{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:39:05Z","timestamp":1771623545728,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1007\/s00417-021-05076-5","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T10:06:58Z","timestamp":1611569218000},"page":"1731-1740","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Epiretinal membrane vitrectomy: outcomes with or without cataract surgery and a novel prognostic factor for cystoid macular edema"],"prefix":"10.1007","volume":"259","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5607-3212","authenticated-orcid":false,"given":"Nisa","family":"Silva","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8577-5128","authenticated-orcid":false,"given":"Andr\u00e9","family":"Ferreira","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6487-7950","authenticated-orcid":false,"given":"Jo\u00e3o Heitor","family":"Marques","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4607-8586","authenticated-orcid":false,"given":"Nat\u00e1lia","family":"Ferreira","sequence":"additional","affiliation":[]},{"given":"Nuno","family":"Correia","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5673-1561","authenticated-orcid":false,"given":"Bernardete","family":"Pessoa","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8642-7010","authenticated-orcid":false,"given":"Jo\u00e3o Melo","family":"Beir\u00e3o","sequence":"additional","affiliation":[]},{"given":"Ferenc","family":"Kuhn","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9148-2786","authenticated-orcid":false,"given":"Angelina","family":"Meireles","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"issue":"1","key":"5076_CR1","first-page":"36","volume":"173","author":"R Machemer","year":"1978","unstructured":"Machemer R (1978) The surgical removal of epiretinal macular membranes (macular puckers) (author\u2019s transl). Klin Monatsbl Augenheilkd 173(1):36\u201342","journal-title":"Klin Monatsbl Augenheilkd"},{"issue":"4","key":"5076_CR2","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/s0002-9394(14)72377-3","volume":"111","author":"GM Cherfan","year":"1991","unstructured":"Cherfan GM, Michels RG, de Bustros S, Enger C, Glaser BM (1991) Nuclear sclerotic cataract after vitrectomy for idiopathic epiretinal membranes causing macular pucker. Am J Ophthalmol 111(4):434\u2013438. https:\/\/doi.org\/10.1016\/s0002-9394(14)72377-3","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"5076_CR3","first-page":"1","volume":"1","author":"H Dermer","year":"2019","unstructured":"Dermer H, Hussain RM, Lin J, Vanner EA, Haddock LJ, Gregori NZ (2019) Combined phacovitrectomy versus sequential approach in eyes with epiretinal membrane and cataract. OSP J Ophthal 1(1):1\u20139","journal-title":"OSP J Ophthal"},{"issue":"3","key":"5076_CR4","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/aos.13572","volume":"96","author":"H Hamoudi","year":"2018","unstructured":"Hamoudi H, Correll Christensen U, La Cour M (2018) Epiretinal membrane surgery: an analysis of 2-step sequential- or combined phacovitrectomy surgery on refraction and macular anatomy in a prospective trial. Acta Ophthalmol 96(3):243\u2013250. https:\/\/doi.org\/10.1111\/aos.13572","journal-title":"Acta Ophthalmol"},{"issue":"4","key":"5076_CR5","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1177\/112067210701700419","volume":"17","author":"Z Szijarto","year":"2007","unstructured":"Szijarto Z, Haszonits B, Biro Z, Kovacs B (2007) Phacoemulsification on previously vitrectomized eyes: results of a 10-year period. Eur J Ophthalmol 17(4):601\u2013604. https:\/\/doi.org\/10.1177\/112067210701700419","journal-title":"Eur J Ophthalmol"},{"issue":"6","key":"5076_CR6","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1097\/IAE.0000000000000061","volume":"34","author":"MI Seider","year":"2014","unstructured":"Seider MI, Michael Lahey J, Fellenbaum PS (2014) Cost of phacovitrectomy versus vitrectomy and sequential phacoemulsification. Retina 34(6):1112\u20131115. https:\/\/doi.org\/10.1097\/IAE.0000000000000061","journal-title":"Retina"},{"issue":"6","key":"5076_CR7","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1016\/j.jcrs.2007.01.047","volume":"33","author":"DH Steel","year":"2007","unstructured":"Steel DH (2007) Phacovitrectomy: expanding indications. J Cataract Refract Surg 33(6):933\u2013936","journal-title":"J Cataract Refract Surg"},{"issue":"9","key":"5076_CR8","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1097\/IAE.0000000000002034","volume":"38","author":"MAP Fajgenbaum","year":"2018","unstructured":"Fajgenbaum MAP, Neffendorf JE, Wong RS, Laidlaw DAH, Williamson TH (2018) Intraoperative and postoperative complications in phacovitrectomy for epiretinal membrane and macular hole: a clinical audit of 1,000 consecutive eyes. Retina 38(9):1865\u20131872. https:\/\/doi.org\/10.1097\/IAE.0000000000002034","journal-title":"Retina"},{"issue":"5","key":"5076_CR9","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1016\/j.jcrs.2008.12.032","volume":"35","author":"SP Park","year":"2009","unstructured":"Park SP, Ahn JK, Lee GH (2009) Morphologic changes in the anterior segment after phacovitrectomy for proliferative diabetic retinopathy. J Cataract Refract Surg 35(5):868\u2013873. https:\/\/doi.org\/10.1016\/j.jcrs.2008.12.032","journal-title":"J Cataract Refract Surg"},{"issue":"1","key":"5076_CR10","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/s00417-008-0926-0","volume":"247","author":"C Lange","year":"2009","unstructured":"Lange C, Feltgen N, Junker B, Schulze-Bonsel K, Bach M (2009) Resolving the clinical acuity categories \u201chand motion\u201d and \u201ccounting fingers\u201d using the Freiburg Visual Acuity Test (FrACT). Graefes Arch Clin Exp Ophthalmol 247(1):137\u2013142. https:\/\/doi.org\/10.1007\/s00417-008-0926-0","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"4","key":"5076_CR11","doi-asserted-by":"publisher","first-page":"388","DOI":"10.3928\/1081-597X-19970701-16","volume":"13","author":"JT Holladay","year":"1997","unstructured":"Holladay JT (1997) Proper method for calculating average visual acuity. J Refract Surg 13(4):388\u2013391","journal-title":"J Refract Surg"},{"issue":"4","key":"5076_CR12","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.jcrs.2018.01.029","volume":"44","author":"LHP Wielders","year":"2018","unstructured":"Wielders LHP, Schouten J, Winkens B, van den Biggelaar F, Veldhuizen CA, Findl O, Murta JCN, Goslings WRO, Tassignon MJ, Joosse MV, Henry YP, Rulo AHF, Guell JL, Amon M, Kohnen T, Nuijts R, Group EPS (2018) European multicenter trial of the prevention of cystoid macular edema after cataract surgery in nondiabetics: ESCRS PREMED study report 1. J Cataract Refract Surg 44(4):429\u2013439. https:\/\/doi.org\/10.1016\/j.jcrs.2018.01.029","journal-title":"J Cataract Refract Surg"},{"key":"5076_CR13","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.ajo.2016.12.006","volume":"175","author":"A Govetto","year":"2017","unstructured":"Govetto A, Lalane RA 3rd, Sarraf D, Figueroa MS, Hubschman JP (2017) Insights into epiretinal membranes: presence of ectopic inner foveal layers and a new optical coherence tomography staging scheme. Am J Ophthalmol 175:99\u2013113. https:\/\/doi.org\/10.1016\/j.ajo.2016.12.006","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"5076_CR14","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.ophtha.2011.08.026","volume":"119","author":"K Tsunoda","year":"2012","unstructured":"Tsunoda K, Watanabe K, Akiyama K, Usui T, Noda T (2012) Highly reflective foveal region in optical coherence tomography in eyes with vitreomacular traction or epiretinal membrane. Ophthalmology 119(3):581\u2013587. https:\/\/doi.org\/10.1016\/j.ophtha.2011.08.026","journal-title":"Ophthalmology"},{"issue":"2","key":"5076_CR15","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1097\/iae.0b013e3181b8628e","volume":"30","author":"KA Warren","year":"2010","unstructured":"Warren KA, Bahrani H, Fox JE (2010) NSAIDs in combination therapy for the treatment of chronic pseudophakic cystoid macular edema. Retina 30(2):260\u2013266. https:\/\/doi.org\/10.1097\/iae.0b013e3181b8628e","journal-title":"Retina"},{"issue":"4","key":"5076_CR16","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1016\/j.ajo.2008.04.036","volume":"146","author":"JR Wittpenn","year":"2008","unstructured":"Wittpenn JR, Silverstein S, Heier J, Kenyon KR, Hunkeler JD, Earl M, Acular LSCMESG (2008) A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients. Am J Ophthalmol 146(4):554\u2013560. https:\/\/doi.org\/10.1016\/j.ajo.2008.04.036","journal-title":"Am J Ophthalmol"},{"key":"5076_CR17","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.2147\/OPTH.S31902","volume":"6","author":"R Singh","year":"2012","unstructured":"Singh R, Alpern L, Jaffe GJ, Lehmann RP, Lim J, Reiser HJ, Sall K, Walters T, Sager D (2012) Evaluation of nepafenac in prevention of macular edema following cataract surgery in patients with diabetic retinopathy. Clin Ophthalmol 6:1259\u20131269. https:\/\/doi.org\/10.2147\/OPTH.S31902","journal-title":"Clin Ophthalmol"},{"issue":"1","key":"5076_CR18","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1097\/icu.0b013e3283199162","volume":"20","author":"SJ Kim","year":"2009","unstructured":"Kim SJ, Bressler NM (2009) Optical coherence tomography and cataract surgery. Curr Opin Ophthalmol 20(1):46\u201351. https:\/\/doi.org\/10.1097\/icu.0b013e3283199162","journal-title":"Curr Opin Ophthalmol"},{"issue":"6","key":"5076_CR19","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/j.ajo.2010.06.025","volume":"150","author":"A Giani","year":"2010","unstructured":"Giani A, Cigada M, Choudhry N, Deiro AP, Oldani M, Pellegrini M, Invernizzi A, Duca P, Miller JW, Staurenghi G (2010) Reproducibility of retinal thickness measurements on normal and pathologic eyes by different optical coherence tomography instruments. Am J Ophthalmol 150(6):815\u2013824. https:\/\/doi.org\/10.1016\/j.ajo.2010.06.025","journal-title":"Am J Ophthalmol"},{"key":"5076_CR20","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.2147\/CIA.S111761","volume":"11","author":"A Grzybowski","year":"2016","unstructured":"Grzybowski A, Sikorski BL, Ascaso FJ, Huerva V (2016) Pseudophakic cystoid macular edema: update 2016. Clin Interv Aging 11:1221\u20131229. https:\/\/doi.org\/10.2147\/CIA.S111761","journal-title":"Clin Interv Aging"},{"issue":"2","key":"5076_CR21","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.ajo.2009.09.011","volume":"149","author":"B Dugas","year":"2010","unstructured":"Dugas B, Ouled-Moussa R, Lafontaine PO, Guillaubey A, Berrod JP, Hubert I, Bron AM, Creuzot-Garcher CP (2010) Idiopathic epiretinal macular membrane and cataract extraction: combined versus consecutive surgery. Am J Ophthalmol 149(2):302\u2013306. https:\/\/doi.org\/10.1016\/j.ajo.2009.09.011","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"5076_CR22","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s00417-014-2655-x","volume":"253","author":"R Frisina","year":"2015","unstructured":"Frisina R, Pinackatt SJ, Sartore M, Monfardini A, Baldi A, Cesana BM, Semeraro F, Bratu A, Parolini B (2015) Cystoid macular edema after pars plana vitrectomy for idiopathic epiretinal membrane. Graefes Arch Clin Exp Ophthalmol 253(1):47\u201356. https:\/\/doi.org\/10.1007\/s00417-014-2655-x","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"5076_CR23","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1001\/jamaophthalmol.2017.5849","volume":"136","author":"JS Hardin","year":"2018","unstructured":"Hardin JS, Gauldin DW, Soliman MK, Chu CJ, Yang YC, Sallam AB (2018) Cataract surgery outcomes in eyes with primary epiretinal membrane. JAMA Ophthalmol 136(2):148\u2013154. https:\/\/doi.org\/10.1001\/jamaophthalmol.2017.5849","journal-title":"JAMA Ophthalmol"},{"key":"5076_CR24","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.2147\/OPTH.S68661","volume":"8","author":"H Feng","year":"2014","unstructured":"Feng H, Adelman RA (2014) Cataract formation following vitreoretinal procedures. Clin Ophthalmol 8:1957\u20131965. https:\/\/doi.org\/10.2147\/OPTH.S68661","journal-title":"Clin Ophthalmol"},{"issue":"9","key":"5076_CR25","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1097\/IAE.0000000000000558","volume":"35","author":"G Reilly","year":"2015","unstructured":"Reilly G, Melamud A, Lipscomb P, Toussaint B (2015) Surgical outcomes in patients with macular pucker and good preoperative visual acuity after vitrectomy with membrane peeling. Retina 35(9):1817\u20131821. https:\/\/doi.org\/10.1097\/IAE.0000000000000558","journal-title":"Retina"},{"key":"5076_CR26","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1038\/s41433-018-0153-9","volume":"32","author":"S Doguizi","year":"2018","unstructured":"Doguizi S, Sekeroglu MA, Ozkoyuncu D, Omay AE, Yilmazbas P (2018) Clinical significance of ectopic inner foveal layers in patients with idiopathic epiretinal membranes. Eye (Lond) 32:1652\u20131660. https:\/\/doi.org\/10.1038\/s41433-018-0153-9","journal-title":"Eye (Lond)"},{"issue":"1","key":"5076_CR27","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000502748","volume":"243","author":"JY Kim","year":"2020","unstructured":"Kim JY, Kim DY, Kim KT, Song J, Chae JB, Kim JG (2020) Visual prognostic factors of epiretinal membrane surgery in patients with pseudophakia. Ophthalmologica 243(1):43\u201350. https:\/\/doi.org\/10.1159\/000502748","journal-title":"Ophthalmologica"},{"issue":"2","key":"5076_CR28","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1001\/jamaophthalmol.2013.686","volume":"131","author":"K Watanabe","year":"2013","unstructured":"Watanabe K, Tsunoda K, Mizuno Y, Akiyama K, Noda T (2013) Outer retinal morphology and visual function in patients with idiopathic epiretinal membrane. JAMA Ophthalmol 131(2):172\u2013177. https:\/\/doi.org\/10.1001\/jamaophthalmol.2013.686","journal-title":"JAMA Ophthalmol"},{"issue":"1","key":"5076_CR29","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.ajo.2011.06.021","volume":"153","author":"JH Kim","year":"2012","unstructured":"Kim JH, Kim YM, Chung EJ, Lee SY, Koh HJ (2012) Structural and functional predictors of visual outcome of epiretinal membrane surgery. Am J Ophthalmol 153(1):103\u2013110 e101. https:\/\/doi.org\/10.1016\/j.ajo.2011.06.021","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"5076_CR30","doi-asserted-by":"publisher","first-page":"698.e1","DOI":"10.1016\/j.ajo.2011.09.011","volume":"153","author":"M Shimozono","year":"2012","unstructured":"Shimozono M, Oishi A, Hata M, Matsuki T, Ito S, Ishida K, Kurimoto Y (2012) The significance of cone outer segment tips as a prognostic factor in epiretinal membrane surgery. Am J Ophthalmol 153(4):698.e1\u2013704.e1. https:\/\/doi.org\/10.1016\/j.ajo.2011.09.011","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"5076_CR31","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/j.ajo.2010.06.006","volume":"150","author":"M Inoue","year":"2010","unstructured":"Inoue M, Morita S, Watanabe Y, Kaneko T, Yamane S, Kobayashi S, Arakawa A, Kadonosono K (2010) Inner segment\/outer segment junction assessed by spectral-domain optical coherence tomography in patients with idiopathic epiretinal membrane. Am J Ophthalmol 150(6):834\u2013839. https:\/\/doi.org\/10.1016\/j.ajo.2010.06.006","journal-title":"Am J Ophthalmol"},{"key":"5076_CR32","doi-asserted-by":"publisher","unstructured":"Stevenson W, Prospero Ponce CM, Agarwal DR, Gelman R, Christoforidis JB (2016) Epiretinal membrane: optical coherence tomography-based diagnosis and classification. Clin Ophthalmol 10:527\u2013534. https:\/\/doi.org\/10.2147\/OPTH.S97722","DOI":"10.2147\/OPTH.S97722"},{"issue":"1","key":"5076_CR33","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1177\/112067210601600110","volume":"16","author":"A Pardo-Munoz","year":"2006","unstructured":"Pardo-Munoz A, Muriel-Herrero A, Abraira V, Muriel A, Munoz-Negrete FJ, Murube J (2006) Phacoemulsification in previously vitrectomized patients: an analysis of the surgical results in 100 eyes as well as the factors contributing to the cataract formation. Eur J Ophthalmol 16(1):52\u201359. https:\/\/doi.org\/10.1177\/112067210601600110","journal-title":"Eur J Ophthalmol"},{"issue":"10","key":"5076_CR34","doi-asserted-by":"publisher","first-page":"2026","DOI":"10.1097\/IAE.0b013e3182561fab","volume":"32","author":"JY Lee","year":"2012","unstructured":"Lee JY, Kim KH, Shin KH, Han DH, Lee DY, Nam DH (2012) Comparison of intraoperative complications of phacoemulsification between sequential and combined procedures of pars plana vitrectomy and cataract surgery. Retina 32(10):2026\u20132033. https:\/\/doi.org\/10.1097\/IAE.0b013e3182561fab","journal-title":"Retina"},{"issue":"3","key":"5076_CR35","doi-asserted-by":"publisher","first-page":"805","DOI":"10.3349\/ymj.2015.56.3.805","volume":"56","author":"M Kim","year":"2015","unstructured":"Kim M, Kim HE, Lee DH, Koh HJ, Lee SC, Kim SS (2015) Intraocular lens power estimation in combined phacoemulsification and pars plana vitrectomy in eyes with epiretinal membranes: a case\u2013control study. Yonsei Med J 56(3):805\u2013811. https:\/\/doi.org\/10.3349\/ymj.2015.56.3.805","journal-title":"Yonsei Med J"},{"issue":"7","key":"5076_CR36","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1097\/IAE.0000000000002153","volume":"39","author":"L Shi","year":"2019","unstructured":"Shi L, Chang JS, Suh LH, Chang S (2019) Differences in refractive outcomes between phacoemulsification for cataract alone and combined phacoemulsification and vitrectomy for epiretinal membrane. Retina 39(7):1410\u20131415. https:\/\/doi.org\/10.1097\/IAE.0000000000002153","journal-title":"Retina"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-021-05076-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00417-021-05076-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-021-05076-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T03:53:47Z","timestamp":1626234827000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00417-021-05076-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,25]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["5076"],"URL":"https:\/\/doi.org\/10.1007\/s00417-021-05076-5","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,25]]},"assertion":[{"value":"12 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 January 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 January 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was conducted under the tenets of the National Council of Ethics for the Life Sciences and the Declaration of Helsinki and its latest amendment (Brazil, 2013).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was waived by the local Ethics Committee of all participating centers before study initiation.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent was waived by the local Ethics Committee of all participating centers before study initiation.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}}]}}