{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:30:41Z","timestamp":1757777441268},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2005,9,28]],"date-time":"2005-09-28T00:00:00Z","timestamp":1127865600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Tissue Res"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1007\/s00441-005-0070-7","type":"journal-article","created":{"date-parts":[[2005,9,27]],"date-time":"2005-09-27T15:11:28Z","timestamp":1127833888000},"page":"333-341","source":"Crossref","is-referenced-by-count":17,"title":["Ligand binding and signalling pathways of PTH receptors in sea bream (Sparus auratus) enterocytes"],"prefix":"10.1007","volume":"323","author":[{"given":"J.","family":"Rotllant","sequence":"first","affiliation":[]},{"given":"P. M.","family":"Guerreiro","sequence":"additional","affiliation":[]},{"given":"B.","family":"Redruello","sequence":"additional","affiliation":[]},{"given":"H.","family":"Fernandes","sequence":"additional","affiliation":[]},{"given":"L.","family":"Apol\u00f3nia","sequence":"additional","affiliation":[]},{"given":"L.","family":"Anjos","sequence":"additional","affiliation":[]},{"given":"A. V. M.","family":"Canario","sequence":"additional","affiliation":[]},{"given":"D. M.","family":"Power","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2005,9,28]]},"reference":[{"key":"70_CR1","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1210\/endo-125-4-2215","volume":"125","author":"AB Abou-Samra","year":"1989","unstructured":"Abou-Samra AB, Uneno S, Jueppner H, Keutmann H, Potts JT Jr, Segre GV, Nussbaum SR (1989) Non-homologous sequences of parathyroid hormone and the parathyroid hormone related peptide bind to a common receptor on ROS 17\/2.8 cells. Endocrinology 125: 2215\u20132217","journal-title":"Endocrinology"},{"key":"70_CR2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","volume":"215","author":"SF Altschul","year":"1990","unstructured":"Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403\u2013410","journal-title":"J Mol Biol"},{"key":"70_CR3","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1210\/endo-127-1-83","volume":"127","author":"MP Caulfield","year":"1990","unstructured":"Caulfield MP, McKee RL, Goldman ME, Duong LT, Fisher JE, Gay CT, DeHaven PA, Levy JJ, Roubini E, Nutt RF (1990) The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14\u201334 region. Endocrinology 127:83\u201387","journal-title":"Endocrinology"},{"key":"70_CR4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0005-2736(87)90116-7","volume":"901","author":"JR Castillo Del","year":"1987","unstructured":"Del Castillo JR (1987) The use of hyperosmolar, intracellular-like solutions for the isolation of epithelial cells from guinea-pig small intestine. Biochim Biophys Acta 901:201\u2013208","journal-title":"Biochim Biophys Acta"},{"key":"70_CR5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.cbpb.2004.06.013","volume":"139","author":"R D\u00f3pido","year":"2004","unstructured":"D\u00f3pido R, Rodr\u00edguez C, Gom\u00e9z T, Acosta NG, D\u00edaz M (2004) Isolation and characterization of enterocytes along the intestinal tract of the gilthead seabream (Sparus aurata L.). Comp Biochem Physiol A 139:21\u201331","journal-title":"Comp Biochem Physiol A"},{"key":"70_CR6","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/gcen.2000.7481","volume":"118","author":"JA Flanagan","year":"2000","unstructured":"Flanagan JA, Power DM, Bendell LA, Guerreiro PM, Fuentes J, Clark MS, Canario AV, Danks JA, Brown BL, Ingleton PM (2000) Cloning of the cDNA for sea bream (Sparus aurata) parathyroid hormone-related protein. Gen Comp Endocrinol 118:373\u2013382","journal-title":"Gen Comp Endocrinol"},{"key":"70_CR7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1210\/endo.130.1.1727705","volume":"130","author":"A Fujimori","year":"1992","unstructured":"Fujimori A, Cheng SL, Avioli LV, Civitelli R (1992) Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells. Endocrinology 130:29\u201336","journal-title":"Endocrinology"},{"key":"70_CR8","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S1043-2760(01)00409-X","volume":"12","author":"TJ Gardella","year":"2001","unstructured":"Gardella TJ, Juppner H (2001) Molecular properties of the PTH\/PTHrP receptor. Trends Endocrinol Metab 12:210\u2013217","journal-title":"Trends Endocrinol Metab"},{"key":"70_CR9","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1210\/endo.132.5.8386605","volume":"132","author":"TJ Gardella","year":"1993","unstructured":"Gardella TJ, Wilson AK, Keutmann HT, Oberstein R, Potts JT Jr, Kronenberg M, Nussbaum SR (1993) Analysis of parathyroid hormone's principal receptor-binding region by site-directed mutagenesis and analog design. Endocrinology 132:2024\u20132030","journal-title":"Endocrinology"},{"key":"70_CR10","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1002\/jcb.10472","volume":"88","author":"C Gentili","year":"2003","unstructured":"Gentili C, Morelli S, de Boland AR (2003) Characterization of PTH\/PTHrP receptor in rat duodenum: effects of ageing. J Cell Biochem 88:1157\u20131167","journal-title":"J Cell Biochem"},{"key":"70_CR11","first-page":"R855","volume":"281","author":"PM Guerreiro","year":"2001","unstructured":"Guerreiro PM, Fuentes J, Power DM, Ingleton PM, Flik G, Canario AV (2001) Parathyroid hormone-related protein: a calcium regulatory factor in sea bream (Sparus aurata L.) larvae. Am J Physiol 281:R855\u2013R860","journal-title":"Am J Physiol"},{"key":"70_CR12","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1677\/joe.0.1730377","volume":"173","author":"PM Guerreiro","year":"2002","unstructured":"Guerreiro PM, Fuentes J, Canario AV, Power DM (2002) Calcium balance in sea bream (Sparus aurata): the effect of oestradiol-17b. J Endocrinol 173:377\u2013385","journal-title":"J Endocrinol"},{"key":"70_CR13","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1006\/gcen.1999.7395","volume":"117","author":"T Ieda","year":"2000","unstructured":"Ieda T, Takahashi T, Saito N, Yasuoka T, Kawashima M, Shimada K (2000) Changes in parathyroid hormone-related peptide receptor binding in the shell gland of laying hens (Gallus domesticus) during the oviposition cycle. Gen Comp Endocrinol 117:182\u2013188","journal-title":"Gen Comp Endocrinol"},{"key":"70_CR14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0083-6729(03)01010-0","volume":"66","author":"DA Jans","year":"2003","unstructured":"Jans DA, Thomas RJ, Gillespie MT (2003) Parathyroid hormone-related protein (PTHrP): a nucleocytoplasmic shuttling protein with distinct paracrine and intracrine roles. Vitam Horm 66:345\u2013384","journal-title":"Vitam Horm"},{"key":"70_CR15","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1126\/science.1658941","volume":"254","author":"H Juppner","year":"1991","unstructured":"Juppner H, Abou-Samra A, Freeman M, Kong X, Schipani E, Richards J, Kolakowski L, Hock J, Potts J, Kronenberg H (1991) A G protein-linked receptor for parathyroid hormone and parathyroid hormone-relatyed peptide. Science 254:1024\u20131026","journal-title":"Science"},{"key":"70_CR16","unstructured":"Klein C, Abbas SK, Stewart AF, Care A, Harmeyer J (2001) PTHrP (38\u201394NH2) probably stimulates active absorption of Ca2+ from the duodenum of piglets. 1st Joint Meeting: International Bone and Mineral Society and European Calcified Tissue Society, Comparative Endocrinology of Calcium Regulation, Madrid, p 13"},{"key":"70_CR17","first-page":"864","volume":"73","author":"H Li","year":"1995","unstructured":"Li H, Seitz PK, Thomas ML, Selvanayagam P, Rajaraman S, Cooper CW (1995) Widespread expression of the parathyroid hormone-related peptide and PTH\/PTHrP receptor genes in intestinal epithelial cells. Lab Invest 73:864\u2013870","journal-title":"Lab Invest"},{"key":"70_CR18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265\u2013275","journal-title":"J Biol Chem"},{"key":"70_CR19","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S0955-0674(99)00039-3","volume":"11","author":"A Meyer","year":"1999","unstructured":"Meyer A, Schartl M (1999) Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions. Curr Opin Cell Biol 11:699\u2013704","journal-title":"Curr Opin Cell Biol"},{"key":"70_CR20","first-page":"14","volume":"4","author":"KB Nicholas","year":"1997","unstructured":"Nicholas KB, Nicholas HB Jr, Deerfield DWI (1997) GeneDoc: analysis and visualization of genetic variation. EMBNEW.NEWS 4:14","journal-title":"EMBNEW.NEWS"},{"key":"70_CR21","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1601-5223.1968.tb02169.x","volume":"59","author":"S Ohno","year":"1968","unstructured":"Ohno S, Wolf U, Atkin NB (1968) Evolution from fish to mammals by gene duplication. Hereditas 59:169\u2013187","journal-title":"Hereditas"},{"key":"70_CR22","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1210\/edrv-10-4-476","volume":"10","author":"JJ Orloff","year":"1989","unstructured":"Orloff JJ, Wu TL, Stewart AF (1989) Parathyroid hormone-like proteins: biochemical responses and receptor interactions. Endocr Rev 10:476\u2013495","journal-title":"Endocr Rev"},{"key":"70_CR23","first-page":"40","volume":"15","author":"JJ Orloff","year":"1994","unstructured":"Orloff JJ, Reddy D, de Papp AE, Yang KH, Soifer NE, Stewart AF (1994) Parathyroid hormone-related protein as a prohormone: post-translational processing and receptor interactions. Endocr Rev 15:40\u201360","journal-title":"Endocr Rev"},{"key":"70_CR24","first-page":"181","volume":"4","author":"A Papp","year":"1993","unstructured":"Papp A, Stewart A (1993) Parathyroid hormone-related protein, a peptide of diverse physiologic functions. TEM 4:181\u2013187","journal-title":"TEM"},{"issue":"Suppl 3","key":"70_CR25","first-page":"S169","volume":"7","author":"JT Potts Jr","year":"1997","unstructured":"Potts JT Jr, Gardella TJ, Juppner H, Kronenberg H (1997) The history of parathyroid hormone and its receptor: structure-based design of parathyroid hormone analogues. Osteoporos Int 7(Suppl 3):S169\u2013S173","journal-title":"Osteoporos Int"},{"key":"70_CR26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0378-1119(00)00167-0","volume":"250","author":"DM Power","year":"2000","unstructured":"Power DM, Ingleton PM, Flanagan J, Canario AV, Danks J, Elgar G, Clark MS (2000) Genomic structure and expression of parathyroid hormone-related protein gene (PTHrP) in a teleost, Fugu rubripes. Gene 250:67\u201376","journal-title":"Gene"},{"key":"70_CR27","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1210\/endo.140.4.6613","volume":"140","author":"JL Ramirez","year":"1999","unstructured":"Ramirez JL, Castano JP, Torronteras R, Martinez-Fuentes AJ, Frawley LS, Garcia-Navarro S, Gracia-Navarro F (1999) Growth hormone (GH)-releasing factor differentially activates cyclic adenosine 3',5'-monophosphate- and inositol phosphate-dependent pathways to stimulate GH release in two porcine somatotrope subpopulations. Endocrinology 140:1752\u20131759","journal-title":"Endocrinology"},{"key":"70_CR28","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0016-6480(03)00166-7","volume":"133","author":"J Rotllant","year":"2003","unstructured":"Rotllant J, Worthington GP, Fuentes J, Guerreiro PM, Teitsma CA, Ingleton PM, Balment RJ, Canario AVM, Power DM (2003) Determination of tissue and plasma concentrations of PTHrP in fish: development and validation of a radioimmunoassay using a teleost 1\u201334 N-terminal peptide. Gen Comp Endocrinol 133:146\u2013153","journal-title":"Gen Comp Endocrinol"},{"key":"70_CR29","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1210\/en.2004-0644","volume":"146","author":"J Rotllant","year":"2005","unstructured":"Rotllant J, Guerreiro PM, Anjos L, Redruello B, Canario AVM, Power DM (2005) Stimulation of cortisol release by the N-terminus of teleost parathyroid hormone-related protein in interrenal cells in vitro. Endocrinology 146:71\u201376","journal-title":"Endocrinology"},{"key":"70_CR30","doi-asserted-by":"crossref","first-page":"28185","DOI":"10.1074\/jbc.274.40.28185","volume":"274","author":"DA Rubin","year":"1999","unstructured":"Rubin DA, Juppner H (1999) Zebrafish express the common parathyroid hormone\/parathyroid hormone-related peptide receptor (PTH1R) and a novel receptor (PTH3R) that is preferentially activated by mammalian and fugufish parathyroid hormone-related peptide. J Biol Chem 274:28185\u201328190","journal-title":"J Biol Chem"},{"key":"70_CR31","doi-asserted-by":"crossref","first-page":"23035","DOI":"10.1074\/jbc.274.33.23035","volume":"274","author":"DA Rubin","year":"1999","unstructured":"Rubin DA, Hellman P, Zon LI, Lobb CJ, Bergwitz C, Juppner H (1999) A G protein-coupled receptor from zebrafish is activated by human parathyroid hormone and not by human or teleost parathyroid hormone-related peptide\u2014implications for the evolutionary conservation of calcium-regulating peptide hormones. J Biol Chem 274:23035\u201323042","journal-title":"J Biol Chem"},{"key":"70_CR32","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/j.1749-6632.1949.tb27297.x","volume":"51","author":"G Scatchard","year":"1949","unstructured":"Scatchard G (1949) The attractions of proteins for small molecules and ions. Ann N Y Acad Sci 51:660\u2013672","journal-title":"Ann N Y Acad Sci"},{"key":"70_CR33","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0002-9343(99)00294-6","volume":"107","author":"SJ Silverberg","year":"1999","unstructured":"Silverberg SJ, Shane E, Dempster DW, Bilezikian JP (1999) The effects of vitamin D insufficiency in patients with primary hyperparathyroidism. Am J Med 107:561\u2013567","journal-title":"Am J Med"},{"key":"70_CR34","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1359\/jbmr.2000.15.6.1033","volume":"15","author":"PH Watson","year":"2000","unstructured":"Watson PH, Fraher LJ, Hendy GN, Chung UI, Kisiel M, Natale BV, Hodsman AB (2000) Nuclear localization of the type 1 PTH\/PTHrP receptor in rat tissues. J Bone Miner Res 15:1033\u20131044","journal-title":"J Bone Miner Res"},{"key":"70_CR35","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1146\/annurev.physiol.60.1.431","volume":"60","author":"J Wysolmerski","year":"1998","unstructured":"Wysolmerski J, Stewart A (1998) The physiology of parathyroid hormone-related protein: an emerging role as a development factor. Annu Rev Physiol 60:431\u2013460","journal-title":"Annu Rev Physiol"},{"key":"70_CR36","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1002\/jbmr.5650111212","volume":"11","author":"T Yasuoka","year":"1996","unstructured":"Yasuoka T, Kawashima M, Takahashi T, Iwata A, Oka N, Tanaka K (1996) Changes in parathyroid hormone receptor binding affinity during egg laying\u2014implications for calcium homeostasis in chicken. J Bone Miner Res 11:1913\u20131920","journal-title":"J Bone Miner Res"},{"key":"70_CR37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0006-291X(05)80776-4","volume":"186","author":"LX Zhou","year":"1992","unstructured":"Zhou LX, Nemere I, Norman AW (1992) A parathyroid-related peptide induces transcaltachia (the rapid, hormonal stimulation of intestinal Ca2+ transport). Biochem Biophys Res Commun 186:69\u201373","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Cell and Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-005-0070-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00441-005-0070-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00441-005-0070-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,18]],"date-time":"2021-07-18T03:43:32Z","timestamp":1626579812000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00441-005-0070-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9,28]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["70"],"URL":"https:\/\/doi.org\/10.1007\/s00441-005-0070-7","relation":{},"ISSN":["0302-766X","1432-0878"],"issn-type":[{"value":"0302-766X","type":"print"},{"value":"1432-0878","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,9,28]]}}}