physiol"},{"key":"9294_CR74","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1530\/jrf.0.0630347","volume":"63","author":"LMC Pilsworth","year":"1981","unstructured":"Pilsworth LMC, Hinton BT, Setchell BP (1981) Effects of obstruction of the flow of seminiferous tubule fluid on the germinal epithelium in the rat. J Reprod Fertil 63:347\u2013353","journal-title":"J Reprod Fertil"},{"key":"9294_CR75","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1098\/rstb.2009.0114","volume":"365","author":"G Pointis","year":"2010","unstructured":"Pointis G, Gilleron J, Carette D, Segretain D (2010) Physiological and physiopathological aspects of connexins and communicating gap junctions in spermatogenesis. Philos Trans R Soc B Biol Sci 365:1607","journal-title":"Philos Trans R Soc B Biol Sci"},{"key":"9294_CR76","doi-asserted-by":"crossref","first-page":"11110","DOI":"10.1073\/pnas.88.24.11110","volume":"88","author":"GM Preston","year":"1991","unstructured":"Preston GM, Agre P (1991) Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family. Proc Natl Acad Sci USA 88:11110\u201311114","journal-title":"Proc Natl Acad Sci USA"},{"key":"9294_CR77","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1146\/annurev.ph.55.030193.003141","volume":"55","author":"JR Riordan","year":"1993","unstructured":"Riordan JR (1993) The cystic fibrosis transmembrane conductance regulator. Annu Rev Physiol 55:609\u2013630","journal-title":"Annu Rev Physiol"},{"key":"9294_CR78","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev.physiol.70.113006.100452","volume":"70","author":"A Rojek","year":"2008","unstructured":"Rojek A, Praetorius J, Fr\u00f8kiaer J, Nielsen S, Fenton RA (2008) A current view of the mammalian aquaglyceroporins. Annu Rev Physiol 70:301\u2013327","journal-title":"Annu Rev Physiol"},{"key":"9294_CR79","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00424-003-1180-2","volume":"447","author":"M Romero","year":"2004","unstructured":"Romero M, Fulton C, Boron W (2004) The SLC4 family of HCO3-transporters. Pfl\u00fcgers Arch 447:495\u2013509","journal-title":"Pfl\u00fcgers Arch"},{"key":"9294_CR80","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1210\/en.2006-0969","volume":"148","author":"G Rossi","year":"2007","unstructured":"Rossi G, Gasperi V, Paro R, Barsacchi D, Cecconi S, Maccarrone M (2007) Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase a and aromatase-dependent pathways in mouse primary Sertoli cells. Endocrinology 148:1431\u20131439","journal-title":"Endocrinology"},{"key":"9294_CR81","first-page":"1","volume-title":"The Sertoli cell","author":"L Russell","year":"1993","unstructured":"Russell L (1993) Form, dimensions, and cytology of mammalian Sertoli cells. In: Russell L, Griswold M (eds) The Sertoli cell. Cache River Press, Clearwater, pp 1\u201337"},{"key":"9294_CR82","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1152\/physrev.2000.80.1.211","volume":"80","author":"J Russell","year":"2000","unstructured":"Russell J (2000) Sodium\u2013potassium\u2013chloride cotransport. Physiol Rev 80:211","journal-title":"Physiol Rev"},{"key":"9294_CR83","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1365-2605.1993.tb01156.x","volume":"16","author":"L Russell","year":"2008","unstructured":"Russell L, Ettlin R, Sinha Hikim A, Clegg E (2008) Histological and histopathological evaluation of the testis. Int J Androl 16:83","journal-title":"Int J Androl"},{"key":"9294_CR84","doi-asserted-by":"crossref","first-page":"28849","DOI":"10.1074\/jbc.M300754200","volume":"278","author":"DH Schulze","year":"2003","unstructured":"Schulze DH, Muqhal M, Lederer WJ, Ruknudin AM (2003) Sodium\/calcium exchanger (NCX1) macromolecular complex. J Biol Chem 278:28849\u201328855","journal-title":"J Biol Chem"},{"key":"9294_CR85","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1530\/jrf.0.0230079","volume":"23","author":"B Setchell","year":"1970","unstructured":"Setchell B (1970) The secretion of fluid by the testes of rats, rams and goats with some observations on the effect of age, cryptorchidism and hypophysectomy. Reproduction 23:79\u201385","journal-title":"Reproduction"},{"key":"9294_CR86","volume-title":"The mammalian testis","author":"B Setchell","year":"1978","unstructured":"Setchell B (1978) The mammalian testis. Paul Elek, London"},{"key":"9294_CR87","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/j.1939-4640.1980.tb00003.x","volume":"1","author":"B Setchell","year":"1980","unstructured":"Setchell B (1980) The functional significance of the blood\u2013testis barrier. J Androl 1:3","journal-title":"J Androl"},{"key":"9294_CR88","first-page":"143","volume-title":"Handbook of physiology, vol 5, sect 7","author":"B Setchell","year":"1975","unstructured":"Setchell B, Waites G (1975) The blood\u2013testis barrier. In: Greep RO, Hamilton EW (eds) Handbook of physiology, vol 5, sect 7. American Physiology Society, Washington DC, pp 143\u2013172"},{"key":"9294_CR89","first-page":"1363","volume-title":"The physiology of reproduction","author":"R Sharpe","year":"1994","unstructured":"Sharpe R (1994) Regulation of spermatogenesis. In: Knobil E, Neill JD (eds) The physiology of reproduction, vol 1. Raven Press, New York, pp 1363\u20131434"},{"key":"9294_CR90","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1530\/rep.0.1250769","volume":"125","author":"R Sharpe","year":"2003","unstructured":"Sharpe R, McKinnell C, Kivlin C, Fisher J (2003) Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction 125:769\u2013784","journal-title":"Reproduction"},{"key":"9294_CR91","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/j.1939-4640.1993.tb01659.x","volume":"14","author":"S Shubhada","year":"1993","unstructured":"Shubhada S, Glinz M, Lamb DJ (1993) Sertoli cell secreted growth factor. Cellular origin, paracrine and endocrine regulation of secretion. J Androl 14:99\u2013109","journal-title":"J Androl"},{"key":"9294_CR109","doi-asserted-by":"crossref","unstructured":"Sohara E, Uchida S, Sasaki S (2009) Function of aquaporin-7 in the kidney and the male reproductive system. Handb Exp Pharmacol 190:219\u2013231","DOI":"10.1007\/978-3-540-79885-9_11"},{"key":"9294_CR92","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00232-001-0055-8","volume":"183","author":"M Soleimani","year":"2001","unstructured":"Soleimani M, Burnham C (2001) Na+: HCO3 \u2212 cotransporters (NBC): cloning and characterization. J Membr Biol 183:71\u201384","journal-title":"J Membr Biol"},{"key":"9294_CR93","doi-asserted-by":"crossref","DOI":"10.1016\/S0076-6879(75)39026-5","volume-title":"In vitro techniques for the study of spermatogenesis","author":"A Steinberger","year":"1975","unstructured":"Steinberger A (1975) In vitro techniques for the study of spermatogenesis. Academic Press, New York"},{"key":"9294_CR94","first-page":"169","volume":"11","author":"E Talarico Jr","year":"2005","unstructured":"Talarico E Jr, Kennedy B, Marfurt C, Loeffler K, Mangini N (2005) Expression and immunolocalization of plasma membrane calcium ATPase isoforms in human corneal epithelium. Mol Vis 11:169\u2013178","journal-title":"Mol Vis"},{"key":"9294_CR95","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1679\/aohc.64.159","volume":"64","author":"T Tani","year":"2001","unstructured":"Tani T, Koyama Y, Nihei K, Hatakeyama S, Ohshiro K, Yoshida Y, Yaoita E, Sakai Y, Hatakeyama K, Yamamoto T (2001) Immunolocalization of aquaporin-8 in rat digestive organs and testis. Arch Histol Cytol 64:159\u2013168","journal-title":"Arch Histol Cytol"},{"key":"9294_CR96","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0303-7207(96)03973-1","volume":"126","author":"A Taranta","year":"1997","unstructured":"Taranta A, Morena A, Barbacci E, D\u2019Agostino A (1997) Conotoxin-sensitive Ca2+ voltage-gated channels modulate protein secretion in cultured rat Sertoli cells. Mol Cell Endocrinol 126:117\u2013123","journal-title":"Mol Cell Endocrinol"},{"key":"9294_CR97","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.1210\/jcem.83.12.5304","volume":"83","author":"J Tesarik","year":"1998","unstructured":"Tesarik J, Guido M, Mendoza C, Greco E (1998) Human spermatogenesis in vitro: respective effects of follicle-stimulating hormone and testosterone on meiosis, spermiogenesis, and sertoli cell apoptosis. J Clin Endocrinol Metab 83:4467\u20134473","journal-title":"J Clin Endocrinol Metab"},{"key":"9294_CR98","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF00593663","volume":"318","author":"R Tuck","year":"1970","unstructured":"Tuck R, Setchell B, Waites G, Young J (1970) The composition of fluid collected by micropuncture and catheterization from the seminiferous tubules and rete testis of rats. Pfl\u00fcgers Arch 318:225\u2013243","journal-title":"Pfl\u00fcgers Arch"},{"key":"9294_CR99","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1530\/jrf.0.0720509","volume":"72","author":"T Turner","year":"1984","unstructured":"Turner T (1984) Resorption versus secretion in the rat epididymis. Reproduction 72:509\u2013514","journal-title":"Reproduction"},{"key":"9294_CR100","doi-asserted-by":"crossref","first-page":"F13","DOI":"10.1152\/ajprenal.2000.278.1.F13","volume":"278","author":"AS Verkman","year":"2000","unstructured":"Verkman AS, Mitra AK (2000) Structure and function of aquaporin water channels. Am J Physiol Renal Physiol 278:F13\u2013F28","journal-title":"Am J Physiol Renal Physiol"},{"key":"9294_CR101","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1530\/jrf.0.0210449","volume":"21","author":"JK Voglmayr","year":"1970","unstructured":"Voglmayr JK, Larsen LH, White IG (1970) Metabolism of spermatozoa and composition of fluid collected from the rete testis of living bulls. J Reprod Fertil 21:449\u2013460","journal-title":"J Reprod Fertil"},{"key":"9294_CR102","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1055\/s-2002-35426","volume":"34","author":"E Ledebur Von","year":"2002","unstructured":"Von Ledebur E, Almeida J, Loss E, Wassermann G (2002) Rapid effect of testosterone on rat Sertoli cell membrane potential. Relationship with K+ATP channels. Horm Metab Res 34:550\u2013555","journal-title":"Horm Metab Res"},{"key":"9294_CR103","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1152\/physrev.1982.62.2.624","volume":"62","author":"G Waites","year":"1982","unstructured":"Waites G, Gladwell R (1982) Physiological significance of fluid secretion in the testis and blood\u2013testis barrier. Physiol Rev 62:624\u2013671","journal-title":"Physiol Rev"},{"key":"9294_CR104","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1530\/rep.1.00358","volume":"130","author":"W Walker","year":"2005","unstructured":"Walker W, Cheng J (2005) FSH and testosterone signaling in Sertoli cells. Reproduction 130:15","journal-title":"Reproduction"},{"key":"9294_CR105","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1038\/ncb1072","volume":"5","author":"D Wang","year":"2003","unstructured":"Wang D, King S, Quill T, Doolittle L, Garbers D (2003) A new sperm-specific Na+\/H+ exchanger required for sperm motility and fertility. Nat Cell Biol 5:1117\u20131122","journal-title":"Nat Cell Biol"},{"key":"9294_CR106","doi-asserted-by":"crossref","first-page":"9325","DOI":"10.1073\/pnas.0611296104","volume":"104","author":"D Wang","year":"2007","unstructured":"Wang D, Hu J, Bobulescu IA, Quill TA, McLeroy P, Moe OW, Garbers DL (2007) A sperm-specific Na+\/H+ exchanger (sNHE) is critical for expression and in vivo bicarbonate regulation of the soluble adenylyl cyclase (sAC). Proc Natl Acad Sci USA 104:9325\u20139330","journal-title":"Proc Natl Acad Sci USA"},{"key":"9294_CR107","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.2174\/1381612043383809","volume":"10","author":"G Wassermann","year":"2004","unstructured":"Wassermann G, Loss E (2004) Testosterone action on the Sertoli cell membrane: a KIR6.x channel related effect. Curr Pharm Des 10:2649\u20132656","journal-title":"Curr Pharm Des"},{"key":"9294_CR108","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1440-1681.1997.tb01775.x","volume":"24","author":"E Wintour","year":"1997","unstructured":"Wintour E (1997) Water channels and urea transporters. Clin Exp Pharmacol Physiol 24:1\u20139","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"9294_CR110","doi-asserted-by":"crossref","first-page":"C1161","DOI":"10.1152\/ajpcell.00564.2004","volume":"288","author":"B Yang","year":"2005","unstructured":"Yang B, Song Y, Zhao D, Verkman AS (2005) Phenotype analysis of aquaporin-8 null mice. Am J Physiol Cell Physiol 288:C1161\u2013C1170","journal-title":"Am J Physiol Cell Physiol"},{"key":"9294_CR111","doi-asserted-by":"crossref","first-page":"C417","DOI":"10.1152\/ajpcell.00057.2006","volume":"291","author":"B Yang","year":"2006","unstructured":"Yang B, Zhao D, Solenov E, Verkman AS (2006) Evidence from knockout mice against physiologically significant aquaporin 8-facilitated ammonia transport. Am J Physiol Cell Physiol 291:C417\u2013C423","journal-title":"Am J Physiol Cell Physiol"},{"key":"9294_CR112","doi-asserted-by":"crossref","unstructured":"Yeung CH, Callies C, T\u00fcttelmann F, Kliesch S, Cooper TG (2010) Aquaporins in the human testis and spermatozoa\u2014identification, involvement in sperm volume regulation and clinical relevance. Int J Androl 33(4):629\u2013641","DOI":"10.1111\/j.1365-2605.2009.00998.x"},{"key":"9294_CR113","doi-asserted-by":"crossref","first-page":"14132","DOI":"10.1073\/pnas.241245898","volume":"98","author":"Q Zhou","year":"2001","unstructured":"Zhou Q, Clarke L, Nie R, Carnes K, Lai L-W, Lien Y-HH, Verkman A, Lubahn D, Fisher JS, Katzenellenbogen BS, Hess RA (2001) Estrogen action and male fertility: roles of the sodium\/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function. Proc Natl Acad Sci USA 98:14132\u201314137","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["The Journal of Membrane Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00232-010-9294-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00232-010-9294-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00232-010-9294-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T06:13:17Z","timestamp":1711692797000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00232-010-9294-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":114,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["9294"],"URL":"https:\/\/doi.org\/10.1007\/s00232-010-9294-x","relation":{},"ISSN":["0022-2631","1432-1424"],"issn-type":[{"value":"0022-2631","type":"print"},{"value":"1432-1424","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}