{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:39:20Z","timestamp":1773290360879,"version":"3.50.1"},"reference-count":104,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,12,5]],"date-time":"2014-12-05T00:00:00Z","timestamp":1417737600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Basic Res Cardiol"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s00395-014-0454-5","type":"journal-article","created":{"date-parts":[[2014,12,4]],"date-time":"2014-12-04T06:33:37Z","timestamp":1417674817000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Unraveling the exercise-related proteome signature in heart"],"prefix":"10.1007","volume":"110","author":[{"given":"Rita","family":"Ferreira","sequence":"first","affiliation":[]},{"given":"Daniel","family":"Moreira-Gon\u00e7alves","sequence":"additional","affiliation":[]},{"given":"Ana L\u00facia","family":"Azevedo","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9 Alberto","family":"Duarte","sequence":"additional","affiliation":[]},{"given":"Francisco","family":"Amado","sequence":"additional","affiliation":[]},{"given":"Rui","family":"Vitorino","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2014,12,5]]},"reference":[{"key":"454_CR1","doi-asserted-by":"crossref","first-page":"494572","DOI":"10.1155\/2012\/494572","volume":"2012","author":"C Abdallah","year":"2012","unstructured":"Abdallah C, Dumas-Gaudot E, Renaut J, Sergeant K (2012) Gel-based and gel-free quantitative proteomics approaches at a glance. Int J Plant Genomics 2012:494572. doi: 10.1155\/2012\/494572","journal-title":"Int J Plant Genomics"},{"key":"454_CR2","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0022-2828(85)80027-4","volume":"17","author":"P Anversa","year":"1985","unstructured":"Anversa P, Beghi C, Levicky V, McDonald SL, Kikkawa Y, Olivetti G (1985) Effects of strenuous exercise on the quantitative morphology of left ventricular myocardium in the rat. J Mol Cell Cardiol 17:587\u2013595. doi: 10.1016\/s0022-2828(85)80027-4","journal-title":"J Mol Cell Cardiol"},{"key":"454_CR3","author":"A Ascens\u00e3o","year":"2005","unstructured":"Ascens\u00e3o A, Magalh\u00e3es J, Soares J, Ferreira R, Neuparth M, Marques F, Oliveira P, Duarte J (2005) Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis. Am J Physiol Heart Circ Physiol. doi: 10.1152\/ajpheart.01249.2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"454_CR4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/01.RES.0000069215.36389.8D","volume":"92","author":"CP Baines","year":"2003","unstructured":"Baines CP, Song CX, Zheng YT, Wang GW, Zhang J, Wang OL, Guo Y, Bolli R, Cardwell EM, Ping P (2003) Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria. Circ Res 92:873\u2013880. doi: 10.1161\/01.RES.0000069215.36389.8D","journal-title":"Circ Res"},{"key":"454_CR5","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/j.jprot.2010.06.009","volume":"73","author":"A Bansal","year":"2010","unstructured":"Bansal A, Dai Q, Chiao YA, Hakala KW, Zhang JQ, Weintraub ST, Lindsey ML (2010) Proteomic analysis reveals late exercise effects on cardiac remodeling following myocardial infarction. J Proteomics 73:2041\u20132049. doi: 10.1016\/j.jprot.2010.06.009","journal-title":"J Proteomics"},{"key":"454_CR6","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1136\/hrt.2009.190256","volume":"96","author":"RM Beadle","year":"2010","unstructured":"Beadle RM, Frenneaux M (2010) Modification of myocardial substrate utilisation: a new therapeutic paradigm in cardiovascular disease. Heart 96:824\u2013830. doi: 10.1136\/hrt.2009.190256","journal-title":"Heart"},{"key":"454_CR7","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1055\/s-2007-964899","volume":"28","author":"M Bellafiore","year":"2007","unstructured":"Bellafiore M, Sivverini G, Palumbo D, Macaluso F, Bianco A, Palma A, Farina F (2007) Increased cx43 and angiogenesis in exercised mouse hearts. Int J Sports Med 28:749\u2013755. doi: 10.1055\/s-2007-964899","journal-title":"Int J Sports Med"},{"key":"454_CR8","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1126\/science.1164680","volume":"324","author":"O Bergmann","year":"2009","unstructured":"Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabe-Heider F, Walsh S, Zupicich J, Alkass K, Buchholz BA, Druid H, Jovinge S, Frisen J (2009) Evidence for cardiomyocyte renewal in humans. Science 324:98\u2013102. doi: 10.1126\/science.1164680","journal-title":"Science"},{"key":"454_CR9","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1093\/bioinformatics\/btp101","volume":"25","author":"G Bindea","year":"2009","unstructured":"Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman WH, Pages F, Trajanoski Z, Galon J (2009) ClueGO: a Cytoscape plug-into decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics 25:1091\u20131093. doi: 10.1093\/bioinformatics\/btp101","journal-title":"Bioinformatics"},{"key":"454_CR10","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1002\/pmic.200401356","volume":"6","author":"MO Boluyt","year":"2006","unstructured":"Boluyt MO, Brevick JL, Rogers DS, Randall MJ, Scalia AF, Li ZB (2006) Changes in the rat heart proteome induced by exercise training: increased abundance of heat shock protein hsp20. Proteomics 6:3154\u20133169. doi: 10.1002\/pmic.200401356","journal-title":"Proteomics"},{"key":"454_CR11","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1161\/CIRCULATIONAHA.105.554360","volume":"112","author":"S Boudina","year":"2005","unstructured":"Boudina S, Sena S, O\u2019Neill BT, Tathireddy P, Young ME, Abel ED (2005) Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circ 112:2686\u20132695. doi: 10.1161\/CIRCULATIONAHA.105.554360","journal-title":"Circ"},{"key":"454_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-381264-3.00001-1","volume":"80","author":"IA Brewis","year":"2010","unstructured":"Brewis IA, Brennan P (2010) Proteomics technologies for the global identification and quantification of proteins. Adv Protein Chem Struct Biol 80:1\u201344. doi: 10.1016\/B978-0-12-381264-3.00001-1","journal-title":"Adv Protein Chem Struct Biol"},{"key":"454_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12576-012-0237-4","volume":"63","author":"C Brinkmann","year":"2013","unstructured":"Brinkmann C, Brixius K (2013) Peroxiredoxins and sports: new insights on the antioxidative defense. J Physiol Sci JPS 63:1\u20135. doi: 10.1007\/s12576-012-0237-4","journal-title":"J Physiol Sci JPS"},{"key":"454_CR14","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.regpep.2013.12.005","volume":"188","author":"TL Broderick","year":"2014","unstructured":"Broderick TL, Wang D, Jankowski M, Gutkowska J (2014) Unexpected effects of voluntary exercise training on natriuretic peptide and receptor mRNA expression in the ob\/ob mouse heart. Regul Pept 188:52\u201359. doi: 10.1016\/j.regpep.2013.12.005","journal-title":"Regul Pept"},{"key":"454_CR15","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1113\/jphysiol.2005.095729","volume":"569","author":"DA Brown","year":"2005","unstructured":"Brown DA, Chicco AJ, Jew KN, Johnson MS, Lynch JM, Watson PA, Moore RL (2005) Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat. J Physiol 569:913\u2013924. doi: 10.1113\/jphysiol.2005.095729","journal-title":"J Physiol"},{"key":"454_CR16","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1152\/japplphysiol.00487.2003","volume":"95","author":"DA Brown","year":"2003","unstructured":"Brown DA, Jew KN, Sparagna GC, Musch TI, Moore RL (2003) Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart. J Appl Physiol 95:2510\u20132518. doi: 10.1152\/japplphysiol.00487.2003","journal-title":"J Appl Physiol"},{"key":"454_CR17","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1146\/annurev.pharmtox.45.120403.095802","volume":"45","author":"RD Brown","year":"2005","unstructured":"Brown RD, Ambler SK, Mitchell MD, Long CS (2005) The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 45:657\u2013687. doi: 10.1146\/annurev.pharmtox.45.120403.095802","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"454_CR18","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1152\/physiolgenomics.00185.2004","volume":"21","author":"HPJ Buermans","year":"2005","unstructured":"Buermans HPJ, Redout EM, Schiel AE, Musters RJP, Zuidwijk M, Eijk PP, van Hardeveld C, Kasanmoentalib S, Visser FC, Ylstra B, Simonides WS (2005) Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure. Physiol Genomics 21:314\u2013323. doi: 10.1152\/physiolgenomics.00185.2004","journal-title":"Physiol Genomics"},{"key":"454_CR19","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1074\/mcp.M113.034660","volume":"13","author":"MW Burgess","year":"2014","unstructured":"Burgess MW, Keshishian H, Mani DR, Gillette MA, Carr SA (2014) Simplified and efficient quantification of low-abundance proteins at very high multiplex via targeted mass spectrometry. Mol Cell Proteomics 13:1137\u20131149. doi: 10.1074\/mcp.M113.034660","journal-title":"Mol Cell Proteomics"},{"key":"454_CR20","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/pmic.200800268","volume":"9","author":"JG Burniston","year":"2009","unstructured":"Burniston JG (2009) Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics 9:106\u2013115. doi: 10.1002\/pmic.200800268","journal-title":"Proteomics"},{"key":"454_CR21","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1042\/BC20080108","volume":"101","author":"Y Chen","year":"2009","unstructured":"Chen Y, Cao X (2009) NFAT directly regulates Nk2\u20135 transcription during cardiac cell differentiation. Biol Cell 101:335\u2013349. doi: 10.1042\/BC20080108","journal-title":"Biol Cell"},{"key":"454_CR22","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1477-5956-8-23","volume":"8","author":"F Chevalier","year":"2010","unstructured":"Chevalier F (2010) Highlights on the capacities of \u201cGel-based\u201d proteomics. Proteome Sci 8:23. doi: 10.1186\/1477-5956-8-23","journal-title":"Proteome Sci"},{"key":"454_CR23","doi-asserted-by":"crossref","first-page":"124","DOI":"10.2174\/157340310791162631","volume":"6","author":"S Chugh","year":"2010","unstructured":"Chugh S, Suen C, Gramolini A (2010) Proteomics and mass spectrometry: what have we learned about the heart? Curr Cardiol Rev 6:124\u2013133. doi: 10.2174\/157340310791162631","journal-title":"Curr Cardiol Rev"},{"key":"454_CR24","author":"A Cohen-Solal","year":"2014","unstructured":"Cohen-Solal A, Leclercq C, Deray G, Lasocki S, Zambrowski JJ, Mebazaa A, de Groote P, Damy T, Galinier M (2014) Iron deficiency: an emerging therapeutic target in heart failure. Heart. doi: 10.1136\/heartjnl-2014-305669","journal-title":"Heart"},{"key":"454_CR25","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0735-1097(99)00630-0","volume":"35","author":"JN Cohn","year":"2000","unstructured":"Cohn JN, Ferrari R, Sharpe N (2000) Cardiac remodeling\u2014concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. J Am Coll Cardiol 35:569\u2013582","journal-title":"J Am Coll Cardiol"},{"key":"454_CR26","doi-asserted-by":"crossref","first-page":"e7325","DOI":"10.1371\/journal.pone.0007325","volume":"4","author":"H Das","year":"2009","unstructured":"Das H, George JC, Joseph M, Das M, Abdulhameed N, Blitz A, Khan M, Sakthivel R, Mao HQ, Hoit BD, Kuppusamy P, Pompili VJ (2009) Stem cell therapy with overexpressed VEGF and PDGF genes improves cardiac function in a rat infarct model. PLoS ONE 4:e7325. doi: 10.1371\/journal.pone.0007325","journal-title":"PLoS ONE"},{"key":"454_CR27","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/mic.10.2.113.126","volume":"10","author":"RA Boer de","year":"2003","unstructured":"de Boer RA, Pinto YM, van Veldhuisen DJ (2003) The Imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities. Microcirculation 10:113\u2013126. doi: 10.1038\/sj.mn.7800188","journal-title":"Microcirculation"},{"key":"454_CR28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/978-1-62703-386-2_3","volume":"1005","author":"D Silvestre Di","year":"2013","unstructured":"Di Silvestre D, Brambilla F, Mauri PL (2013) Multidimensional protein identification technology for direct-tissue proteomics of heart. Methods Mol Biol 1005:25\u201338. doi: 10.1007\/978-1-62703-386-2_3","journal-title":"Methods Mol Biol"},{"key":"454_CR29","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/978-1-61779-573-2_20","volume":"854","author":"A Didangelos","year":"2012","unstructured":"Didangelos A, Yin X, Mayr M (2012) Method for protein subfractionation of cardiovascular tissues before DIGE analysis. Methods Mol Biol 854:287\u2013297. doi: 10.1007\/978-1-61779-573-2_20","journal-title":"Methods Mol Biol"},{"key":"454_CR30","first-page":"209","volume":"2","author":"J Diez","year":"2005","unstructured":"Diez J, Gonzalez A, Lopez B, Querejeta R (2005) Mechanisms of disease: pathologic structural remodeling is more than adaptive hypertrophy in hypertensive heart disease. Nature clinical practice. Cardiovasc Med 2:209\u2013216. doi: 10.1038\/ncpcardio0158","journal-title":"Cardiovasc Med"},{"key":"454_CR31","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1136\/heartjnl-2011-300639","volume":"98","author":"GM Ellison","year":"2012","unstructured":"Ellison GM, Waring CD, Vicinanza C, Torella D (2012) Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms. Heart 98:5\u201310. doi: 10.1136\/heartjnl-2011-300639","journal-title":"Heart"},{"key":"454_CR32","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.tcm.2005.05.004","volume":"15","author":"GC Fan","year":"2005","unstructured":"Fan GC, Chu G, Kranias EG (2005) Hsp20 and its cardioprotection. Trends Cardiovasc Med 15:138\u2013141. doi: 10.1016\/j.tcm.2005.05.004","journal-title":"Trends Cardiovasc Med"},{"key":"454_CR33","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.yjmcc.2010.09.013","volume":"51","author":"GC Fan","year":"2011","unstructured":"Fan GC, Kranias EG (2011) Small heat shock protein 20 (HspB6) in cardiac hypertrophy and failure. J Mol Cell Cardiol 51:574\u2013577. doi: 10.1016\/j.yjmcc.2010.09.013","journal-title":"J Mol Cell Cardiol"},{"key":"454_CR34","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1002\/pmic.201000173","volume":"10","author":"R Ferreira","year":"2010","unstructured":"Ferreira R, Vitorino R, Alves RM, Appell HJ, Powers SK, Duarte JA, Amado F (2010) Subsarcolemmal and intermyofibrillar mitochondria proteome differences disclose functional specializations in skeletal muscle. Proteomics 10:3142\u20133154. doi: 10.1002\/pmic.201000173","journal-title":"Proteomics"},{"key":"454_CR35","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1021\/pr4011926","volume":"13","author":"R Ferreira","year":"2014","unstructured":"Ferreira R, Vitorino R, Padrao AI, Espadas G, Mancuso FM, Moreira-Goncalves D, Castro-Sousa G, Henriques-Coelho T, Oliveira PA, Barros AS, Duarte JA, Sabido E, Amado F (2014) Lifelong exercise training modulates cardiac mitochondrial phosphoproteome in rats. J Proteome Res 13:2045\u20132055. doi: 10.1021\/pr4011926","journal-title":"J Proteome Res"},{"key":"454_CR36","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1161\/01.CIR.0000120390.68287.BB","volume":"109","author":"N Frey","year":"2004","unstructured":"Frey N, Katus HA, Olson EN, Hill JA (2004) Hypertrophy of the heart: a new therapeutic target? Circulation 109:1580\u20131589. doi: 10.1161\/01.CIR.0000120390.68287.BB109\/13\/1580","journal-title":"Circulation"},{"issue":"O111","key":"454_CR37","first-page":"016717","volume":"11","author":"LC Gillet","year":"2012","unstructured":"Gillet LC, Navarro P, Tate S, Rost H, Selevsek N, Reiter L, Bonner R, Aebersold R (2012) Targeted data extraction of the MS\/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis. Mol Cell Proteomics 11(O111):016717. doi: 10.1074\/mcp.O111.016717","journal-title":"Mol Cell Proteomics"},{"key":"454_CR38","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1161\/01.cir.0000442015.53336.12","volume":"129","author":"AS Go","year":"2014","unstructured":"Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Judd SE, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Mackey RH, Magid DJ, Marcus GM, Marelli A, Matchar DB, McGuire DK, Mohler ER 3rd, Moy CS, Mussolino ME, Neumar RW, Nichol G, Pandey DK, Paynter NP, Reeves MJ, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Wong ND, Woo D, Turner MB (2014) Executive summary: heart disease and stroke statistics\u20142014 update: a report from the American Heart Association. Circulation 129:399\u2013410. doi: 10.1161\/01.cir.0000442015.53336.12","journal-title":"Circulation"},{"key":"454_CR39","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/cvr\/cvq258","volume":"88","author":"A Gonzalez-Loyola","year":"2010","unstructured":"Gonzalez-Loyola A, Barba I (2010) Mitochondrial metabolism revisited: a route to cardioprotection. Cardiovasc Res 88:209\u2013210. doi: 10.1093\/cvr\/cvq258","journal-title":"Cardiovasc Res"},{"key":"454_CR40","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1002\/pmic.200401031","volume":"4","author":"A Gorg","year":"2004","unstructured":"Gorg A, Weiss W, Dunn MJ (2004) Current two-dimensional electrophoresis technology for proteomics. Proteomics 4:3665\u20133685. doi: 10.1002\/pmic.200401031","journal-title":"Proteomics"},{"key":"454_CR41","author":"ZR Gregorich","year":"2014","unstructured":"Gregorich ZR, Chang YH, Ge Y (2014) Proteomics in heart failure: top-down or bottom-up? Pflug Arch. doi: 10.1007\/s00424-014-1471-9","journal-title":"Pflug Arch"},{"key":"454_CR42","first-page":"117","volume":"25","author":"HJ Gu","year":"2012","unstructured":"Gu HJ, Gao CB, Gong JL, Li XJ, Sun B, Li XN (2012) Comparative proteomic analysis in left ventricular remodeling following myocardial infarction in rats. Biomed Environ Sci 25:117\u2013123. doi: 10.3967\/0895-3988.2012.01.017","journal-title":"Biomed Environ Sci"},{"key":"454_CR43","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1016\/S0140-6736(14)60107-0","volume":"383","author":"G Heusch","year":"2014","unstructured":"Heusch G, Libby P, Gersh B, Yellon D, Bohm M, Lopaschuk G, Opie L (2014) Cardiovascular remodelling in coronary artery disease and heart failure. Lancet 383:1933\u20131943. doi: 10.1016\/S0140-6736(14)60107-0","journal-title":"Lancet"},{"key":"454_CR44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1152\/japplphysiol.00392.2005","volume":"101","author":"M Iemitsu","year":"2006","unstructured":"Iemitsu M, Maeda S, Jesmin S, Otsuki T, Kasuya Y, Miyauchi T (2006) Activation pattern of MAPK signaling in the hearts of trained and untrained rats following a single bout of exercise. J Appl Physiol 101:151\u2013163. doi: 10.1152\/japplphysiol.00392.2005","journal-title":"J Appl Physiol"},{"key":"454_CR45","author":"S Javadov","year":"2014","unstructured":"Javadov S, Jang S, Agostini B (2014) Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectives. Pharmacol Ther. doi: 10.1016\/j.pharmthera.2014.05.013","journal-title":"Pharmacol Ther"},{"key":"454_CR46","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1752-0509-5-60","volume":"5","author":"YF Jin","year":"2011","unstructured":"Jin YF, Han HC, Berger J, Dai Q, Lindsey ML (2011) Combining experimental and mathematical modeling to reveal mechanisms of macrophage-dependent left ventricular remodeling. BMC Syst Biol 5:60. doi: 10.1186\/1752-0509-5-60","journal-title":"BMC Syst Biol"},{"key":"454_CR47","doi-asserted-by":"crossref","first-page":"H144","DOI":"10.1152\/ajpheart.01278.2008","volume":"297","author":"AN Kavazis","year":"2009","unstructured":"Kavazis AN, Alvarez S, Talbert E, Lee Y, Powers SK (2009) Exercise training induces a cardioprotective phenotype and alterations in cardiac subsarcolemmal and intermyofibrillar mitochondrial proteins. Am J Physiol Heart Circ Physiol 297:H144\u2013H152. doi: 10.1152\/ajpheart.01278.2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"454_CR48","doi-asserted-by":"crossref","first-page":"H928","DOI":"10.1152\/ajpheart.01231.2007","volume":"294","author":"AN Kavazis","year":"2008","unstructured":"Kavazis AN, McClung JM, Hood DA, Powers SK (2008) Exercise induces a cardiac mitochondrial phenotype that resists apoptotic stimuli. Am J Physiol Heart Circ Physiol 294:H928\u2013H935. doi: 10.1152\/ajpheart.01231.2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"454_CR49","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1074\/mcp.M900140-MCP200","volume":"8","author":"H Keshishian","year":"2009","unstructured":"Keshishian H, Addona T, Burgess M, Mani DR, Shi X, Kuhn E, Sabatine MS, Gerszten RE, Carr SA (2009) Quantification of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution. Mol Cell Proteomics 8:2339\u20132349. doi: 10.1074\/mcp.M900140-MCP200","journal-title":"Mol Cell Proteomics"},{"key":"454_CR50","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/978-1-60327-310-7_20","volume":"528","author":"KG Kline","year":"2009","unstructured":"Kline KG, Wu CC (2009) MudPIT analysis: application to human heart tissue. Methods Mol Biol 528:281\u2013293. doi: 10.1007\/978-1-60327-310-7_20","journal-title":"Methods Mol Biol"},{"key":"454_CR51","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1054\/j.cardfail.2003.09.001","volume":"9","author":"MA Konstam","year":"2003","unstructured":"Konstam MA, Udelson JE, Anand IS, Cohn JN (2003) Ventricular remodeling in heart failure: a credible surrogate endpoint. J Cardiac Fail 9:350\u2013353","journal-title":"J Cardiac Fail"},{"key":"454_CR52","unstructured":"Kregel KC (2006) Resource book for the design of animal exercise protocols. American Physiological Society"},{"key":"454_CR53","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1128\/MCB.00683-07","volume":"28","author":"AV Kuznetsov","year":"2008","unstructured":"Kuznetsov AV, Smigelskaite J, Doblander C, Janakiraman M, Hermann M, Wurm M, Scheidl SF, Sucher R, Deutschmann A, Troppmair J (2008) Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targets. Mol Biol Cell 28:2304\u20132313. doi: 10.1128\/MCB.00683-07","journal-title":"Mol Biol Cell"},{"key":"454_CR54","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1093\/cvr\/cvs346","volume":"97","author":"SR Langley","year":"2013","unstructured":"Langley SR, Dwyer J, Drozdov I, Yin X, Mayr M (2013) Proteomics: from single molecules to biological pathways. Cardiovasc Res 97:612\u2013622. doi: 10.1093\/cvr\/cvs346","journal-title":"Cardiovasc Res"},{"key":"454_CR55","author":"C Lerchenmuller","year":"2014","unstructured":"Lerchenmuller C, Rosenzweig A (2014) Mechanisms of exercise-induced cardiac growth. Drug Discov Today. doi: 10.1016\/j.drudis.2014.03.010","journal-title":"Drug Discov Today"},{"key":"454_CR56","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1039\/c3mb70422j","volume":"10","author":"C Li","year":"2014","unstructured":"Li C, Qiu Q, Wang Y, Li P, Xiao C, Wang H, Lin Y, Wang W (2014) Time course label-free quantitative analysis of cardiac muscles of rats after myocardial infarction. Mol BioSyst 10:505\u2013513. doi: 10.1039\/c3mb70422j","journal-title":"Mol BioSyst"},{"key":"454_CR57","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1021\/bi400110b","volume":"52","author":"DC Liebler","year":"2013","unstructured":"Liebler DC, Zimmerman LJ (2013) Targeted quantitation of proteins by mass spectrometry. Biochemistry 52:3797\u20133806. doi: 10.1021\/bi400110b","journal-title":"Biochemistry"},{"key":"454_CR58","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1586\/14737159.2013.845089","volume":"13","author":"Y Liu","year":"2013","unstructured":"Liu Y, Huttenhain R, Collins B, Aebersold R (2013) Mass spectrometric protein maps for biomarker discovery and clinical research. Expert Rev Mol Diagn 13:811\u2013825. doi: 10.1586\/14737159.2013.845089","journal-title":"Expert Rev Mol Diagn"},{"key":"454_CR59","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1093\/bioinformatics\/btt138","volume":"29","author":"S Lotia","year":"2013","unstructured":"Lotia S, Montojo J, Dong Y, Bader GD, Pico AR (2013) Cytoscape app store. Bioinformatics 29:1350\u20131351. doi: 10.1093\/bioinformatics\/btt138","journal-title":"Bioinformatics"},{"key":"454_CR60","first-page":"1113","volume":"466","author":"Y Ma","year":"2014","unstructured":"Ma Y, de Castro Bras LE, Toba H, Iyer RP, Hall ME, Winniford MD, Lange RA, Tyagi SC, Lindsey ML (2014) Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling. Pflug Archiv 466:1113\u20131127. doi: 10.1007\/s00424-014-1463-9","journal-title":"Pflug Archiv"},{"key":"454_CR61","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1007\/s12265-012-9398-z","volume":"5","author":"Y Ma","year":"2012","unstructured":"Ma Y, Halade GV, Lindsey ML (2012) Extracellular matrix and fibroblast communication following myocardial infarction. J Cardiovasc Transl Res 5:848\u2013857. doi: 10.1007\/s12265-012-9398-z","journal-title":"J Cardiovasc Transl Res"},{"key":"454_CR62","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.phytochem.2010.11.009","volume":"72","author":"A Matros","year":"2011","unstructured":"Matros A, Kaspar S, Witzel K, Mock HP (2011) Recent progress in liquid chromatography-based separation and label-free quantitative plant proteomics. Phytochemistry 72:963\u2013974. doi: 10.1016\/j.phytochem.2010.11.009","journal-title":"Phytochemistry"},{"key":"454_CR63","author":"DA Megger","year":"2013","unstructured":"Megger DA, Bracht T, Meyer HE, Sitek B (2013) Label-free quantification in clinical proteomics. Biochim Biophys Acta. doi: 10.1016\/j.bbapap.2013.04.001","journal-title":"Biochim Biophys Acta"},{"key":"454_CR64","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1042\/BJ20120705","volume":"447","author":"CK Min","year":"2012","unstructured":"Min CK, Yeom DR, Lee KE, Kwon HK, Kang M, Kim YS, Park ZY, Jeon H, Kim do H (2012) Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca(2)+ transfer from the sarcoplasmic reticulum to the mitochondria in the heart. Biochem J 447:371\u2013379. doi: 10.1042\/BJ20120705","journal-title":"Biochem J"},{"key":"454_CR65","doi-asserted-by":"crossref","first-page":"H1044","DOI":"10.1152\/ajpheart.01008.2010","volume":"300","author":"D Moreira-Gon\u00e7alves","year":"2011","unstructured":"Moreira-Gon\u00e7alves D, Henriques-Coelho T, Fonseca H, Ferreira RM, Amado F, Leite-Moreira A, Duarte JA (2011) Moderate exercise training provides left ventricular tolerance to acute pressure overload. Am J Physiol Heart Circ Physiol 300:H1044\u2013H1052. doi: 10.1152\/ajpheart.01008.2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"454_CR66","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1074\/mcp.R112.025163","volume":"12","author":"S Nahnsen","year":"2013","unstructured":"Nahnsen S, Bielow C, Reinert K, Kohlbacher O (2013) Tools for label-free peptide quantification. Mol Cell Proteomics 12:549\u2013556. doi: 10.1074\/mcp.R112.025163","journal-title":"Mol Cell Proteomics"},{"key":"454_CR67","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.3324\/haematol.2012.072314","volume":"98","author":"H Nam","year":"2013","unstructured":"Nam H, Wang CY, Zhang L, Zhang W, Hojyo S, Fukada T, Knutson MD (2013) ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders. Haematologica 98:1049\u20131057. doi: 10.3324\/haematol.2012.072314","journal-title":"Haematologica"},{"key":"454_CR68","author":"M Ng","year":"2014","unstructured":"Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, Mullany EC, Biryukov S, Abbafati C, Abera SF, Abraham JP, Abu-Rmeileh NM, Achoki T, AlBuhairan FS, Alemu ZA, Alfonso R, Ali MK, Ali R, Guzman NA, Ammar W, Anwari P, Banerjee A, Barquera S, Basu S, Bennett DA, Bhutta Z, Blore J, Cabral N, Nonato IC, Chang JC, Chowdhury R, Courville KJ, Criqui MH, Cundiff DK, Dabhadkar KC, Dandona L, Davis A, Dayama A, Dharmaratne SD, Ding EL, Durrani AM, Esteghamati A, Farzadfar F, Fay DF, Feigin VL, Flaxman A, Forouzanfar MH, Goto A, Green MA, Gupta R, Hafezi-Nejad N, Hankey GJ, Harewood HC, Havmoeller R, Hay S, Hernandez L, Husseini A, Idrisov BT, Ikeda N, Islami F, Jahangir E, Jassal SK, Jee SH, Jeffreys M, Jonas JB, Kabagambe EK, Khalifa SE, Kengne AP, Khader YS, Khang YH, Kim D, Kimokoti RW, Kinge JM, Kokubo Y, Kosen S, Kwan G, Lai T, Leinsalu M, Li Y, Liang X, Liu S, Logroscino G, Lotufo PA, Lu Y, Ma J, Mainoo NK, Mensah GA, Merriman TR, Mokdad AH, Moschandreas J, Naghavi M, Naheed A, Nand D, Narayan KM, Nelson EL, Neuhouser ML, Nisar MI, Ohkubo T, Oti SO, Pedroza A et al (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. doi: 10.1016\/S0140-6736(14)60460-8","journal-title":"Lancet"},{"key":"454_CR69","doi-asserted-by":"crossref","first-page":"e1003472","DOI":"10.1371\/journal.pcbi.1003472","volume":"10","author":"NT Nguyen","year":"2014","unstructured":"Nguyen NT, Zhang X, Wu C, Lange RA, Chilton RJ, Lindsey ML, Jin YF (2014) Integrative computational and experimental approaches to establish a post-myocardial infarction knowledge map. PLoS Comput Biol 10:e1003472. doi: 10.1371\/journal.pcbi.1003472","journal-title":"PLoS Comput Biol"},{"key":"454_CR70","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1016\/S0021-9258(19)41496-8","volume":"250","author":"PH O\u2019Farrell","year":"1975","unstructured":"O\u2019Farrell PH (1975) High resolution two-dimensional electrophoresis of proteins. J Biol Chem 250:4007\u20134021","journal-title":"J Biol Chem"},{"key":"454_CR71","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.bbabio.2011.04.002","volume":"1807","author":"AI Padr\u00e3o","year":"2011","unstructured":"Padr\u00e3o AI, Ferreira RMP, Vitorino R, Alves RMP, Neuparth MJ, Duarte JA, Amado F (2011) OXPHOS susceptibility to oxidative modifications: the role of heart mitochondrial subcellular location. Biochim Biophys Acta 1807:1106\u20131113. doi: 10.1016\/j.bbabio.2011.04.002","journal-title":"Biochim Biophys Acta"},{"key":"454_CR72","doi-asserted-by":"crossref","first-page":"783131","DOI":"10.1155\/2013\/783131","volume":"2013","author":"D Paul","year":"2013","unstructured":"Paul D, Kumar A, Gajbhiye A, Santra MK, Srikanth R (2013) Mass spectrometry-based proteomics in molecular diagnostics: discovery of cancer biomarkers using tissue culture. Biomed Res Int 2013:783131. doi: 10.1155\/2013\/783131","journal-title":"Biomed Res Int"},{"key":"454_CR73","doi-asserted-by":"crossref","first-page":"H1983","DOI":"10.1152\/ajpheart.00784.2010","volume":"300","author":"C Perrino","year":"2011","unstructured":"Perrino C, Gargiulo G, Pironti G, Franzone A, Scudiero L, De Laurentis M, Magliulo F, Ilardi F, Carotenuto G, Schiattarella GG, Esposito G (2011) Cardiovascular effects of treadmill exercise in physiological and pathological preclinical settings. Am J Physiol Heart Circ Physiol 300:H1983\u2013H1989. doi: 10.1152\/ajpheart.00784.2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"454_CR74","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1002\/jcp.24231","volume":"228","author":"BA Petriz","year":"2013","unstructured":"Petriz BA, Cunha VN, Villeth GR, Mehta A, Rocha LA, Silva ON, Almeida JA, Morais PK, Simoes HG, Franco OL (2013) Effects of acute exercise over heart proteome from monogenic obese (ob\/ob) mice. J Cell Physiol 228:824\u2013834. doi: 10.1002\/jcp.24231","journal-title":"J Cell Physiol"},{"key":"454_CR75","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1477-5956-11-17","volume":"11","author":"SR Piersma","year":"2013","unstructured":"Piersma SR, Warmoes MO, de Wit M, de Reus I, Knol JC, Jimenez CR (2013) Whole gel processing procedure for GeLC\u2013MS\/MS based proteomics. Proteome Sci 11:17. doi: 10.1186\/1477-5956-11-17","journal-title":"Proteome Sci"},{"key":"454_CR76","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.yjmcc.2012.11.010","volume":"54","author":"S Pons","year":"2013","unstructured":"Pons S, Martin V, Portal L, Zini R, Morin D, Berdeaux A, Ghaleh B (2013) Regular treadmill exercise restores cardioprotective signaling pathways in obese mice independently from improvement in associated co-morbidities. J Mol Cell Cardiol 54:82\u201389. doi: 10.1016\/j.yjmcc.2012.11.010","journal-title":"J Mol Cell Cardiol"},{"key":"454_CR77","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.freeradbiomed.2007.02.006","volume":"44","author":"SK Powers","year":"2008","unstructured":"Powers SK, Quindry JC, Kavazis AN (2008) Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury. Free Radic Biol Med 44:193\u2013201. doi: 10.1016\/j.freeradbiomed.2007.02.006","journal-title":"Free Radic Biol Med"},{"key":"454_CR78","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3109\/10715762.2013.825371","volume":"48","author":"SK Powers","year":"2014","unstructured":"Powers SK, Sollanek KJ, Wiggs MP, Demirel HA, Smuder AJ (2014) Exercise-induced improvements in myocardial antioxidant capacity: the antioxidant players and cardioprotection. Free Radic Res 48:43\u201351. doi: 10.3109\/10715762.2013.825371","journal-title":"Free Radic Res"},{"key":"454_CR79","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1016\/j.jprot.2010.05.016","volume":"73","author":"T Rabilloud","year":"2010","unstructured":"Rabilloud T, Chevallet M, Luche S, Lelong C (2010) Two-dimensional gel electrophoresis in proteomics: past, present and future. J Proteomics 73:2064\u20132077. doi: 10.1016\/j.jprot.2010.05.016","journal-title":"J Proteomics"},{"key":"454_CR80","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1161\/CIRCULATIONAHA.113.001971","volume":"128","author":"MJ Ranek","year":"2013","unstructured":"Ranek MJ, Terpstra EJ, Li J, Kass DA, Wang X (2013) Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins. Circulation 128:365\u2013376. doi: 10.1161\/CIRCULATIONAHA.113.001971","journal-title":"Circulation"},{"key":"454_CR81","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.ijcard.2012.04.045","volume":"167","author":"R Ravichandran","year":"2013","unstructured":"Ravichandran R, Venugopal JR, Sundarrajan S, Mukherjee S, Sridhar R, Ramakrishna S (2013) Expression of cardiac proteins in neonatal cardiomyocytes on PGS\/fibrinogen core\/shell substrate for Cardiac tissue engineering. Int J Cardiol 167:1461\u20131468. doi: 10.1016\/j.ijcard.2012.04.045","journal-title":"Int J Cardiol"},{"key":"454_CR82","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1472-6793-12-11","volume":"12","author":"LA Rocha","year":"2012","unstructured":"Rocha LA, Petriz BA, Borges DH, Oliveira RJ, de Andrade RV, Domont GB, Pereira RW, Franco OL (2012) High molecular mass proteomics analyses of left ventricle from rats subjected to differential swimming training. BMC physiol 12:11. doi: 10.1186\/1472-6793-12-11","journal-title":"BMC physiol"},{"key":"454_CR83","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s00395-013-0332-6","volume":"108","author":"SR Roof","year":"2013","unstructured":"Roof SR, Tang L, Ostler JE, Periasamy M, Gyorke S, Billman GE, Ziolo MT (2013) Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise. Basic Res Cardiol 108:332. doi: 10.1007\/s00395-013-0332-6","journal-title":"Basic Res Cardiol"},{"key":"454_CR84","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1152\/physrev.00054.2009","volume":"90","author":"BA Rose","year":"2010","unstructured":"Rose BA, Force T, Wang Y (2010) Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 90:1507\u20131546. doi: 10.1152\/physrev.00054.2009","journal-title":"Physiol Rev"},{"key":"454_CR85","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1126\/science.1228951","volume":"338","author":"A Rosenzweig","year":"2012","unstructured":"Rosenzweig A (2012) Medicine. Cardiac regeneration. Science 338:1549\u20131550. doi: 10.1126\/science.1228951","journal-title":"Science"},{"key":"454_CR86","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11010-013-1662-2","volume":"380","author":"KA Salem","year":"2013","unstructured":"Salem KA, Qureshi MA, Sydorenko V, Parekh K, Jayaprakash P, Iqbal T, Singh J, Oz M, Adrian TE, Howarth FC (2013) Effects of exercise training on excitation-contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats. Mol Cell Biochem 380:83\u201396. doi: 10.1007\/s11010-013-1662-2","journal-title":"Mol Cell Biochem"},{"key":"454_CR87","author":"A Silva","year":"2013","unstructured":"Silva A, Vitorino R, Domingues MR, Spickett CM, Domingues P (2013) Post-translational modifications and mass spectrometry detection. Free Radic Biol Med. doi: 10.1016\/j.freeradbiomed.2013.08.184","journal-title":"Free Radic Biol Med"},{"key":"454_CR88","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.cbd.2007.11.001","volume":"3","author":"B Sun","year":"2008","unstructured":"Sun B, Wang JH, Lv YY, Zhu SS, Yang J, Ma JZ (2008) Proteomic adaptation to chronic high intensity swimming training in the rat heart. Comp Biochem Physiol Part D Genomics Proteomics 3:108\u2013117. doi: 10.1016\/j.cbd.2007.11.001","journal-title":"Comp Biochem Physiol Part D Genomics Proteomics"},{"key":"454_CR89","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.yjmcc.2012.06.001","volume":"53","author":"Z Sun","year":"2012","unstructured":"Sun Z, Hamilton KL, Reardon KF (2012) Phosphoproteomics and molecular cardiology: techniques, applications and challenges. J Mol Cell Cardiol 53:354\u2013368. doi: 10.1016\/j.yjmcc.2012.06.001","journal-title":"J Mol Cell Cardiol"},{"key":"454_CR90","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1038\/nprot.2006.256","volume":"1","author":"NS Tannu","year":"2006","unstructured":"Tannu NS, Hemby SE (2006) Two-dimensional fluorescence difference gel electrophoresis for comparative proteomics profiling. Nat Protoc 1:1732\u20131742. doi: 10.1038\/nprot.2006.256","journal-title":"Nat Protoc"},{"key":"454_CR91","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1172\/JCI28884","volume":"116","author":"JC Tardiff","year":"2006","unstructured":"Tardiff JC (2006) Cardiac hypertrophy: stressing out the heart. J Clin Invest 116:1467\u20131470. doi: 10.1172\/JCI28884","journal-title":"J Clin Invest"},{"key":"454_CR92","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/1479-7364-4-5-353","volume":"4","author":"S Thomas","year":"2010","unstructured":"Thomas S, Bonchev D (2010) A survey of current software for network analysis in molecular biology. Hum Genomics 4:353\u2013360","journal-title":"Hum Genomics"},{"key":"454_CR93","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.yjmcc.2012.03.015","volume":"53","author":"ND Ullrich","year":"2012","unstructured":"Ullrich ND, Valdivia HH, Niggli E (2012) PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity. J Mol Cell Cardiol 53:33\u201342. doi: 10.1016\/j.yjmcc.2012.03.015","journal-title":"J Mol Cell Cardiol"},{"key":"454_CR94","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-94-007-5896-4_1","volume":"990","author":"SK Riper Van","year":"2013","unstructured":"Van Riper SK, de Jong EP, Carlis JV, Griffin TJ (2013) Mass spectrometry-based proteomics: basic principles and emerging technologies and directions. Adv Exp Med Biol 990:1\u201335. doi: 10.1007\/978-94-007-5896-4_1","journal-title":"Adv Exp Med Biol"},{"key":"454_CR95","doi-asserted-by":"crossref","first-page":"E519","DOI":"10.1152\/ajpendo.00617.2013","volume":"306","author":"R Vettor","year":"2014","unstructured":"Vettor R, Valerio A, Ragni M, Trevellin E, Granzotto M, Olivieri M, Tedesco L, Ruocco C, Fossati A, Fabris R, Serra R, Carruba MO, Nisoli E (2014) Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism. Am J Physiol Endocrinol Metab 306:E519\u2013E528. doi: 10.1152\/ajpendo.00617.2013","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"454_CR96","author":"CD Waring","year":"2012","unstructured":"Waring CD, Vicinanza C, Papalamprou A, Smith AJ, Purushothaman S, Goldspink DF, Nadal-Ginard B, Torella D, Ellison GM (2012) The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation. Eur Heart J. doi: 10.1093\/eurheartj\/ehs338","journal-title":"Eur Heart J"},{"key":"454_CR97","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/BF00805566","volume":"92","author":"P Whittaker","year":"1997","unstructured":"Whittaker P (1997) Collagen and ventricular remodeling after acute myocardial infarction: concepts and hypotheses. Basic Res Cardiol 92:79\u201381","journal-title":"Basic Res Cardiol"},{"key":"454_CR98","doi-asserted-by":"crossref","first-page":"H1301","DOI":"10.1152\/ajpheart.2001.280.3.H1301","volume":"280","author":"U Wisloff","year":"2001","unstructured":"Wisloff U, Helgerud J, Kemi OJ, Ellingsen O (2001) Intensity-controlled treadmill running in rats: VO(2 max) and cardiac hypertrophy. Am J Physiol Heart Circ Physiol 280:H1301\u2013H1310","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"454_CR99","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2012.04.010","volume":"731","author":"Q Wu","year":"2012","unstructured":"Wu Q, Yuan H, Zhang L, Zhang Y (2012) Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: from qualitative to quantitative analysis\u2014a review. Anal Chim Acta 731:1\u201310. doi: 10.1016\/j.aca.2012.04.010","journal-title":"Anal Chim Acta"},{"key":"454_CR100","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/eurjhf\/hfq196","volume":"13","author":"F Xiang","year":"2011","unstructured":"Xiang F, Shi Z, Guo X, Qiu Z, Chen X, Huang F, Sha J (2011) Proteomic analysis of myocardial tissue from the border zone during early stage post-infarct remodelling in rats. Eur J Heart Fail 13:254\u2013263. doi: 10.1093\/eurjhf\/hfq196","journal-title":"Eur J Heart Fail"},{"key":"454_CR101","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1113\/expphysiol.2010.054221","volume":"95","author":"X Xu","year":"2010","unstructured":"Xu X, Zhao W, Wan W, Ji LL, Powers AS, Erikson JM, Zhang JQ (2010) Exercise training combined with angiotensin II receptor blockade reduces oxidative stress after myocardial infarction in rats. Exp Physiol 95:1008\u20131015. doi: 10.1113\/expphysiol.2010.054221","journal-title":"Exp Physiol"},{"key":"454_CR102","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/protein\/gzq094","volume":"24","author":"Y Xue","year":"2011","unstructured":"Xue Y, Liu Z, Cao J, Ma Q, Gao X, Wang Q, Jin C, Zhou Y, Wen L, Ren J (2011) GPS 2.1: enhanced prediction of kinase-specific phosphorylation sites with an algorithm of motif length selection. Protein Eng Des Sel 24:255\u2013260. doi: 10.1093\/protein\/gzq094","journal-title":"Protein Eng Des Sel"},{"key":"454_CR103","first-page":"276","volume":"14","author":"A Yabluchanskiy","year":"2013","unstructured":"Yabluchanskiy A, Li Y, Chilton RJ, Lindsey ML (2013) Matrix metalloproteinases: drug targets for myocardial infarction. Curr Drug Targets 14:276\u2013286","journal-title":"Curr Drug Targets"},{"key":"454_CR104","author":"JR Yates","year":"2013","unstructured":"Yates JR (2013) The revolution and evolution of shotgun proteomics for large-scale proteome analysis. J Am Chem Soc. doi: 10.1021\/ja3094313","journal-title":"J Am Chem Soc"}],"container-title":["Basic Research in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00395-014-0454-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00395-014-0454-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00395-014-0454-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T21:24:03Z","timestamp":1650749043000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00395-014-0454-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,5]]},"references-count":104,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["454"],"URL":"https:\/\/doi.org\/10.1007\/s00395-014-0454-5","relation":{},"ISSN":["0300-8428","1435-1803"],"issn-type":[{"value":"0300-8428","type":"print"},{"value":"1435-1803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,5]]},"article-number":"454"}}